DK170514B1 - Præparat til reguleret frigivelse af carbidopa og levodopa - Google Patents

Præparat til reguleret frigivelse af carbidopa og levodopa Download PDF

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Publication number
DK170514B1
DK170514B1 DK302587A DK302587A DK170514B1 DK 170514 B1 DK170514 B1 DK 170514B1 DK 302587 A DK302587 A DK 302587A DK 302587 A DK302587 A DK 302587A DK 170514 B1 DK170514 B1 DK 170514B1
Authority
DK
Denmark
Prior art keywords
levodopa
soluble polymer
carbidopa
water
preparation
Prior art date
Application number
DK302587A
Other languages
Danish (da)
English (en)
Other versions
DK302587A (da
DK302587D0 (da
Inventor
Robert E Dempski
Edward C Scholtz
Donald W Nibbelink
Scott A Reines
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=25365017&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK170514(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of DK302587D0 publication Critical patent/DK302587D0/da
Publication of DK302587A publication Critical patent/DK302587A/da
Application granted granted Critical
Publication of DK170514B1 publication Critical patent/DK170514B1/da

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Neurosurgery (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
DK302587A 1986-06-16 1987-06-15 Præparat til reguleret frigivelse af carbidopa og levodopa DK170514B1 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US87498886A 1986-06-16 1986-06-16
US87498886 1986-06-16

Publications (3)

Publication Number Publication Date
DK302587D0 DK302587D0 (da) 1987-06-15
DK302587A DK302587A (da) 1987-12-17
DK170514B1 true DK170514B1 (da) 1995-10-09

Family

ID=25365017

Family Applications (1)

Application Number Title Priority Date Filing Date
DK302587A DK170514B1 (da) 1986-06-16 1987-06-15 Præparat til reguleret frigivelse af carbidopa og levodopa

Country Status (17)

Country Link
EP (1) EP0253490B1 (ko)
JP (1) JPS6354319A (ko)
KR (1) KR950002882B1 (ko)
AT (1) ATE58473T1 (ko)
AU (1) AU597670B2 (ko)
CY (1) CY1578A (ko)
DE (1) DE3766308D1 (ko)
DK (1) DK170514B1 (ko)
ES (1) ES2018548B3 (ko)
GR (1) GR3001102T3 (ko)
HK (1) HK56191A (ko)
IE (1) IE60508B1 (ko)
IL (1) IL82823A (ko)
NZ (1) NZ220599A (ko)
PT (1) PT85049B (ko)
SG (1) SG52191G (ko)
ZA (1) ZA874233B (ko)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4983400A (en) * 1986-06-16 1991-01-08 Merck & Co., Inc. Controlled release combination of carbidopa/levodopa
US4832957A (en) * 1987-12-11 1989-05-23 Merck & Co., Inc. Controlled release combination of carbidopa/levodopa
SE460947B (sv) * 1986-08-26 1989-12-11 Lejus Medical Ab En multiple-unit-dos komposition av l-dopa
US5095054A (en) * 1988-02-03 1992-03-10 Warner-Lambert Company Polymer compositions containing destructurized starch
IL94588A0 (en) * 1989-06-22 1991-04-15 Warner Lambert Co Polymer base blend compositions containing destructurized starch
CA2037178A1 (en) * 1990-02-28 1991-08-29 Albert Walter Brzeczko Deprenyl/l-dopa/carbidopa pharmaceutical composition
HU208495B (en) * 1990-06-27 1993-11-29 Alkaloida Vegyeszeti Gyar Process for producing retarde pharmaceutical compositions
US5624960A (en) * 1991-01-23 1997-04-29 Isis Pharma Gmbh Orally administrable drugs for the treatment of central dopamine deficiency conditions
DE4101873C2 (de) * 1991-01-23 1993-12-09 Isis Pharma Gmbh Peroral applizierbare Arzneiform zur Behandlung zentraler Dopaminmangelzustände
US5281420A (en) * 1992-05-19 1994-01-25 The Procter & Gamble Company Solid dispersion compositions of tebufelone
DE4341156C2 (de) * 1993-12-02 1997-11-13 Wacker Chemie Gmbh Verwendung von in Wasser redispergierbaren Kunststoffdispersionspulvern als Arzneimittelträger
GB9517062D0 (en) * 1995-08-18 1995-10-25 Scherer Ltd R P Pharmaceutical compositions
CA2216215A1 (en) * 1997-04-05 1998-10-05 Isa Odidi Controlled release formulations using intelligent polymers having opposing wettability characteristics of hydrophobicity and hydrophilicity
US5945424A (en) * 1998-07-31 1999-08-31 G & H Associates, Inc. Treatment of periodic limb movement syndrome
FI109453B (fi) * 1999-06-30 2002-08-15 Orion Yhtymae Oyj Farmaseuttinen koostumus
US6531153B2 (en) * 2001-05-29 2003-03-11 Drugtech Corporation Composition with sustained release of levodopa and carbidopa
US6682759B2 (en) * 2002-02-01 2004-01-27 Depomed, Inc. Manufacture of oral dosage forms delivering both immediate-release and sustained-release drugs
US9029427B2 (en) 2005-11-11 2015-05-12 Asahi Kasei Chemicals Corporation Controlled release solid preparation
WO2007113371A1 (en) * 2006-03-31 2007-10-11 Iprbox Oy Pharmaceutical composition and preparation method thereof
CA2711014C (en) 2007-12-28 2018-10-23 Impax Laboratories, Inc. Controlled release formulations of levodopa and uses thereof
TR201204839A2 (tr) 2012-04-25 2012-12-21 Ali̇ Rai̇f İlaç Sanayi̇ A.Ş. Uzatılmış salım sağlayan levodopa karbıdopa entakapon içeren tablet formülasyonu.
CN105120853A (zh) * 2013-03-28 2015-12-02 奥米尼埃克蒂夫健康科技有限公司 类胡萝卜素的脑内神经保护作用
CA2926082C (en) 2013-10-07 2022-06-14 Impax Laboratories, Inc. Muco-adhesive, controlled release formulations of levodopa and/or esters of levodopa and uses thereof
US10987313B2 (en) 2013-10-07 2021-04-27 Impax Laboratories, Llc Muco-adhesive, controlled release formulations of levodopa and/or esters of levodopa and uses thereof
WO2015127558A1 (en) * 2014-02-28 2015-09-03 UNIVERSITé LAVAL Methods and uses for inducing or facilitating micturition in a patient in need thereof
JP7066351B2 (ja) * 2017-08-18 2022-05-13 大原薬品工業株式会社 良好な徐放性を有する、レボドパ含有小型化錠剤
US11986449B2 (en) 2020-12-22 2024-05-21 Amneal Pharmaceuticals Llc Levodopa dosing regimen

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH468192A (de) * 1964-06-19 1969-02-15 Ciba Geigy Verfahren zur Herstellung von Arzneimitteln in Perlenform
US3632739A (en) * 1969-12-29 1972-01-04 Sandoz Ag Solid sustained release pharmaceutical preparation
ATE20311T1 (de) * 1981-07-08 1986-06-15 Key Pharma Polymerische diffusionsmatritze propranolol enthaltend.
US4369172A (en) * 1981-12-18 1983-01-18 Forest Laboratories Inc. Prolonged release therapeutic compositions based on hydroxypropylmethylcellulose

Also Published As

Publication number Publication date
AU597670B2 (en) 1990-06-07
DK302587A (da) 1987-12-17
NZ220599A (en) 1990-10-26
DE3766308D1 (de) 1991-01-03
DK302587D0 (da) 1987-06-15
GR3001102T3 (en) 1992-05-12
JPH0445B2 (ko) 1992-01-06
AU7422887A (en) 1987-12-17
EP0253490B1 (en) 1990-11-22
ATE58473T1 (de) 1990-12-15
IE60508B1 (en) 1994-07-27
PT85049A (en) 1987-07-01
PT85049B (pt) 1990-03-08
IL82823A0 (en) 1987-12-20
ZA874233B (en) 1987-12-14
HK56191A (en) 1991-07-26
SG52191G (en) 1991-08-23
EP0253490A1 (en) 1988-01-20
KR880000086A (ko) 1988-03-23
CY1578A (en) 1991-12-20
JPS6354319A (ja) 1988-03-08
IE871559L (en) 1987-12-16
ES2018548B3 (es) 1991-04-16
IL82823A (en) 1991-03-10
KR950002882B1 (ko) 1995-03-28

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Legal Events

Date Code Title Description
B1 Patent granted (law 1993)
PUP Patent expired