GB2213058B
(en)
*
|
1987-12-03 |
1991-07-17 |
Reckitt & Colmann Prod Ltd |
Compositions comprising buprenorphine and naltrexone for treatment of opiate addicts
|
GB8728294D0
(en)
*
|
1987-12-03 |
1988-01-06 |
Reckitt & Colmann Prod Ltd |
Treatment compositions
|
US5236714A
(en)
*
|
1988-11-01 |
1993-08-17 |
Alza Corporation |
Abusable substance dosage form having reduced abuse potential
|
US5272149A
(en)
*
|
1992-05-05 |
1993-12-21 |
Stalling Reginald W |
Symptom controlled receptor substitution for addiction withdrawl
|
US6096756A
(en)
|
1992-09-21 |
2000-08-01 |
Albert Einstein College Of Medicine Of Yeshiva University |
Method of simultaneously enhancing analgesic potency and attenuating dependence liability caused by morphine and other bimodally-acting opioid agonists
|
US5512578A
(en)
*
|
1992-09-21 |
1996-04-30 |
Albert Einstein College Of Medicine Of Yeshiva University, A Division Of Yeshiva University |
Method of simultaneously enhancing analgesic potency and attenuating dependence liability caused by exogenous and endogenous opiod agonists
|
DE19652188C2
(de)
*
|
1996-12-16 |
2002-02-14 |
Lohmann Therapie Syst Lts |
Flache Arzneizubereitung zur Applikation und Freisetzung von Buprenorphin oder einer pharmakologisch vergleichbaren Substanz in der Mundhöhle und Verfahren zu ihrer Herstellung
|
US5968547A
(en)
*
|
1997-02-24 |
1999-10-19 |
Euro-Celtique, S.A. |
Method of providing sustained analgesia with buprenorphine
|
US7220737B1
(en)
|
1997-09-04 |
2007-05-22 |
Novoneuron, Inc |
Noribogaine in the treatment of pain and drug addiction
|
IL134796A0
(en)
*
|
1997-09-04 |
2001-04-30 |
Novoneuron Inc |
Noribogaine in the treatment of pain and drug addiction
|
US6375957B1
(en)
|
1997-12-22 |
2002-04-23 |
Euro-Celtique, S.A. |
Opioid agonist/opioid antagonist/acetaminophen combinations
|
DE69834268T2
(de)
*
|
1997-12-22 |
2007-04-12 |
Euro-Celtique S.A. |
Peroral zu verabreichende Arzneiform enthaltend eine Kombination von einem Opioid Agonisten und Naltrexon
|
IL136805A0
(en)
|
1997-12-22 |
2001-11-25 |
Euro Celtique Sa |
A method of preventing abuse of opioid dosage forms
|
EP0984276A4
(en)
*
|
1998-02-16 |
2003-08-27 |
Inst Physical & Chem Res |
CAPILLARY CASSETTE AND METHOD FOR THE PRODUCTION THEREOF
|
US6007841A
(en)
*
|
1998-03-13 |
1999-12-28 |
Algos Pharmaceutical Corporation |
Analgesic composition and method for treating pain
|
US6849263B2
(en)
*
|
1998-12-21 |
2005-02-01 |
Generex Pharmaceutical Incorporated |
Pharmaceutical compositions for buccal delivery of pain relief medications
|
US7087215B2
(en)
*
|
1998-12-21 |
2006-08-08 |
Generex Pharmaceuticals Incorporated |
Methods of administering and enhancing absorption of pharmaceutical agents
|
IL148343A0
(en)
*
|
1999-08-27 |
2002-09-12 |
Southern Res Inst |
Injectable buprenorphine microparticle compositions and their use
|
RU2147880C1
(ru)
*
|
1999-11-10 |
2000-04-27 |
Мамренко Валерий Русланович |
Лекарственное средство для лечения пациентов с хроническим алкоголизмом и способ их лечения
|
AR031682A1
(es)
*
|
1999-11-19 |
2003-10-01 |
Reckitt Benckiser Helthcare Uk |
Composiciones farmaceuticas
|
DK2517710T3
(en)
|
2000-02-08 |
2015-05-26 |
Euro Celtique Sa |
Oral opioid agonist formulations secured against forgery
|
US6716449B2
(en)
|
2000-02-08 |
2004-04-06 |
Euro-Celtique S.A. |
Controlled-release compositions containing opioid agonist and antagonist
|
CA2446550C
(en)
|
2001-05-11 |
2012-03-06 |
Endo Pharmaceuticals, Inc. |
Abuse-resistant controlled-release opioid dosage form
|
US20030035839A1
(en)
*
|
2001-05-15 |
2003-02-20 |
Peirce Management, Llc |
Pharmaceutical composition for both intraoral and oral administration
|
AU2002314967B2
(en)
*
|
2001-06-05 |
2007-09-20 |
University Of Chicago |
Use of methylnaltrexone to treat immune suppression
|
JP2005520778A
(ja)
*
|
2001-07-06 |
2005-07-14 |
エンドー ファーマシューティカルズ, インコーポレイティド |
鎮痛薬として使用するための6−ヒドロキシ−オキシモルホンの非経口投与
|
DE60223254T2
(de)
*
|
2001-07-06 |
2008-08-14 |
Penwest Pharmaceuticals Co. |
Verzögert freisetzende formulierungen von oxymorphon
|
US8329216B2
(en)
*
|
2001-07-06 |
2012-12-11 |
Endo Pharmaceuticals Inc. |
Oxymorphone controlled release formulations
|
MXPA04000584A
(es)
*
|
2001-07-18 |
2004-04-20 |
Euro Celtique Sa |
COMBINACIONES FARMACeUTICAS DE OXICODONA Y NALOXONA.
|
US20030044458A1
(en)
|
2001-08-06 |
2003-03-06 |
Curtis Wright |
Oral dosage form comprising a therapeutic agent and an adverse-effect agent
|
US20030068375A1
(en)
|
2001-08-06 |
2003-04-10 |
Curtis Wright |
Pharmaceutical formulation containing gelling agent
|
US20030157168A1
(en)
|
2001-08-06 |
2003-08-21 |
Christopher Breder |
Sequestered antagonist formulations
|
EP1414451B1
(en)
|
2001-08-06 |
2009-05-20 |
Euro-Celtique S.A. |
Opioid agonist formulations with releasable and sequestered antagonist
|
US20030091635A1
(en)
*
|
2001-09-26 |
2003-05-15 |
Baichwal Anand R. |
Opioid formulations having reduced potential for abuse
|
US6863901B2
(en)
*
|
2001-11-30 |
2005-03-08 |
Collegium Pharmaceutical, Inc. |
Pharmaceutical composition for compressed annular tablet with molded triturate tablet for both intraoral and oral administration
|
US6827946B2
(en)
*
|
2001-12-05 |
2004-12-07 |
Collegium Pharmaceutical, Inc. |
Compositions containing both sedative and non-sedative antihistamines
|
EP1639997A1
(en)
|
2002-04-05 |
2006-03-29 |
Euro-Celtique S.A. |
Matrix for sustained, invariant and independant release of active compounds
|
EP1509182A4
(en)
*
|
2002-05-31 |
2009-12-30 |
Titan Pharmaceuticals Inc |
IMPLANTABLE POLYMERS DEVICE FOR THE DELAYED RELEASE OF BUPRENORPHINE
|
PT1551372T
(pt)
*
|
2002-09-20 |
2018-07-23 |
Alpharma Pharmaceuticals Llc |
Subunidade de sequestração e composições e métodos relacionados
|
DE602004024963D1
(de)
*
|
2003-03-13 |
2010-02-25 |
Controlled Chemicals Inc |
Oxycodon- konjugate mit niedrigerem missbrauch- potential und ausgedehnter tätigkeitsdauer
|
CA2520613C
(en)
|
2003-03-31 |
2012-12-04 |
Titan Pharmaceuticals, Inc. |
Implantable polymeric device for sustained release of dopamine agonist
|
US20040202717A1
(en)
*
|
2003-04-08 |
2004-10-14 |
Mehta Atul M. |
Abuse-resistant oral dosage forms and method of use thereof
|
TWI347201B
(en)
*
|
2003-04-21 |
2011-08-21 |
Euro Celtique Sa |
Pharmaceutical products,uses thereof and methods for preparing the same
|
EP1604666A1
(en)
*
|
2004-06-08 |
2005-12-14 |
Euro-Celtique S.A. |
Opioids for the treatment of the Chronic Obstructive Pulmonary Disease (COPD)
|
CA2569958C
(en)
|
2004-06-12 |
2016-03-22 |
Jane C. Hirsh |
Abuse-deterrent drug formulations
|
EP1702558A1
(en)
*
|
2005-02-28 |
2006-09-20 |
Euro-Celtique S.A. |
Method and device for the assessment of bowel function
|
US7568409B2
(en)
*
|
2005-03-30 |
2009-08-04 |
Federal-Mogul World Wide, Inc |
Hybrid orbiting spindle for shaping non-circular holes
|
ZA200807571B
(en)
|
2006-03-01 |
2009-08-26 |
Ethypharm Sa |
Crush-resistant tablets intended to prevent accidental misuse and unlawful diversion
|
US20070212414A1
(en)
*
|
2006-03-08 |
2007-09-13 |
Penwest Pharmaceuticals Co. |
Ethanol-resistant sustained release formulations
|
CN101677963B
(zh)
|
2006-06-19 |
2012-05-30 |
奥尔制药公司 |
药物组合物
|
EP1897543A1
(en)
*
|
2006-08-30 |
2008-03-12 |
Euro-Celtique S.A. |
Buprenorphine- wafer for drug substitution therapy
|
PL2101740T3
(pl)
|
2006-12-04 |
2014-04-30 |
Orexo Ab |
Nowa, niepodatna na nadużycie kompozycja farmaceutyczna zawierająca opioidy
|
US20080199407A1
(en)
|
2007-02-15 |
2008-08-21 |
Slater Kenneth C |
Drug Detoxification Protocol Using Microdosing
|
EP2120945A1
(en)
*
|
2007-02-28 |
2009-11-25 |
Collegium Pharmaceutical, Inc. |
Antihistamine combination
|
GB2447014A
(en)
|
2007-03-01 |
2008-09-03 |
Reckitt Benckiser Healthcare |
Analgesic composition comprising a specific ratio of buprenorphine and naltrexone
|
US20090124650A1
(en)
*
|
2007-06-21 |
2009-05-14 |
Endo Pharmaceuticals, Inc. |
Method of Treating Pain Utilizing Controlled Release Oxymorphone Pharmaceutical Compositions and Instructions on Effects of Alcohol
|
US8623418B2
(en)
*
|
2007-12-17 |
2014-01-07 |
Alpharma Pharmaceuticals Llc |
Pharmaceutical composition
|
US20100151014A1
(en)
*
|
2008-12-16 |
2010-06-17 |
Alpharma Pharmaceuticals, Llc |
Pharmaceutical composition
|
US20100266645A1
(en)
*
|
2007-12-17 |
2010-10-21 |
Alfred Liang |
Pharmaceutical compositions
|
EP2317991B1
(en)
*
|
2008-07-07 |
2017-05-03 |
Euro-Celtique S.A. |
Use of opioid antagonists for treating urinary retention
|
KR20140141727A
(ko)
|
2009-03-10 |
2014-12-10 |
유로-셀티큐 에스.에이. |
옥시코돈 및 날록손을 포함하는 즉시 방출 제약 조성물
|
US8475832B2
(en)
|
2009-08-07 |
2013-07-02 |
Rb Pharmaceuticals Limited |
Sublingual and buccal film compositions
|
US10668060B2
(en)
|
2009-12-10 |
2020-06-02 |
Collegium Pharmaceutical, Inc. |
Tamper-resistant pharmaceutical compositions of opioids and other drugs
|
US8765737B1
(en)
|
2010-05-11 |
2014-07-01 |
Demerx, Inc. |
Methods and compositions for preparing and purifying noribogaine
|
US9394294B2
(en)
|
2010-05-11 |
2016-07-19 |
Demerx, Inc. |
Methods and compositions for preparing and purifying noribogaine
|
US8362007B1
(en)
|
2010-05-11 |
2013-01-29 |
Demerx, Inc. |
Substituted noribogaine
|
US8741891B1
(en)
|
2010-06-22 |
2014-06-03 |
Demerx, Inc. |
N-substituted noribogaine prodrugs
|
US8802832B2
(en)
|
2010-06-22 |
2014-08-12 |
Demerx, Inc. |
Compositions comprising noribogaine and an excipient to facilitate transport across the blood brain barrier
|
US8637648B1
(en)
|
2010-06-22 |
2014-01-28 |
Demerx, Inc. |
Compositions comprising noribogaine and an excipient to facilitate transport across the blood brain barrier
|
US9586954B2
(en)
|
2010-06-22 |
2017-03-07 |
Demerx, Inc. |
N-substituted noribogaine prodrugs
|
UA111065C2
(uk)
|
2010-07-23 |
2016-03-25 |
Демеркс, Інк. |
Композиції норибогаїну
|
EP2481740B1
(en)
|
2011-01-26 |
2015-11-04 |
DemeRx, Inc. |
Methods and compositions for preparing noribogaine from voacangine
|
US9617274B1
(en)
|
2011-08-26 |
2017-04-11 |
Demerx, Inc. |
Synthetic noribogaine
|
SMT202100546T1
(it)
|
2011-09-19 |
2021-11-12 |
Orexo Ab |
Compresse per via sublinguale resistenti all'abuso comprendenti buprenorfina e naloxone
|
CA2855994A1
(en)
|
2011-12-09 |
2013-06-13 |
Demerx, Inc. |
Phosphate esters of noribogaine
|
US9211293B2
(en)
*
|
2011-12-15 |
2015-12-15 |
Alkermes Pharma Ireland Limited |
Opioid agonist antagonist combinations
|
US9150584B2
(en)
|
2012-01-25 |
2015-10-06 |
Demerx, Inc. |
Indole and benzofuran fused isoquinuclidene derivatives and processes for preparing them
|
WO2013112673A1
(en)
|
2012-01-25 |
2013-08-01 |
Demerx, Inc. |
Synthetic voacangine
|
US8940728B2
(en)
|
2012-12-20 |
2015-01-27 |
Demerx, Inc. |
Substituted noribogaine
|
WO2014098877A1
(en)
|
2012-12-20 |
2014-06-26 |
Demerx, Inc. |
Substituted noribogaine
|
US9045481B2
(en)
|
2012-12-20 |
2015-06-02 |
Demerx, Inc. |
Substituted noribogaine
|
JP2016525138A
(ja)
|
2013-07-23 |
2016-08-22 |
ユーロ−セルティーク エス.エイ. |
疼痛および腸内ディスバイオシスをもたらす疾患および/または腸内細菌移行に対するリスクを高める疾患に罹患している患者における痛みの治療への使用のためのオキシコドンおよびナロキソンの組み合わせ
|
CA2989550C
(en)
|
2014-06-18 |
2023-08-08 |
Demerx, Inc. |
Halogenated indole and benzofuran derivatives of isoquinuclidene and processes for preparing them
|
CA2998147A1
(en)
*
|
2015-09-09 |
2017-03-16 |
Biodelivery Sciences International, Inc. |
Methods of safely transitioning a subject to buprenorphine
|
WO2017222575A1
(en)
|
2016-06-23 |
2017-12-28 |
Collegium Pharmaceutical, Inc. |
Process of making more stable abuse-deterrent oral formulations
|
WO2019099679A1
(en)
|
2017-11-15 |
2019-05-23 |
The Regents Of The University Of California |
Treatment of opioid use disorder, opioid withdrawal symptoms, and chronic pain
|