DK165733C - Anvendelse af dipeptiderivater til fremstilling a f laegemidler til forhindring eller behandling af posttraumatiske nerveskader efter ved uheld fremkaldte rygmarvs- og/eller hjernetraumer. - Google Patents

Anvendelse af dipeptiderivater til fremstilling a f laegemidler til forhindring eller behandling af posttraumatiske nerveskader efter ved uheld fremkaldte rygmarvs- og/eller hjernetraumer.

Info

Publication number
DK165733C
DK165733C DK032786A DK32786A DK165733C DK 165733 C DK165733 C DK 165733C DK 032786 A DK032786 A DK 032786A DK 32786 A DK32786 A DK 32786A DK 165733 C DK165733 C DK 165733C
Authority
DK
Denmark
Prior art keywords
treatment
stands
hydrogen atom
posttraumatic
preparation
Prior art date
Application number
DK032786A
Other languages
Danish (da)
English (en)
Other versions
DK165733B (da
DK32786D0 (da
DK32786A (da
Inventor
Hubert Giertz
Hans Barth
Leopold Flohe
Original Assignee
Gruenenthal Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gruenenthal Gmbh filed Critical Gruenenthal Gmbh
Publication of DK32786D0 publication Critical patent/DK32786D0/da
Publication of DK32786A publication Critical patent/DK32786A/da
Publication of DK165733B publication Critical patent/DK165733B/da
Application granted granted Critical
Publication of DK165733C publication Critical patent/DK165733C/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0821—Tripeptides with the first amino acid being heterocyclic, e.g. His, Pro, Trp
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/06—Tripeptides
    • A61K38/066—TRH, thyroliberin, thyrotropin releasing hormone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Neurology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurosurgery (AREA)
  • Endocrinology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Diabetes (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
DK032786A 1985-01-23 1986-01-22 Anvendelse af dipeptiderivater til fremstilling a f laegemidler til forhindring eller behandling af posttraumatiske nerveskader efter ved uheld fremkaldte rygmarvs- og/eller hjernetraumer. DK165733C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE3502041 1985-01-23
DE19853502041 DE3502041A1 (de) 1985-01-23 1985-01-23 Verwendung von dipeptidderivaten zur behandlung posttraumatischer nervenschaeden

Publications (4)

Publication Number Publication Date
DK32786D0 DK32786D0 (da) 1986-01-22
DK32786A DK32786A (da) 1986-07-24
DK165733B DK165733B (da) 1993-01-11
DK165733C true DK165733C (da) 1993-06-07

Family

ID=6260477

Family Applications (1)

Application Number Title Priority Date Filing Date
DK032786A DK165733C (da) 1985-01-23 1986-01-22 Anvendelse af dipeptiderivater til fremstilling a f laegemidler til forhindring eller behandling af posttraumatiske nerveskader efter ved uheld fremkaldte rygmarvs- og/eller hjernetraumer.

Country Status (11)

Country Link
US (1) US4906614A (xx)
EP (1) EP0188810B1 (xx)
JP (1) JPS61172828A (xx)
AT (1) ATE57834T1 (xx)
AU (1) AU578999B2 (xx)
DE (2) DE3502041A1 (xx)
DK (1) DK165733C (xx)
IE (1) IE58805B1 (xx)
IL (1) IL77218A (xx)
SG (1) SG83791G (xx)
ZA (1) ZA859187B (xx)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0382842B1 (en) * 1987-04-08 1993-09-22 Grünenthal GmbH Nootropic
US5686420A (en) * 1987-06-05 1997-11-11 Georgetown University Thyrotropin-releasing hormone analogs and method of use
JPS63316724A (ja) * 1987-06-19 1988-12-26 Nippon Shinyaku Co Ltd 抗けいれん剤
US5049553A (en) * 1990-01-04 1991-09-17 E. R. Squibb & Sons, Inc. Method for preventing or treating symptoms resulting from closed head injuries employing an ace inhibitor
US6812208B2 (en) 1993-12-23 2004-11-02 Neuronz Ltd. Methods to improve neural outcome
EP0735894A4 (en) 1993-12-23 1999-08-18 Auckland Uniservices Ltd COMPOSITION AND METHODS FOR IMPROVING THE OUTCOME OF NERVOUS SYSTEM CONDITIONS
US5897858A (en) 1994-02-03 1999-04-27 Schering-Plough Healthcare Products, Inc. Nasal spray compositions exhibiting increased retention in the nasal cavity
US6187906B1 (en) * 1997-08-11 2001-02-13 Aukland Uniservices Limited Methods to improve neural outcome
US6475989B1 (en) 1997-10-09 2002-11-05 Albert Sattin Use of pyroglutamyl-glutamyl-prolyl amide (EEP) for neurological and neurobehavioral disorders
US20050233973A1 (en) * 1997-10-09 2005-10-20 Albert Sattin Tri-peptides for antidepressant applications
US20020151502A1 (en) * 1997-10-09 2002-10-17 Albert Sattin Tri-peptides for neurological and neurobehavior applications
US6815425B1 (en) 1999-10-22 2004-11-09 The United States Of America As Represented By The Secretary Of The Army Pharmaceutical composition containing pGLU-GLU-PRO-NH2 and method for treating diseases and injuries to the brain, spinal cord and retina using same
WO2001028578A2 (en) * 1999-10-22 2001-04-26 Wrair A PHARMACEUTICAL COMPOSITION CONTAINING pGLU-GLU-PRO-NH2 AND METHOD FOR TREATING DISEASES AND INJURIES TO THE BRAIN, SPINAL CORD AND RETINA USING SAME
IE20000240A1 (en) * 2000-02-17 2003-03-05 Trinity College Dublin TRH-like peptide derivatives
US7112570B2 (en) * 2000-08-24 2006-09-26 Neuren Pharmaceuticals, Ltd. GPE analogs
AU2001289160A1 (en) * 2000-08-24 2002-03-04 Neuronz Ltd. Gpe analogs
US20070004641A1 (en) * 2001-05-24 2007-01-04 Neuren Pharmaceuticals Limited Cognitive enhancement and cognitive therapy using glycyl-L-2-methylprolyl-L-glutamate
US7605177B2 (en) * 2001-05-24 2009-10-20 Neuren Pharmaceuticals Limited Effects of glycyl-2 methyl prolyl glutamate on neurodegeneration
US7714020B2 (en) * 2001-05-24 2010-05-11 Neuren Pharmaceuticals Limited Treatment of non-convulsive seizures in brain injury using G-2-methyl-prolyl glutamate
ATE435852T1 (de) 2001-05-24 2009-07-15 Neuren Pharmaceuticals Ltd Gpe-analoga und peptidomimetika
US8791117B2 (en) 2003-09-03 2014-07-29 Neuren Pharmaceuticals Limited Cyclic glycyl-2-allyl proline improves cognitive performance in impaired animals
US7462595B2 (en) * 2004-09-17 2008-12-09 Prange Jr Arthur Jergen Methods for treating cancer-related fatigue
WO2006038206A2 (en) * 2004-10-01 2006-04-13 The Provost, Fellows And Scholars Of The College Of The Holy And Undivided Trinity Of Queen Elizabeth Near Dublin Compounds that modulate trh actions and inhibit the trh-degrading enzyme
WO2015013397A2 (en) 2013-07-25 2015-01-29 Neuren Pharmaceuticals Limited Neuroprotective bicyclic compounds and methods for their use in treating autism spectrum disorders and neurodevelopmental disorders

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2449167C2 (de) 1974-10-16 1984-05-24 Grünenthal GmbH, 5190 Stolberg N-Acyl-L-histidyl-L-prolinamide, Verfahren zu deren Herstellung und diese Verbindungen enthaltende pharmazeutische Zubereitungen
DE2615455C2 (de) 1976-04-09 1985-06-20 Grünenthal GmbH, 5190 Stolberg N-Acyl-L-histidyl-L-prolin (N-substituierte)-amide, Verfahren zu deren Herstellung und diese Verbindungen enthaltende pharmazeutische Zubereitungen
US4608365A (en) * 1984-03-30 1986-08-26 University Of Southern California Treatment of neurologic functions

Also Published As

Publication number Publication date
JPS61172828A (ja) 1986-08-04
DK165733B (da) 1993-01-11
JPH0584286B2 (xx) 1993-12-01
IE852905L (en) 1986-07-23
DK32786D0 (da) 1986-01-22
DE3502041A1 (de) 1986-07-24
EP0188810B1 (de) 1990-10-31
US4906614A (en) 1990-03-06
EP0188810A2 (de) 1986-07-30
ATE57834T1 (de) 1990-11-15
DK32786A (da) 1986-07-24
IE58805B1 (en) 1993-11-17
AU5260186A (en) 1986-07-31
AU578999B2 (en) 1988-11-10
SG83791G (en) 1991-11-22
DE3580351D1 (de) 1990-12-06
EP0188810A3 (en) 1988-09-07
ZA859187B (en) 1986-08-27
IL77218A (en) 1990-11-05

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