DK175094B1 - Anvendelse af N-butyl-derivatet af deoxynojirimycin til fremstilling af farmaceutisk præparat - Google Patents

Anvendelse af N-butyl-derivatet af deoxynojirimycin til fremstilling af farmaceutisk præparat Download PDF

Info

Publication number
DK175094B1
DK175094B1 DK198807079A DK707988A DK175094B1 DK 175094 B1 DK175094 B1 DK 175094B1 DK 198807079 A DK198807079 A DK 198807079A DK 707988 A DK707988 A DK 707988A DK 175094 B1 DK175094 B1 DK 175094B1
Authority
DK
Denmark
Prior art keywords
hiv
cells
deoxynojirimycin
dnj
butyl
Prior art date
Application number
DK198807079A
Other languages
Danish (da)
English (en)
Other versions
DK707988D0 (da
DK707988A (da
Inventor
Raymond Allen Dwek
George William John Fleet
Thomas William Rademacher
Original Assignee
Monsanto Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US07/248,461 external-priority patent/US4849430A/en
Application filed by Monsanto Co filed Critical Monsanto Co
Publication of DK707988D0 publication Critical patent/DK707988D0/da
Publication of DK707988A publication Critical patent/DK707988A/da
Application granted granted Critical
Publication of DK175094B1 publication Critical patent/DK175094B1/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Transplantation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Saccharide Compounds (AREA)
DK198807079A 1987-12-21 1988-12-20 Anvendelse af N-butyl-derivatet af deoxynojirimycin til fremstilling af farmaceutisk præparat DK175094B1 (da)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US13622487A 1987-12-21 1987-12-21
US13622487 1987-12-21
US16606588A 1988-03-09 1988-03-09
US16606588 1988-03-09
US07/248,461 US4849430A (en) 1988-03-09 1988-09-23 Method of inhibiting virus
US24846188 1988-09-23

Publications (3)

Publication Number Publication Date
DK707988D0 DK707988D0 (da) 1988-12-20
DK707988A DK707988A (da) 1989-06-22
DK175094B1 true DK175094B1 (da) 2004-06-01

Family

ID=27384837

Family Applications (1)

Application Number Title Priority Date Filing Date
DK198807079A DK175094B1 (da) 1987-12-21 1988-12-20 Anvendelse af N-butyl-derivatet af deoxynojirimycin til fremstilling af farmaceutisk præparat

Country Status (15)

Country Link
EP (1) EP0324328B1 (xx)
JP (1) JPH01203326A (xx)
KR (1) KR910010020B1 (xx)
AT (1) ATE159427T1 (xx)
AU (1) AU605661B2 (xx)
CA (1) CA1316459C (xx)
DE (1) DE3856052T2 (xx)
DK (1) DK175094B1 (xx)
ES (1) ES2108680T3 (xx)
GR (1) GR3025518T3 (xx)
IE (1) IE81173B1 (xx)
IL (1) IL88740A (xx)
NZ (1) NZ227411A (xx)
OA (1) OA09027A (xx)
PT (1) PT89266B (xx)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA883925B (en) * 1987-06-08 1989-02-22 Merrell Dow Pharma Inhibitors of glycoprotein processing having anti-retroviral activity
US5144037A (en) * 1988-11-03 1992-09-01 G. D. Searle & Co. 1,5-dideoxy-1,5-imino-d-glucitol derivatives
US20030100532A1 (en) 1997-02-14 2003-05-29 Gary S. Jacob Use of n-substituted-1,5-dideoxy-1,5-imino-d-glucitol compounds in combination therapy for treating hepatitis virus infections
EP1030839B1 (en) * 1997-11-10 2004-02-04 G.D. SEARLE & CO. Use of alkylated iminosugars to treat multidrug resistance
KR20010040937A (ko) 1998-02-12 2001-05-15 윌리암스 로저 에이 간염 바이러스 감염의 치료를 위한 n-치환된1,5-디데옥시-1,5-이미노-d-글루시톨 화합물의 용도
US6689759B1 (en) 1998-02-12 2004-02-10 G. D. Searle & Co. Methods of Treating hepatitis virus infections with N-substituted-1,5-dideoxy-1,5-imino-d-glucitol compounds in combination therapy
JP2003505501A (ja) 1999-02-12 2003-02-12 ジー・ディー・サール・アンド・カンパニー 肝炎ウィルス感染の処置のためのグルカミン化合物
US6545021B1 (en) 1999-02-12 2003-04-08 G.D. Searle & Co. Use of substituted-1,5-dideoxy-1,5-imino-D-glucitol compounds for treating hepatitis virus infections
KR20090040906A (ko) * 2006-08-02 2009-04-27 유나이티드 세러퓨틱스 코오포레이션 바이러스 감염의 리포솜 치료
CN115806913B (zh) * 2022-10-21 2023-09-08 福建省农业科学院植物保护研究所 野尻链霉菌(Streptomyces nojiriensis)菌株9-13及应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4065562A (en) * 1975-12-29 1977-12-27 Nippon Shinyaku Co., Ltd. Method and composition for reducing blood glucose levels
JPS5311800A (en) * 1976-07-20 1978-02-02 Asahi Chemical Ind Method of well preserving and transporting live fish and apparatus therefor
NO154918C (no) * 1977-08-27 1987-01-14 Bayer Ag Analogifremgangsmaate til fremstilling av terapeutisk aktive derivater av 3,4,5-trihydroksypiperidin.
DE3737523A1 (de) * 1987-11-05 1989-05-18 Bayer Ag Verwendung von substituierten hydroxypiperidinen als antivirale mittel

Also Published As

Publication number Publication date
NZ227411A (en) 1997-03-24
KR890009401A (ko) 1989-08-01
ATE159427T1 (de) 1997-11-15
JPH01203326A (ja) 1989-08-16
GR3025518T3 (en) 1998-02-27
CA1316459C (en) 1993-04-20
AU605661B2 (en) 1991-01-17
DK707988D0 (da) 1988-12-20
IE883793L (en) 1989-06-21
OA09027A (fr) 1991-03-31
EP0324328B1 (en) 1997-10-22
IL88740A (en) 1993-01-31
PT89266A (pt) 1989-12-29
IE81173B1 (en) 2000-05-31
EP0324328A3 (en) 1990-06-20
KR910010020B1 (ko) 1991-12-10
EP0324328A2 (en) 1989-07-19
PT89266B (pt) 1993-11-30
AU2706788A (en) 1989-06-22
DE3856052D1 (de) 1997-11-27
DE3856052T2 (de) 1998-02-19
JPH0521891B2 (xx) 1993-03-25
ES2108680T3 (es) 1998-01-01
IL88740A0 (en) 1989-07-31
DK707988A (da) 1989-06-22

Similar Documents

Publication Publication Date Title
US4849430A (en) Method of inhibiting virus
US5736527A (en) Method of treating HIV in humans by administration of ddI and hydroxycarbamide
Lin et al. Selective inhibition of human immunodeficiency virus type 1 replication by the (-) but not the (+) enantiomer of gossypol
KR0180019B1 (ko) 개량된 화학적 화합물
Montefiori et al. Role of protein N-glycosylation in pathogenesis of human immunodeficiency virus type 1.
EP0252962B1 (en) Regulating retroviral replication, infection, and pathogenesis
US6046228A (en) Anti-viral pharmaceutical compositions containing saturated 1,2-dithiaheterocyclic compounds and uses thereof
DK175094B1 (da) Anvendelse af N-butyl-derivatet af deoxynojirimycin til fremstilling af farmaceutisk præparat
WO1996022777A1 (en) Mixtures of dideoxy-nucleosides and hydroxycarbamide for inhibiting retroviral spread
EA015132B1 (ru) Лекарственное средство для лечения вирусных инфекций
EP0295538A2 (en) Inhibitors of glycoprotein processing having anti retroviral activity
Ruprecht et al. Castanospermine vs. its 6-O-butanoyl analog: a comparison of toxicity and antiviral activity in vitro and in vivo
US5519028A (en) Antiviral preparations
Ruprecht Murine models for antiretroviral therapy
Wainberg et al. Vaccine and antiviral strategies against infections caused by human immunodeficiency virus.
Sinet et al. Factors influencing zidovudine efficacy when administered at early stages of Friend virus infection in mice
US7220437B2 (en) Antiviral and antibacterial activities of extracts from eight plants
WO1992007564A2 (en) Method of treating demyelinating disease
AU718325B2 (en) Mixtures of dideoxy-nucleosides and hydroxycarbamide for inhibiting retroviral spread
CZ38997A3 (en) Combination of hiv-protease inhibitors and pharmaceutical preparation
US20050085441A1 (en) Use of soluble monovalent oligosaccharides as inhibitors of HIV-1 fusion and replication
Bland Sudden death while on phenothiazines
US20040077590A1 (en) Use of soluble monovalent oligosaccharides as inhibitors of HIV-1 fusion and replication
CA2374198A1 (en) Combination therapy for treatment of fiv infection
WO1995017875A2 (en) MIXTURES OF DIDEOXYNUCLEOSIDES AND D-ASPARTIC ACID β-HYDROXAMATE FOR INHIBITING RETROVIRAL SPREAD

Legal Events

Date Code Title Description
PBP Patent lapsed

Country of ref document: DK