DK157549C - Analogifremgangsmaade til fremstilling af 6-(5-(omega-(1-imidazolyl)-alkyl)-thien-2-yl)-3-oxo-2,3,4,5-tetrahydropyridaziner eller syreadditionssalte deraf - Google Patents
Analogifremgangsmaade til fremstilling af 6-(5-(omega-(1-imidazolyl)-alkyl)-thien-2-yl)-3-oxo-2,3,4,5-tetrahydropyridaziner eller syreadditionssalte derafInfo
- Publication number
- DK157549C DK157549C DK343482A DK343482A DK157549C DK 157549 C DK157549 C DK 157549C DK 343482 A DK343482 A DK 343482A DK 343482 A DK343482 A DK 343482A DK 157549 C DK157549 C DK 157549C
- Authority
- DK
- Denmark
- Prior art keywords
- thien
- omega
- imidazolyl
- oxo
- alkyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE3130252 | 1981-07-31 | ||
DE19813130252 DE3130252A1 (de) | 1981-07-31 | 1981-07-31 | 6-(5-((omega)-(1-imidazolyl)-alkyl)-thien-2-yl)-3-oxo-2,3,4,5-tetrahydro-pyridazine und deren saeureadditionssalze, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate |
Publications (3)
Publication Number | Publication Date |
---|---|
DK343482A DK343482A (da) | 1983-02-01 |
DK157549B DK157549B (da) | 1990-01-22 |
DK157549C true DK157549C (da) | 1990-06-11 |
Family
ID=6138200
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK343482A DK157549C (da) | 1981-07-31 | 1982-07-30 | Analogifremgangsmaade til fremstilling af 6-(5-(omega-(1-imidazolyl)-alkyl)-thien-2-yl)-3-oxo-2,3,4,5-tetrahydropyridaziner eller syreadditionssalte deraf |
Country Status (9)
Country | Link |
---|---|
US (1) | US4504479A (da) |
EP (1) | EP0071059B1 (da) |
JP (1) | JPS5826885A (da) |
AT (1) | ATE22445T1 (da) |
DE (1) | DE3130252A1 (da) |
DK (1) | DK157549C (da) |
GR (1) | GR76191B (da) |
IE (1) | IE53469B1 (da) |
ZA (1) | ZA824882B (da) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3212304A1 (de) * | 1982-04-02 | 1983-10-06 | Nattermann A & Cie | Imidazolylphenyl-tetrahydropyridazine, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate |
DE3241102A1 (de) * | 1982-11-06 | 1984-05-10 | A. Nattermann & Cie GmbH, 5000 Köln | Imidazolylalkylthienyl-tetrahydropyridazine und verfahren zu ihrer herstellung |
DE3310197A1 (de) * | 1983-03-21 | 1984-09-27 | A. Nattermann & Cie GmbH, 5000 Köln | Substituierte 3-mercapto-pyridazine und deren 3-alkylthioderivate sowie verfahren zu ihrer herstellung |
DE3321012A1 (de) * | 1983-06-10 | 1984-12-13 | A. Nattermann & Cie GmbH, 5000 Köln | Substituierte 4,5-dihydro-6-(thien-2-yl)-3(2h)-pyridazinone und 6-(thien-2-yl)-3(2h)-pyridazinone sowie verfahren zu ihrer herstellung |
US4599332A (en) * | 1983-12-07 | 1986-07-08 | Warner-Lambert Company | 4,5-dihydro-6-[2-[4-(1H-imidazol-1-yl)phenyl]-ethenyl]-3(2H)-pyridazinones and related compounds |
DE3401911A1 (de) * | 1984-01-20 | 1985-08-01 | A. Nattermann & Cie GmbH, 5000 Köln | Substituierte 4,5-dihydro-6-vinyl-3(2h)-pyridazinone und 6-vinyl-3(2h)-pyridazinone sowie verfahren zu ihrer herstellung |
US4826835A (en) * | 1985-10-23 | 1989-05-02 | Rorer Pharmaceutical Corporation | Pyridyl-pyridazinone and pyridyl-pyrazolinone compounds and their use in the treatment of congestive heart failure |
US4783463A (en) * | 1985-10-23 | 1988-11-08 | Rorer Pharmaceutical Corporation | Pyridyl-pyridazinone and pyridyl-pyrazolinone compounds and their use in the treatment of congestive heart failure |
US4970210A (en) * | 1987-07-17 | 1990-11-13 | Abbott Laboratories | Triazinone lipoxygenase compounds |
US20180104220A1 (en) * | 2015-04-24 | 2018-04-19 | Medshine Discovery Inc. | Imidazole compound |
WO2018072702A1 (zh) * | 2016-10-20 | 2018-04-26 | 南京明德新药研发股份有限公司 | 一种咪唑类化合物的晶型、盐型及其制备方法 |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1383906A (en) * | 1971-02-22 | 1974-02-12 | Bdh Pharmaceuticals Ltd | Pyridazinones |
BE790106A (fr) * | 1971-10-14 | 1973-04-13 | Basf Ag | Dihydropyridazones, leur preparation et leurs utilisations therapeutiques |
US4057634A (en) * | 1974-01-24 | 1977-11-08 | Hoechst Aktiengesellschaft | Antiprotozoal(1-alkyl-5-nitro-imidazolyl-2-alkyl)-pyridazines |
JPS5951943B2 (ja) * | 1978-08-21 | 1984-12-17 | キツセイ薬品工業株式会社 | 新規なイミダゾ−ル誘導体 |
DE3005287A1 (de) * | 1980-02-13 | 1981-08-20 | Basf Ag, 6700 Ludwigshafen | Phenylpiperazinderivate von 1,3,4-oxadiazolylphenolen, ihre herstellung und diese enthaltende therapeutische mittel |
US4353905A (en) * | 1981-09-17 | 1982-10-12 | Warner-Lambert Company | Substituted 4,5-dihydro-6-[4-(1H-imidazol-1-yl)phenyl]-3(2H)-pyridazinones and 6-[4-(1H-imidazol-1-yl)phenyl]-3(2H)-pyridazinones |
-
1981
- 1981-07-31 DE DE19813130252 patent/DE3130252A1/de active Granted
-
1982
- 1982-07-06 IE IE1633/82A patent/IE53469B1/en not_active IP Right Cessation
- 1982-07-08 ZA ZA824882A patent/ZA824882B/xx unknown
- 1982-07-08 AT AT82106110T patent/ATE22445T1/de not_active IP Right Cessation
- 1982-07-08 EP EP82106110A patent/EP0071059B1/de not_active Expired
- 1982-07-12 US US06/397,090 patent/US4504479A/en not_active Expired - Fee Related
- 1982-07-12 GR GR68728A patent/GR76191B/el unknown
- 1982-07-30 DK DK343482A patent/DK157549C/da not_active IP Right Cessation
- 1982-07-30 JP JP57132284A patent/JPS5826885A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
ATE22445T1 (de) | 1986-10-15 |
IE821633L (en) | 1983-01-31 |
DK157549B (da) | 1990-01-22 |
IE53469B1 (en) | 1988-11-23 |
DE3130252A1 (de) | 1983-02-17 |
ZA824882B (en) | 1983-04-27 |
JPS5826885A (ja) | 1983-02-17 |
DK343482A (da) | 1983-02-01 |
US4504479A (en) | 1985-03-12 |
EP0071059B1 (de) | 1986-09-24 |
EP0071059A3 (en) | 1984-03-21 |
GR76191B (da) | 1984-08-03 |
DE3130252C2 (da) | 1989-04-27 |
EP0071059A2 (de) | 1983-02-09 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PBP | Patent lapsed |