DK1841863T3 - Fremgangsmåde til rensning af faktor VII - Google Patents

Fremgangsmåde til rensning af faktor VII

Info

Publication number
DK1841863T3
DK1841863T3 DK06700982.9T DK06700982T DK1841863T3 DK 1841863 T3 DK1841863 T3 DK 1841863T3 DK 06700982 T DK06700982 T DK 06700982T DK 1841863 T3 DK1841863 T3 DK 1841863T3
Authority
DK
Denmark
Prior art keywords
factor vii
purifying factor
purifying
rfvii
rfviia
Prior art date
Application number
DK06700982.9T
Other languages
English (en)
Inventor
Frank Bech Nygaard
Rikkle Bolding Jensen
Original Assignee
Bayer Healthcare Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Healthcare Llc filed Critical Bayer Healthcare Llc
Application granted granted Critical
Publication of DK1841863T3 publication Critical patent/DK1841863T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/6437—Coagulation factor VIIa (3.4.21.21)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21—Serine endopeptidases (3.4.21)
    • C12Y304/21021—Coagulation factor VIIa (3.4.21.21)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Saccharide Compounds (AREA)
  • Processing Of Solid Wastes (AREA)
DK06700982.9T 2005-01-14 2006-01-13 Fremgangsmåde til rensning af faktor VII DK1841863T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US64412605P 2005-01-14 2005-01-14
PCT/DK2006/000024 WO2006074664A1 (en) 2005-01-14 2006-01-13 Method for purification of factor vii

Publications (1)

Publication Number Publication Date
DK1841863T3 true DK1841863T3 (da) 2010-11-29

Family

ID=36010990

Family Applications (1)

Application Number Title Priority Date Filing Date
DK06700982.9T DK1841863T3 (da) 2005-01-14 2006-01-13 Fremgangsmåde til rensning af faktor VII

Country Status (10)

Country Link
US (1) US20090047723A1 (da)
EP (1) EP1841863B1 (da)
AT (1) ATE476501T1 (da)
CY (1) CY1110867T1 (da)
DE (1) DE602006015907D1 (da)
DK (1) DK1841863T3 (da)
ES (1) ES2349112T3 (da)
PL (1) PL1841863T3 (da)
PT (1) PT1841863E (da)
WO (1) WO2006074664A1 (da)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101184474B (zh) * 2005-04-28 2013-05-29 诺和诺德医疗保健公司 含有活化的凝血因子ⅶ多肽的密封容器，制备这种容器的方法，和试剂盒以及该试剂盒的使用方法
FR2901796A1 (fr) * 2006-05-31 2007-12-07 Lab Francais Du Fractionnement Procede d'extraction d'une ou de plusieurs proteines presentes dans du lait
BRPI1015176B1 (pt) * 2009-06-16 2019-10-29 Genzyme Corp método para isolar uma população de partículas de vírus adenoassociado recombinante (raav) de impurezas de processo em uma corrente de alimentação
CA2787009C (en) 2010-01-15 2018-04-03 Bio-Rad Laboratories, Inc. Surface neutralization of apatite
US8895707B2 (en) 2010-08-18 2014-11-25 Bio-Rad Laboratories, Inc. Elution of proteins from hydroxyapatite resins without resin deterioration
AR083035A1 (es) 2010-09-17 2013-01-30 Baxter Int ESTABILIZACION DE INMUNOGLOBULINAS MEDIANTE UNA FORMULACION ACUOSA CON HISTIDINA A pH ACIDO DEBIL A NEUTRO, COMPOSICION ACUOSA DE INMUNOGLOBULINA
SG191186A1 (en) 2010-12-15 2013-07-31 Baxter Int Eluate collection using conductivity gradient
US9592540B2 (en) 2011-02-02 2017-03-14 Bio-Rad Laboratories, Inc. Apatite surface neutralization with alkali solutions
WO2013180933A1 (en) 2012-05-30 2013-12-05 Bio-Rad Laboratories, Inc. In situ restoration of apatite-based chromatography resins
WO2013180647A1 (en) * 2012-05-31 2013-12-05 Agency For Science, Technology And Research Chromatographic purification of immunoglobulin g preparations with particles having multimodal functionalities
US9175279B1 (en) 2013-03-15 2015-11-03 Csl Limited Method of purifying factor VII and/or factor VIIa
US9802822B2 (en) 2014-06-23 2017-10-31 Bio-Rad Laboratories, Inc. Apatite pretreatment
CN105407917B (zh) 2014-06-23 2021-07-06 生物辐射实验室股份有限公司 磷灰石原位恢复
MX2019002734A (es) 2016-09-13 2019-05-27 Bayer Healthcare Llc Glicoformas del factor viia.

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4470969A (en) * 1983-12-02 1984-09-11 Miles Laboratories, Inc. Process for producing a concentrate of coagulation factors VII and VIIa
US4473553A (en) * 1983-12-02 1984-09-25 Miles Laboratories, Inc. Process for producing a lipoprotein-poor concentrate of coagulation factors VII and VIIa
US4637932A (en) * 1984-10-15 1987-01-20 Miles Laboratories, Inc. Process for producing a concentrate enriched in coagulation factors VII and VIIa
US4981952A (en) * 1988-10-04 1991-01-01 Eli Lilly And Company Method for the purification of vitamin K-dependent proteins
DK38293D0 (da) * 1993-03-31 1993-03-31 Novo Nordisk As Fremstilling af proteiner
DE4406515C1 (de) * 1994-02-28 1995-10-19 Immuno Ag Verfahren zur Isolierung und Reinigung Vitamin K-abhängiger Proteine
AT408613B (de) * 1998-06-17 2002-01-25 Immuno Ag Pharmazeutisches faktor vii-präparat
US6451987B1 (en) * 1999-03-15 2002-09-17 Novo Nordisk A/S Ion exchange chromatography of proteins and peptides
DE19937218A1 (de) * 1999-08-06 2001-02-08 Aventis Behring Gmbh Verfahren zur Reindarstellung der den Blutgerinnungsfaktor VII aktivierenden Protease, ihres Proenzyms oder eines Gemisches beider Proteine mittels Affinitätschromatographie
US7897734B2 (en) * 2003-03-26 2011-03-01 Novo Nordisk Healthcare Ag Method for the production of proteins
US20070037966A1 (en) * 2004-05-04 2007-02-15 Novo Nordisk A/S Hydrophobic interaction chromatography purification of factor VII polypeptides

Also Published As

Publication number Publication date
US20090047723A1 (en) 2009-02-19
EP1841863B1 (en) 2010-08-04
EP1841863A1 (en) 2007-10-10
DE602006015907D1 (de) 2010-09-16
PT1841863E (pt) 2010-10-25
PL1841863T3 (pl) 2011-05-31
ES2349112T3 (es) 2010-12-28
WO2006074664A1 (en) 2006-07-20
ATE476501T1 (de) 2010-08-15
CY1110867T1 (el) 2015-06-10

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