DK175889B1 - Sårheling og knogleregenerering - Google Patents

Sårheling og knogleregenerering Download PDF

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Publication number
DK175889B1
DK175889B1 DK198803932A DK393288A DK175889B1 DK 175889 B1 DK175889 B1 DK 175889B1 DK 198803932 A DK198803932 A DK 198803932A DK 393288 A DK393288 A DK 393288A DK 175889 B1 DK175889 B1 DK 175889B1
Authority
DK
Denmark
Prior art keywords
pdgf
igf
growth factor
platelet
purified
Prior art date
Application number
DK198803932A
Other languages
Danish (da)
English (en)
Other versions
DK393288D0 (da
DK393288A (da
Inventor
Harry N Antoniades
Ray C Williams
Samuel E Lynch
Original Assignee
Inst Molecular Biology Inc
Predident And Fellows Of Harva
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Inst Molecular Biology Inc, Predident And Fellows Of Harva filed Critical Inst Molecular Biology Inc
Publication of DK393288D0 publication Critical patent/DK393288D0/da
Publication of DK393288A publication Critical patent/DK393288A/da
Application granted granted Critical
Publication of DK175889B1 publication Critical patent/DK175889B1/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22Hormones
    • A61K38/28Insulins
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475Growth factors; Growth regulators
    • C07K14/49Platelet-derived growth factor [PDGF]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22Hormones
    • A61K38/27Growth hormone [GH], i.e. somatotropin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22Hormones
    • A61K38/30Insulin-like growth factors, i.e. somatomedins, e.g. IGF-1, IGF-2
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Endocrinology (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • Dermatology (AREA)
  • Toxicology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK198803932A 1986-11-14 1988-07-14 Sårheling og knogleregenerering DK175889B1 (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US93076286A 1986-11-14 1986-11-14
US93076286 1986-11-14
PCT/US1987/002975 WO1988003409A1 (en) 1986-11-14 1987-11-13 Wound healing and bone regeneration
US8702975 1987-11-13

Publications (3)

Publication Number Publication Date
DK393288D0 DK393288D0 (da) 1988-07-14
DK393288A DK393288A (da) 1988-09-13
DK175889B1 true DK175889B1 (da) 2005-05-30

Family

ID=25459724

Family Applications (1)

Application Number Title Priority Date Filing Date
DK198803932A DK175889B1 (da) 1986-11-14 1988-07-14 Sårheling og knogleregenerering

Country Status (15)

Country Link
EP (1) EP0289584B1 (ko)
JP (1) JPH01500199A (ko)
KR (1) KR960005708B1 (ko)
CN (1) CN1027346C (ko)
AT (1) ATE88899T1 (ko)
AU (1) AU600069B2 (ko)
DE (1) DE3785758T2 (ko)
DK (1) DK175889B1 (ko)
IE (1) IE60517B1 (ko)
MX (1) MX170454B (ko)
NO (1) NO883127L (ko)
NZ (1) NZ222551A (ko)
OA (1) OA09159A (ko)
WO (1) WO1988003409A1 (ko)
ZA (1) ZA878566B (ko)

Families Citing this family (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4849407A (en) * 1986-08-13 1989-07-18 Zymogenetics, Inc. Biologically active mosaic proteins
US5474982A (en) * 1986-08-13 1995-12-12 Zymogenetics, Inc. PDGF analogs and methods of use
US4885163A (en) * 1987-02-24 1989-12-05 Eli Lilly And Company Topical use of IGF-II for wound healing
IL95641A0 (en) * 1989-09-15 1991-06-30 Curative Tech Inc Preparation of a platelet releasate product
ZA9010332B (en) * 1989-12-22 1991-08-28 Ciba Geigy Method of reducing or preventing adverse effect of steroid therapy and compositions therefor
DE69031218T2 (de) * 1990-04-10 1997-12-11 Harvard College Wundheilung
JP3377524B2 (ja) * 1990-05-30 2003-02-17 プレジデント アンド フェロウズ オブ ハーバード カレッジ 創傷治癒
US6197325B1 (en) 1990-11-27 2001-03-06 The American National Red Cross Supplemented and unsupplemented tissue sealants, methods of their production and use
US6054122A (en) 1990-11-27 2000-04-25 The American National Red Cross Supplemented and unsupplemented tissue sealants, methods of their production and use
US6117425A (en) 1990-11-27 2000-09-12 The American National Red Cross Supplemented and unsupplemented tissue sealants, method of their production and use
US7229959B1 (en) 1990-11-27 2007-06-12 The American National Red Cross Supplemented fibrin matrix delivery systems
WO1993008825A1 (en) * 1991-11-04 1993-05-13 Zymogenetics, Inc. Pdgf gel formulation
FR2691911B1 (fr) * 1992-06-05 1994-11-25 Delmas Olivier Dispositif permettant l'obtention d'un surnageant de thrombocytes activés, procédé mettant en Óoeuvre le dispositif et surnageant obtenu.
JPH06510065A (ja) * 1992-06-08 1994-11-10 カイロン コーポレーション 成長因子igf−iおよび/またはigf−iiの用法
FR2696095B1 (fr) * 1992-09-30 1994-11-25 Inoteb Colle biologique à base de protéines coagulables par la thrombine, enrichie en facteurs plaquettaires, sa préparation et son application.
CN1055023C (zh) * 1993-01-03 2000-08-02 周至譓 伤口护理剂
US7026299B2 (en) 1994-07-12 2006-04-11 Human Genome Sciences, Inc. Connective tissue growth factor-2
AU689492B2 (en) 1994-07-12 1998-04-02 Human Genome Sciences, Inc. Connective tissue growth factor-2
US5712249A (en) * 1994-09-08 1998-01-27 Ciba-Geigy Corporation Use of insulin-like growth factors I and II for inhibition of inflammatory response
DE69637332T2 (de) 1995-10-11 2008-10-09 Novartis Vaccines and Diagnostics, Inc., Emeryville Kombinierung von PDGF, KGF, IGF und IGFBP für Wundheilung
JP4341859B2 (ja) 1996-12-13 2009-10-14 ノバルティス バクシンズ アンド ダイアグノスティックス, インコーポレーテッド 酵母での異種タンパク質の発現の方法
US6663870B2 (en) 1998-12-07 2003-12-16 Zymogenetics, Inc. Methods for promoting growth of bone using zvegf3
US6468543B1 (en) 1999-05-03 2002-10-22 Zymogenetics, Inc. Methods for promoting growth of bone using ZVEGF4
GB2369572A (en) 2000-11-29 2002-06-05 Raft Trustees Ltd Wound treatment composition comprising insulin
US7241874B2 (en) 2002-06-26 2007-07-10 Zimmer Ortho Biologics, Inc. Rapid isolation of osteoinductive protein mixtures from mammalian bone tissue
US7622562B2 (en) 2002-06-26 2009-11-24 Zimmer Orthobiologics, Inc. Rapid isolation of osteoinductive protein mixtures from mammalian bone tissue
US7473678B2 (en) 2004-10-14 2009-01-06 Biomimetic Therapeutics, Inc. Platelet-derived growth factor compositions and methods of use thereof
NZ571113A (en) 2005-11-17 2012-02-24 Biomimetic Therapeutics Inc Maxillofacial bone augmentation using rhpdgf-bb and a biocompatible matrix
EP2311505B1 (en) 2006-02-09 2013-11-06 BioMimetic Therapeutics, LLC Compositions and methods for treating bone
AU2007269712B2 (en) 2006-06-30 2013-02-07 Biomimetic Therapeutics, Llc PDGF-biomatrix compositions and methods for treating rotator cuff injuries
US9161967B2 (en) 2006-06-30 2015-10-20 Biomimetic Therapeutics, Llc Compositions and methods for treating the vertebral column
EP2462895B1 (en) 2006-11-03 2016-11-02 BioMimetic Therapeutics, LLC Compositions and methods for arthrodetic procedures
JP5864106B2 (ja) 2008-02-07 2016-02-17 バイオミメティック セラピューティクス, エルエルシー 仮骨延長のための組成物および方法
NZ602861A (en) 2008-09-09 2014-03-28 Biomimetic Therapeutics Llc Platelet-derived growth factor compositions and methods for the treatment of tendon and ligament injuries
AU2011217784B2 (en) 2010-02-22 2014-10-09 Biomimetic Therapeutics, Llc. Platelet-derived growth factor compositions and methods for the treatment of tendinopathies
CN102397534B (zh) * 2010-09-07 2013-10-23 中国人民解放军总医院 胰岛素在制备促进颌骨组织愈合的药物中的用途
WO2013077641A1 (ko) * 2011-11-22 2013-05-30 (주)아모레퍼시픽 성장 인자를 포함하는 피부 재생 촉진제
JP6871855B2 (ja) 2014-10-14 2021-05-19 サムエル リンチ, 創傷を処置するための組成物

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4479896A (en) * 1981-12-11 1984-10-30 Antoniades Harry N Method for extraction localization and direct recovery of platelet derived growth factor

Also Published As

Publication number Publication date
DE3785758T2 (de) 1993-08-05
ATE88899T1 (de) 1993-05-15
EP0289584A1 (en) 1988-11-09
IE873075L (en) 1988-05-14
EP0289584B1 (en) 1993-05-05
WO1988003409A1 (en) 1988-05-19
OA09159A (en) 1992-03-31
KR960005708B1 (ko) 1996-05-01
JPH0581569B2 (ko) 1993-11-15
CN1027346C (zh) 1995-01-11
EP0289584A4 (en) 1990-01-08
MX170454B (es) 1993-08-24
DK393288D0 (da) 1988-07-14
DE3785758D1 (de) 1993-06-09
AU600069B2 (en) 1990-08-02
NO883127D0 (no) 1988-07-13
CN87101250A (zh) 1988-06-08
DK393288A (da) 1988-09-13
IE60517B1 (en) 1994-07-27
ZA878566B (en) 1989-07-26
NO883127L (no) 1988-09-12
KR890700033A (ko) 1989-03-02
NZ222551A (en) 1989-11-28
AU8328987A (en) 1988-06-01
JPH01500199A (ja) 1989-01-26

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