DK1611083T3 - Syntese af 2-chlormethyl-6-methylbenzoesyreestere - Google Patents

Syntese af 2-chlormethyl-6-methylbenzoesyreestere

Info

Publication number
DK1611083T3
DK1611083T3 DK04719953T DK04719953T DK1611083T3 DK 1611083 T3 DK1611083 T3 DK 1611083T3 DK 04719953 T DK04719953 T DK 04719953T DK 04719953 T DK04719953 T DK 04719953T DK 1611083 T3 DK1611083 T3 DK 1611083T3
Authority
DK
Denmark
Prior art keywords
chloromethyl
synthesis
acid esters
methylbenzoic acid
methylbenzoic
Prior art date
Application number
DK04719953T
Other languages
English (en)
Inventor
Claus-Juergen Maier
Tobias Metzenthin
Joachim Graeser
Richard Bicker
Javier Manero
Original Assignee
Sanofi Aventis Deutschland
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Aventis Deutschland filed Critical Sanofi Aventis Deutschland
Application granted granted Critical
Publication of DK1611083T3 publication Critical patent/DK1611083T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D263/00Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/30Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D263/32Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/48Drugs for disorders of the endocrine system of the pancreatic hormones
    • A61P5/50Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00Preparation of carboxylic acid esters
    • C07C67/30Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group
    • C07C67/307Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by introduction of halogen; by substitution of halogen atoms by other halogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/76Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
DK04719953T 2003-03-25 2004-03-12 Syntese af 2-chlormethyl-6-methylbenzoesyreestere DK1611083T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10313228A DE10313228A1 (de) 2003-03-25 2003-03-25 Synthese von 2-Chlormethyl-6-methylbenzoesäureestern
PCT/EP2004/002579 WO2004085377A1 (de) 2003-03-25 2004-03-12 Synthese von 2-chlormethyl-6-methylbenzoesäureestern

Publications (1)

Publication Number Publication Date
DK1611083T3 true DK1611083T3 (da) 2008-01-21

Family

ID=33015963

Family Applications (1)

Application Number Title Priority Date Filing Date
DK04719953T DK1611083T3 (da) 2003-03-25 2004-03-12 Syntese af 2-chlormethyl-6-methylbenzoesyreestere

Country Status (25)

Country Link
EP (1) EP1611083B1 (da)
JP (1) JP4510805B2 (da)
KR (1) KR20050116388A (da)
CN (1) CN100378065C (da)
AR (1) AR043752A1 (da)
AT (1) ATE374742T1 (da)
AU (1) AU2004224177B2 (da)
BR (1) BRPI0408653A (da)
CA (1) CA2519715A1 (da)
CO (1) CO5690546A2 (da)
CY (1) CY1107029T1 (da)
DE (2) DE10313228A1 (da)
DK (1) DK1611083T3 (da)
ES (1) ES2293237T3 (da)
HK (1) HK1087098A1 (da)
IL (1) IL171031A (da)
MX (1) MXPA05010001A (da)
NO (1) NO20054875L (da)
NZ (1) NZ542603A (da)
PL (1) PL1611083T3 (da)
PT (1) PT1611083E (da)
RU (1) RU2345982C2 (da)
TW (1) TW200502213A (da)
WO (1) WO2004085377A1 (da)
ZA (1) ZA200506499B (da)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102005029382B3 (de) 2005-06-24 2006-12-21 Sanofi-Aventis Deutschland Gmbh Alkoxymethylyl-substituierte Benzoesäurederivate, Verfahren zu ihrer Herstellung und ihre Anwendung als Arzneimittel
CN114805120A (zh) * 2022-05-23 2022-07-29 江苏瑞达环保科技有限公司 一种间氰甲基苯甲酸甲酯的合成工艺

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4689425A (en) * 1986-11-06 1987-08-25 Stauffer Chemical Company Photochlorination of aromatic compounds in the side chain
JP2002543065A (ja) * 1999-04-28 2002-12-17 アベンティス・ファーマ・ドイチユラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング Ppap受容体リガンドとしてのトリアリール酸誘導体
HUP0201291A3 (en) * 1999-04-28 2002-11-28 Sanofi Aventis Deutschland Di-aryl acid derivatives as ppar receptor ligands and pharmaceutical compositions containing them
IL160556A0 (en) * 2001-08-31 2004-07-25 Aventis Pharma Gmbh Diaryl cycloalkyl derivatives, method for producing the same and the use thereof as ppar activators

Also Published As

Publication number Publication date
NO20054875D0 (no) 2005-10-21
NO20054875L (no) 2005-12-27
IL171031A (en) 2010-11-30
EP1611083A1 (de) 2006-01-04
EP1611083B1 (de) 2007-10-03
ES2293237T3 (es) 2008-03-16
CN1759092A (zh) 2006-04-12
ZA200506499B (en) 2006-07-26
ATE374742T1 (de) 2007-10-15
JP2006521307A (ja) 2006-09-21
MXPA05010001A (es) 2005-11-17
AU2004224177A1 (en) 2004-10-07
KR20050116388A (ko) 2005-12-12
CA2519715A1 (en) 2004-10-07
JP4510805B2 (ja) 2010-07-28
CN100378065C (zh) 2008-04-02
DE10313228A1 (de) 2004-10-21
RU2345982C2 (ru) 2009-02-10
TW200502213A (en) 2005-01-16
CO5690546A2 (es) 2006-10-31
PT1611083E (pt) 2007-11-26
NZ542603A (en) 2007-12-21
RU2005132827A (ru) 2006-02-10
HK1087098A1 (en) 2006-10-06
CY1107029T1 (el) 2012-09-26
AR043752A1 (es) 2005-08-10
BRPI0408653A (pt) 2006-03-07
PL1611083T3 (pl) 2008-01-31
AU2004224177B2 (en) 2010-01-21
WO2004085377A1 (de) 2004-10-07
DE502004005137D1 (en) 2007-11-15

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