DK1633883T3 - Fremgangsmåde til analyse af LKB1-phosphoryleringsaktivitet - Google Patents
Fremgangsmåde til analyse af LKB1-phosphoryleringsaktivitetInfo
- Publication number
- DK1633883T3 DK1633883T3 DK04742944T DK04742944T DK1633883T3 DK 1633883 T3 DK1633883 T3 DK 1633883T3 DK 04742944 T DK04742944 T DK 04742944T DK 04742944 T DK04742944 T DK 04742944T DK 1633883 T3 DK1633883 T3 DK 1633883T3
- Authority
- DK
- Denmark
- Prior art keywords
- ampk
- lkb1
- analyzing
- substrate kinase
- phosphorylation
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/48—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving transferase
- C12Q1/485—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving transferase involving kinase
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/45—Transferases (2)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
- C12N9/1205—Phosphotransferases with an alcohol group as acceptor (2.7.1), e.g. protein kinases
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57484—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
- G01N33/57496—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites involving intracellular compounds
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Immunology (AREA)
- Pharmacology & Pharmacy (AREA)
- Molecular Biology (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Diabetes (AREA)
- Biomedical Technology (AREA)
- Zoology (AREA)
- Biochemistry (AREA)
- Wood Science & Technology (AREA)
- Cell Biology (AREA)
- Urology & Nephrology (AREA)
- Microbiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biotechnology (AREA)
- Analytical Chemistry (AREA)
- Genetics & Genomics (AREA)
- Physics & Mathematics (AREA)
- General Physics & Mathematics (AREA)
- Endocrinology (AREA)
- Pathology (AREA)
- General Engineering & Computer Science (AREA)
- Food Science & Technology (AREA)
- Obesity (AREA)
- Oncology (AREA)
- Biophysics (AREA)
- Hospice & Palliative Care (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US47910003P | 2003-06-17 | 2003-06-17 | |
GB0329866A GB2402938B (en) | 2003-06-17 | 2003-12-23 | Kinase assay |
PCT/GB2004/002584 WO2004113562A1 (en) | 2003-06-17 | 2004-06-17 | Method for assaying lkb1 phosphorylation activity |
Publications (1)
Publication Number | Publication Date |
---|---|
DK1633883T3 true DK1633883T3 (da) | 2009-01-26 |
Family
ID=33542697
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK04742944T DK1633883T3 (da) | 2003-06-17 | 2004-06-17 | Fremgangsmåde til analyse af LKB1-phosphoryleringsaktivitet |
Country Status (7)
Country | Link |
---|---|
EP (1) | EP1633883B1 (es) |
JP (1) | JP4651617B2 (es) |
AT (1) | ATE408023T1 (es) |
DE (1) | DE602004016503D1 (es) |
DK (1) | DK1633883T3 (es) |
ES (1) | ES2313029T3 (es) |
WO (1) | WO2004113562A1 (es) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20070036793A1 (en) * | 2003-07-17 | 2007-02-15 | Hardie David G | Methods for use of an lkb1/strad7mo25 complex |
US7439341B2 (en) | 2003-11-14 | 2008-10-21 | Integrated Dna Technologies, Inc. | Fluorescence quenching azo dyes, their methods of preparation and use |
JP5039565B2 (ja) * | 2005-02-16 | 2012-10-03 | エムディー バイオアルファ カンパニー リミテッド | 肥満、糖尿病、メタボリックシンドローム、神経変性疾患およびミトコンドリア機能不全関連疾患に伴う疾患を治療または予防するための医薬組成物 |
CA2601554A1 (en) * | 2005-05-20 | 2006-11-30 | Integrated Dna Technologies, Inc. | Compounds and methods for labeling oligonucleotides |
US9506057B2 (en) | 2010-03-26 | 2016-11-29 | Integrated Dna Technologies, Inc. | Modifications for antisense compounds |
JP5886828B2 (ja) | 2010-03-26 | 2016-03-16 | インテグレイテッド ディーエヌエイ テクノロジーズ インコーポレイテッド | 核酸のハイブリダイゼーションを強化する方法 |
WO2012033848A1 (en) | 2010-09-07 | 2012-03-15 | Integrated Dna Technologies, Inc. | Modifications for antisense compounds |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6800436B1 (en) * | 1997-11-27 | 2004-10-05 | Chugai Seiyaku Kabushiki Kaisha | Diagnostic method, diagnostic reagent and therapeutic preparation for diseases caused by variation in LKB1 gene |
EP1427425A4 (en) * | 2000-06-09 | 2006-04-05 | Univ Brigham Young | METHOD FOR THE TREATMENT OF OBESITAS AND MUSCULATOR FLUSHING AND ERGONIC TOOLS |
-
2004
- 2004-06-17 JP JP2006516430A patent/JP4651617B2/ja not_active Expired - Fee Related
- 2004-06-17 DK DK04742944T patent/DK1633883T3/da active
- 2004-06-17 DE DE602004016503T patent/DE602004016503D1/de not_active Expired - Lifetime
- 2004-06-17 AT AT04742944T patent/ATE408023T1/de not_active IP Right Cessation
- 2004-06-17 WO PCT/GB2004/002584 patent/WO2004113562A1/en active IP Right Grant
- 2004-06-17 ES ES04742944T patent/ES2313029T3/es not_active Expired - Lifetime
- 2004-06-17 EP EP04742944A patent/EP1633883B1/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
EP1633883A1 (en) | 2006-03-15 |
JP2007520199A (ja) | 2007-07-26 |
DE602004016503D1 (de) | 2008-10-23 |
JP4651617B2 (ja) | 2011-03-16 |
ATE408023T1 (de) | 2008-09-15 |
ES2313029T3 (es) | 2009-03-01 |
EP1633883B1 (en) | 2008-09-10 |
WO2004113562A1 (en) | 2004-12-29 |
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