DK157852C - Analogifremgangsmaade til fremstilling af prostacyclinderivater - Google Patents

Analogifremgangsmaade til fremstilling af prostacyclinderivater

Info

Publication number
DK157852C
DK157852C DK078181A DK78181A DK157852C DK 157852 C DK157852 C DK 157852C DK 078181 A DK078181 A DK 078181A DK 78181 A DK78181 A DK 78181A DK 157852 C DK157852 C DK 157852C
Authority
DK
Denmark
Prior art keywords
preparation
analogy procedure
treatment
methods
pgi2
Prior art date
Application number
DK078181A
Other languages
English (en)
Other versions
DK78181A (da
DK157852B (da
Inventor
Gerhard Beck
Jochen Knolle
Richard Helmut Rupp
Bernward Schoelkens
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of DK78181A publication Critical patent/DK78181A/da
Publication of DK157852B publication Critical patent/DK157852B/da
Application granted granted Critical
Publication of DK157852C publication Critical patent/DK157852C/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
    • C07D307/935—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/52—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring condensed with a ring other than six-membered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D309/10—Oxygen atoms
    • C07D309/12—Oxygen atoms only hydrogen atoms and one oxygen atom directly attached to ring carbon atoms, e.g. tetrahydropyranyl ethers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Indole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK078181A 1980-02-23 1981-02-20 Analogifremgangsmaade til fremstilling af prostacyclinderivater DK157852C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19803006865 DE3006865A1 (de) 1980-02-23 1980-02-23 Hetero-imino-prostacycline
DE3006865 1980-02-23

Publications (3)

Publication Number Publication Date
DK78181A DK78181A (da) 1981-08-24
DK157852B DK157852B (da) 1990-02-26
DK157852C true DK157852C (da) 1990-07-30

Family

ID=6095414

Family Applications (1)

Application Number Title Priority Date Filing Date
DK078181A DK157852C (da) 1980-02-23 1981-02-20 Analogifremgangsmaade til fremstilling af prostacyclinderivater

Country Status (17)

Country Link
US (1) US4371542A (da)
EP (1) EP0034778B1 (da)
JP (1) JPS56133265A (da)
AT (1) ATE7225T1 (da)
AU (1) AU545358B2 (da)
CA (1) CA1198106A (da)
DE (2) DE3006865A1 (da)
DK (1) DK157852C (da)
ES (2) ES8206473A1 (da)
FI (1) FI810509L (da)
HU (1) HU187318B (da)
IE (1) IE50957B1 (da)
IL (1) IL62197A (da)
MX (1) MX6834E (da)
NZ (1) NZ196316A (da)
PH (1) PH21973A (da)
ZA (1) ZA811146B (da)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2946756A1 (de) * 1979-11-20 1981-05-27 Hoechst Ag, 6000 Frankfurt Stickstoff-haltige prostaglandin/prostacyclin-synthone und verfahren zu ihrer herstellung
DE3100083A1 (de) * 1981-01-03 1982-08-05 Hoechst Ag, 6000 Frankfurt "11-desoxy-hetero-imino-prostacycline, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel"
DE3272423D1 (en) * 1981-04-13 1986-09-11 Schering Ag Prostaglandins and prostacyclins, their preparations and pharmaceutical applications
DE3117979A1 (de) * 1981-05-07 1983-01-20 Hoechst Ag, 6000 Frankfurt Neue(delta)1-pyrrolin-thiolactimaether und verfahren zu ihrer herstellung
JPS6028943A (ja) * 1983-07-26 1985-02-14 Sankyo Co Ltd カルバサイクリン類縁体
JPS60181041A (ja) * 1984-02-29 1985-09-14 Sankyo Co Ltd カルバサイクリン誘導体
US5221689A (en) * 1984-07-23 1993-06-22 Ono Pharmaceutical Co., Ltd. Prostaglandin analogues, processes for their preparation and pharmaceutical compositions containing them
JPS6130554A (ja) * 1984-07-23 1986-02-12 Ono Pharmaceut Co Ltd プロスタグランジン類似化合物のある特定の立体配置を有する異性体及びそれらを有効成分として含有する治療剤
CA1284642C (en) * 1986-03-31 1991-06-04 Hikozo Iwakura Prostacyclin (pgi ) analogues
EP0347243B1 (en) * 1988-06-17 1993-01-13 The Wellcome Foundation Limited Prostaglandin analogues for use in medicine
EP2484655A1 (en) * 2011-02-04 2012-08-08 Vironova AB A thionation process and a thionating agent

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4097489A (en) * 1977-06-17 1978-06-27 The Upjohn Company 9-Deoxy-9α,6-nitrilo or 6,9α-imino-PGF compounds
JPS54125653A (en) * 1978-03-18 1979-09-29 Ono Pharmaceut Co Ltd Prostaglandin i2 analog, its preparation, and drug composition comprising it as active constituent

Also Published As

Publication number Publication date
ES509176A0 (es) 1982-11-16
DK78181A (da) 1981-08-24
IE810349L (en) 1981-08-23
FI810509L (fi) 1981-08-24
US4371542A (en) 1983-02-01
DE3163263D1 (en) 1984-05-30
IE50957B1 (en) 1986-08-20
HU187318B (en) 1985-12-28
EP0034778A1 (de) 1981-09-02
JPH032860B2 (da) 1991-01-17
NZ196316A (en) 1984-08-24
IL62197A0 (en) 1981-03-31
AU6750981A (en) 1981-09-03
AU545358B2 (en) 1985-07-11
CA1198106A (en) 1985-12-17
EP0034778B1 (de) 1984-04-25
ES499484A0 (es) 1982-08-16
JPS56133265A (en) 1981-10-19
MX6834E (es) 1986-08-15
DE3006865A1 (de) 1981-09-10
ATE7225T1 (de) 1984-05-15
ES8206473A1 (es) 1982-08-16
PH21973A (en) 1988-05-02
IL62197A (en) 1986-09-30
ZA811146B (en) 1982-03-31
ES8301212A1 (es) 1982-11-16
DK157852B (da) 1990-02-26

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Legal Events

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PBP Patent lapsed