PT1730144E - Compostos de 1,4,8-triaza-espiro[4.5]decan-2-ona substituídos - Google Patents

Compostos de 1,4,8-triaza-espiro[4.5]decan-2-ona substituídos Download PDF

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Publication number
PT1730144E
PT1730144E PT05716300T PT05716300T PT1730144E PT 1730144 E PT1730144 E PT 1730144E PT 05716300 T PT05716300 T PT 05716300T PT 05716300 T PT05716300 T PT 05716300T PT 1730144 E PT1730144 E PT 1730144E
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PT
Portugal
Prior art keywords
compounds
triazaspiro
decan
substituted
novel
Prior art date
Application number
PT05716300T
Other languages
English (en)
Inventor
Hagen-Heinrich Hennies
Werner Englberger
Stefan Oberboersch
Bernd Sundermann
Corinna Sundermann
Original Assignee
Gruenenthal Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gruenenthal Gmbh filed Critical Gruenenthal Gmbh
Publication of PT1730144E publication Critical patent/PT1730144E/pt

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/10Spiro-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/02Nasal agents, e.g. decongestants
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    • A61P11/00Drugs for disorders of the respiratory system
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    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
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    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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    • A61P35/00Antineoplastic agents
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    • A61P37/02Immunomodulators
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    • A61P5/14Drugs for disorders of the endocrine system of the thyroid hormones, e.g. T3, T4
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    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P9/00Drugs for disorders of the cardiovascular system
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

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  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Diabetes (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Hematology (AREA)
  • Psychiatry (AREA)
  • Rheumatology (AREA)
  • Pulmonology (AREA)
  • Pain & Pain Management (AREA)
  • Addiction (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Ophthalmology & Optometry (AREA)
  • Obesity (AREA)
  • Dermatology (AREA)
  • Endocrinology (AREA)
  • Psychology (AREA)
  • Anesthesiology (AREA)
  • Urology & Nephrology (AREA)
  • Oncology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Otolaryngology (AREA)
  • Reproductive Health (AREA)
PT05716300T 2004-03-22 2005-03-22 Compostos de 1,4,8-triaza-espiro[4.5]decan-2-ona substituídos PT1730144E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE102004014304A DE102004014304A1 (de) 2004-03-22 2004-03-22 Substituierte 1,4,8- Triazaspiro[4,5]decan-2-on-Verbindungen

Publications (1)

Publication Number Publication Date
PT1730144E true PT1730144E (pt) 2009-09-14

Family

ID=34961965

Family Applications (1)

Application Number Title Priority Date Filing Date
PT05716300T PT1730144E (pt) 2004-03-22 2005-03-22 Compostos de 1,4,8-triaza-espiro[4.5]decan-2-ona substituídos

Country Status (13)

Country Link
US (1) US7560468B2 (pt)
EP (1) EP1730144B1 (pt)
JP (1) JP5148997B2 (pt)
AT (1) ATE433450T1 (pt)
CA (1) CA2560684A1 (pt)
CY (1) CY1109366T1 (pt)
DE (2) DE102004014304A1 (pt)
DK (1) DK1730144T3 (pt)
ES (1) ES2328496T3 (pt)
PL (1) PL1730144T3 (pt)
PT (1) PT1730144E (pt)
SI (1) SI1730144T1 (pt)
WO (1) WO2005095398A1 (pt)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2655203A1 (en) * 2006-06-14 2007-12-21 Virochem Pharma Inc. Spirotropane compounds
US9340558B2 (en) 2007-11-02 2016-05-17 Pain Therapeutics Inc. Filamin a binding anti-inflammatory and analgesic
US8614324B2 (en) * 2008-10-31 2013-12-24 Pain Therapeutics, Inc. Filamin A binding anti-inflammatory and analgesic
US8653068B2 (en) 2009-10-30 2014-02-18 Pain Therapeutics, Inc. Filamin A binding anti-inflammatory and analgesic
US8580808B2 (en) * 2009-10-30 2013-11-12 Pain Therapeutic, Inc. Filamin A-binding anti-inflammatory analgesic
CA2779252C (en) * 2008-10-31 2015-05-05 Pain Therapeutics, Inc. Filamin a-binding anti-inflammatory analgesic
EP2488177B1 (en) * 2008-10-31 2016-10-12 Pain Therapeutics, Inc. Filamin a binding anti-inflammatory and analgesic
US8580809B2 (en) * 2009-10-30 2013-11-12 Pain Therapeutics, Inc. Filamin A-binding anti-inflammatory analgesic
EP2872899B1 (en) 2012-07-13 2018-07-11 Pain Therapeutics, Inc. Alzheimer's disease assay in a living patient
WO2014011917A2 (en) 2012-07-13 2014-01-16 Pain Therapeutics, Inc. A method of inhibiting tau phosphorylation
US9433604B2 (en) * 2013-10-08 2016-09-06 Pain Therapeutics Inc. Method for inhibiting growth of cancer cells
BR112021016622A2 (pt) * 2019-02-21 2021-11-03 Pain Therapeutics Inc Polimorfos sólidos de um composto de ligação de flna e seus sais de cloridrato

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3725389A (en) * 1971-07-02 1973-04-03 American Home Prod Adducts of delta-aminobenzylpenicillin and n-substituted-4-piperidones
JP2575446B2 (ja) * 1988-02-12 1997-01-22 武田薬品工業株式会社 トリアザスピロ化合物
TW251284B (pt) * 1992-11-02 1995-07-11 Pfizer
DE69427289T2 (de) * 1993-03-16 2001-09-06 Pfizer Inc., New York Naphtalinderivate
AU1682400A (en) * 1998-12-09 2000-06-26 Banyu Pharmaceutical Co., Ltd. 4-oxoimidazolidine-2-spiro-nitrogenous heterocycle compounds
WO2001096337A1 (fr) * 2000-06-14 2001-12-20 Banyu Pharmaceutical Co.,Ltd Composes heterocycliques 4-oxoimidazolidine-2-spiro-azotes
US7192964B2 (en) * 2001-07-23 2007-03-20 Banyu Pharmaceutical Co., Ltd. 4-oxoimidazolidine-2-spiropiperidine derivatives

Also Published As

Publication number Publication date
JP2007529568A (ja) 2007-10-25
PL1730144T3 (pl) 2009-11-30
WO2005095398A1 (de) 2005-10-13
JP5148997B2 (ja) 2013-02-20
SI1730144T1 (sl) 2009-12-31
US7560468B2 (en) 2009-07-14
EP1730144A1 (de) 2006-12-13
CA2560684A1 (en) 2005-10-13
DE102004014304A1 (de) 2005-10-06
DE502005007459D1 (de) 2009-07-23
ES2328496T3 (es) 2009-11-13
US20070015783A1 (en) 2007-01-18
CY1109366T1 (el) 2014-07-02
EP1730144B1 (de) 2009-06-10
ATE433450T1 (de) 2009-06-15
DK1730144T3 (da) 2009-10-12

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