DK1628989T3 - Hidtil ukendte, 14- og 15-leddet ring-forbindelser - Google Patents

Hidtil ukendte, 14- og 15-leddet ring-forbindelser

Info

Publication number
DK1628989T3
DK1628989T3 DK04732108T DK04732108T DK1628989T3 DK 1628989 T3 DK1628989 T3 DK 1628989T3 DK 04732108 T DK04732108 T DK 04732108T DK 04732108 T DK04732108 T DK 04732108T DK 1628989 T3 DK1628989 T3 DK 1628989T3
Authority
DK
Denmark
Prior art keywords
new
membered ring
ring connections
connections
membered
Prior art date
Application number
DK04732108T
Other languages
Danish (da)
English (en)
Inventor
Sulejman Alihodzic
John Michael Berge
Richard Lewis Jarvest
Original Assignee
Glaxo Group Ltd
Glaxosmithkline Zagreb
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB0310962A external-priority patent/GB0310962D0/en
Priority claimed from GB0407391A external-priority patent/GB0407391D0/en
Application filed by Glaxo Group Ltd, Glaxosmithkline Zagreb filed Critical Glaxo Group Ltd
Application granted granted Critical
Publication of DK1628989T3 publication Critical patent/DK1628989T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
DK04732108T 2003-05-13 2004-05-11 Hidtil ukendte, 14- og 15-leddet ring-forbindelser DK1628989T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB0310962A GB0310962D0 (en) 2003-05-13 2003-05-13 Novel compounds
GB0407391A GB0407391D0 (en) 2004-03-31 2004-03-31 Novel compounds
PCT/EP2004/005083 WO2004101587A1 (en) 2003-05-13 2004-05-11 Novel 14 and 15 memberred-ring compounds

Publications (1)

Publication Number Publication Date
DK1628989T3 true DK1628989T3 (da) 2007-10-08

Family

ID=33454579

Family Applications (1)

Application Number Title Priority Date Filing Date
DK04732108T DK1628989T3 (da) 2003-05-13 2004-05-11 Hidtil ukendte, 14- og 15-leddet ring-forbindelser

Country Status (15)

Country Link
US (1) US20070293472A1 (enExample)
EP (1) EP1628989B1 (enExample)
JP (1) JP2006528667A (enExample)
AR (1) AR044304A1 (enExample)
AT (1) ATE348837T1 (enExample)
CA (1) CA2525455A1 (enExample)
CL (1) CL2004001012A1 (enExample)
DE (1) DE602004003809T2 (enExample)
DK (1) DK1628989T3 (enExample)
ES (1) ES2278319T3 (enExample)
HR (1) HRP20070094T3 (enExample)
PL (1) PL1628989T3 (enExample)
PT (1) PT1628989E (enExample)
SI (1) SI1628989T1 (enExample)
WO (1) WO2004101587A1 (enExample)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7601695B2 (en) 2003-03-10 2009-10-13 Optimer Pharmaceuticals, Inc. Antibacterial agents
AU2005240849B2 (en) * 2004-05-06 2008-10-23 Glaxosmithkline Istrazivacki Centar Zagreb D.O.O. Ester linked macrolides useful for the treatment of microbial infections
GB0424961D0 (en) * 2004-11-11 2004-12-15 Glaxo Group Ltd Novel compounds
WO2007054295A1 (en) * 2005-11-09 2007-05-18 Glaxo Group Limited New 4*-substituted erythromycin derivative
GB0424958D0 (en) * 2004-11-11 2004-12-15 Glaxo Group Ltd Novel compounds
JP2008540503A (ja) 2005-05-10 2008-11-20 グラクソスミスクライン・イストラジヴァッキ・センタル・ザグレブ・ドルズバ・ゼー・オメイェノ・オドゴヴォルノスティオ 細菌感染症の処置に有用なエーテル結合マクロライド
WO2007054296A1 (en) * 2005-11-09 2007-05-18 Glaxo Group Limited Macrolones
AU2008316830B2 (en) 2007-10-25 2016-03-17 Cempra Pharmaceuticals, Inc. Process for the preparation of macrolide antibacterial agents
CN107854477A (zh) 2008-10-24 2018-03-30 森普拉制药公司 使用含三唑的大环内酯治疗抗性疾病的方法
US9937194B1 (en) 2009-06-12 2018-04-10 Cempra Pharmaceuticals, Inc. Compounds and methods for treating inflammatory diseases
US9480679B2 (en) 2009-09-10 2016-11-01 Cempra Pharmaceuticals, Inc. Methods for treating malaria, tuberculosis and MAC diseases
BR112012029586A2 (pt) * 2010-05-20 2016-08-02 Cempra Pharmaceuticals Inc processos para preparar macrolídeos e cetolídeos e intermediários dos mesmos
KR20130120458A (ko) 2010-09-10 2013-11-04 셈프라 파마슈티컬스, 인크. 질환을 치료하기 위한 수소결합 형성 플루오로 케토라이드
WO2013148891A1 (en) 2012-03-27 2013-10-03 Cempra Pharmaceuticals, Inc. Parenteral formulations for administering macrolide antibiotics
WO2014152326A1 (en) 2013-03-14 2014-09-25 Cempra Pharmaceuticals, Inc. Methods for treating respiratory diseases and formulations therefor
AU2014233240B2 (en) 2013-03-15 2018-08-09 Cempra Pharmaceuticals, Inc. Convergent processes for preparing macrolide antibacterial agents

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4180654A (en) * 1978-01-03 1979-12-25 Pfizer Inc. 4"-Deoxy-4"-acylamido derivatives of oleandomycin, erythromycin and erythromycin carbonate
US4512982A (en) * 1984-04-13 1985-04-23 Pfizer Inc. 9α-Aza-9α-homoerythromycin compounds, pharmaceutical composition and therapeutic method
US4686207A (en) * 1985-11-12 1987-08-11 Abbott Laboratories Erythromycin A 11,12-carbonates and method of use
IL93936A (en) * 1989-03-28 1994-06-24 Abbott Lab History of 9-dioxo-21,9-epoxy - erythromycin, method of preparation History of 11-oxo and 11-hydroxy, and pharmaceutical preparations containing them
WO1996034007A1 (es) * 1995-04-27 1996-10-31 Laboratorios Aranda, S.A. De C.V. Derivados de quinolonilcarboxieritromicina y composiciones farmaceuticas que los contienen
DE69723848T2 (de) * 1996-05-07 2004-07-01 Abbott Laboratories, Abbott Park 3-descladinose-2,3-anhydroerythromycin-derivate
EP0895999A1 (en) * 1997-08-06 1999-02-10 Pfizer Products Inc. C-4" substituted macrolide antibiotics
GB0025688D0 (en) * 2000-10-19 2000-12-06 Glaxo Group Ltd Macrolides
JP4311203B2 (ja) * 2001-08-08 2009-08-12 大正製薬株式会社 11a−アザライド化合物及びその製造方法
GB0127349D0 (en) * 2001-11-14 2002-01-02 Glaxo Group Ltd Macrolides
GB0225384D0 (en) * 2002-10-31 2002-12-11 Glaxo Group Ltd Novel compounds

Also Published As

Publication number Publication date
PL1628989T3 (pl) 2007-05-31
ES2278319T3 (es) 2007-08-01
PT1628989E (pt) 2007-03-30
DE602004003809D1 (de) 2007-02-01
ATE348837T1 (de) 2007-01-15
EP1628989A1 (en) 2006-03-01
HRP20070094T3 (hr) 2008-05-31
US20070293472A1 (en) 2007-12-20
EP1628989B1 (en) 2006-12-20
WO2004101587A1 (en) 2004-11-25
SI1628989T1 (sl) 2007-06-30
CA2525455A1 (en) 2004-11-25
DE602004003809T2 (de) 2007-10-11
AR044304A1 (es) 2005-09-07
CL2004001012A1 (es) 2005-03-18
JP2006528667A (ja) 2006-12-21

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