DK1687401T3 - Sted-spicifik inkorporing af redoxaktive aminosyrer i protiener - Google Patents

Sted-spicifik inkorporing af redoxaktive aminosyrer i protiener

Info

Publication number
DK1687401T3
DK1687401T3 DK04795276.7T DK04795276T DK1687401T3 DK 1687401 T3 DK1687401 T3 DK 1687401T3 DK 04795276 T DK04795276 T DK 04795276T DK 1687401 T3 DK1687401 T3 DK 1687401T3
Authority
DK
Denmark
Prior art keywords
protiens
redox
site
amino acids
active amino
Prior art date
Application number
DK04795276.7T
Other languages
Danish (da)
English (en)
Inventor
Lital Alfonta
Peter G Schultz
Zhiwen Zhang
Original Assignee
Scripps Research Inst
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Scripps Research Inst filed Critical Scripps Research Inst
Application granted granted Critical
Publication of DK1687401T3 publication Critical patent/DK1687401T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/93—Ligases (6)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
DK04795276.7T 2003-10-14 2004-10-13 Sted-spicifik inkorporing af redoxaktive aminosyrer i protiener DK1687401T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US51153203P 2003-10-14 2003-10-14
PCT/US2004/034089 WO2005038002A2 (en) 2003-10-14 2004-10-13 Site-specific incorporation of redox active amino acids into proteins

Publications (1)

Publication Number Publication Date
DK1687401T3 true DK1687401T3 (da) 2013-02-04

Family

ID=34465242

Family Applications (1)

Application Number Title Priority Date Filing Date
DK04795276.7T DK1687401T3 (da) 2003-10-14 2004-10-13 Sted-spicifik inkorporing af redoxaktive aminosyrer i protiener

Country Status (14)

Country Link
US (5) US8008041B2 (cg-RX-API-DMAC7.html)
EP (1) EP1687401B1 (cg-RX-API-DMAC7.html)
JP (1) JP5657850B2 (cg-RX-API-DMAC7.html)
CN (2) CN1942579B (cg-RX-API-DMAC7.html)
AU (1) AU2004282577B2 (cg-RX-API-DMAC7.html)
BR (1) BRPI0415308A (cg-RX-API-DMAC7.html)
CA (1) CA2541166A1 (cg-RX-API-DMAC7.html)
DK (1) DK1687401T3 (cg-RX-API-DMAC7.html)
ES (1) ES2396712T3 (cg-RX-API-DMAC7.html)
IL (3) IL174947A (cg-RX-API-DMAC7.html)
MX (1) MXPA06004087A (cg-RX-API-DMAC7.html)
PL (1) PL1687401T3 (cg-RX-API-DMAC7.html)
PT (1) PT1687401E (cg-RX-API-DMAC7.html)
WO (1) WO2005038002A2 (cg-RX-API-DMAC7.html)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL158418A0 (en) * 2001-04-19 2004-05-12 Scripps Research Inst In vivo incorporation of unnatural amino acids
AU2003286436B2 (en) * 2002-10-16 2010-08-19 The Scripps Research Institute Glycoprotein synthesis
EP1613735B1 (en) 2003-04-17 2012-01-25 The Scripps Research Institute Expanding the eukaryotic genetic code
EP1636340A4 (en) 2003-06-18 2009-02-11 Scripps Research Inst COMPLEMENTS TO THE GENETIC CODE OF UNNATURATIVE REACTIVE AMINO ACIDS
PT1666604E (pt) * 2003-07-07 2008-05-19 Scripps Research Inst Composições de pares ortogonais de lisil-arnt e aminoacil-arnt-sintetase e suas utilizações
US7399619B2 (en) * 2004-05-25 2008-07-15 The Scripps Research Institute Site specific incorporation of heavy atom-containing unnatural amino acids into proteins for structure determination
DE102004031258A1 (de) * 2004-06-29 2006-02-09 Jennissen, Herbert P., Prof. Dr. Proteinhybride mit polyhydroxyaromatischen Aminosäure-Epitopen
US20060110784A1 (en) * 2004-09-22 2006-05-25 The Scripps Research Institute Site-specific labeling of proteins for NMR studies
EP2380982B1 (en) 2004-10-27 2014-07-16 The Scripps Research Institute Orthogonal translation components for the in vivo incorporation of unnatural amino acids
CN104789536A (zh) * 2005-10-12 2015-07-22 斯克利普斯研究院 噬菌体展示多肽的选择性翻译后修饰
WO2007092475A2 (en) * 2006-02-06 2007-08-16 Franklin And Marshall College Site-specific incorporation of fluorinated amino acids into proteins
JP5589186B2 (ja) * 2006-03-09 2014-09-17 ザ スクリプス リサーチ インスティテュート 真正細菌宿主細胞における直交翻訳成分の発現システム
WO2007109035A2 (en) 2006-03-16 2007-09-27 The Scripps Research Institute Genetically programmed expression of proteins containing the unnatural amino acid phenylselenocysteine
EP2018429A4 (en) * 2006-05-23 2010-07-14 Scrips Res Inst GENETICALLY ENCODED FLUORESCENT CUMARIN AMINO ACIDS
EP2052083B1 (en) * 2006-09-21 2014-01-08 The Scripps Research Institute Genetically programmed expression of selectively sulfated proteins in eubacteria
CN101535338A (zh) 2006-10-18 2009-09-16 斯克利普斯研究院 在哺乳动物细胞中将非天然氨基酸遗传掺入蛋白质
WO2008137452A1 (en) * 2007-05-04 2008-11-13 Kenergy Royalty Company, Llc Implantable high efficiency digital stimulation device
CA2703736A1 (en) * 2007-10-25 2009-04-30 The Scripps Research Institute Genetic incorporation of 3-aminotyrosine into reductases
EP2220218A4 (en) * 2007-11-02 2010-12-08 Scripps Research Inst GENETICALLY ENCODED BORONATE AMINO ACID
EP2217702A4 (en) 2007-11-02 2012-05-16 Scripps Research Inst DIRECTED EVOLUTION USING PROTEINS WITH NON-NATURAL AMINO ACIDS
EP2231856A4 (en) * 2007-12-11 2011-05-18 Scripps Research Inst IN VIVO EXPRESSION OF NON-NATURAL AMINO ACIDS IN THE METHYLOTROPHIC YEAST PICHIA PASTORIS
BRPI0906388A2 (pt) * 2008-02-08 2015-07-07 Scripps Research Inst Quebra de tolerância imunológica com um aminoácido não natural geneticamente codificado
CA2746213A1 (en) * 2008-12-09 2010-07-08 Wilson-Cook Medical Inc. Apparatus and methods for controlled release of tacking devices
US20090197339A1 (en) * 2008-12-10 2009-08-06 The Scripps Research Institute In vivo unnatural amino acid expression in the methylotrophic yeast pichia pastoris
WO2010068278A2 (en) 2008-12-10 2010-06-17 The Scripps Research Institute Production of carrier-peptide conjugates using chemically reactive unnatural amino acids
EP2394323B1 (en) * 2009-02-04 2017-05-24 Ben-gurion University Of The Negev Research And Development Authority Systems and methods for bio-electricity production
EP2976362B1 (en) 2013-03-19 2019-10-23 Beijing Shenogen Pharma Group Ltd. Antibodies and methods for treating estrogen receptor-associated diseases
US20150331624A1 (en) * 2014-05-19 2015-11-19 Kabushiki Kaisha Toshiba Host-controlled flash translation layer snapshot
KR101956042B1 (ko) * 2017-07-13 2019-03-08 서강대학교산학협력단 표적 단백질 내 l-디하이드록시페닐알라닌의 도입 방법
CN114008176A (zh) 2019-06-17 2022-02-01 默克专利股份有限公司 基于液晶的光阀

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5879905A (en) * 1996-08-29 1999-03-09 Massachusetts Institute Of Technology In vivo method of initiating protein synthesis with an amino acid other than methionine
IL158418A0 (en) * 2001-04-19 2004-05-12 Scripps Research Inst In vivo incorporation of unnatural amino acids
ATE429500T1 (de) 2002-10-16 2009-05-15 Scripps Research Inst Stellenspezifischer einbau von ketoaminosäuren in proteine
AU2003286436B2 (en) 2002-10-16 2010-08-19 The Scripps Research Institute Glycoprotein synthesis
WO2004058946A2 (en) 2002-12-22 2004-07-15 The Scripps Research Institute Protein arrays
EP1613735B1 (en) 2003-04-17 2012-01-25 The Scripps Research Institute Expanding the eukaryotic genetic code
EP1636340A4 (en) 2003-06-18 2009-02-11 Scripps Research Inst COMPLEMENTS TO THE GENETIC CODE OF UNNATURATIVE REACTIVE AMINO ACIDS
EP1704242A4 (en) 2003-07-07 2008-06-18 Scripps Research Inst COMPOSITIONS WITH PAIRS OF ORTHOGONAL LEUCYL-TRNA AND AMINOACYL-TRNA-SYNTHETASE AND USES THEREOF
PT1666604E (pt) 2003-07-07 2008-05-19 Scripps Research Inst Composições de pares ortogonais de lisil-arnt e aminoacil-arnt-sintetase e suas utilizações
EP1658366A4 (en) 2003-07-07 2006-08-09 Scripps Research Inst COMPOSITIONS OF ORTHOGONAL GLUTAMYL-TRNA AND AMINOACYL-TRNA-SYNTHETASEPAARES AND THEIR USES

Also Published As

Publication number Publication date
BRPI0415308A (pt) 2006-12-05
CN1942579B (zh) 2013-06-26
EP1687401A2 (en) 2006-08-09
AU2004282577A1 (en) 2005-04-28
IL201705A0 (en) 2011-08-01
US8008041B2 (en) 2011-08-30
US20120100570A1 (en) 2012-04-26
US20090298124A1 (en) 2009-12-03
IL206889A0 (en) 2010-12-30
PL1687401T3 (pl) 2013-04-30
JP2007508034A (ja) 2007-04-05
CN1942579A (zh) 2007-04-04
US7494796B2 (en) 2009-02-24
US9783798B2 (en) 2017-10-10
EP1687401A4 (en) 2007-08-01
US7811801B2 (en) 2010-10-12
IL174947A (en) 2011-11-30
US20110008782A1 (en) 2011-01-13
EP1687401B1 (en) 2012-11-21
PT1687401E (pt) 2013-02-26
US20050227318A1 (en) 2005-10-13
US20070009990A1 (en) 2007-01-11
IL174947A0 (en) 2006-08-20
CA2541166A1 (en) 2005-04-28
ES2396712T3 (es) 2013-02-25
JP5657850B2 (ja) 2015-01-21
MXPA06004087A (es) 2006-06-27
CN101532046A (zh) 2009-09-16
US8114654B2 (en) 2012-02-14
WO2005038002A3 (en) 2006-11-23
AU2004282577B2 (en) 2009-10-29
WO2005038002A2 (en) 2005-04-28

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