DK163919C - Analogifremgangsmaade til fremstilling af blodpladeaggregationsinhiberende nipecotinsyrederivater - Google Patents

Analogifremgangsmaade til fremstilling af blodpladeaggregationsinhiberende nipecotinsyrederivater

Info

Publication number
DK163919C
DK163919C DK167083A DK167083A DK163919C DK 163919 C DK163919 C DK 163919C DK 167083 A DK167083 A DK 167083A DK 167083 A DK167083 A DK 167083A DK 163919 C DK163919 C DK 163919C
Authority
DK
Denmark
Prior art keywords
preparation
acid derivatives
platelet aggregation
aggregation inhibitor
nipecotic acid
Prior art date
Application number
DK167083A
Other languages
Danish (da)
English (en)
Other versions
DK163919B (da
DK167083D0 (da
DK167083A (da
Inventor
Andrew Lasslo
Ronald P Quintana
Marion Dugdale
Randy W Johnson
Original Assignee
Research Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Research Corp filed Critical Research Corp
Publication of DK167083D0 publication Critical patent/DK167083D0/da
Publication of DK167083A publication Critical patent/DK167083A/da
Publication of DK163919B publication Critical patent/DK163919B/da
Application granted granted Critical
Publication of DK163919C publication Critical patent/DK163919C/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/60—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Quinoline Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
DK167083A 1982-04-15 1983-04-15 Analogifremgangsmaade til fremstilling af blodpladeaggregationsinhiberende nipecotinsyrederivater DK163919C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US36886382 1982-04-15
US06/368,863 US4443450A (en) 1982-04-15 1982-04-15 Platelet aggregation inhibitory agents and intermediates therefor

Publications (4)

Publication Number Publication Date
DK167083D0 DK167083D0 (da) 1983-04-15
DK167083A DK167083A (da) 1983-10-16
DK163919B DK163919B (da) 1992-04-21
DK163919C true DK163919C (da) 1992-09-21

Family

ID=23453081

Family Applications (1)

Application Number Title Priority Date Filing Date
DK167083A DK163919C (da) 1982-04-15 1983-04-15 Analogifremgangsmaade til fremstilling af blodpladeaggregationsinhiberende nipecotinsyrederivater

Country Status (12)

Country Link
US (1) US4443450A (fr)
EP (1) EP0096735B1 (fr)
JP (1) JPS58192869A (fr)
AU (1) AU556925B2 (fr)
CA (1) CA1256438A (fr)
DE (1) DE3380875D1 (fr)
DK (1) DK163919C (fr)
ES (2) ES521794A0 (fr)
GR (1) GR78182B (fr)
IE (1) IE55561B1 (fr)
IL (1) IL68423A (fr)
ZA (1) ZA832584B (fr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4798830A (en) * 1982-04-15 1989-01-17 Research Corporation Platelet aggregation inhibitory agents and intermediates therefor
US4994462A (en) * 1982-04-15 1991-02-19 Research Corporation Platelet aggregation inhibitory agents and intermediate therefor
AT392783B (de) * 1987-10-08 1991-06-10 Warner Lambert Co Neue n-substituierte 3-piperidin- oder 3-tetrahydropyridincarbonsaeuren und derivate
JPH0623031U (ja) * 1992-08-25 1994-03-25 青山眼鏡株式会社 眼鏡セット
EP0869793A4 (fr) * 1995-11-13 1999-02-03 Smithkline Beecham Corp Composes hemoregulateurs
CN109824704B (zh) * 2019-03-15 2021-01-15 郑州轻工业学院 一种基于Evans-Showell型多酸的金属-有机配合物及其制备方法、应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2798070A (en) * 1954-02-04 1957-07-02 Mcneilab Inc Quaternary quinoline carboxamide salts and method of preparing same
NL289475A (fr) * 1962-03-01
SE431092B (sv) * 1979-07-10 1984-01-16 Thuresson Af Ekenstam Bo Terapeutiskt aktiva, substituerade piperidinkarboxianilider

Also Published As

Publication number Publication date
IE55561B1 (en) 1990-11-07
JPH0530828B2 (fr) 1993-05-11
EP0096735A3 (en) 1986-08-20
IL68423A (en) 1986-08-31
AU556925B2 (en) 1986-11-27
ES8602762A1 (es) 1985-12-16
ES535122A0 (es) 1985-12-16
AU1341183A (en) 1983-10-20
GR78182B (fr) 1984-09-26
JPS58192869A (ja) 1983-11-10
EP0096735B1 (fr) 1989-11-23
ZA832584B (en) 1983-12-28
ES8503347A1 (es) 1985-03-01
ES521794A0 (es) 1985-03-01
DE3380875D1 (en) 1989-12-28
US4443450A (en) 1984-04-17
DK163919B (da) 1992-04-21
IE830825L (en) 1983-10-15
DK167083D0 (da) 1983-04-15
EP0096735A2 (fr) 1983-12-28
DK167083A (da) 1983-10-16
CA1256438A (fr) 1989-06-27

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Legal Events

Date Code Title Description
B1 Patent granted (law 1993)
PBP Patent lapsed
PBP Patent lapsed