DK163661C - 2,5-pyrrolidindionderivater og farmaceutisk acceptable syreadditionssalte deraf - Google Patents

2,5-pyrrolidindionderivater og farmaceutisk acceptable syreadditionssalte deraf

Info

Publication number
DK163661C
DK163661C DK353785A DK353785A DK163661C DK 163661 C DK163661 C DK 163661C DK 353785 A DK353785 A DK 353785A DK 353785 A DK353785 A DK 353785A DK 163661 C DK163661 C DK 163661C
Authority
DK
Denmark
Prior art keywords
acid addition
addition salts
acceptable acid
indion
pyrrolide
Prior art date
Application number
DK353785A
Other languages
Danish (da)
English (en)
Other versions
DK163661B (da
DK353785D0 (da
DK353785A (da
Inventor
Bipinchandre Nanubhai Desai
Robert John Chorvat
Original Assignee
Searle & Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Searle & Co filed Critical Searle & Co
Publication of DK353785D0 publication Critical patent/DK353785D0/da
Publication of DK353785A publication Critical patent/DK353785A/da
Publication of DK163661B publication Critical patent/DK163661B/da
Application granted granted Critical
Publication of DK163661C publication Critical patent/DK163661C/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/34Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/36Oxygen or sulfur atoms
    • C07D207/402,5-Pyrrolidine-diones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/06Antiarrhythmics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/10Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with radicals containing only carbon and hydrogen atoms attached to ring carbon atoms
    • C07D211/14Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with radicals containing only carbon and hydrogen atoms attached to ring carbon atoms with hydrocarbon or substituted hydrocarbon radicals attached to the ring nitrogen atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/14Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D295/145Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Materials For Photolithography (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Lubricants (AREA)
  • Treatment Of Water By Ion Exchange (AREA)
  • Professional, Industrial, Or Sporting Protective Garments (AREA)
  • Suspension Of Electric Lines Or Cables (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
DK353785A 1984-08-03 1985-08-02 2,5-pyrrolidindionderivater og farmaceutisk acceptable syreadditionssalte deraf DK163661C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US63763384 1984-08-03
US06/637,633 US4554353A (en) 1984-08-03 1984-08-03 2,5-Pyrrolidinedione derivatives useful as antiarrhythmic agents

Publications (4)

Publication Number Publication Date
DK353785D0 DK353785D0 (da) 1985-08-02
DK353785A DK353785A (da) 1986-02-04
DK163661B DK163661B (da) 1992-03-23
DK163661C true DK163661C (da) 1992-08-24

Family

ID=24556766

Family Applications (1)

Application Number Title Priority Date Filing Date
DK353785A DK163661C (da) 1984-08-03 1985-08-02 2,5-pyrrolidindionderivater og farmaceutisk acceptable syreadditionssalte deraf

Country Status (18)

Country Link
US (1) US4554353A (fi)
EP (1) EP0170281B1 (fi)
JP (1) JPS6143164A (fi)
AT (1) ATE53575T1 (fi)
AU (1) AU581914B2 (fi)
CA (1) CA1270833C (fi)
DE (1) DE3578172D1 (fi)
DK (1) DK163661C (fi)
ES (1) ES8703421A1 (fi)
FI (1) FI80876C (fi)
GR (1) GR851890B (fi)
IE (1) IE60110B1 (fi)
IL (1) IL75985A (fi)
NO (1) NO166529C (fi)
NZ (1) NZ212955A (fi)
PH (1) PH20948A (fi)
PT (1) PT80905B (fi)
ZA (1) ZA855860B (fi)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
USD973876S1 (en) * 2020-03-18 2022-12-27 Stephen A. Young Blood sampling device

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH303078A (de) * 1951-09-11 1954-11-15 Ciba Geigy Verfahren zur Herstellung eines neuen Dioxopyrrolidins.
US2666060A (en) * 1951-09-11 1954-01-12 Ciba Pharm Prod Inc 1, 3-bisaminoalkyl-3-phenyl-2, 5-dioxopyrrolidines
FR1079802A (fr) * 1952-02-26 1954-12-02 Parke Davis & Co Fabrication de dérivés de la succinimide

Also Published As

Publication number Publication date
NO853069L (no) 1986-02-04
JPH0566942B2 (fi) 1993-09-22
GR851890B (fi) 1985-12-09
DK163661B (da) 1992-03-23
CA1270833A (en) 1990-06-26
FI852990L (fi) 1986-02-04
FI80876C (fi) 1990-08-10
JPS6143164A (ja) 1986-03-01
PT80905B (pt) 1987-09-30
AU581914B2 (en) 1989-03-09
US4554353A (en) 1985-11-19
NO166529C (no) 1991-08-07
EP0170281A2 (en) 1986-02-05
IL75985A0 (en) 1985-12-31
IL75985A (en) 1988-07-31
FI80876B (fi) 1990-04-30
FI852990A0 (fi) 1985-08-02
CA1270833C (en) 1990-06-26
IE60110B1 (en) 1994-06-01
DK353785D0 (da) 1985-08-02
AU4569385A (en) 1986-02-06
ES545870A0 (es) 1987-02-16
ES8703421A1 (es) 1987-02-16
DE3578172D1 (de) 1990-07-19
DK353785A (da) 1986-02-04
ZA855860B (en) 1986-10-29
EP0170281B1 (en) 1990-06-13
EP0170281A3 (en) 1986-06-25
ATE53575T1 (de) 1990-06-15
NZ212955A (en) 1988-03-30
IE851932L (en) 1986-02-03
NO166529B (no) 1991-04-29
PH20948A (en) 1987-06-10
PT80905A (en) 1985-09-01

Similar Documents

Publication Publication Date Title
SE8602723D0 (sv) Thiazoles, their production and pharmaceutical compositions containing them
FI901421A0 (fi) N-(3-hydroxi-4-piperidinyl) (dihydrobenzofuran, dihydro-2h-benzopyran- eller dihydrobenzodioxin) karboxiamidderivat.
NO871640D0 (no) Fremgangsmaate for fremstilling av n-(2[-aminofenyl)-benzamidderivater.
NO163331C (no) Analogifremgangsmaate til fremstilling av terapeutisk aktive 6,7-disubstituerte 1-cyklopropyl-1,4-dihydro-4-okso-1,8-naftyridin-3-karboksylsyrer.
AU581855B2 (en) 1-(4'-alkylsulphonylphenyl)-2-amino-1, 3-propanediol n-substituted derivatives
IL76345A0 (en) Proline derivatives and antihypertensive and anti-glaucoma pharmaceutical preparations containing the same
NO883520D0 (no) Fremgangsmaate for fremstilling av et injeksjonspreparat.
DK163661C (da) 2,5-pyrrolidindionderivater og farmaceutisk acceptable syreadditionssalte deraf
NO862390D0 (no) Fremgangsmaate for fremstilling av terapeutisk aktive 1,4-dihydropyridinderivater.
AU581856B2 (en) 1-(4'-alkylthiophenyl)-2-amino-1, 3-propanediol N-substituted derivatives
NO167801C (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive 2,2'-bi-1h-imidazolderivater.
FI894813A0 (fi) Menetelmä terapeuttisesti aktiivisten 2-metoksikarbonyylisubstituoitujen N,N'-di(trimetoksibentsoyyli)piperatsiinijohdannaisten valmistamiseksi
NO863005D0 (no) Fremgangsmaate for fremstilling av terapeutisk aktive 1,4,5,6,7,8-heksahydro-2-alkyl-4-aryl-5-okso-1,7-naftyridin-3-karboksylsyreesterderivater.
YU47871B (sh) Derivati aminokiselina
SU1319521A1 (ru) 5-(2,2,2-Трифтор-1-окси-1-трифторметилэтил)фурил-2-метилгидразонийбромид, проявляющий антимикробную и противовоспалительную активность

Legal Events

Date Code Title Description
PBP Patent lapsed