DK1907371T3 - Fremgangsmåde til fremstilling af 2-methoxycarbonyl-methyl-6,6-dimethyl-2- tetrahydropyrancarboxylsyre - Google Patents
Fremgangsmåde til fremstilling af 2-methoxycarbonyl-methyl-6,6-dimethyl-2- tetrahydropyrancarboxylsyreInfo
- Publication number
- DK1907371T3 DK1907371T3 DK06792504.0T DK06792504T DK1907371T3 DK 1907371 T3 DK1907371 T3 DK 1907371T3 DK 06792504 T DK06792504 T DK 06792504T DK 1907371 T3 DK1907371 T3 DK 1907371T3
- Authority
- DK
- Denmark
- Prior art keywords
- methyl
- dimethyl
- acid
- methoxycarbonylmethyl
- heptenoate
- Prior art date
Links
- RLJJTHIETVMNAO-UHFFFAOYSA-N 2-(2-methoxy-2-oxoethyl)-6,6-dimethyloxane-2-carboxylic acid Chemical compound COC(=O)CC1(C(O)=O)CCCC(C)(C)O1 RLJJTHIETVMNAO-UHFFFAOYSA-N 0.000 title abstract 4
- DRFNZQPZTGLTJC-UHFFFAOYSA-N 2-hydroxy-2-(4-methylpent-3-enyl)butanedioic acid Chemical compound CC(C)=CCCC(O)(C(O)=O)CC(O)=O DRFNZQPZTGLTJC-UHFFFAOYSA-N 0.000 abstract 4
- BEDDBBCLHNGXGD-UHFFFAOYSA-N ethyl 6-methyl-2-oxohept-5-enoate Chemical compound CCOC(=O)C(=O)CCC=C(C)C BEDDBBCLHNGXGD-UHFFFAOYSA-N 0.000 abstract 4
- AJBWTDQJHHDXPL-UHFFFAOYSA-N 2-(carboxymethyl)-6,6-dimethyloxane-2-carboxylic acid Chemical compound CC1(C)CCCC(CC(O)=O)(C(O)=O)O1 AJBWTDQJHHDXPL-UHFFFAOYSA-N 0.000 abstract 3
- NBOWWOOUDLBQFP-UHFFFAOYSA-N 1-o-ethyl 4-o-methyl 2-hydroxy-2-(4-methylpent-3-enyl)butanedioate Chemical compound CCOC(=O)C(O)(CC(=O)OC)CCC=C(C)C NBOWWOOUDLBQFP-UHFFFAOYSA-N 0.000 abstract 2
- UNXURIHDFUQNOC-UHFFFAOYSA-N 5-bromo-2-methylpent-2-ene Chemical compound CC(C)=CCCBr UNXURIHDFUQNOC-UHFFFAOYSA-N 0.000 abstract 2
- PAFZNILMFXTMIY-UHFFFAOYSA-N cyclohexylamine Chemical compound NC1CCCCC1 PAFZNILMFXTMIY-UHFFFAOYSA-N 0.000 abstract 2
- BDAGIHXWWSANSR-UHFFFAOYSA-N methanoic acid Natural products OC=O BDAGIHXWWSANSR-UHFFFAOYSA-N 0.000 abstract 2
- OSWFIVFLDKOXQC-UHFFFAOYSA-N 4-(3-methoxyphenyl)aniline Chemical compound COC1=CC=CC(C=2C=CC(N)=CC=2)=C1 OSWFIVFLDKOXQC-UHFFFAOYSA-N 0.000 abstract 1
- FYYHWMGAXLPEAU-UHFFFAOYSA-N Magnesium Chemical compound [Mg] FYYHWMGAXLPEAU-UHFFFAOYSA-N 0.000 abstract 1
- XBDQKXXYIPTUBI-UHFFFAOYSA-M Propionate Chemical compound CCC([O-])=O XBDQKXXYIPTUBI-UHFFFAOYSA-M 0.000 abstract 1
- KXKVLQRXCPHEJC-UHFFFAOYSA-N acetic acid trimethyl ester Natural products COC(C)=O KXKVLQRXCPHEJC-UHFFFAOYSA-N 0.000 abstract 1
- 239000003513 alkali Substances 0.000 abstract 1
- 150000008044 alkali metal hydroxides Chemical class 0.000 abstract 1
- 150000001408 amides Chemical class 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- WYACBZDAHNBPPB-UHFFFAOYSA-N diethyl oxalate Chemical compound CCOC(=O)C(=O)OCC WYACBZDAHNBPPB-UHFFFAOYSA-N 0.000 abstract 1
- 235000019253 formic acid Nutrition 0.000 abstract 1
- 229910052749 magnesium Inorganic materials 0.000 abstract 1
- 239000011777 magnesium Substances 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C211/00—Compounds containing amino groups bound to a carbon skeleton
- C07C211/33—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of rings other than six-membered aromatic rings
- C07C211/34—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of rings other than six-membered aromatic rings of a saturated carbon skeleton
- C07C211/35—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of rings other than six-membered aromatic rings of a saturated carbon skeleton containing only non-condensed rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pyrane Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT001352A ITMI20051352A1 (it) | 2005-07-15 | 2005-07-15 | Processo di preparazi0ne di acido 2-metossicarbonilmetil-6,6-dimetil-2-tetraidropiran carbossilico |
| PCT/EP2006/064273 WO2007009953A1 (en) | 2005-07-15 | 2006-07-14 | Process for preparing 2-methoxycarbonylmethyl-6,6-dimethyl-2- tetrahydropyran carboxylic acid |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1907371T3 true DK1907371T3 (da) | 2012-03-19 |
Family
ID=36087589
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK06792504.0T DK1907371T3 (da) | 2005-07-15 | 2006-07-14 | Fremgangsmåde til fremstilling af 2-methoxycarbonyl-methyl-6,6-dimethyl-2- tetrahydropyrancarboxylsyre |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US8008514B2 (OSRAM) |
| EP (1) | EP1907371B1 (OSRAM) |
| JP (1) | JP2009501196A (OSRAM) |
| CN (1) | CN101233123B (OSRAM) |
| AT (1) | ATE534640T1 (OSRAM) |
| CY (1) | CY1112967T1 (OSRAM) |
| DK (1) | DK1907371T3 (OSRAM) |
| ES (1) | ES2378081T3 (OSRAM) |
| IT (1) | ITMI20051352A1 (OSRAM) |
| PL (1) | PL1907371T3 (OSRAM) |
| PT (1) | PT1907371E (OSRAM) |
| SI (1) | SI1907371T1 (OSRAM) |
| WO (1) | WO2007009953A1 (OSRAM) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103910659B (zh) * | 2013-11-04 | 2016-05-11 | 迈克斯(如东)化工有限公司 | 2-硝基-4-甲磺酰基苯甲酸的精制方法及其中间体 |
| US10597401B2 (en) | 2015-05-08 | 2020-03-24 | Albany Molecular Research, Inc. | Methods and intermediates for the preparation of omacetaxine and cephalotaxine derivatives thereof |
| EP3275875A1 (en) | 2016-07-28 | 2018-01-31 | INDENA S.p.A. | Dioxolanone intermediate useful in the synthesis of homoharringtonine |
| CN110577803B (zh) | 2018-06-11 | 2021-11-26 | 3M创新有限公司 | 一种阻燃压敏胶粘合剂、阻燃压敏胶粘合片及其制备方法 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0377862A (ja) * | 1989-08-18 | 1991-04-03 | Ono Pharmaceut Co Ltd | ビシクロ［２．２．１］ヘプタン誘導体、その精製方法および製造方法 |
| FR2776292B1 (fr) | 1998-03-20 | 2004-09-10 | Oncopharm | Cephalotaxanes porteurs de chaine laterale et leur procede de synthese |
| JP2001163841A (ja) * | 1999-09-30 | 2001-06-19 | Dai Ichi Seiyaku Co Ltd | 光学活性な２−（２，３，４―トリハロゲノアニリノ）−プロピオン酸誘導体の製法 |
| WO2004096785A1 (ja) * | 2003-04-25 | 2004-11-11 | Nippon Chemiphar Co., Ltd. | （２s，３s）－３－［［（１s）－１－イソブトキシメチル－３－メチルブチル］カルバモイル］オキシラン－２－カルボン酸の塩 |
-
2005
- 2005-07-15 IT IT001352A patent/ITMI20051352A1/it unknown
-
2006
- 2006-07-14 JP JP2008520889A patent/JP2009501196A/ja active Pending
- 2006-07-14 DK DK06792504.0T patent/DK1907371T3/da active
- 2006-07-14 ES ES06792504T patent/ES2378081T3/es active Active
- 2006-07-14 SI SI200631271T patent/SI1907371T1/sl unknown
- 2006-07-14 AT AT06792504T patent/ATE534640T1/de active
- 2006-07-14 CN CN2006800258750A patent/CN101233123B/zh not_active Expired - Fee Related
- 2006-07-14 PT PT06792504T patent/PT1907371E/pt unknown
- 2006-07-14 US US11/988,856 patent/US8008514B2/en not_active Expired - Fee Related
- 2006-07-14 PL PL06792504T patent/PL1907371T3/pl unknown
- 2006-07-14 EP EP06792504A patent/EP1907371B1/en not_active Not-in-force
- 2006-07-14 WO PCT/EP2006/064273 patent/WO2007009953A1/en not_active Ceased
-
2012
- 2012-02-23 CY CY20121100192T patent/CY1112967T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| SI1907371T1 (sl) | 2012-04-30 |
| ATE534640T1 (de) | 2011-12-15 |
| PL1907371T3 (pl) | 2012-09-28 |
| ITMI20051352A1 (it) | 2007-01-16 |
| US8008514B2 (en) | 2011-08-30 |
| CN101233123B (zh) | 2011-05-11 |
| EP1907371A1 (en) | 2008-04-09 |
| CN101233123A (zh) | 2008-07-30 |
| ES2378081T3 (es) | 2012-04-04 |
| PT1907371E (pt) | 2012-03-06 |
| JP2009501196A (ja) | 2009-01-15 |
| EP1907371B1 (en) | 2011-11-23 |
| WO2007009953A1 (en) | 2007-01-25 |
| CY1112967T1 (el) | 2016-04-13 |
| US20090043093A1 (en) | 2009-02-12 |
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