DK1725552T3 - Nye kvaterniserede quinuclidinestere - Google Patents

Nye kvaterniserede quinuclidinestere

Info

Publication number
DK1725552T3
DK1725552T3 DK05729711T DK05729711T DK1725552T3 DK 1725552 T3 DK1725552 T3 DK 1725552T3 DK 05729711 T DK05729711 T DK 05729711T DK 05729711 T DK05729711 T DK 05729711T DK 1725552 T3 DK1725552 T3 DK 1725552T3
Authority
DK
Denmark
Prior art keywords
quinuclidine esters
new
new quaternized
esters
quaternized quinuclidine
Prior art date
Application number
DK05729711T
Other languages
Danish (da)
English (en)
Inventor
Forner Maria Dolors Fernandez
Quinones Maria Prat
Albero Maria Antonia Buil
Original Assignee
Almirall Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Almirall Lab filed Critical Almirall Lab
Application granted granted Critical
Publication of DK1725552T3 publication Critical patent/DK1725552T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D453/00Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C07D453/02Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/439Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/02Nasal agents, e.g. decongestants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/02Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/10Drugs for disorders of the urinary system of the bladder
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/06Antiarrhythmics
DK05729711T 2004-03-15 2005-03-10 Nye kvaterniserede quinuclidinestere DK1725552T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ES200400638A ES2239546B1 (es) 2004-03-15 2004-03-15 Nuevos esteres de quinuclidina cuaternizados.
PCT/EP2005/002523 WO2005090342A1 (fr) 2004-03-15 2005-03-10 Nouveaux esters de quinuclidine quaternises

Publications (1)

Publication Number Publication Date
DK1725552T3 true DK1725552T3 (da) 2008-10-13

Family

ID=34955916

Family Applications (1)

Application Number Title Priority Date Filing Date
DK05729711T DK1725552T3 (da) 2004-03-15 2005-03-10 Nye kvaterniserede quinuclidinestere

Country Status (31)

Country Link
US (1) US20080214600A1 (fr)
EP (1) EP1725552B1 (fr)
JP (1) JP2007529444A (fr)
KR (1) KR20070003940A (fr)
CN (1) CN1930158A (fr)
AR (1) AR048004A1 (fr)
AT (1) ATE399166T1 (fr)
AU (1) AU2005223310A1 (fr)
BR (1) BRPI0508177A (fr)
CA (1) CA2560157A1 (fr)
CY (1) CY1108324T1 (fr)
DE (1) DE602005007714D1 (fr)
DK (1) DK1725552T3 (fr)
EC (1) ECSP066770A (fr)
ES (2) ES2239546B1 (fr)
HK (1) HK1101855A1 (fr)
HR (1) HRP20080338T3 (fr)
IL (1) IL177341A0 (fr)
MY (1) MY142036A (fr)
NO (1) NO20064659L (fr)
NZ (1) NZ548583A (fr)
PE (1) PE20060005A1 (fr)
PL (1) PL1725552T3 (fr)
PT (1) PT1725552E (fr)
RS (1) RS50566B (fr)
RU (1) RU2382041C2 (fr)
SI (1) SI1725552T1 (fr)
TW (1) TW200604196A (fr)
UA (1) UA88634C2 (fr)
WO (1) WO2005090342A1 (fr)
ZA (1) ZA200605931B (fr)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2165768B1 (es) 1999-07-14 2003-04-01 Almirall Prodesfarma Sa Nuevos derivados de quinuclidina y composiciones farmaceuticas que los contienen.
GB0424284D0 (en) * 2004-11-02 2004-12-01 Novartis Ag Organic compounds
ES2298049B1 (es) * 2006-07-21 2009-10-20 Laboratorios Almirall S.A. Procedimiento para fabricar bromuro de 3(r)-(2-hidroxi-2,2-ditien-2-ilacetoxi)-1-(3-fenoxipropil)-1-azoniabiciclo (2.2.2) octano.
KR20090110353A (ko) * 2007-02-15 2009-10-21 아젠터 디스커버리 리미티드 M3 무스카린 수용체로서의 헤테로시클릭 유도체
RU2480458C2 (ru) 2007-09-07 2013-04-27 Тереванс, Инк. Гуанидинсодержащие соединения, применимые в качестве антагонистов мускариновых рецепторов
CA2608561A1 (fr) * 2007-10-29 2009-04-29 Carl Paluszkiewicz Support d'accessoires de deflecteur pour motocyclette
EP2222637A1 (fr) 2007-12-14 2010-09-01 Theravance, Inc. Composés contenant de l'amidine utiles comme antagonistes du récepteur muscarinique
EP2100598A1 (fr) 2008-03-13 2009-09-16 Laboratorios Almirall, S.A. Composition à inhaler comprenant aclidinium pour le traitement de l'asthme et de maladies respiratoires obstructives chroniques
EP2100599A1 (fr) 2008-03-13 2009-09-16 Laboratorios Almirall, S.A. Composition à inhaler comprenant aclidinium pour le traitement de l'asthme et de maladies respiratoires obstructives chroniques
US20090326004A1 (en) 2008-06-03 2009-12-31 Ranbaxy Laboratories Limited Muscarinic receptor antagonists
CA2758100C (fr) 2009-04-09 2017-08-29 Novartis Ag Procede de preparation de sels de pyrrolidinium
EP2510928A1 (fr) 2011-04-15 2012-10-17 Almirall, S.A. Aclidinium pour l'amélioration du sommeil des patients avec des maldadies respiratoires
CN104837828B (zh) * 2012-12-05 2017-07-18 奇斯药制品公司 作为pde4‑抑制剂的苯基乙基吡啶衍生物
CN103755698A (zh) * 2014-01-06 2014-04-30 万特制药(海南)有限公司 一锅法制备阿地溴铵的工艺
CN103755699A (zh) * 2014-01-06 2014-04-30 万特制药(海南)有限公司 一种2-羟基-2,2-二噻吩-2-基乙酸-1-氮杂二环[2,2,2]辛-3(r)-基酯制备方法
KR101511090B1 (ko) 2014-04-24 2015-04-10 고려대학교 산학협력단 염증성 질환의 예방 또는 치료용 약학 조성물

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1219606A (en) * 1968-07-15 1971-01-20 Rech S Et D Applic Scient Soge Quinuclidinol derivatives and preparation thereof
US4843074A (en) * 1988-05-17 1989-06-27 Marion Laboratories, Inc. 1-azabicyclo[2.2.2]octan-3-yl 2-aryl-3-azacyclo-2-hydroxypropionates and their quaternary salts
ES2165768B1 (es) * 1999-07-14 2003-04-01 Almirall Prodesfarma Sa Nuevos derivados de quinuclidina y composiciones farmaceuticas que los contienen.
BR0116624A (pt) * 2000-12-28 2003-12-23 Almirall Prodesfarma Ag Composto, processo para produzir o mesmo, composição farmacêutica, uso do composto ou da composição farmacêutica, e, produto de combinação
US7361668B2 (en) * 2001-10-17 2008-04-22 Ucb, S.A. Quinuclidine derivatives processes for preparing them and their uses as m2 and/or m3 muscarinic receptor inhibitors
ES2204295B1 (es) * 2002-07-02 2005-08-01 Almirall Prodesfarma, S.A. Nuevos derivados de quinuclidina-amida.
AR044134A1 (es) * 2003-05-02 2005-08-24 Novartis Ag Derivados de quinuclidina, metodo de preparacion y composiciones farmaceuticas.

Also Published As

Publication number Publication date
UA88634C2 (en) 2009-11-10
NO20064659L (no) 2006-12-13
PE20060005A1 (es) 2006-01-28
ES2239546A1 (es) 2005-09-16
WO2005090342A1 (fr) 2005-09-29
TW200604196A (en) 2006-02-01
HK1101855A1 (en) 2007-10-26
DE602005007714D1 (de) 2008-08-07
US20080214600A1 (en) 2008-09-04
EP1725552A1 (fr) 2006-11-29
ES2239546B1 (es) 2006-12-01
BRPI0508177A (pt) 2007-08-07
PT1725552E (pt) 2008-09-18
CY1108324T1 (el) 2014-02-12
AU2005223310A1 (en) 2005-09-29
SI1725552T1 (sl) 2008-10-31
NZ548583A (en) 2010-05-28
RS50566B (sr) 2010-05-07
ZA200605931B (en) 2007-11-28
ES2307168T3 (es) 2008-11-16
EP1725552B1 (fr) 2008-06-25
JP2007529444A (ja) 2007-10-25
HRP20080338T3 (en) 2008-07-31
RU2382041C2 (ru) 2010-02-20
CN1930158A (zh) 2007-03-14
CA2560157A1 (fr) 2005-09-29
ATE399166T1 (de) 2008-07-15
AR048004A1 (es) 2006-03-15
PL1725552T3 (pl) 2008-12-31
RU2006136085A (ru) 2008-04-27
KR20070003940A (ko) 2007-01-05
IL177341A0 (en) 2006-12-10
MY142036A (en) 2010-08-16
ECSP066770A (es) 2006-11-16

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