DK167561B1 - Anvendelse af vaevsplasminogenaktivator (tpa) til fremstilling af et middel til diagnostisk og prognostisk afklaring af ondartede tumorer samt til fremstilling af et laegemiddel til terapeutisk behandling af saadanne tumorer - Google Patents

Anvendelse af vaevsplasminogenaktivator (tpa) til fremstilling af et middel til diagnostisk og prognostisk afklaring af ondartede tumorer samt til fremstilling af et laegemiddel til terapeutisk behandling af saadanne tumorer Download PDF

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Publication number
DK167561B1
DK167561B1 DK377588A DK377588A DK167561B1 DK 167561 B1 DK167561 B1 DK 167561B1 DK 377588 A DK377588 A DK 377588A DK 377588 A DK377588 A DK 377588A DK 167561 B1 DK167561 B1 DK 167561B1
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DK
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Prior art keywords
tpa
use according
fragment
contained
derivative
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DK377588A
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Danish (da)
English (en)
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DK377588D0 (da
DK377588A (da
Inventor
Sirkka-Liisa Karonen
Jan Lindgren
Hannu Aronen
Original Assignee
Boehringer Ingelheim Int
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Application filed by Boehringer Ingelheim Int filed Critical Boehringer Ingelheim Int
Publication of DK377588D0 publication Critical patent/DK377588D0/da
Publication of DK377588A publication Critical patent/DK377588A/da
Application granted granted Critical
Publication of DK167561B1 publication Critical patent/DK167561B1/da

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B6/00—Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/6456—Plasminogen activators
    • C12N9/6459—Plasminogen activators t-plasminogen activator (3.4.21.68), i.e. tPA
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21—Serine endopeptidases (3.4.21)
    • C12Y304/21069—Protein C activated (3.4.21.69)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2121/00—Preparations for use in therapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2123/00—Preparations for testing in vivo
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medical Informatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Optics & Photonics (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Radiology & Medical Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Biophysics (AREA)
  • High Energy & Nuclear Physics (AREA)
  • Microbiology (AREA)
  • Pathology (AREA)
  • Biotechnology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Motorcycle And Bicycle Frame (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK377588A 1987-07-08 1988-07-07 Anvendelse af vaevsplasminogenaktivator (tpa) til fremstilling af et middel til diagnostisk og prognostisk afklaring af ondartede tumorer samt til fremstilling af et laegemiddel til terapeutisk behandling af saadanne tumorer DK167561B1 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19873722522 DE3722522A1 (de) 1987-07-08 1987-07-08 Verwendung eines vehikels mit hoher affinitaet zu tumoren
DE3722522 1987-07-08

Publications (3)

Publication Number Publication Date
DK377588D0 DK377588D0 (da) 1988-07-07
DK377588A DK377588A (da) 1989-01-09
DK167561B1 true DK167561B1 (da) 1993-11-22

Family

ID=6331118

Family Applications (1)

Application Number Title Priority Date Filing Date
DK377588A DK167561B1 (da) 1987-07-08 1988-07-07 Anvendelse af vaevsplasminogenaktivator (tpa) til fremstilling af et middel til diagnostisk og prognostisk afklaring af ondartede tumorer samt til fremstilling af et laegemiddel til terapeutisk behandling af saadanne tumorer

Country Status (13)

Country Link
EP (1) EP0298436B1 (enExample)
JP (1) JPH01125331A (enExample)
KR (1) KR890001508A (enExample)
AT (1) ATE81473T1 (enExample)
AU (1) AU623080B2 (enExample)
DE (2) DE3722522A1 (enExample)
DK (1) DK167561B1 (enExample)
ES (1) ES2046244T3 (enExample)
FI (1) FI883177A7 (enExample)
GR (1) GR3006404T3 (enExample)
NO (1) NO883040L (enExample)
NZ (1) NZ225350A (enExample)
ZA (1) ZA884870B (enExample)

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA831399B (en) * 1982-03-05 1984-02-29 Health Lab Service Board New fibrinolytic enzymes and methods for their production and pharmaceutical compositions containing them
US4663146A (en) * 1983-07-29 1987-05-05 Codon Genetic Engineering Laboratories Methods and compositions for the diagnosis of bloodclots using plasminogen activator

Also Published As

Publication number Publication date
KR890001508A (ko) 1989-03-27
DK377588D0 (da) 1988-07-07
FI883177L (fi) 1989-01-09
ATE81473T1 (de) 1992-10-15
ZA884870B (en) 1989-04-26
AU1889588A (en) 1989-01-12
GR3006404T3 (enExample) 1993-06-21
EP0298436A2 (de) 1989-01-11
EP0298436A3 (en) 1990-01-17
FI883177A0 (fi) 1988-07-04
DE3875290D1 (de) 1992-11-19
NZ225350A (en) 1991-07-26
DK377588A (da) 1989-01-09
EP0298436B1 (de) 1992-10-14
AU623080B2 (en) 1992-05-07
JPH01125331A (ja) 1989-05-17
NO883040L (no) 1989-01-09
NO883040D0 (no) 1988-07-07
FI883177A7 (fi) 1989-01-09
DE3722522A1 (de) 1989-01-19
ES2046244T3 (es) 1994-02-01

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Legal Events

Date Code Title Description
B1 Patent granted (law 1993)
PBP Patent lapsed