DK1622656T3 - Biomateriale - Google Patents
Biomateriale Download PDFInfo
- Publication number
- DK1622656T3 DK1622656T3 DK04731212.9T DK04731212T DK1622656T3 DK 1622656 T3 DK1622656 T3 DK 1622656T3 DK 04731212 T DK04731212 T DK 04731212T DK 1622656 T3 DK1622656 T3 DK 1622656T3
- Authority
- DK
- Denmark
- Prior art keywords
- biomaterial
- biomaterial according
- micropores
- ceramic
- macropores
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/56—Porous materials, e.g. foams or sponges
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/02—Inorganic materials
- A61L27/10—Ceramics or glasses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2400/00—Materials characterised by their function or physical properties
- A61L2400/18—Modification of implant surfaces in order to improve biocompatibility, cell growth, fixation of biomolecules, e.g. plasma treatment
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Transplantation (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Dermatology (AREA)
- Medicinal Chemistry (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Inorganic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Ceramic Engineering (AREA)
- Dispersion Chemistry (AREA)
- Materials For Medical Uses (AREA)
- Compositions Of Oxide Ceramics (AREA)
- Porous Artificial Stone Or Porous Ceramic Products (AREA)
Claims (14)
- - i - BIOMATERIALE1. Biomateriale omfattende et keramisk materiale, hvilket 5 keramisk materiale har en flerhed af forbundne mikroporer med en gennemsnitlig diameter på mellem 1 mm og 10 mm i alt væsentligt jævnt fordelt gennem det keramiske materiale og omfattende en flerhed af aflange makroporer med en gennemsnitlig diameter på mellem 150 mm og 500 mm og en 10 gennemsnitlig længde på mellem 300-3000 mm.
- 2. Biomateriale ifølge krav 1 sammensat af en flerhed af keramiske partikler, hvor hver partikel er delvis sammensmeltet med en eller flere tilstødende keramiske 15 partikler, så der dannes et gitter, der definerer mikroporerne.
- 3. Biomateriale ifølge krav 1 eller krav 2, hvori hver partikel har en gennemsnitlig diameter på 1 mm til 10 mm. 20
- 4. Biomateriale ifølge et hvilket som helst af de foregående krav med en gennemsnitlig porøsitet på mindst 50 %.
- 5. Biomateriale ifølge et hvilket som helst af de foregående krav med en trykstyrke på mindst 1,0 MPa.
- 6. Biomateriale ifølge et hvilket som helst af de foregående krav, hvori makroporerne er forbundet med 30 hinanden via en flerhed af mikroporer. - Δ -
- 7. Biomateriale ifølge et hvilket som helst af de foregående krav, hvori den gennemsnitlige tykkelse af det keramiske materiale mellem hver makropore er 20 til 200 mm.
- 8. Biomateriale ifølge et hvilket som helst af de foregående krav yderligere omfattende en flerhed af i alt væsentligt kugleformede midi-porer med en gennemsnitlig diameter på 5 mm til 150 mm.
- 9. Biomateriale ifølge et hvilket som helst af de foregående krav yderligere omfattende en eller flere biologisk eller farmaceutisk aktive forbindelser.
- 10. Biomateriale ifølge krav 9, hvori den farmaceutisk 15 aktive forbindelse er en cellevækstfaktor eller et knoglemorfogent protein.
- 11. Biomateriale ifølge et hvilket som helst af de foregående krav, hvori det keramiske materiale er mindst én 20 type calciumphosphat.
- 12. Biomateriale ifølge krav 11, hvori calciumphosphaten er ex- eller β-tricalciumphosphat eller hydroxyapatit eller en blanding deraf. 25
- 13. Knogleimplantat, dentalt implantat eller et øre-, næseeller hals- (ØNH)-implantat omfattende et biomateriale ifølge et hvilket som helst af kravene 1 til 12.
- 14. Biomateriale ifølge et hvilket som helst af kravene 1 til 12 til anvendelse som en knogleerstatning ved dental implantation eller materiale til kæbe-ansigts-reparation.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB0311221.6A GB0311221D0 (en) | 2003-05-15 | 2003-05-15 | Biomaterial |
PCT/GB2004/001946 WO2004101013A1 (en) | 2003-05-15 | 2004-05-05 | Biomaterial |
Publications (1)
Publication Number | Publication Date |
---|---|
DK1622656T3 true DK1622656T3 (da) | 2016-08-22 |
Family
ID=9958162
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK04731212.9T DK1622656T3 (da) | 2003-05-15 | 2004-05-05 | Biomateriale |
Country Status (7)
Country | Link |
---|---|
US (1) | US8288452B2 (da) |
EP (1) | EP1622656B8 (da) |
CA (1) | CA2524982C (da) |
DK (1) | DK1622656T3 (da) |
ES (1) | ES2584187T3 (da) |
GB (1) | GB0311221D0 (da) |
WO (1) | WO2004101013A1 (da) |
Families Citing this family (24)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8282678B2 (en) | 2002-11-13 | 2012-10-09 | Allium Medical Solutions Ltd. | Endoluminal lining |
FR2850282B1 (fr) | 2003-01-27 | 2007-04-06 | Jerome Asius | Implant injectable a base de ceramique pour le comblement de rides, depressions cutanees et cicatrices, et sa preparation |
AU2005212339B2 (en) | 2004-02-06 | 2010-11-25 | Georgia Tech Research Corporation | Load bearing biocompatible device |
CA2558623C (en) | 2004-02-06 | 2013-04-16 | Georgia Tech Research Corporation | Surface directed cellular attachment |
GB0502493D0 (en) * | 2005-02-07 | 2005-03-16 | Orthogem Ltd | Bone cement |
US7531190B2 (en) * | 2005-05-25 | 2009-05-12 | Biomet Manufacturing Corp. | Porous ceramic structure containing biologics |
WO2007030616A2 (en) | 2005-09-09 | 2007-03-15 | Wright Medical Technology, Inc. | Composite bone graft substitute cement and articles produced therefrom |
WO2007056185A2 (en) * | 2005-11-04 | 2007-05-18 | Ceramatec, Inc. | Process of making ceramic, mineral and metal beads from powder |
US20070254798A1 (en) * | 2006-03-31 | 2007-11-01 | Addiego William P | Peroxide containing compounds as pore formers in the manufacture of ceramic articles |
GB0610333D0 (en) * | 2006-05-24 | 2006-07-05 | Orthogem Ltd | Bone repair or augmentation device |
NL1032851C2 (nl) * | 2006-11-10 | 2008-05-14 | Fondel Finance B V | Kit en werkwijze voor het fixeren van een prothese of deel daarvan en/of het vullen van benige defecten. |
CA2689675A1 (en) * | 2007-02-07 | 2008-08-14 | Mcgill University | Bioceramic implants having bioactive substance |
US20080293927A1 (en) * | 2007-05-21 | 2008-11-27 | The Xim Group, Llc | Method for preparing pelleted lignocellulosic ion exchange materials |
US8066770B2 (en) * | 2007-05-31 | 2011-11-29 | Depuy Products, Inc. | Sintered coatings for implantable prostheses |
JP2010528765A (ja) * | 2007-06-07 | 2010-08-26 | スミス アンド ネフュー インコーポレーテッド | 医用インプラント用途のための網状粒子多孔質被覆 |
JP2011509157A (ja) * | 2008-01-09 | 2011-03-24 | イノベイテイブ ヘルス テクノロジーズ エルエルシー | 骨造成および保存のためのインプラントペレットおよび方法 |
GB0912855D0 (en) | 2009-07-23 | 2009-08-26 | Orthogem Ltd | Composite delivery device |
WO2011022642A1 (en) * | 2009-08-21 | 2011-02-24 | Malshe Ajay P | Nanostructured hydroxyapatite coating for dental and orthopedic implants |
WO2012162552A1 (en) | 2011-05-26 | 2012-11-29 | Cartiva, Inc. | Tapered joint implant and related tools |
US9642935B1 (en) * | 2012-01-27 | 2017-05-09 | Robert L. Bundy | Synthetic, composite osteogenic bone graft |
EP3034033A1 (en) | 2014-12-16 | 2016-06-22 | Nobel Biocare Services AG | Dental implant |
WO2016161025A1 (en) | 2015-03-31 | 2016-10-06 | Cartiva, Inc. | Hydrogel implants with porous materials and methods |
WO2016161026A1 (en) | 2015-03-31 | 2016-10-06 | Cartiva, Inc. | Carpometacarpal (cmc) implants and methods |
AU2016248062B2 (en) | 2015-04-14 | 2020-01-23 | Cartiva, Inc. | Tooling for creating tapered opening in tissue and related methods |
Family Cites Families (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5705118A (en) * | 1992-08-27 | 1998-01-06 | Polyceramics, Inc. | Process for producing a ceramic body |
US6376573B1 (en) * | 1994-12-21 | 2002-04-23 | Interpore International | Porous biomaterials and methods for their manufacture |
US6846493B2 (en) * | 1995-09-01 | 2005-01-25 | Millenium Biologix Inc. | Synthetic biomaterial compound of calcium phosphate phases particularly adapted for supporting bone cell activity |
AU1673797A (en) * | 1996-02-20 | 1997-09-10 | Mikuni Corporation | Method for producing granulated material |
US6472210B1 (en) * | 1997-11-14 | 2002-10-29 | Bonetec Corporation | Polymer scaffold having microporous polymer struts defining interconnected macropores |
CA2221195A1 (en) * | 1997-11-14 | 1999-05-14 | Chantal E. Holy | Biodegradable polymer matrix |
KR100652511B1 (ko) * | 1998-01-29 | 2006-11-30 | 밀레늄 바이올로직스 인코포레이티드 | 합성 생체 물질 화합물 |
AU766735B2 (en) * | 1998-09-15 | 2003-10-23 | Isotis N.V. | Osteoinduction |
AU1916200A (en) * | 1998-11-20 | 2000-06-13 | Board Of Trustees Of Michigan State University | Porous ceramic composites |
US6605648B1 (en) * | 1999-04-06 | 2003-08-12 | Phillips Plastics Corporation | Sinterable structures and method |
AU778651B2 (en) * | 1999-12-16 | 2004-12-16 | Isotis N.V. | Porous ceramic body |
WO2002011781A1 (en) | 2000-08-04 | 2002-02-14 | Orthogem Limited | Porous synthetic bone graft and method of manufacture thereof |
GB0020610D0 (en) * | 2000-08-21 | 2000-10-11 | Dytech Corp Ltd | Uses of porous carriers |
US6626950B2 (en) * | 2001-06-28 | 2003-09-30 | Ethicon, Inc. | Composite scaffold with post anchor for the repair and regeneration of tissue |
US20050119742A1 (en) * | 2001-06-30 | 2005-06-02 | Richter Paul W. | Orbital implant |
US7875342B2 (en) * | 2001-09-24 | 2011-01-25 | Warsaw Orthopedic, Inc. | Porous ceramic composite bone grafts |
-
2003
- 2003-05-15 GB GBGB0311221.6A patent/GB0311221D0/en not_active Ceased
-
2004
- 2004-05-05 WO PCT/GB2004/001946 patent/WO2004101013A1/en active Application Filing
- 2004-05-05 ES ES04731212.9T patent/ES2584187T3/es not_active Expired - Lifetime
- 2004-05-05 EP EP04731212.9A patent/EP1622656B8/en not_active Expired - Lifetime
- 2004-05-05 DK DK04731212.9T patent/DK1622656T3/da active
- 2004-05-05 CA CA2524982A patent/CA2524982C/en not_active Expired - Fee Related
-
2005
- 2005-11-15 US US11/273,927 patent/US8288452B2/en active Active
Also Published As
Publication number | Publication date |
---|---|
ES2584187T3 (es) | 2016-09-26 |
CA2524982A1 (en) | 2004-11-25 |
EP1622656A1 (en) | 2006-02-08 |
EP1622656B8 (en) | 2016-09-14 |
WO2004101013A1 (en) | 2004-11-25 |
EP1622656B1 (en) | 2016-07-13 |
CA2524982C (en) | 2013-07-30 |
US20060122706A1 (en) | 2006-06-08 |
US8288452B2 (en) | 2012-10-16 |
GB0311221D0 (en) | 2003-06-18 |
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