DK1817061T3 - Elektroporering af Mycobacterium og overekspression af antigener i Mycobacteria - Google Patents
Elektroporering af Mycobacterium og overekspression af antigener i MycobacteriaInfo
- Publication number
- DK1817061T3 DK1817061T3 DK05852317.6T DK05852317T DK1817061T3 DK 1817061 T3 DK1817061 T3 DK 1817061T3 DK 05852317 T DK05852317 T DK 05852317T DK 1817061 T3 DK1817061 T3 DK 1817061T3
- Authority
- DK
- Denmark
- Prior art keywords
- mycobacteria
- mycobacterium
- overexpression
- electroporation
- antigens
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/04—Mycobacterium, e.g. Mycobacterium tuberculosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
- C07H21/02—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with ribosyl as saccharide radical
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/52—Bacterial cells; Fungal cells; Protozoal cells
- A61K2039/523—Bacterial cells; Fungal cells; Protozoal cells expressing foreign proteins
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- General Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Zoology (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Plant Pathology (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Communicable Diseases (AREA)
- Mycology (AREA)
- Pulmonology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US63197704P | 2004-12-01 | 2004-12-01 | |
| PCT/US2005/042976 WO2006060332A2 (en) | 2004-12-01 | 2005-11-29 | Electroporation of mycobacterium and overexpression of antigens in mycobacteria |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1817061T3 true DK1817061T3 (da) | 2011-11-14 |
Family
ID=36565595
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK05852317.6T DK1817061T3 (da) | 2004-12-01 | 2005-11-29 | Elektroporering af Mycobacterium og overekspression af antigener i Mycobacteria |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US7625572B2 (da) |
| EP (1) | EP1817061B1 (da) |
| JP (1) | JP5461776B2 (da) |
| KR (1) | KR101382215B1 (da) |
| CN (1) | CN101076356B (da) |
| AP (1) | AP2869A (da) |
| AT (1) | ATE517637T1 (da) |
| AU (1) | AU2005312062B2 (da) |
| BR (1) | BRPI0518080A (da) |
| CA (1) | CA2587507C (da) |
| DK (1) | DK1817061T3 (da) |
| EA (1) | EA012182B1 (da) |
| ES (1) | ES2370885T3 (da) |
| MX (1) | MX2007006552A (da) |
| WO (1) | WO2006060332A2 (da) |
| ZA (1) | ZA200704764B (da) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7829104B2 (en) * | 2004-12-01 | 2010-11-09 | Aeras Global Tb Vaccine Foundation | Electroporation of Mycobacterium and overexpression of antigens in mycobacteria |
| CN101198358B (zh) | 2004-12-01 | 2013-06-26 | Aeras全球Tb疫苗基金会 | 具有增强的逃出内体能力的重组bcg菌株 |
| US8682619B2 (en) * | 2005-12-14 | 2014-03-25 | The Invention Science Fund I, Llc | Device including altered microorganisms, and methods and systems of use |
| US8278094B2 (en) | 2005-12-14 | 2012-10-02 | The Invention Science Fund I, Llc | Bone semi-permeable device |
| US20110172826A1 (en) * | 2005-12-14 | 2011-07-14 | Amodei Dario G | Device including altered microorganisms, and methods and systems of use |
| US8734823B2 (en) * | 2005-12-14 | 2014-05-27 | The Invention Science Fund I, Llc | Device including altered microorganisms, and methods and systems of use |
| US8852916B2 (en) * | 2010-01-22 | 2014-10-07 | The Invention Science Fund I, Llc | Compositions and methods for therapeutic delivery with microorganisms |
| BRPI0620693A2 (pt) * | 2005-12-15 | 2016-12-13 | Aeras Global Tb Vaccine Found | método para suscitar uma resposta imune tanto sistêmica como de mucosa a mycobacteria viva atenuada ou antígenos micobacterianos em um hospedeiro |
| US8932846B2 (en) * | 2007-06-14 | 2015-01-13 | The Regents Of The University Of California | Unmarked recombinant intracellular pathogen immunogenic compositions expressing high levels of recombinant proteins |
| EP2834356A4 (en) * | 2012-04-02 | 2015-09-02 | Univ Arizona | RECOMBINANT BACTERIUM FOR INDUCING A CELLULAR IMMUNE RESPONSE |
| US9926346B2 (en) | 2012-04-16 | 2018-03-27 | Aeras | Recombinant mycobacterium encoding a heparin-binding hemagglutinin (HBHA) fusion protein and uses thereof |
| US10973908B1 (en) | 2020-05-14 | 2021-04-13 | David Gordon Bermudes | Expression of SARS-CoV-2 spike protein receptor binding domain in attenuated salmonella as a vaccine |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5736367A (en) * | 1992-03-31 | 1998-04-07 | Medimmune, Inc. | Vectors and prokaryotes which autocatalytically delete antibiotic resistance |
| US5783386A (en) * | 1994-02-24 | 1998-07-21 | Agresearch, New Zealand Pastoral Agriculture Research Institute Ltd. | Mycobacteria virulence factors and a novel method for their identification |
| ATE258986T1 (de) * | 1994-07-29 | 2004-02-15 | Ajinomoto Kk | Sekretorischer rekombinanter bcg impfstoff gegen aids |
| US5736524A (en) * | 1994-11-14 | 1998-04-07 | Merck & Co.,. Inc. | Polynucleotide tuberculosis vaccine |
| US6004815A (en) * | 1998-08-13 | 1999-12-21 | The Regents Of The University Of California | Bacteria expressing nonsecreted cytolysin as intracellular microbial delivery vehicles to eukaryotic cells |
| US6562348B2 (en) * | 1999-07-08 | 2003-05-13 | Albert Einstein College Of Medicine Of Yeshiva University | Recombinant M. tuberculosis auxotrophic for leucine and vaccines using same |
| US6423545B1 (en) * | 1999-07-08 | 2002-07-23 | Albert Einstein College Of Medicine Of Yeshiva University | Unmarked deletion mutants of mycobacteria and methods of using same |
| CN1342771A (zh) * | 2001-09-17 | 2002-04-03 | 复旦大学 | 结核分枝杆菌Ag85B抗原的表达纯化和作为疫苗组份的应用 |
| KR20070108518A (ko) * | 2005-01-05 | 2007-11-12 | 아이시스 이노베이션 리미티드 | 마이코박테리움에 대한 면역성을 제공하기 위한 조성물들 |
-
2005
- 2005-11-29 WO PCT/US2005/042976 patent/WO2006060332A2/en active Application Filing
- 2005-11-29 US US11/288,424 patent/US7625572B2/en active Active
- 2005-11-29 KR KR1020077015172A patent/KR101382215B1/ko active IP Right Grant
- 2005-11-29 BR BRPI0518080-5A patent/BRPI0518080A/pt not_active Application Discontinuation
- 2005-11-29 AP AP2007004021A patent/AP2869A/xx active
- 2005-11-29 EP EP05852317A patent/EP1817061B1/en active Active
- 2005-11-29 JP JP2007544419A patent/JP5461776B2/ja active Active
- 2005-11-29 AU AU2005312062A patent/AU2005312062B2/en active Active
- 2005-11-29 CN CN2005800414379A patent/CN101076356B/zh active Active
- 2005-11-29 DK DK05852317.6T patent/DK1817061T3/da active
- 2005-11-29 CA CA2587507A patent/CA2587507C/en not_active Expired - Fee Related
- 2005-11-29 EA EA200701130A patent/EA012182B1/ru unknown
- 2005-11-29 AT AT05852317T patent/ATE517637T1/de not_active IP Right Cessation
- 2005-11-29 ZA ZA200704764A patent/ZA200704764B/xx unknown
- 2005-11-29 MX MX2007006552A patent/MX2007006552A/es active IP Right Grant
- 2005-11-29 ES ES05852317T patent/ES2370885T3/es active Active
Also Published As
| Publication number | Publication date |
|---|---|
| AU2005312062A1 (en) | 2006-06-08 |
| AP2007004021A0 (en) | 2007-06-30 |
| AP2869A (en) | 2014-03-31 |
| CN101076356A (zh) | 2007-11-21 |
| CA2587507A1 (en) | 2006-06-08 |
| EA200701130A1 (ru) | 2007-12-28 |
| EP1817061A4 (en) | 2009-07-08 |
| ZA200704764B (en) | 2008-09-25 |
| MX2007006552A (es) | 2007-08-20 |
| WO2006060332A2 (en) | 2006-06-08 |
| CA2587507C (en) | 2013-11-19 |
| EP1817061A2 (en) | 2007-08-15 |
| CN101076356B (zh) | 2013-04-03 |
| JP5461776B2 (ja) | 2014-04-02 |
| JP2008521435A (ja) | 2008-06-26 |
| WO2006060332A3 (en) | 2006-08-03 |
| US7625572B2 (en) | 2009-12-01 |
| BRPI0518080A (pt) | 2008-10-28 |
| EP1817061B1 (en) | 2011-07-27 |
| ATE517637T1 (de) | 2011-08-15 |
| AU2005312062B2 (en) | 2011-11-17 |
| KR20070111452A (ko) | 2007-11-21 |
| ES2370885T3 (es) | 2011-12-23 |
| US20060121054A1 (en) | 2006-06-08 |
| EA012182B1 (ru) | 2009-08-28 |
| KR101382215B1 (ko) | 2014-04-08 |
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