DK189185A - (6,11-dihydro-11-oxodibenz(b,e)oxepinyl)-pentanoler, deres fremstilling og anvendelse - Google Patents

(6,11-dihydro-11-oxodibenz(b,e)oxepinyl)-pentanoler, deres fremstilling og anvendelse Download PDF

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Publication number
DK189185A
DK189185A DK189185A DK189185A DK189185A DK 189185 A DK189185 A DK 189185A DK 189185 A DK189185 A DK 189185A DK 189185 A DK189185 A DK 189185A DK 189185 A DK189185 A DK 189185A
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Prior art keywords
oxodibenz
pentanols
oxepinyl
dihydro
preparation
Prior art date
Application number
DK189185A
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English (en)
Other versions
DK189185D0 (da
Inventor
Lawrence L Martin
Linda L Setescak
Original Assignee
Hoechst Roussel Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Hoechst Roussel Pharma filed Critical Hoechst Roussel Pharma
Publication of DK189185D0 publication Critical patent/DK189185D0/da
Publication of DK189185A publication Critical patent/DK189185A/da

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C37/00Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring
    • C07C37/50Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring by reactions decreasing the number of carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D313/00Heterocyclic compounds containing rings of more than six members having one oxygen atom as the only ring hetero atom
    • C07D313/02Seven-membered rings
    • C07D313/06Seven-membered rings condensed with carbocyclic rings or ring systems
    • C07D313/10Seven-membered rings condensed with carbocyclic rings or ring systems condensed with two six-membered rings
    • C07D313/12[b,e]-condensed

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Rheumatology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pain & Pain Management (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Description

Figure DK189185AD00021
der også er hidtil ukendt, cycliseres i nærværelse af et dehydratiseringsmiddel, hvorefter forbindelsen med formlen I, hvori R betyder hydrogen, eventuelt esterificeres på sædvanlig måde.
Forbindelserne I kan anvendes i lægemidler til undertrykkelse af inflammation af arthritis-typen.
DK189185A 1984-04-27 1985-04-26 (6,11-dihydro-11-oxodibenz(b,e)oxepinyl)-pentanoler, deres fremstilling og anvendelse DK189185A (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US60454584A 1984-04-27 1984-04-27
US60454584 1984-04-27

Publications (2)

Publication Number Publication Date
DK189185D0 DK189185D0 (da) 1985-04-26
DK189185A true DK189185A (da) 1985-10-28

Family

ID=24420026

Family Applications (1)

Application Number Title Priority Date Filing Date
DK189185A DK189185A (da) 1984-04-27 1985-04-26 (6,11-dihydro-11-oxodibenz(b,e)oxepinyl)-pentanoler, deres fremstilling og anvendelse

Country Status (8)

Country Link
EP (1) EP0160258B1 (da)
JP (1) JPS615073A (da)
AT (1) ATE46693T1 (da)
DE (1) DE3573257D1 (da)
DK (1) DK189185A (da)
ES (1) ES8608504A1 (da)
GR (1) GR851013B (da)
PT (1) PT80360B (da)

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
YU204274A (en) * 1973-07-24 1982-06-30 Hoechst Ag Process for preparing new dibenzoxepin derivatives
JPS55124777A (en) * 1979-03-20 1980-09-26 Toa Eiyou Kagaku Kogyo Kk Novel dibenzoxepin derivative and its preparation

Also Published As

Publication number Publication date
DE3573257D1 (en) 1989-11-02
DK189185D0 (da) 1985-04-26
EP0160258B1 (en) 1989-09-27
ATE46693T1 (de) 1989-10-15
EP0160258A2 (en) 1985-11-06
PT80360A (en) 1985-05-01
PT80360B (en) 1987-02-11
JPS615073A (ja) 1986-01-10
ES8608504A1 (es) 1986-06-16
EP0160258A3 (en) 1986-10-08
GR851013B (da) 1985-11-25
ES542554A0 (es) 1986-06-16

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