DK160557C - 1,8-naphthyridinforbindelser og farmaceutiske praeparater indeholdende saadanne - Google Patents
1,8-naphthyridinforbindelser og farmaceutiske praeparater indeholdende saadanneInfo
- Publication number
- DK160557C DK160557C DK264784A DK264784A DK160557C DK 160557 C DK160557 C DK 160557C DK 264784 A DK264784 A DK 264784A DK 264784 A DK264784 A DK 264784A DK 160557 C DK160557 C DK 160557C
- Authority
- DK
- Denmark
- Prior art keywords
- naphthyride
- compounds
- products
- pharmaceutical preparations
- preparations containing
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
- C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D241/14—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D241/24—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
- C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D241/14—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D241/24—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D241/26—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with nitrogen atoms directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
- C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
- C07D407/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/12—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
- C07D491/14—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
- C07D495/14—Ortho-condensed systems
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Pulmonology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US49958483A | 1983-05-31 | 1983-05-31 | |
US49958483 | 1983-05-31 | ||
US06/597,887 US4680298A (en) | 1983-05-31 | 1984-04-09 | Tricyclic anti-allergy and use as anti-inflammatory agents |
US59788784 | 1984-04-09 |
Publications (4)
Publication Number | Publication Date |
---|---|
DK264784D0 DK264784D0 (da) | 1984-05-29 |
DK264784A DK264784A (da) | 1984-12-01 |
DK160557B DK160557B (da) | 1991-03-25 |
DK160557C true DK160557C (da) | 1991-09-09 |
Family
ID=27053194
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK264784A DK160557C (da) | 1983-05-31 | 1984-05-29 | 1,8-naphthyridinforbindelser og farmaceutiske praeparater indeholdende saadanne |
Country Status (14)
Country | Link |
---|---|
US (1) | US4680298A (fr) |
EP (1) | EP0127135B1 (fr) |
JP (1) | JPH0747590B2 (fr) |
AU (1) | AU559754B2 (fr) |
CA (1) | CA1251208A (fr) |
DE (1) | DE3483064D1 (fr) |
DK (1) | DK160557C (fr) |
GB (1) | GB2142013B (fr) |
GR (1) | GR81552B (fr) |
HK (1) | HK8092A (fr) |
IL (1) | IL71960A (fr) |
NZ (1) | NZ208310A (fr) |
PH (1) | PH22970A (fr) |
SG (1) | SG83890G (fr) |
Families Citing this family (35)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DK127086A (da) * | 1985-03-25 | 1986-09-26 | Schering Corp | Substituerede 1,8-naphthyridoner, fremgangsmaader til deres fremstilling og farmaceutiske kompositioner, der indeholder disse forbindelser |
US4596809A (en) * | 1985-03-25 | 1986-06-24 | Schering Corporation | Substituted 1,8-naphthyridinones, useful as anti-allergic agents |
IL79110A0 (en) | 1985-06-13 | 1986-09-30 | Schering Corp | Polycyclic quinoline,naphthyridine and pyrazinopyridine derivatives |
US4810708A (en) * | 1986-05-15 | 1989-03-07 | Schering Corporation | Polycyclic quinoline, naphthyridine and pyrazinopyridine derivatives |
US4988705A (en) * | 1985-06-13 | 1991-01-29 | Schering Corporation | Polycyclic quinoline, naphthyridine and pyrazinopyridine derivatives |
US5116840A (en) * | 1985-06-13 | 1992-05-26 | Schering Corporation | Polycyclic quinoline, naphthyridine and pyrazinopyridine derivatives |
DE3669656D1 (de) * | 1985-06-18 | 1990-04-26 | Schering Corp | Azanaphthalene enthaltende arzneimittelzusammensetzungen. |
US4801589A (en) * | 1986-06-12 | 1989-01-31 | Schering Corporation | Method for suppressing the immune response |
US5011860A (en) * | 1986-04-11 | 1991-04-30 | Schering Corporation | Aryl-substituted naphthyridine and pyridopyrazine derivatives and their use in treating hyperproliferative skin diseases |
US4760073A (en) * | 1986-04-11 | 1988-07-26 | Schering Corporation | Aryl-substituted naphthyridine and pyridopyrazine derivatives, useful as anti-allergic agents |
US4882332A (en) * | 1986-10-20 | 1989-11-21 | Schering Corporation | Immune suppression method employing arly-substituted naphthyridine and pyridopyrazine derivatives |
FI88033C (fi) * | 1986-04-11 | 1993-03-25 | Schering Corp | Foerfarande foer framstaellning av farmakologiskt vaerdefulla cyklobuta-, cyklopenta- och 7,8,9,10-tetrahydrobenso/c//1,8/naftyridin-6-onderivat |
US5037826A (en) * | 1986-10-15 | 1991-08-06 | Schering Corporation | 1-substituted naphthyridine and pyridopyrazine derivatives |
US5045542A (en) * | 1986-10-20 | 1991-09-03 | Schering Corporation | Immune suppression method employing aryl-substituted naphthyridine and pyridopyrazine derivatives |
US5350755A (en) * | 1986-12-05 | 1994-09-27 | Schering Corporation | Compounds and methods for treating hyperproliferative skin disease |
CA1309658C (fr) * | 1986-12-05 | 1992-11-03 | David J. Blythin | Compositions pharmaceutiques pour le traitement des maladies hyperproliferatives de la peau |
US4740511A (en) * | 1987-02-18 | 1988-04-26 | Schering Corporation | Method of treating hyperproliferative skin disease |
ZA875183B (en) * | 1987-07-15 | 1988-04-08 | Schering Corporation | Fused benzazepines |
US4897487A (en) * | 1988-04-06 | 1990-01-30 | Schering Corporation | Process for preparing intermediates for pharmaceutically useful bicyclic compounds |
US5202440A (en) * | 1987-10-05 | 1993-04-13 | Pfizer Inc. | Certain 9-amino-2-(or 4)-oxa 1,2,3,4-tetrahydro- or 1,2,3,4,5,6,7,8-octahydro-acridines |
WO1989002739A1 (fr) * | 1987-10-05 | 1989-04-06 | Pfizer Inc. | Derives de 4-aminopyridine |
US4859669A (en) * | 1987-12-23 | 1989-08-22 | Schering Corporation | Antiinflammatory and anti-hyperproliferative naphthyridin-4-ones |
US5180823A (en) * | 1988-04-06 | 1993-01-19 | Schering Corporation | Processes for preparing bicyclic compounds |
US5079360A (en) * | 1988-04-06 | 1992-01-07 | Schering Corporation | Processes for preparing bicyclic compounds and intermediates thereof |
US4996212A (en) * | 1989-12-21 | 1991-02-26 | Schering Corporation | Antiinflammatory and anti-hyperproliferative compounds |
US7138393B2 (en) | 1998-07-24 | 2006-11-21 | Wyeth | Biologically active vasopressin agonist metabolites |
EP2147679B1 (fr) | 2001-07-25 | 2014-06-25 | Raptor Pharmaceutical, Inc. | Compositions pour le transport de barrière hématoencéphalique |
DK1889198T3 (da) | 2005-04-28 | 2015-02-09 | Proteus Digital Health Inc | Farma-informatiksystem |
WO2008036682A2 (fr) | 2006-09-18 | 2008-03-27 | Raptor Pharmaceutical Inc. | Traitement des troubles hépatiques par l'administration de conjugués de protéine associée au récepteur (rap) |
EP2367821B1 (fr) * | 2008-12-17 | 2015-09-16 | Merck Patent GmbH | Inhibiteurs de protéines kinases de type benzonaphtyridinones tricycliques modifiées sur le noyau c et leur utilisation |
DK2398500T3 (da) | 2009-02-20 | 2019-05-13 | 2 Bbb Medicines B V | Glutathion-baseret lægemiddelafgivelsessystem |
IL255113B (en) | 2009-05-06 | 2022-09-01 | Laboratory Skin Care Inc | Preparations for administration through the skin that include complexes of an active substance with calcium phosphate and methods of using them |
US20120077778A1 (en) | 2010-09-29 | 2012-03-29 | Andrea Bourdelais | Ladder-Frame Polyether Conjugates |
CN113943288A (zh) * | 2020-07-17 | 2022-01-18 | 微境生物医药科技(上海)有限公司 | 5,6-二氢吡嗪并[2,3-c]异喹啉化合物 |
CN115611896A (zh) * | 2021-07-16 | 2023-01-17 | 中国药科大学 | 含四氢萘啶酮或四氢吡啶并嘧啶酮骨架的化合物及其制备方法与制药用途 |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB855022A (en) * | 1957-08-06 | 1960-11-30 | Geigy Ag J R | Improvements in and relating to carbostyril derivatives |
IT1054655B (it) * | 1975-08-27 | 1981-11-30 | Lepetit Spa | Derivati condensati del l isochinolina |
JPS5854152B2 (ja) * | 1976-03-25 | 1983-12-02 | 久光製薬株式会社 | 新規なナフチリジン誘導体 |
EP0005745B1 (fr) * | 1978-05-26 | 1982-07-14 | Gruppo Lepetit S.P.A. | Pyrazolo (3,4-c) et thiazolo (5,4-c) isoquinolines, procédé pour leur préparation, ces composés utilisables comme agent anti-inflammatoire anti-anxiété et à action sur le SNC, et compositions pharmaceutiques les contenant |
NL89090C (fr) * | 1978-06-05 | |||
US4452800A (en) * | 1982-04-26 | 1984-06-05 | Schering Corporation | Salts of 3(n-butyl)-4-hydroxy-1-phenyl-1,8-naphthyridine-2(1H)-one and their use in treating chronic obstructive lung diseases |
DE3368929D1 (de) * | 1982-04-26 | 1987-02-12 | Schering Corp | 1,8-naphthyridine and 1,5,8-azanaphthyridine derivatives |
-
1984
- 1984-04-09 US US06/597,887 patent/US4680298A/en not_active Expired - Lifetime
- 1984-05-24 EP EP84105923A patent/EP0127135B1/fr not_active Expired - Lifetime
- 1984-05-24 DE DE8484105923T patent/DE3483064D1/de not_active Expired - Fee Related
- 1984-05-29 IL IL71960A patent/IL71960A/xx unknown
- 1984-05-29 GR GR74858A patent/GR81552B/el unknown
- 1984-05-29 AU AU28824/84A patent/AU559754B2/en not_active Ceased
- 1984-05-29 GB GB08413582A patent/GB2142013B/en not_active Expired
- 1984-05-29 PH PH30728A patent/PH22970A/en unknown
- 1984-05-29 NZ NZ208310A patent/NZ208310A/en unknown
- 1984-05-29 DK DK264784A patent/DK160557C/da not_active IP Right Cessation
- 1984-05-30 JP JP59110656A patent/JPH0747590B2/ja not_active Expired - Lifetime
- 1984-05-30 CA CA000455491A patent/CA1251208A/fr not_active Expired
-
1990
- 1990-10-15 SG SG838/90A patent/SG83890G/en unknown
-
1992
- 1992-01-23 HK HK80/92A patent/HK8092A/xx unknown
Also Published As
Publication number | Publication date |
---|---|
GR81552B (fr) | 1984-12-11 |
CA1251208A (fr) | 1989-03-14 |
GB2142013A (en) | 1985-01-09 |
EP0127135A3 (en) | 1985-08-21 |
IL71960A0 (en) | 1984-09-30 |
HK8092A (en) | 1992-01-31 |
GB2142013B (en) | 1987-01-21 |
AU559754B2 (en) | 1987-03-19 |
NZ208310A (en) | 1986-11-12 |
SG83890G (en) | 1990-11-23 |
EP0127135A2 (fr) | 1984-12-05 |
IL71960A (en) | 1988-07-31 |
DK264784D0 (da) | 1984-05-29 |
JPS6034967A (ja) | 1985-02-22 |
JPH0747590B2 (ja) | 1995-05-24 |
DE3483064D1 (de) | 1990-10-04 |
PH22970A (en) | 1989-02-10 |
AU2882484A (en) | 1984-12-06 |
DK160557B (da) | 1991-03-25 |
EP0127135B1 (fr) | 1990-08-29 |
DK264784A (da) | 1984-12-01 |
US4680298A (en) | 1987-07-14 |
GB8413582D0 (en) | 1984-07-04 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DK160557C (da) | 1,8-naphthyridinforbindelser og farmaceutiske praeparater indeholdende saadanne | |
DK108388D0 (da) | Piperazinylalkylheterocycliske forbindelser og farmaceutiske praeparater indeholdende disse | |
DK163923C (da) | 2-phenyl-3-aminomethyl-imidazooe1,2-aaapyridinderivater og farmaceutisk praeparat indeholdende saadanne forbindelser | |
DK165112C (da) | 2,2'-iminobisethanolderivater, fremgangsmaade til fremstilling deraf og farmaceutisk praeparat indeholdende disse | |
DK165949C (da) | 1,4-dihydropyridinderivater, fremgangsmaader til fremstilling deraf og farmaceutiske praeparater indeholdende forbindelserne | |
DK475684D0 (da) | Phenothiazinderivater og farmaceutiske praeparater indeholdende phenothiazinderivaterne | |
DK287188D0 (da) | Cephalosporinforbindelser og farmaceutisk praeparat deraf | |
DK163990C (da) | Oxindol-3-carboxamid-derivater og farmaceutiske praeparater indeholdende disse | |
DK327983D0 (da) | Farmaceutiske praeparater og produkter | |
DK375584D0 (da) | Piperidinoquinazolinforbindelser og farmaceutisk praeparat indeholdene en saadan forbindelse | |
DK78888A (da) | Arylpiperazinylalkylenphenyl-heterocycliske forbindelser og farmaceutiske praeparater indeholdende disse | |
GB8306264D0 (en) | Pharmaceutical preparations | |
DK340388D0 (da) | Aminocyklopentylaetere, fremstilling deraf og farmaceutisk praeparat indeholdende saadanne forbindelser | |
DK269289D0 (da) | Cyklopentanderivater og farmaceutiske praeparater indeholdende saadanne forbindelser | |
DK21785D0 (da) | Dihydropyridinforbindelser og farmaceutiske praeparater indeholdende disse | |
DK158003C (da) | 1,3-dihydro-6-methyl-7-hydroxy-furo-(3,4-c)-pyridinderivat og farmaceutisk praeparat indeholdende en saadan forbindelse | |
DK81185D0 (da) | Carboxicam-enolester-forbindelser og farmaceutiske praeparater indeholdende disse | |
DK422984A (da) | Aminocyklopentaner og farmaceutiske praeparater deraf | |
DK508684A (da) | (1,3)oxazino(4,3-a)-isoquinolinderivater og farmaceutiske praeparater indeholdende saadanne | |
KR900700471A (ko) | 신규의 2,3-티오모르폴린디온-2-옥심유도체, 이들을 함유하는 약제학적 조성물 및 제법 | |
GB8304182D0 (en) | Pharmaceutical preparations | |
GB8328713D0 (en) | Pharmaceutical preparations | |
DK151785D0 (da) | 3-aminoalkylthio-1-phenylindolforbindelser og farmaceutiske praeparater | |
DK163826C (da) | 1,4-dihydro-3-carboxy-6,8-difluor-4-oxoquinolin-derivater, fremgangsmaade til fremstilling deraf og farmaceutiske praeparater indeholdende saadanne derivater | |
DK162089C (da) | 1-phenoxy-3-hydroxyindolylalkylamino-2-propanoler og farmaceutiske praeparater indeholdende disse |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PBP | Patent lapsed |