DK1567195T3 - Dendrimerkonjugater til selektiv opløsning af proteinaggregater - Google Patents

Dendrimerkonjugater til selektiv opløsning af proteinaggregater

Info

Publication number
DK1567195T3
DK1567195T3 DK03775106.2T DK03775106T DK1567195T3 DK 1567195 T3 DK1567195 T3 DK 1567195T3 DK 03775106 T DK03775106 T DK 03775106T DK 1567195 T3 DK1567195 T3 DK 1567195T3
Authority
DK
Denmark
Prior art keywords
dendrimer
protein
dendrimer conjugates
conjugates
solubilising
Prior art date
Application number
DK03775106.2T
Other languages
English (en)
Inventor
Peter Heegaard
Ulrik Boas
Original Assignee
Upfront Chromatography As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Upfront Chromatography As filed Critical Upfront Chromatography As
Application granted granted Critical
Publication of DK1567195T3 publication Critical patent/DK1567195T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08GMACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G83/00Macromolecular compounds not provided for in groups C08G2/00 - C08G81/00
    • C08G83/002Dendritic macromolecules
    • C08G83/003Dendrimers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/69Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
    • A61K47/6949Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B82NANOTECHNOLOGY
    • B82YSPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nanotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • Polymers & Plastics (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK03775106.2T 2002-11-26 2003-11-26 Dendrimerkonjugater til selektiv opløsning af proteinaggregater DK1567195T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DKPA200201828 2002-11-26
PCT/DK2003/000812 WO2004047869A1 (en) 2002-11-26 2003-11-26 Dendrimer conjugates for selective of protein aggregates

Publications (1)

Publication Number Publication Date
DK1567195T3 true DK1567195T3 (da) 2011-02-14

Family

ID=32337945

Family Applications (1)

Application Number Title Priority Date Filing Date
DK03775106.2T DK1567195T3 (da) 2002-11-26 2003-11-26 Dendrimerkonjugater til selektiv opløsning af proteinaggregater

Country Status (7)

Country Link
US (1) US20060127350A1 (da)
EP (1) EP1567195B1 (da)
AT (1) ATE485839T1 (da)
AU (1) AU2003283205A1 (da)
DE (1) DE60334726D1 (da)
DK (1) DK1567195T3 (da)
WO (1) WO2004047869A1 (da)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7153905B2 (en) * 2003-03-21 2006-12-26 The General Hospital Corporation Hyperbranched dendron and methods of synthesis and use thereof
DE102004040119A1 (de) * 2004-08-18 2006-04-27 Heinrich-Heine-Universität Düsseldorf Mittel zur Therapie und Prävention von Prionenerkrankungen
WO2006102484A2 (en) * 2005-03-21 2006-09-28 Anp Technologies, Inc. Symmetrically branched polymer conjugates and microarray assays
GR1006666B (el) * 2006-07-21 2010-01-19 Εθνικο Κεντρο Ερευνας Φυσικων Επιστημων (Εκεφε) "Δημοκριτος" Μοριακοι δενδριτικοι φορεις με προσαρμοζομενη/μεταβαλλομενη διαλυτοτητα και συμπληρωματικοτητα προς μεμβρανικους υποδοχεις
IL178645A0 (en) * 2006-10-16 2007-02-11 Ariel University Res And Dev C Dendrimeric platform for controlled release of drugs
WO2011001657A1 (ja) 2009-07-01 2011-01-06 独立行政法人科学技術振興機構 ポリイオンデンドリマー、及びそれよりなるハイドロゲル
WO2012065082A1 (en) * 2010-11-11 2012-05-18 Massachusetts Institute Of Technology Dendrimer-based excipients for the attentuation of protein aggregation
CA2824063C (en) * 2011-01-09 2020-02-18 Anp Technologies, Inc. Hydrophobic molecule-induced branched polymer aggregates and their use
US20190015350A1 (en) 2013-02-05 2019-01-17 Anp Technologies, Inc. Nanoparticles Containing a Taxane and their Use
US8883239B2 (en) 2013-02-26 2014-11-11 Universidad De Talca Clarification and selective binding of phenolic compounds from liquid foodstuff or beverages using smart polymers
CA3024333A1 (en) * 2016-05-26 2017-11-30 University Of Idaho A system and method for water treatment
JP7136790B2 (ja) 2017-02-17 2022-09-13 ブリストル-マイヤーズ スクイブ カンパニー アルファ-シヌクレインに対する抗体およびその使用

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3214366A (en) * 1964-07-20 1965-10-26 Standard Oil Co Hydrocarbon conversion process
US4587329A (en) * 1984-08-17 1986-05-06 The Dow Chemical Company Dense star polymers having two dimensional molecular diameter
ATE277640T1 (de) * 1994-03-07 2004-10-15 Dow Chemical Co Bioaktive und/oder gezielte dendrimere-konjugate enthaltend genetisches material
US6719988B2 (en) * 1997-02-21 2004-04-13 The Regents Of The University Of California Antiseptic compositions for inactivating prions
BR0011055A (pt) * 1999-06-01 2002-05-21 Univ California Método de esterilização
PT1251737E (pt) * 2000-01-31 2005-08-31 Univ California Composicoes tratadas para inactivar proteinas infecciosas
MXPA03011455A (es) * 2001-06-22 2004-04-05 Hoffmann La Roche Complejo soluble que comprende glucoproteina de superficie retroviral.
KR20050111586A (ko) * 2003-02-13 2005-11-25 내셔널 센터 포 사이언티픽 리서치 데모크리토스 드러그 및 유전자 전달 시스템으로서의 다기능의 덴드리머및 다중결합된 폴리머

Also Published As

Publication number Publication date
WO2004047869A1 (en) 2004-06-10
ATE485839T1 (de) 2010-11-15
EP1567195A1 (en) 2005-08-31
EP1567195B1 (en) 2010-10-27
US20060127350A1 (en) 2006-06-15
DE60334726D1 (de) 2010-12-09
AU2003283205A1 (en) 2004-06-18

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