DK159188D0 - Ekspressionsvektor, der er i stand til at styre ekspression af heterologe gener eller cdna i gaer, gaervaertscelle samt fremgangsmaade til oeget produktion af proteiner i gaervaertsceller - Google Patents
Ekspressionsvektor, der er i stand til at styre ekspression af heterologe gener eller cdna i gaer, gaervaertscelle samt fremgangsmaade til oeget produktion af proteiner i gaervaertscellerInfo
- Publication number
- DK159188D0 DK159188D0 DK159188A DK159188A DK159188D0 DK 159188 D0 DK159188 D0 DK 159188D0 DK 159188 A DK159188 A DK 159188A DK 159188 A DK159188 A DK 159188A DK 159188 D0 DK159188 D0 DK 159188D0
- Authority
- DK
- Denmark
- Prior art keywords
- cells
- cdna
- expression vector
- expression
- gerte
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/1025—Acyltransferases (2.3)
- C12N9/104—Aminoacyltransferases (2.3.2)
- C12N9/1044—Protein-glutamine gamma-glutamyltransferase (2.3.2.13), i.e. transglutaminase or factor XIII
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4721—Lipocortins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/81—Protease inhibitors
- C07K14/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
- C07K14/811—Serine protease (E.C. 3.4.21) inhibitors
- C07K14/8121—Serpins
- C07K14/8125—Alpha-1-antitrypsin
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/67—General methods for enhancing the expression
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
- C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US2986787A | 1987-03-23 | 1987-03-23 | |
US2986787 | 1987-03-23 |
Publications (3)
Publication Number | Publication Date |
---|---|
DK159188D0 true DK159188D0 (da) | 1988-03-23 |
DK159188A DK159188A (da) | 1988-12-14 |
DK175243B1 DK175243B1 (da) | 2004-07-19 |
Family
ID=21851327
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK198801591A DK175243B1 (da) | 1987-03-23 | 1988-03-23 | Ekspressionsvektor, der er i stand til at styre ekspression af heterologe gener eller cDNA i gær, gærværtscelle samt fremgangsmåde til öget produktion af proteiner i gærværtsceller |
Country Status (6)
Country | Link |
---|---|
EP (1) | EP0284044B1 (da) |
JP (1) | JP2795850B2 (da) |
AT (1) | ATE103333T1 (da) |
CA (1) | CA1304020C (da) |
DE (1) | DE3888561T2 (da) |
DK (1) | DK175243B1 (da) |
Families Citing this family (65)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3906540A1 (de) * | 1989-03-02 | 1990-09-13 | Behringwerke Ag | Expressionsvektoren zur synthese von proteinen in der spalthefe schizosaccharomyces pombe |
US5225537A (en) * | 1989-12-29 | 1993-07-06 | Zymogenetics, Inc. | Methods for producing hybrid phospholipid-binding proteins |
FR2656531B1 (fr) * | 1989-12-29 | 1992-04-24 | Sanofi Sa | Promoteur artificiel pour l'expression de proteines dans le levure. |
WO1992009698A1 (en) | 1990-11-26 | 1992-06-11 | Genetics Institute, Inc. | Expression of pace in host cells and methods of use thereof |
US5407822A (en) * | 1991-10-02 | 1995-04-18 | Sanofi | Artificial promoter for the expression of proteins in yeast |
FI924494A0 (fi) * | 1992-10-06 | 1992-10-06 | Valtion Teknillinen | Oekad produktion av avsoendrarde proteiner i eukaryotiska rekombinantceller |
US5817478A (en) * | 1993-10-05 | 1998-10-06 | Asahi Glass Company Ltd. | Multicloning vector, expression vector and production of foreign proteins by using the expression vector |
US5629167A (en) * | 1994-04-19 | 1997-05-13 | Biocine S.P.A. | Detection of antibodies against Chlamydia trachomatis pgp3 antigen in patient sera by enzyme-linked immunosorbent assay |
US6024816A (en) | 1995-01-27 | 2000-02-15 | The Yokohama Rubber Co., Ltd. | Pneumatic tire and process for production thereof |
GB2318732A (en) | 1996-11-01 | 1998-05-06 | Johnson & Johnson Medical | Wound healing compositions containing alpha-1-antitrypsin |
FI972909A0 (fi) | 1997-07-09 | 1997-07-09 | Valtion Teknillinen | Oekad produktion av avsoendrade proteiner genom rekombinatjaestceller |
DE19736343B4 (de) | 1997-08-21 | 2006-02-09 | Forschungszentrum Jülich GmbH | Verfahren zur Erhöhung der Genexpression von Saccharose Synthase |
AU748759B2 (en) * | 1997-09-05 | 2002-06-13 | Pentapharm Ag | Expression vector for improved production of polypeptides in yeast |
FR2768743B1 (fr) | 1997-09-23 | 2001-09-14 | Bio Merieux | Procede de lyse de micro-organisme |
CN1263854C (zh) | 1997-11-06 | 2006-07-12 | 启龙股份公司 | 奈瑟球菌抗原 |
DK1047784T4 (da) | 1998-01-14 | 2015-06-15 | Novartis Vaccines & Diagnostic | Neissera meningitidis-antigener |
GB9808932D0 (en) | 1998-04-27 | 1998-06-24 | Chiron Spa | Polyepitope carrier protein |
PT1645631E (pt) | 1998-05-01 | 2008-02-04 | Novartis Vaccines & Diagnostic | Anitigénios da neisseria meningitidis e composições |
US6358705B1 (en) | 1998-07-16 | 2002-03-19 | Novo Nordisk A/S | Method of making proteins in transformed yeast cells |
FR2781500B1 (fr) * | 1998-07-23 | 2000-09-08 | Bio Merieux | Dispositif perfectionne et procede de lyse de micro-organismes |
NZ581940A (en) | 1999-04-30 | 2011-07-29 | Novartis Vaccines & Diagnostic | Conserved neisserial antigens |
GB9911683D0 (en) | 1999-05-19 | 1999-07-21 | Chiron Spa | Antigenic peptides |
GB9916529D0 (en) | 1999-07-14 | 1999-09-15 | Chiron Spa | Antigenic peptides |
CA2864069A1 (en) | 1999-10-29 | 2001-05-03 | Novartis Vaccines And Diagnostics S.R.L. | Neisserial antigenic peptides |
US6709863B2 (en) | 1999-12-08 | 2004-03-23 | Iowa State University Research Foundation | Nucleic acid molecules encoding multiple start codons and histidine tags |
EP2281571A3 (en) | 2000-01-17 | 2012-04-25 | Novartis Vaccines and Diagnostics S.r.l. | Outer membrane vesicle (omv) vaccine comprising n. meningitidids serogroup b outer membrane proteins |
EP2284183A1 (en) | 2000-10-27 | 2011-02-16 | Novartis Vaccines and Diagnostics S.r.l. | Nucleic acids and proteins from streptococcus groups A and B |
GB0107661D0 (en) | 2001-03-27 | 2001-05-16 | Chiron Spa | Staphylococcus aureus |
GB0107658D0 (en) | 2001-03-27 | 2001-05-16 | Chiron Spa | Streptococcus pneumoniae |
CN101724075B (zh) | 2001-10-10 | 2014-04-30 | 诺和诺德公司 | 肽的重构和糖缀合 |
EP2298354B1 (en) | 2001-10-10 | 2014-03-19 | ratiopharm GmbH | Remodelling and glycoconjugation of interferon-beta |
EP2335724A1 (en) | 2001-12-12 | 2011-06-22 | Novartis Vaccines and Diagnostics S.r.l. | Immunisation against chlamydia trachomatis |
AU2003243316A1 (en) | 2002-05-24 | 2003-12-12 | Nps Allelix Corp. | Method for enzymatic production of glp-2(1-33) and glp-2-(1-34) peptides |
EP1562982B1 (en) | 2002-11-15 | 2010-05-05 | Novartis Vaccines and Diagnostics S.r.l. | Unexpected surface proteins in neisseria meningitidis |
US20070026485A1 (en) | 2003-04-09 | 2007-02-01 | Neose Technologies, Inc. | Glycopegylation methods and proteins/peptides produced by the methods |
GB0308198D0 (en) | 2003-04-09 | 2003-05-14 | Chiron Srl | ADP-ribosylating bacterial toxin |
WO2005014825A2 (en) * | 2003-08-08 | 2005-02-17 | Arriva Pharmaceuticals, Inc. | Methods of protein production in yeast |
US7829307B2 (en) | 2003-11-21 | 2010-11-09 | Nps Pharmaceuticals, Inc. | Production of glucagon-like peptide 2 |
NZ586034A (en) | 2004-02-02 | 2011-10-28 | Ambrx Inc | Modified human growth hormone polypeptides and their uses |
US20060021087A1 (en) | 2004-04-09 | 2006-01-26 | Baum James A | Compositions and methods for control of insect infestations in plants |
US7632924B2 (en) | 2004-06-18 | 2009-12-15 | Ambrx, Inc. | Antigen-binding polypeptides and their uses |
US7736872B2 (en) | 2004-12-22 | 2010-06-15 | Ambrx, Inc. | Compositions of aminoacyl-TRNA synthetase and uses thereof |
WO2006069246A2 (en) | 2004-12-22 | 2006-06-29 | Ambrx, Inc. | Compositions containing, methods involving, and uses of non-natural amino acids and polypeptides |
CA2594557C (en) | 2004-12-22 | 2016-04-26 | Ambrx, Inc. | Modified human growth hormone |
JP4829969B2 (ja) | 2005-08-18 | 2011-12-07 | アンブルックス,インコーポレイテッド | tRNA組成物、およびその使用 |
PL2431473T3 (pl) | 2005-09-16 | 2017-05-31 | Monsanto Technology Llc | Sposoby genetycznej kontroli inwazji owadów u roślin i kompozycje do tego przeznaczone |
CA2622671C (en) | 2005-09-16 | 2020-12-22 | Devgen Nv | Methods for controlling pests using rnai |
CN101454461A (zh) | 2005-11-16 | 2009-06-10 | Ambrx公司 | 包括非天然氨基酸的方法和组合物 |
JP2009519942A (ja) | 2005-12-14 | 2009-05-21 | アンブルックス,インコーポレイテッド | 非天然アミノ酸およびポリペプチドを含んでいる組成物、それらに関する方法、ならびに、それらの使用 |
CA2836368C (en) | 2006-02-13 | 2020-04-07 | Monsanto Technology Llc | Method for managing crop pest resistance |
EP2035035A2 (en) | 2006-06-09 | 2009-03-18 | Novartis AG | Immunogenic compositions for streptococcus agalactiae |
JP5840345B2 (ja) | 2006-09-08 | 2016-01-06 | アンブルックス, インコーポレイテッドAmbrx, Inc. | 修飾ヒト血漿ポリペプチドまたは修飾ヒトFc足場タンパク質ならびにこれらの利用 |
KR101476472B1 (ko) | 2007-03-30 | 2015-01-05 | 암브룩스, 인코포레이티드 | 변형된 fgf-21 폴리펩티드 및 그 용도 |
AU2008326324B9 (en) | 2007-11-20 | 2012-11-15 | Ambrx, Inc. | Modified insulin polypeptides and their uses |
US9938333B2 (en) | 2008-02-08 | 2018-04-10 | Ambrx, Inc. | Modified leptin polypeptides and their uses |
ES2963062T3 (es) | 2008-07-23 | 2024-03-25 | Ambrx Inc | Polipéptidos G-CSF bovinos modificados y sus usos |
BRPI0919403A2 (pt) | 2008-09-26 | 2017-09-26 | Ambrx Inc | polipeptídeos modificados de eritropoetina animal e seus usos |
NZ592249A (en) | 2008-09-26 | 2013-03-28 | Ambrx Inc | Non-natural amino acid replication-dependent microorganisms and vaccines |
CN104017063A (zh) | 2009-12-21 | 2014-09-03 | Ambrx公司 | 经过修饰的猪促生长素多肽和其用途 |
CN107674121A (zh) | 2009-12-21 | 2018-02-09 | Ambrx 公司 | 经过修饰的牛促生长素多肽和其用途 |
EP2605789B1 (en) | 2010-08-17 | 2019-06-05 | Ambrx, Inc. | Modified relaxin polypeptides and their uses |
US9567386B2 (en) | 2010-08-17 | 2017-02-14 | Ambrx, Inc. | Therapeutic uses of modified relaxin polypeptides |
AR083006A1 (es) | 2010-09-23 | 2013-01-23 | Lilly Co Eli | Formulaciones para el factor estimulante de colonias de granulocitos (g-csf) bovino y variantes de las mismas |
KR20240024362A (ko) | 2014-10-24 | 2024-02-23 | 브리스톨-마이어스 스큅 컴퍼니 | 변형된 fgf-21 폴리펩티드 및 그의 용도 |
MX2019008449A (es) | 2017-02-08 | 2019-09-09 | Bristol Myers Squibb Co | Polipetidos de relaxina modificada que comprenden un mejorador farmacocinetico y sus usos. |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU600885B2 (en) * | 1984-05-25 | 1990-08-30 | Zymogenetics Inc. | Stable DNA constructs |
EP0245479B1 (en) * | 1985-11-13 | 1993-02-17 | Xoma Corporation | Shortened phosphoglycerate kinase promoter |
-
1988
- 1988-03-23 DK DK198801591A patent/DK175243B1/da not_active IP Right Cessation
- 1988-03-23 CA CA000562260A patent/CA1304020C/en not_active Expired - Lifetime
- 1988-03-23 DE DE3888561T patent/DE3888561T2/de not_active Expired - Lifetime
- 1988-03-23 EP EP88104649A patent/EP0284044B1/en not_active Expired - Lifetime
- 1988-03-23 AT AT88104649T patent/ATE103333T1/de not_active IP Right Cessation
- 1988-03-23 JP JP63069222A patent/JP2795850B2/ja not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
DK159188A (da) | 1988-12-14 |
JPS6416587A (en) | 1989-01-20 |
CA1304020C (en) | 1992-06-23 |
DE3888561D1 (de) | 1994-04-28 |
EP0284044B1 (en) | 1994-03-23 |
EP0284044A1 (en) | 1988-09-28 |
DK175243B1 (da) | 2004-07-19 |
JP2795850B2 (ja) | 1998-09-10 |
ATE103333T1 (de) | 1994-04-15 |
DE3888561T2 (de) | 1994-09-01 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PBP | Patent lapsed | ||
PUP | Patent expired |