DK1756049T3 - Fremgangsmåde til fremstilling af 1,4-diphenylazetidinon-derivater - Google Patents

Fremgangsmåde til fremstilling af 1,4-diphenylazetidinon-derivater

Info

Publication number
DK1756049T3
DK1756049T3 DK05747892T DK05747892T DK1756049T3 DK 1756049 T3 DK1756049 T3 DK 1756049T3 DK 05747892 T DK05747892 T DK 05747892T DK 05747892 T DK05747892 T DK 05747892T DK 1756049 T3 DK1756049 T3 DK 1756049T3
Authority
DK
Denmark
Prior art keywords
preparation
diphenylazetidinone derivatives
diphenylazetidinone
derivatives
Prior art date
Application number
DK05747892T
Other languages
Danish (da)
English (en)
Inventor
Andreas Lindenschmidt
Gerhard Jaehne
Wendelin Frick
Bernd Junker
Guenter Billen
Heiner Jendralla
Theodor Andreas Wollmann
David William Will
David Rigal
Original Assignee
Sanofi Aventis Deutschland
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE200410025071 external-priority patent/DE102004025071B4/de
Priority claimed from DE102005010770A external-priority patent/DE102005010770A1/de
Application filed by Sanofi Aventis Deutschland filed Critical Sanofi Aventis Deutschland
Application granted granted Critical
Publication of DK1756049T3 publication Critical patent/DK1756049T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D205/00Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Obesity (AREA)
  • Engineering & Computer Science (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Catalysts (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK05747892T 2004-05-21 2005-05-20 Fremgangsmåde til fremstilling af 1,4-diphenylazetidinon-derivater DK1756049T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE200410025071 DE102004025071B4 (de) 2004-05-21 2004-05-21 Verfahren zur Herstellung von Diphenylazetidinon-Derivaten
DE102005010770A DE102005010770A1 (de) 2005-03-09 2005-03-09 Verfahren zur Herstellung von 1,4-Diphenylazetidinon-Derivaten
PCT/EP2005/005498 WO2005113496A1 (de) 2004-05-21 2005-05-20 Verfahren zur herstellung von 1,4-diphenylazetidinon-derivaten

Publications (1)

Publication Number Publication Date
DK1756049T3 true DK1756049T3 (da) 2008-02-25

Family

ID=37561403

Family Applications (1)

Application Number Title Priority Date Filing Date
DK05747892T DK1756049T3 (da) 2004-05-21 2005-05-20 Fremgangsmåde til fremstilling af 1,4-diphenylazetidinon-derivater

Country Status (26)

Country Link
US (1) US7488818B2 (ko)
EP (1) EP1756049B1 (ko)
JP (1) JP2007538042A (ko)
KR (1) KR20070027554A (ko)
AR (1) AR049184A1 (ko)
AT (1) ATE376997T1 (ko)
AU (1) AU2005245124A1 (ko)
BR (1) BRPI0510150A (ko)
CA (1) CA2567149A1 (ko)
CY (1) CY1107425T1 (ko)
DE (1) DE502005001841D1 (ko)
DK (1) DK1756049T3 (ko)
ES (1) ES2294712T3 (ko)
HK (1) HK1103296A1 (ko)
HR (1) HRP20070570T3 (ko)
IL (1) IL178991A0 (ko)
MA (1) MA28635B1 (ko)
MX (1) MXPA06013456A (ko)
NZ (1) NZ551413A (ko)
PL (1) PL1756049T3 (ko)
PT (1) PT1756049E (ko)
RS (1) RS50539B (ko)
RU (1) RU2380361C2 (ko)
TW (1) TW200611896A (ko)
UY (1) UY28912A1 (ko)
WO (1) WO2005113496A1 (ko)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0215579D0 (en) 2002-07-05 2002-08-14 Astrazeneca Ab Chemical compounds
ATE485267T1 (de) 2003-12-23 2010-11-15 Astrazeneca Ab Diphenylazetidinonderivate mit die cholesterinabsorption hemmender wirkung
CA2550373C (en) * 2003-12-23 2012-01-31 Merck & Co., Inc. Anti-hypercholesterolemic compounds
UY29607A1 (es) 2005-06-20 2007-01-31 Astrazeneca Ab Compuestos quimicos
SA06270191B1 (ar) 2005-06-22 2010-03-29 استرازينيكا ايه بي مشتقات من 2- أزيتيدينون جديدة باعتبارها مثبطات لامتصاص الكوليسترول لعلاج حالات فرط نسبة الدهون في الدم
MY148538A (en) 2005-06-22 2013-04-30 Astrazeneca Ab Novel 2-azetidinone derivatives as cholesterol absorption inhibitors for the treatment of hyperlipidaemic conditions
AR060623A1 (es) 2006-04-27 2008-07-02 Astrazeneca Ab Compuestos derivados de 2-azetidinona y un metodo de preparacion
US20090047716A1 (en) * 2007-06-07 2009-02-19 Nurit Perlman Reduction processes for the preparation of ezetimibe
EP2414529A2 (en) 2009-04-01 2012-02-08 Matrix Laboratories Ltd Enzymatic process for the preparation of (s)-5-(4-fluoro-phenyl)-5-hydroxy- 1morpholin-4-yl-pentan-1-one, an intermediate of ezetimibe and further conversion to ezetimibe
WO2011056895A1 (en) * 2009-11-03 2011-05-12 University Of Notre Dame Du Lac Ionic liquids comprising heteraromatic anions
EP2567959B1 (en) 2011-09-12 2014-04-16 Sanofi 6-(4-hydroxy-phenyl)-3-styryl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors
US9670237B2 (en) 2011-09-22 2017-06-06 Ut-Battelle, Llc Phosphonium-based ionic liquids and their use in the capture of polluting gases
US10385251B2 (en) 2013-09-30 2019-08-20 University Of Notre Dame Du Lac Compounds, complexes, compositions, methods and systems for heating and cooling
US10086331B2 (en) 2013-11-05 2018-10-02 University Of Notre Dame Du Lac Carbon dioxide capture using phase change ionic liquids
JP6803138B2 (ja) * 2014-10-22 2020-12-23 三星エスディアイ株式会社Samsung SDI Co., Ltd. ホスホニウム系化合物、それを含むエポキシ樹脂組成物、およびそれを用いて製造された半導体装置

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0596015B1 (en) * 1991-07-23 1997-10-01 Schering Corporation Substituted beta-lactam compounds useful as hypocholesterolemic agents and processes for the preparation thereof
WO1995001961A1 (en) * 1993-07-09 1995-01-19 Schering Corporation Process for the synthesis of azetidinones
US5631365A (en) * 1993-09-21 1997-05-20 Schering Corporation Hydroxy-substituted azetidinone compounds useful as hypocholesterolemic agents
HUP0401081A3 (en) * 2000-12-21 2010-06-28 Sanofi Aventis Deutschland Novel 1,2-diphenzylazetidinones, method for producing the same, medicaments containing said compounds, and their use
TWI291957B (en) * 2001-02-23 2008-01-01 Kotobuki Pharmaceutical Co Ltd Beta-lactam compounds, process for repoducing the same and serum cholesterol-lowering agents containing the same

Also Published As

Publication number Publication date
CY1107425T1 (el) 2013-03-13
EP1756049A1 (de) 2007-02-28
ATE376997T1 (de) 2007-11-15
PL1756049T3 (pl) 2008-02-29
US7488818B2 (en) 2009-02-10
BRPI0510150A (pt) 2007-10-02
PT1756049E (pt) 2007-12-17
AR049184A1 (es) 2006-07-05
ES2294712T3 (es) 2008-04-01
WO2005113496A1 (de) 2005-12-01
KR20070027554A (ko) 2007-03-09
CA2567149A1 (en) 2005-12-01
HK1103296A1 (en) 2007-12-14
AU2005245124A1 (en) 2005-12-01
UY28912A1 (es) 2005-12-30
TW200611896A (en) 2006-04-16
JP2007538042A (ja) 2007-12-27
MA28635B1 (fr) 2007-06-01
RS50539B (sr) 2010-05-07
IL178991A0 (en) 2007-03-08
RU2006145444A (ru) 2008-06-27
DE502005001841D1 (de) 2007-12-13
US20070149776A1 (en) 2007-06-28
NZ551413A (en) 2009-07-31
HRP20070570T3 (en) 2008-01-31
MXPA06013456A (es) 2007-03-01
EP1756049B1 (de) 2007-10-31
RU2380361C2 (ru) 2010-01-27

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