DK1801233T3 - Diagnostisk fremgangsmåde til genkendelse af bærere af Marburg I-varianten af den faktor VII-aktiverende protease (FSAP) ved differentiel modulering af FSAP-aktiviteten - Google Patents

Diagnostisk fremgangsmåde til genkendelse af bærere af Marburg I-varianten af den faktor VII-aktiverende protease (FSAP) ved differentiel modulering af FSAP-aktiviteten

Info

Publication number
DK1801233T3
DK1801233T3 DK06024985.1T DK06024985T DK1801233T3 DK 1801233 T3 DK1801233 T3 DK 1801233T3 DK 06024985 T DK06024985 T DK 06024985T DK 1801233 T3 DK1801233 T3 DK 1801233T3
Authority
DK
Denmark
Prior art keywords
fsap
variant
marburg
diagnostic method
factor vii
Prior art date
Application number
DK06024985.1T
Other languages
English (en)
Inventor
Frank Dr Vitzthum
Herbert Schwarz
Original Assignee
Siemens Healthcare Diagnostics
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE200510062055 external-priority patent/DE102005062055A1/de
Priority claimed from DE200510062053 external-priority patent/DE102005062053A1/de
Application filed by Siemens Healthcare Diagnostics filed Critical Siemens Healthcare Diagnostics
Application granted granted Critical
Publication of DK1801233T3 publication Critical patent/DK1801233T3/da

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
    • C12Q1/37—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving peptidase or proteinase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/56—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving blood clotting factors, e.g. involving thrombin, thromboplastin, fibrinogen
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/86—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood coagulating time or factors, or their receptors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/81—Protease inhibitors
    • G01N2333/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
    • G01N2333/811—Serine protease (E.C. 3.4.21) inhibitors
    • G01N2333/8114—Kunitz type inhibitors
    • G01N2333/8117—Bovine/basic pancreatic trypsin inhibitor (BPTI, aprotinin)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/914—Hydrolases (3)
    • G01N2333/948—Hydrolases (3) acting on peptide bonds (3.4)
    • G01N2333/95—Proteinases, i.e. endopeptidases (3.4.21-3.4.99)
    • G01N2333/964—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue
    • G01N2333/96425—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals
    • G01N2333/96427—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals in general
    • G01N2333/9643—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals in general with EC number
    • G01N2333/96433—Serine endopeptidases (3.4.21)
    • G01N2333/96441—Serine endopeptidases (3.4.21) with definite EC number
    • G01N2333/96447—Factor VII (3.4.21.21)

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Urology & Nephrology (AREA)
  • Wood Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cell Biology (AREA)
  • Biophysics (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Neurosurgery (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
DK06024985.1T 2005-12-22 2006-12-04 Diagnostisk fremgangsmåde til genkendelse af bærere af Marburg I-varianten af den faktor VII-aktiverende protease (FSAP) ved differentiel modulering af FSAP-aktiviteten DK1801233T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE200510062055 DE102005062055A1 (de) 2005-12-22 2005-12-22 Diagnostisches Verfahren zur Erkennung von Trägern der Marburg I-Variante der Faktor VII-aktivierenden Protease (FSAP) anhand der differenziellen Modulation der FSAP-Aktivität in einem einzigen Reaktionsansatz
DE200510062053 DE102005062053A1 (de) 2005-12-22 2005-12-22 Diagnostisches Verfahren zur Erkennung von Trägern der Marburg I-Variante der Faktor VII-aktivierenden Protease (FSAP) anhand differenzieller Modulation der FSAP-Aktivität

Publications (1)

Publication Number Publication Date
DK1801233T3 true DK1801233T3 (da) 2010-02-08

Family

ID=37733048

Family Applications (1)

Application Number Title Priority Date Filing Date
DK06024985.1T DK1801233T3 (da) 2005-12-22 2006-12-04 Diagnostisk fremgangsmåde til genkendelse af bærere af Marburg I-varianten af den faktor VII-aktiverende protease (FSAP) ved differentiel modulering af FSAP-aktiviteten

Country Status (8)

Country Link
US (1) US7943333B2 (da)
EP (1) EP1801233B1 (da)
JP (1) JP4991273B2 (da)
AT (1) ATE446377T1 (da)
CA (1) CA2571660A1 (da)
DE (1) DE502006005169D1 (da)
DK (1) DK1801233T3 (da)
ES (1) ES2332467T3 (da)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2009011013A (ja) 2007-06-26 2009-01-15 Hitachi Ltd 電力変換装置
DE102007045099A1 (de) 2007-09-20 2008-10-30 Dade Behring Marburg Gmbh Verfahren zur Bestimmung eines Analyten mittels Ultraschall
AU2008318813A1 (en) * 2007-10-29 2009-05-07 Purdue Research Foundation Hybrid microfluidic SPR and molecular imaging device
EP2386652A1 (de) 2010-05-12 2011-11-16 Siemens Healthcare Diagnostics Products GmbH Homogenes Verfahren zur Bestimmung der Plasminogenaktivator-aktivierenden Aktivität der FSAP

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19903693A1 (de) 1998-04-24 1999-10-28 Centeon Pharma Gmbh Protease zur Aktivierung des Gerinnungsfaktors VII
DE10023923A1 (de) * 1999-06-10 2000-12-14 Aventis Behring Gmbh Verfahren zur Bestimmung der Aktivität der Faktor VII-aktivierenden Protease aus Proteinlösungen
ES2330544T3 (es) 2000-07-26 2009-12-11 Csl Behring Gmbh Mutantes de la proteasa activadora del factor vii y procedimientos de deteccion con anticuerpos especificos.
DE10238429A1 (de) * 2002-03-19 2003-10-30 Aventis Behring Gmbh Intellect Marburg I Mutante der Faktor VII aktivierenden Protease (FSAP) als Risikofaktor für Atherosklerose
DE50114021D1 (de) * 2001-01-08 2008-07-24 Csl Behring Gmbh Stabilisierte Flüssigzubereitung der den Blutgerinnungsfaktor VII aktivierenden Protease oder ihres Proenzyms
DE10205520A1 (de) * 2002-02-08 2003-08-14 Aventis Behring Gmbh Inhibitorischer, monoklonaler Antikörper gegen die den Blutgerinnungsfaktor VII aktivierende Protease
DE102005026163A1 (de) * 2004-08-24 2006-03-02 Dade Behring Marburg Gmbh Gegen den Marburg I Polymorphismus der Faktor VII aktivierenden Protease (FSAP) gerichtete Antikörper, ihre Herstellung und Verwendung

Also Published As

Publication number Publication date
US20070190574A1 (en) 2007-08-16
JP2007167069A (ja) 2007-07-05
EP1801233B1 (de) 2009-10-21
EP1801233A1 (de) 2007-06-27
CA2571660A1 (en) 2007-06-22
ES2332467T3 (es) 2010-02-05
JP4991273B2 (ja) 2012-08-01
DE502006005169D1 (de) 2009-12-03
ATE446377T1 (de) 2009-11-15
US7943333B2 (en) 2011-05-17

Similar Documents

Publication Publication Date Title
ATE556952T1 (de) Dichtungsanordnung
ATE415662T1 (de) Bestimmung der tatsächlichen zeit, die ein prozessor bei der ausführung eines codeteiles aufwendet
ATE541222T1 (de) Relative positionierung
MX2009013388A (es) Analisis multiple de muestras de sangre.
ATE497620T1 (de) Verfahren und vorrichtung zur erkennung von computerbetrug
DE602006007379D1 (de) Positionserfassungssystem mit selbstüberwachung für konnektivitätsfehler
ATE514755T1 (de) Fluoreszenzfarbstoffe zur verwendung bei der glukoseerfassung
EA200701510A1 (ru) Способ и устройство для оценки интервального времени пробега волны в пласте
TW200720441A (en) New labelling strategies for the sensitive detection of analytes
ATE512351T1 (de) Vorrichtung und verfahren zum aktualisieren von kartendaten
MA35212B1 (fr) Essai de la lysyl oxydase de type 2 et ses procédés d'utilisation
ATE493290T1 (de) Alcotestgerät
WO2014065889A3 (en) Multiplexed method for diagnosing classical hodgkin lymphoma
ATE456678T1 (de) Nukleinsäurenachweisverfahren mit erhöhter empfindlichkeit
DE502005008461D1 (de) Verfahren und laseranordnung mit einer vorrichtung zur zustandserkennung eines optischen elements
DE60328001D1 (de) Elektrochemische nachweissystemen
ATE495243T1 (de) Verfahren zur herstellung von hochempfindlichen endonukleasen, neuartige zubereitungen von nukleasen und ihre verwendung
TW200702981A (en) Exception analysis methods and systems
DK1801233T3 (da) Diagnostisk fremgangsmåde til genkendelse af bærere af Marburg I-varianten af den faktor VII-aktiverende protease (FSAP) ved differentiel modulering af FSAP-aktiviteten
ATE519116T1 (de) Verfahren zur normierung der konzentration von analyten in einer urinprobe
ATE474228T1 (de) Reagenz für hämoglobinabbau
WO2007037910A3 (en) Specific removal of activated immune cells
DE602007008080D1 (de) Detektion von zirkulierenden endothelzellen
WO2012030740A3 (en) Method for collecting and analyzing data from a flow cytometer
ATE406560T1 (de) Luftgestütztes verfahren zur detektion von landminen