DK160548C - 4-hydroxymethyl-2-pyrrolidinoner til anvendelse som mellemprodukter ved fremstilling af 4-(4-disubstitueret piperidinylmethyl)-3,3-diphenyl-2-pyrrolidinoner - Google Patents

4-hydroxymethyl-2-pyrrolidinoner til anvendelse som mellemprodukter ved fremstilling af 4-(4-disubstitueret piperidinylmethyl)-3,3-diphenyl-2-pyrrolidinoner

Info

Publication number
DK160548C
DK160548C DK426376A DK426376A DK160548C DK 160548 C DK160548 C DK 160548C DK 426376 A DK426376 A DK 426376A DK 426376 A DK426376 A DK 426376A DK 160548 C DK160548 C DK 160548C
Authority
DK
Denmark
Prior art keywords
pyrrolidinones
piperidinylmethyl
disubstituted
hydroxymethyl
intermediates
Prior art date
Application number
DK426376A
Other languages
Danish (da)
English (en)
Other versions
DK426376A (da
DK160548B (da
Inventor
Jr Albert Duncan Cale
Original Assignee
Robins Co Inc A H
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Robins Co Inc A H filed Critical Robins Co Inc A H
Publication of DK426376A publication Critical patent/DK426376A/da
Publication of DK160548B publication Critical patent/DK160548B/da
Application granted granted Critical
Publication of DK160548C publication Critical patent/DK160548C/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24Oxygen or sulfur atoms
    • C07D207/262-Pyrrolidones
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D205/00Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/04Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/26Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D307/30Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/32Oxygen atoms
    • C07D307/33Oxygen atoms in position 2, the oxygen atom being in its keto or unsubstituted enol form

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pyrrole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Furan Compounds (AREA)
DK426376A 1975-09-23 1976-09-22 4-hydroxymethyl-2-pyrrolidinoner til anvendelse som mellemprodukter ved fremstilling af 4-(4-disubstitueret piperidinylmethyl)-3,3-diphenyl-2-pyrrolidinoner DK160548C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US61595175 1975-09-23
US05/615,951 US4119637A (en) 1975-09-23 1975-09-23 4-Hydroxymethyl-2-pyrrolidinones

Publications (3)

Publication Number Publication Date
DK426376A DK426376A (da) 1977-03-24
DK160548B DK160548B (da) 1991-03-25
DK160548C true DK160548C (da) 1991-09-09

Family

ID=24467444

Family Applications (1)

Application Number Title Priority Date Filing Date
DK426376A DK160548C (da) 1975-09-23 1976-09-22 4-hydroxymethyl-2-pyrrolidinoner til anvendelse som mellemprodukter ved fremstilling af 4-(4-disubstitueret piperidinylmethyl)-3,3-diphenyl-2-pyrrolidinoner

Country Status (21)

Country Link
US (1) US4119637A (ja)
JP (2) JPS6059228B2 (ja)
AU (2) AU512445B2 (ja)
BE (1) BE846402A (ja)
BR (1) BR7606209A (ja)
CA (1) CA1077497A (ja)
CH (1) CH616659A5 (ja)
DE (2) DE2642608A1 (ja)
DK (1) DK160548C (ja)
ES (2) ES451752A1 (ja)
FI (1) FI67370C (ja)
FR (2) FR2333792A1 (ja)
GB (2) GB1552686A (ja)
IE (1) IE44843B1 (ja)
IL (1) IL50436A (ja)
MX (1) MX3846E (ja)
NL (1) NL7610526A (ja)
PH (1) PH13940A (ja)
PT (1) PT65624B (ja)
SE (1) SE418397B (ja)
ZA (1) ZA765417B (ja)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4133881A (en) * 1977-04-27 1979-01-09 A. H. Robins Company, Incorporated Azetidinyl acetonitrile and acetamide antiarrhythmia compositions and methods
DE3326724A1 (de) * 1983-07-25 1985-02-07 Boehringer Ingelheim KG, 6507 Ingelheim In 1-stellung substituierte 4-hydroxymethyl-pyrrolidinone, verfahren zu ihrer herstellung, pharmazeutische zusammensetzungen und zwischenprodukte
GB8419085D0 (en) * 1984-07-26 1984-08-30 Shell Int Research Azetidine derivatives
DE3537075A1 (de) * 1985-10-18 1987-04-23 Bayer Ag Verfahren zur herstellung von clausenamid
DE3823299A1 (de) * 1988-07-07 1990-01-11 Schering Ag Substituierte phenyl-pyrrolidin-2-one, -oxazolidin-2-one und -imidazolidin-2-one, ihre herstellung sowie verwendung in arzneimitteln

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2650231A (en) * 1949-11-19 1953-08-25 Smith Kline French Lab Aminovalerolactones and method for their production
JPS5422973B2 (ja) * 1972-03-17 1979-08-10
FR2235685A1 (en) * 1973-06-20 1975-01-31 Ugine Kuhlmann 1-Amino alkyl-3,3-diphenyl-2-pyrrolidinones - useful as coronary dilators, anti histamines choleretics etc.
ES442233A1 (es) * 1974-11-06 1977-07-01 Hoechst Ag Procedimiento para la preparacion de pirrolidonas.

Also Published As

Publication number Publication date
SE7610362L (sv) 1977-03-24
ES451752A1 (es) 1978-01-01
FR2333792A1 (fr) 1977-07-01
JPS5248662A (en) 1977-04-18
PH13940A (en) 1980-11-04
MX3846E (es) 1981-08-18
FR2329665B1 (ja) 1981-07-10
AU1804876A (en) 1978-04-06
DK426376A (da) 1977-03-24
DE2642608A1 (de) 1977-03-31
DE2642608C2 (ja) 1987-03-19
JPS6127977A (ja) 1986-02-07
JPS6059228B2 (ja) 1985-12-24
GB1552686A (en) 1979-09-19
CH616659A5 (ja) 1980-04-15
BR7606209A (pt) 1977-06-14
PT65624A (en) 1976-10-01
BE846402A (fr) 1977-01-17
AU512445B2 (en) 1980-10-09
IE44843L (en) 1977-03-23
ES458181A1 (es) 1978-04-01
FR2329665A1 (fr) 1977-05-27
GB1552687A (en) 1979-09-19
CA1077497A (en) 1980-05-13
FR2333792B1 (ja) 1981-08-21
IE44843B1 (en) 1982-04-21
JPS6154793B2 (ja) 1986-11-25
SE418397B (sv) 1981-05-25
US4119637A (en) 1978-10-10
IL50436A (en) 1980-01-31
FI67370B (fi) 1984-11-30
DE2661028C2 (ja) 1987-08-06
NL7610526A (nl) 1977-03-25
IL50436A0 (en) 1976-11-30
FI67370C (fi) 1985-03-11
ZA765417B (en) 1977-08-31
DK160548B (da) 1991-03-25
PT65624B (en) 1978-04-05
FI762694A (ja) 1977-03-24

Similar Documents

Publication Publication Date Title
DK157080C (da) 7beta-amino-3-cephem-3-amino-4-carboxylsyrederivater til anvendelse som mellemprodukter ved fremstilling af 7beta-amino-3-cephem-3-ol-4-carboxylsyreforbindelser
NO146907C (no) N,n`-acylamido-trijord-benzoylerte alkylen-diaminforbindelser for anvendelse som roentgenkontrastmidler
DK157293C (da) Propionitril til anvendelse som mellemprodukt ved fremstilling af 6-aminosubstituerede-5-r3-2,4-diaminopyrimidin-3-oxider
DK160548C (da) 4-hydroxymethyl-2-pyrrolidinoner til anvendelse som mellemprodukter ved fremstilling af 4-(4-disubstitueret piperidinylmethyl)-3,3-diphenyl-2-pyrrolidinoner
DK63990D0 (da) 7-aminocephalosporinderivater til anvendelse som mellemprodukt til fremstilling af sephalosporinderivater
DK152120C (da) Analogifremgangsmaade til fremstilling af 4-(2-acyloxy-3-tert.butylaminopropoxy)-indolderivater
DK155329C (da) 7-aminocephalosporiner til anvendelse som mellemprodukter ved fremstilling af terapeutisk virksomme 7-acylamino-cephalosporiner
ES482438A0 (es) Procedimiento para la preparacion de nuevos derivados de 2-(4-aminopiperidino)-3,4-dihidroquinoleina.
DK139389B (da) Salte af benzylpenicillin til anvendelse som mellemprodukter ved fremstillingen af estere af benzylpenicillin.
SE413092B (sv) 5,6-dialkoxi - 3,4-dihydro - 2(1h)-naftalenoner till anvendning som mellanprodukter for framstellning av vissa emetiska 2-aminotetraloner
DK29276A (da) Fremgangsmade til fremstilling af 8-bromothieno-triazolo-1,4-diazepiner
DK126077A (da) Fremgangsmade til fremstilling af 2,6-di-tert-butylphenol
DK162094C (da) 2-(2-tritylamino-4-thiazolyl)-2-vinyloxyiminoeddikesyre, syn-isomer, til anvendelse som mellemprodukt ved fremstilling af syn-isomere oximderivater af 7-aminothiazolylacetamidocephalosporansyre samt fremgangsmaade til fremstilling af mellemproduktet
DK142575C (da) 4-hydroxyindazolderivater til anvendelse som mellemprodukter til fremstilling af indazolyl-(4)-oxy-propanolaminderivater med beta-receptorblokerende virkning
DK144698C (da) 2,4-diamino-6-halogen-5-benzylpyrimidiner til anvendelse som mellemprodukter ved fremstilling af 2,4-diamino-5-benzylpyrimidiner
DK157681C (da) Phenyl-oe2-(5-hydroxymethyl-1-imidazolyl)-phenylaa-methanonderivater til anvendelse som mellemprodukter ved fremstillingen af imidazooe1,5-aaaoe1,4aabenzodiazepinderivater
DK146179C (da) 1,5-disubstituerede 3ae-oxo-2-pyrrolidon-forbindelser til anvendelse som mellemprodukter ved fremstilling af 1,5-disubstituerede 2-pyrrolidon-forbindelser
DK374484D0 (da) 1,4-dihydropyridinderivater til anvendelse som mellemprodukter ved frmstilling af farmaceutisk aktive 1,4-dihydropyridinderivater
DK160987C (da) 9,10-dihydroxy-perhydroisoquinolinderivater til anvendelse som mellemprodukt ved fremstilling af 14-hydroxy-morphinanderivater
DK155660C (da) 1-aryloxy-4-chlor-2-butanoler til anvendelse som mellemprodukter ved fremstilling af 1-aryloxy-4-amino-2-butanoler
DK143134C (da) 6-halogen-3-oxo-2-oxabicyklo(3,2,1)octan-8-carbaldehydforbindelser til anvendelse som mellemprodukter ved fremstilling af prostaglandiner og prostaglandinlignende forbindelser
DK140722B (da) Analogifremgangsmåde til fremstilling af aminoethyloximetherforbindelser med antidepressiv virkning.
DK145464C (da) 8-oxamorphinanderivater til anvendelse som mellemprodukter ved fremstilling af n-substituerede 3-hydroxy-8-oxamorphinaner
DK146802C (da) 2-hydroxymethyl-3-hydroxypyridin-6-epoxyethanderivater til anvendelse som mellemprodukter ved fremstilling af 2-hydroxymethyl-3-hydroxy-6-(1-hydroxy-2-t-butylaminoethyl)pyridin
DK146510C (da) 2-(4-(2-furoyl)piperazin-1-yl)-4-phthalimido-6,7-dimethoxyquinazolin til anvendelse som mellemprodukt ved fremstilling af 2-(4-(2-furoyl)piperazin-1-yl)-4-amino-6,7-dimethoxyquinazolin

Legal Events

Date Code Title Description
PBP Patent lapsed