DK1730144T3 - Substituerede 1,4,8-triazaspiro[4.5]decan-2-on-forbindelser - Google Patents
Substituerede 1,4,8-triazaspiro[4.5]decan-2-on-forbindelserInfo
- Publication number
- DK1730144T3 DK1730144T3 DK05716300T DK05716300T DK1730144T3 DK 1730144 T3 DK1730144 T3 DK 1730144T3 DK 05716300 T DK05716300 T DK 05716300T DK 05716300 T DK05716300 T DK 05716300T DK 1730144 T3 DK1730144 T3 DK 1730144T3
- Authority
- DK
- Denmark
- Prior art keywords
- compounds
- triazaspiro
- decan
- substituted
- novel
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/10—Spiro-condensed systems
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P11/02—Nasal agents, e.g. decongestants
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P11/06—Antiasthmatics
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P13/12—Drugs for disorders of the urinary system of the kidneys
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61P17/06—Antipsoriatics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
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- A—HUMAN NECESSITIES
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- A61P19/06—Antigout agents, e.g. antihyperuricemic or uricosuric agents
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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- A61P25/32—Alcohol-abuse
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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- A—HUMAN NECESSITIES
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- A61P3/00—Drugs for disorders of the metabolism
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- A—HUMAN NECESSITIES
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- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61P37/00—Drugs for immunological or allergic disorders
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- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
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- A—HUMAN NECESSITIES
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- A61P37/08—Antiallergic agents
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/14—Drugs for disorders of the endocrine system of the thyroid hormones, e.g. T3, T4
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Immunology (AREA)
- Diabetes (AREA)
- Psychiatry (AREA)
- Hematology (AREA)
- Rheumatology (AREA)
- Physical Education & Sports Medicine (AREA)
- Pulmonology (AREA)
- Addiction (AREA)
- Pain & Pain Management (AREA)
- Dermatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Endocrinology (AREA)
- Ophthalmology & Optometry (AREA)
- Obesity (AREA)
- Anesthesiology (AREA)
- Psychology (AREA)
- Heart & Thoracic Surgery (AREA)
- Urology & Nephrology (AREA)
- Oncology (AREA)
- Cardiology (AREA)
- Child & Adolescent Psychology (AREA)
- Otolaryngology (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE102004014304A DE102004014304A1 (de) | 2004-03-22 | 2004-03-22 | Substituierte 1,4,8- Triazaspiro[4,5]decan-2-on-Verbindungen |
| PCT/EP2005/003051 WO2005095398A1 (de) | 2004-03-22 | 2005-03-22 | Substituierte 1,4,8-triazaspiro[4.5]decan-2-on-verbindungen |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1730144T3 true DK1730144T3 (da) | 2009-10-12 |
Family
ID=34961965
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK05716300T DK1730144T3 (da) | 2004-03-22 | 2005-03-22 | Substituerede 1,4,8-triazaspiro[4.5]decan-2-on-forbindelser |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US7560468B2 (da) |
| EP (1) | EP1730144B1 (da) |
| JP (1) | JP5148997B2 (da) |
| AT (1) | ATE433450T1 (da) |
| CA (1) | CA2560684A1 (da) |
| CY (1) | CY1109366T1 (da) |
| DE (2) | DE102004014304A1 (da) |
| DK (1) | DK1730144T3 (da) |
| ES (1) | ES2328496T3 (da) |
| PL (1) | PL1730144T3 (da) |
| PT (1) | PT1730144E (da) |
| SI (1) | SI1730144T1 (da) |
| WO (1) | WO2005095398A1 (da) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8124613B2 (en) * | 2006-06-14 | 2012-02-28 | Virochem Pharma Inc. | Spirotropane compounds |
| US8653068B2 (en) | 2009-10-30 | 2014-02-18 | Pain Therapeutics, Inc. | Filamin A binding anti-inflammatory and analgesic |
| US9340558B2 (en) | 2007-11-02 | 2016-05-17 | Pain Therapeutics Inc. | Filamin a binding anti-inflammatory and analgesic |
| US8614324B2 (en) * | 2008-10-31 | 2013-12-24 | Pain Therapeutics, Inc. | Filamin A binding anti-inflammatory and analgesic |
| US8580808B2 (en) * | 2009-10-30 | 2013-11-12 | Pain Therapeutic, Inc. | Filamin A-binding anti-inflammatory analgesic |
| EP2498600B1 (en) * | 2008-10-31 | 2016-03-02 | Pain Therapeutics, Inc. | Filamin a-binding anti-inflammatory analgesic |
| AU2009308702B2 (en) * | 2008-10-31 | 2015-05-28 | Pain Therapeutics, Inc. | Filamin A binding anti-inflammatory and analgesic |
| US8580809B2 (en) * | 2009-10-30 | 2013-11-12 | Pain Therapeutics, Inc. | Filamin A-binding anti-inflammatory analgesic |
| ES2716049T3 (es) | 2012-07-13 | 2019-06-07 | Pain Therapeutics Inc | Un método para inhibir la fosforilación de tau |
| EP2872899B1 (en) | 2012-07-13 | 2018-07-11 | Pain Therapeutics, Inc. | Alzheimer's disease assay in a living patient |
| US9433604B2 (en) * | 2013-10-08 | 2016-09-06 | Pain Therapeutics Inc. | Method for inhibiting growth of cancer cells |
| CA3131146A1 (en) | 2019-02-21 | 2020-08-27 | Pain Therapeutics, Inc. | Solid polymorphs of a flna-binding compound and its hydrochloride salts |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3725389A (en) * | 1971-07-02 | 1973-04-03 | American Home Prod | Adducts of delta-aminobenzylpenicillin and n-substituted-4-piperidones |
| JP2575446B2 (ja) * | 1988-02-12 | 1997-01-22 | 武田薬品工業株式会社 | トリアザスピロ化合物 |
| TW251284B (da) * | 1992-11-02 | 1995-07-11 | Pfizer | |
| WO1994021619A1 (en) * | 1993-03-16 | 1994-09-29 | Pfizer Inc. | Naphthalene derivatives |
| AU1682400A (en) * | 1998-12-09 | 2000-06-26 | Banyu Pharmaceutical Co., Ltd. | 4-oxoimidazolidine-2-spiro-nitrogenous heterocycle compounds |
| WO2001096337A1 (fr) * | 2000-06-14 | 2001-12-20 | Banyu Pharmaceutical Co.,Ltd | Composes heterocycliques 4-oxoimidazolidine-2-spiro-azotes |
| US7192964B2 (en) * | 2001-07-23 | 2007-03-20 | Banyu Pharmaceutical Co., Ltd. | 4-oxoimidazolidine-2-spiropiperidine derivatives |
-
2004
- 2004-03-22 DE DE102004014304A patent/DE102004014304A1/de not_active Withdrawn
-
2005
- 2005-03-22 SI SI200530775T patent/SI1730144T1/sl unknown
- 2005-03-22 AT AT05716300T patent/ATE433450T1/de active
- 2005-03-22 CA CA002560684A patent/CA2560684A1/en not_active Abandoned
- 2005-03-22 ES ES05716300T patent/ES2328496T3/es active Active
- 2005-03-22 PT PT05716300T patent/PT1730144E/pt unknown
- 2005-03-22 EP EP05716300A patent/EP1730144B1/de active Active
- 2005-03-22 DE DE502005007459T patent/DE502005007459D1/de active Active
- 2005-03-22 DK DK05716300T patent/DK1730144T3/da active
- 2005-03-22 WO PCT/EP2005/003051 patent/WO2005095398A1/de active Application Filing
- 2005-03-22 JP JP2007504345A patent/JP5148997B2/ja not_active Expired - Fee Related
- 2005-03-22 PL PL05716300T patent/PL1730144T3/pl unknown
-
2006
- 2006-09-22 US US11/525,052 patent/US7560468B2/en not_active Expired - Fee Related
-
2009
- 2009-09-08 CY CY20091100935T patent/CY1109366T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| PT1730144E (pt) | 2009-09-14 |
| DE502005007459D1 (de) | 2009-07-23 |
| CY1109366T1 (el) | 2014-07-02 |
| ES2328496T3 (es) | 2009-11-13 |
| EP1730144A1 (de) | 2006-12-13 |
| JP2007529568A (ja) | 2007-10-25 |
| JP5148997B2 (ja) | 2013-02-20 |
| US7560468B2 (en) | 2009-07-14 |
| CA2560684A1 (en) | 2005-10-13 |
| DE102004014304A1 (de) | 2005-10-06 |
| EP1730144B1 (de) | 2009-06-10 |
| US20070015783A1 (en) | 2007-01-18 |
| PL1730144T3 (pl) | 2009-11-30 |
| SI1730144T1 (sl) | 2009-12-31 |
| WO2005095398A1 (de) | 2005-10-13 |
| ATE433450T1 (de) | 2009-06-15 |
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