DK165677A - Fremgangsmade til fremstilling af thiourinstofderivater - Google Patents

Fremgangsmade til fremstilling af thiourinstofderivater

Info

Publication number
DK165677A
DK165677A DK165677A DK165677A DK165677A DK 165677 A DK165677 A DK 165677A DK 165677 A DK165677 A DK 165677A DK 165677 A DK165677 A DK 165677A DK 165677 A DK165677 A DK 165677A
Authority
DK
Denmark
Prior art keywords
thiourin
procedure
preparation
substance derivatives
derivatives
Prior art date
Application number
DK165677A
Other languages
Danish (da)
English (en)
Inventor
M R Cohen
R W Kierstead
J W Tilley
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of DK165677A publication Critical patent/DK165677A/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/12Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
    • C07D295/125Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/13Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C279/00Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
    • C07C279/18Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to carbon atoms of six-membered aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C335/00Thioureas, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C335/04Derivatives of thiourea
    • C07C335/16Derivatives of thiourea having nitrogen atoms of thiourea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C335/00Thioureas, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C335/30Isothioureas
    • C07C335/32Isothioureas having sulfur atoms of isothiourea groups bound to acyclic carbon atoms

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Compositions Of Oxide Ceramics (AREA)
  • Ceramic Products (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK165677A 1976-04-15 1977-04-14 Fremgangsmade til fremstilling af thiourinstofderivater DK165677A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US67710676A 1976-04-15 1976-04-15

Publications (1)

Publication Number Publication Date
DK165677A true DK165677A (da) 1977-10-16

Family

ID=24717351

Family Applications (1)

Application Number Title Priority Date Filing Date
DK165677A DK165677A (da) 1976-04-15 1977-04-14 Fremgangsmade til fremstilling af thiourinstofderivater

Country Status (26)

Country Link
US (2) US4066695A (xx)
JP (1) JPS52128332A (xx)
AR (1) AR218247A1 (xx)
AT (1) AT353282B (xx)
AU (1) AU509570B2 (xx)
BE (1) BE853578A (xx)
DE (1) DE2716838A1 (xx)
DK (1) DK165677A (xx)
ES (1) ES457805A1 (xx)
FI (1) FI771199A (xx)
FR (1) FR2350340A1 (xx)
GB (1) GB1579181A (xx)
GR (1) GR63193B (xx)
HU (1) HU176110B (xx)
IE (1) IE44425B1 (xx)
IL (1) IL51850A (xx)
IT (1) IT1075834B (xx)
LU (1) LU77137A1 (xx)
MC (1) MC1143A1 (xx)
NL (1) NL7704153A (xx)
NO (1) NO771309L (xx)
NZ (1) NZ183848A (xx)
PH (1) PH13392A (xx)
PT (1) PT66440B (xx)
SE (1) SE7704322L (xx)
ZA (1) ZA772083B (xx)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1980000151A1 (en) * 1978-07-03 1980-02-07 American Home Prod N-(3-alkylaminopropyl)-n'-phenylureas
US4224242A (en) * 1978-07-03 1980-09-23 American Home Products Corporation N-[3-(lower)alkylaminopropyl]-N'-(disubstituted)phenylureas
US4290971A (en) * 1979-01-19 1981-09-22 Dso "Pharmachim" Method of preparing 2-(phenylamino)-imidazolines-(2)
US4348413A (en) * 1979-05-21 1982-09-07 American Home Products Corporation Anti-arrhythmic N-[3-alkylaminopropyl]-N'-phenylureas
DE3064249D1 (en) * 1979-07-03 1983-08-25 Ciba Geigy Ag Thio-urea derivatives and isothio-urea derivatives, process for their preparation, compositions containing these compounds and their use in combating pests
US4328247A (en) * 1979-09-19 1982-05-04 Ciba-Geigy Corporation Phenoxyphenylisothioureas, production thereof and use thereof in pest control, and phenoxyphenylthioureas as intermediates for the production of the phenoxyphenylisothioureas and use thereof in pest control
US4474707A (en) * 1980-10-09 1984-10-02 American Home Products Corporation N-3-Propenylaminopropyl-N'-phenylureas
US4399286A (en) * 1981-07-16 1983-08-16 Mead Johnson & Company Antiarrhythmic phenethylpiperidine compounds
IL102548A (en) * 1991-08-02 1998-08-16 Medivir Ab Use of painting derivatives in the preparation of drugs for VIH inhibition and treatment of SDIA and new compounds
US5593993A (en) * 1991-08-02 1997-01-14 Medivir Ab Method for inhibition of HIV related viruses

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2849306A (en) * 1954-03-19 1958-08-26 Du Pont Herbicidal method and composition employing aryl pseudoureas
US3717633A (en) * 1965-10-01 1973-02-20 Boehringer Sohn Ingelheim 2-anilino-1,3-diazacyclopentene-(2) derivative
DE1618158A1 (de) * 1967-05-16 1970-10-29 Boehringer Sohn Ingelheim Verfahren zur Herstellung neuer Guanidinderivate
US3950537A (en) * 1973-06-29 1976-04-13 Rohm And Haas Company Gastrointestinally active thioureas

Also Published As

Publication number Publication date
ES457805A1 (es) 1978-11-01
MC1143A1 (fr) 1978-01-30
IL51850A (en) 1980-03-31
IT1075834B (it) 1985-04-22
AT353282B (de) 1979-11-12
PH13392A (en) 1980-03-28
FR2350340A1 (fr) 1977-12-02
NO771309L (no) 1977-10-18
PT66440A (en) 1977-05-01
AR218247A1 (es) 1980-05-30
SE7704322L (sv) 1977-10-16
FI771199A (xx) 1977-10-16
JPS52128332A (en) 1977-10-27
IE44425L (en) 1977-10-15
GB1579181A (en) 1980-11-12
BE853578A (fr) 1977-10-14
IL51850A0 (en) 1977-06-30
LU77137A1 (xx) 1978-06-01
US4066695A (en) 1978-01-03
US4096276A (en) 1978-06-20
PT66440B (en) 1979-03-09
ATA262977A (de) 1979-04-15
NZ183848A (en) 1978-09-20
HU176110B (en) 1980-12-28
DE2716838A1 (de) 1977-10-27
AU2425377A (en) 1978-10-19
NL7704153A (nl) 1977-10-18
ZA772083B (en) 1978-03-29
GR63193B (en) 1979-10-04
AU509570B2 (en) 1980-05-15
IE44425B1 (en) 1981-11-18

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Legal Events

Date Code Title Description
AHS Application shelved for other reasons than non-payment
PBP Patent lapsed