DK175978B1 - Anvendelse af AICA-ribosid eller AICA-ribotid til fremstilling af et farmaceutisk præparat til behandling af hjerteanfald eller salgtilfælde i patienter, som lider af atherosklerose - Google Patents

Anvendelse af AICA-ribosid eller AICA-ribotid til fremstilling af et farmaceutisk præparat til behandling af hjerteanfald eller salgtilfælde i patienter, som lider af atherosklerose Download PDF

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Publication number
DK175978B1
DK175978B1 DK198901488A DK148889A DK175978B1 DK 175978 B1 DK175978 B1 DK 175978B1 DK 198901488 A DK198901488 A DK 198901488A DK 148889 A DK148889 A DK 148889A DK 175978 B1 DK175978 B1 DK 175978B1
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Prior art keywords
adenosine
aica
aica riboside
riboside
treatment
Prior art date
Application number
DK198901488A
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Danish (da)
English (en)
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DK148889D0 (da
DK148889A (da
Inventor
Harry Edward Gruber
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Univ California
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Publication of DK148889D0 publication Critical patent/DK148889D0/da
Publication of DK148889A publication Critical patent/DK148889A/da
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Publication of DK175978B1 publication Critical patent/DK175978B1/da

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/7056—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing five-membered rings with nitrogen as a ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/164—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • A61K38/166—Streptokinase
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/49—Urokinase; Tissue plasminogen activator
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/052—Imidazole radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/056—Triazole or tetrazole radicals

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Discharge Heating (AREA)
  • Re-Forming, After-Treatment, Cutting And Transporting Of Glass Products (AREA)
  • Examining Or Testing Airtightness (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DK198901488A 1987-07-29 1989-03-28 Anvendelse af AICA-ribosid eller AICA-ribotid til fremstilling af et farmaceutisk præparat til behandling af hjerteanfald eller salgtilfælde i patienter, som lider af atherosklerose DK175978B1 (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US07/079,657 US4912092A (en) 1986-03-27 1987-07-29 Methods for increasing extracellular adenosine and for stabilizing mast cells
US7965787 1987-07-29
PCT/US1988/002527 WO1989000854A1 (en) 1987-07-29 1988-07-29 Methods for increasing extracellular adenosine and for stabilizing mast cells
US8802527 1988-07-29

Publications (3)

Publication Number Publication Date
DK148889D0 DK148889D0 (da) 1989-03-28
DK148889A DK148889A (da) 1989-05-29
DK175978B1 true DK175978B1 (da) 2005-10-17

Family

ID=22151963

Family Applications (1)

Application Number Title Priority Date Filing Date
DK198901488A DK175978B1 (da) 1987-07-29 1989-03-28 Anvendelse af AICA-ribosid eller AICA-ribotid til fremstilling af et farmaceutisk præparat til behandling af hjerteanfald eller salgtilfælde i patienter, som lider af atherosklerose

Country Status (13)

Country Link
US (1) US4912092A (fi)
EP (2) EP0301900B1 (fi)
JP (1) JPH02500916A (fi)
AT (1) ATE135580T1 (fi)
AU (3) AU2315088A (fi)
BR (1) BR8807151A (fi)
CA (1) CA1335716C (fi)
DE (1) DE3855120T2 (fi)
DK (1) DK175978B1 (fi)
ES (1) ES2087061T3 (fi)
FI (1) FI891463A (fi)
GR (1) GR3019389T3 (fi)
WO (1) WO1989000854A1 (fi)

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US5654286A (en) * 1993-05-12 1997-08-05 Hostetler; Karl Y. Nucleotides for topical treatment of psoriasis, and methods for using same
US6342484B1 (en) 1993-06-30 2002-01-29 Board Of Regents, The University Of Texas Systems Method and compositions for promotion of wound treatment
WO1995001097A1 (en) * 1993-06-30 1995-01-12 Board Of Regents, The University Of Texas System Nucleotide preparation and uses thereof in wound healing
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US6800616B2 (en) 1998-02-26 2004-10-05 Supergen, Inc. Treatment of HIV infections
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US6680292B1 (en) 1998-11-20 2004-01-20 The Salk Institute For Biological Studies Pharmaceutical composition comprising ribavirin and growth factors and methods of use
AU2026900A (en) * 1998-11-20 2000-06-13 Salk Institute For Biological Studies, The Neuron stimulation by ribavirin, and analogs thereof
US6579857B1 (en) * 1999-06-11 2003-06-17 Evanston Northwestern Healthcare Research Institute Combination cancer therapy comprising adenosine and deaminase enzyme inhibitors
US6300328B1 (en) 1999-08-06 2001-10-09 Alcon Universal Ltd. Selective inhibitors of adenosine monophosphate deaminase for the treatment of optic nerve and retinal damage
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Also Published As

Publication number Publication date
AU687112B2 (en) 1998-02-19
AU1285592A (en) 1992-06-04
ATE135580T1 (de) 1996-04-15
DK148889D0 (da) 1989-03-28
AU2315088A (en) 1989-03-01
CA1335716C (en) 1995-05-30
GR3019389T3 (en) 1996-06-30
FI891463A0 (fi) 1989-03-28
EP0301900B1 (en) 1996-03-20
DE3855120T2 (de) 1996-09-19
EP0301900A3 (en) 1989-09-20
AU8039394A (en) 1995-03-09
EP0672418A3 (en) 1996-05-29
DE3855120D1 (de) 1996-04-25
WO1989000854A1 (en) 1989-02-09
DK148889A (da) 1989-05-29
JPH02500916A (ja) 1990-03-29
ES2087061T3 (es) 1996-07-16
BR8807151A (pt) 1989-10-17
EP0672418A2 (en) 1995-09-20
FI891463A (fi) 1989-03-28
EP0301900A2 (en) 1989-02-01
US4912092A (en) 1990-03-27

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