DK170778A - Fremgangsmaade til fremstilling af n-alkyl-n-iminomethyl-derivater af thienamycin - Google Patents

Fremgangsmaade til fremstilling af n-alkyl-n-iminomethyl-derivater af thienamycin

Info

Publication number
DK170778A
DK170778A DK170778A DK170778A DK170778A DK 170778 A DK170778 A DK 170778A DK 170778 A DK170778 A DK 170778A DK 170778 A DK170778 A DK 170778A DK 170778 A DK170778 A DK 170778A
Authority
DK
Denmark
Prior art keywords
thienamycin
alkyl
procedure
making
iminomethyl
Prior art date
Application number
DK170778A
Other languages
Danish (da)
English (en)
Inventor
B G Christensen
W J Leanza
K J Wildonger
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of DK170778A publication Critical patent/DK170778A/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D477/00Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
    • C07D477/10Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D477/12Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6
    • C07D477/16Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6 with hetero atoms or carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 3
    • C07D477/20Sulfur atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C251/00Compounds containing nitrogen atoms doubly-bound to a carbon skeleton
    • C07C251/72Hydrazones

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
DK170778A 1977-05-05 1978-04-19 Fremgangsmaade til fremstilling af n-alkyl-n-iminomethyl-derivater af thienamycin DK170778A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US79397577A 1977-05-05 1977-05-05

Publications (1)

Publication Number Publication Date
DK170778A true DK170778A (da) 1979-01-15

Family

ID=25161306

Family Applications (1)

Application Number Title Priority Date Filing Date
DK170778A DK170778A (da) 1977-05-05 1978-04-19 Fremgangsmaade til fremstilling af n-alkyl-n-iminomethyl-derivater af thienamycin

Country Status (13)

Country Link
JP (1) JPS53137993A (de)
BE (1) BE866661A (de)
CH (1) CH637962A5 (de)
DE (1) DE2819453A1 (de)
DK (1) DK170778A (de)
ES (1) ES469426A1 (de)
FR (1) FR2389626B1 (de)
GB (1) GB1604275A (de)
IE (1) IE46873B1 (de)
IT (1) IT1104190B (de)
LU (1) LU79598A1 (de)
NL (1) NL7804229A (de)
SE (1) SE436569B (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT73791B (en) * 1980-10-17 1983-10-14 Merck & Co Inc Process for preparing 2-carbamimidoyl-6-substituted-1- -carbadethiapen-2-em-3-carboxylic acids

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3950357A (en) * 1974-11-25 1976-04-13 Merck & Co., Inc. Antibiotics
IL50911A (en) * 1975-11-21 1981-01-30 Merck & Co Inc Substituted n-methylene derivatives of thienamycin

Also Published As

Publication number Publication date
DE2819453A1 (de) 1978-11-09
CH637962A5 (en) 1983-08-31
FR2389626B1 (de) 1980-06-20
DE2819453C2 (de) 1993-02-25
BE866661A (fr) 1978-11-03
ES469426A1 (es) 1980-02-01
IE46873B1 (en) 1983-10-19
JPS53137993A (en) 1978-12-01
IE780849L (en) 1978-11-05
IT7849176A0 (it) 1978-05-03
NL7804229A (nl) 1978-11-07
SE7804447L (sv) 1978-11-06
IT1104190B (it) 1985-10-21
JPH0260678B2 (de) 1990-12-17
SE436569B (sv) 1985-01-07
LU79598A1 (fr) 1979-02-02
GB1604275A (en) 1981-12-09
FR2389626A1 (de) 1978-12-01

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Legal Events

Date Code Title Description
AHB Application shelved due to non-payment
B1 Patent granted (law 1993)