DK156392C - Analogifremgangsmaade til fremstilling af aminopropoxyindolderivater - Google Patents

Analogifremgangsmaade til fremstilling af aminopropoxyindolderivater

Info

Publication number
DK156392C
DK156392C DK344280A DK344280A DK156392C DK 156392 C DK156392 C DK 156392C DK 344280 A DK344280 A DK 344280A DK 344280 A DK344280 A DK 344280A DK 156392 C DK156392 C DK 156392C
Authority
DK
Denmark
Prior art keywords
aminopropoxy
preparation
analogy procedure
industrial derivatives
derivatives
Prior art date
Application number
DK344280A
Other languages
English (en)
Other versions
DK156392B (da
DK344280A (da
Inventor
Richard Berthold
Original Assignee
Sandoz Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz Ag filed Critical Sandoz Ag
Publication of DK344280A publication Critical patent/DK344280A/da
Publication of DK156392B publication Critical patent/DK156392B/da
Application granted granted Critical
Publication of DK156392C publication Critical patent/DK156392C/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/08Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/04Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/06Antiarrhythmics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Cardiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Indole Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DK344280A 1979-08-10 1980-08-08 Analogifremgangsmaade til fremstilling af aminopropoxyindolderivater DK156392C (da)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
CH736679 1979-08-10
CH736879 1979-08-10
CH736679 1979-08-10
CH736879 1979-08-10
CH98780 1980-02-07
CH98780 1980-02-07

Publications (3)

Publication Number Publication Date
DK344280A DK344280A (da) 1981-02-11
DK156392B DK156392B (da) 1989-08-14
DK156392C true DK156392C (da) 1990-01-08

Family

ID=27172583

Family Applications (1)

Application Number Title Priority Date Filing Date
DK344280A DK156392C (da) 1979-08-10 1980-08-08 Analogifremgangsmaade til fremstilling af aminopropoxyindolderivater

Country Status (16)

Country Link
US (1) US4361562A (da)
EP (1) EP0025111B1 (da)
JP (1) JPH01230516A (da)
AU (1) AU547149B2 (da)
CA (1) CA1184557A (da)
DE (1) DE3068678D1 (da)
DK (1) DK156392C (da)
ES (1) ES8106291A1 (da)
FI (1) FI75559C (da)
IE (1) IE50186B1 (da)
IL (1) IL60805A (da)
MY (1) MY8700186A (da)
NZ (1) NZ194614A (da)
PH (1) PH15886A (da)
PT (1) PT71676B (da)
YU (1) YU201080A (da)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3200304A1 (de) * 1981-01-16 1982-08-26 Sandoz-Patent-GmbH, 7850 Lörrach 3-aminopropoxyaryl-derivate, ihre herstellung und sie enthaltende arzneimittel
DE3131146A1 (de) * 1981-08-06 1983-02-24 Boehringer Mannheim Gmbh, 6800 Mannheim Neue heteroaryloxypropanolamine, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
FR2523964B1 (fr) * 1982-03-23 1985-09-27 Sanofi Sa Nouveaux derives de la tryptamine actifs notamment sur le systeme cardiovasculaire et procede pour leur preparation
US4558129A (en) * 1983-05-18 1985-12-10 Syntex (U.S.A.) Inc. Benzodioxanyl-hydroxyethylene-piperazinyl acetanilides which effect calcium entry and β-blockade
US4499100A (en) * 1983-05-18 1985-02-12 Syntex (U.S.A.) Inc. Benzodioxanyl-hydroxyethyleneamino-piperidinyl acetanilides, ketones, esters and carbamates which effect immunity and calcium entry and β-blockade
US4567264A (en) * 1983-05-18 1986-01-28 Syntex (U.S.A.) Inc. Cardioselective aryloxy- and arylthio- hydroxypropylene-piperazinyl acetanilides which affect calcium entry
GB2163150B (en) * 1984-07-19 1988-05-25 Sandoz Ltd 3-aminopropoxyaryl derivatives
FR2584713B1 (fr) * 1985-07-11 1988-09-09 Roussel Uclaf Nouveaux derives de l'indole carboxamide, leurs sels, procede et intermediaires de preparation, application a titre de medicaments et compositions les renfermant
FR2589863B1 (fr) * 1985-11-12 1988-07-29 Sanofi Sa Derives d'hydroxy-4 indole, leur procede de preparation et leur utilisation
DE3721260A1 (de) * 1987-06-27 1989-01-12 Beiersdorf Ag Neue indolylpropanole, verfahren zu ihrer herstellung und ihre verwendung sowie die verbindungen enthaltende zubereitungen
US4980351A (en) * 1987-11-04 1990-12-25 Warner-Lambert Company 3-aminopropoxyaryl derivatives having cardiotonic and antihypertensive use and compositions thereof
US5229412A (en) * 1988-03-25 1993-07-20 The Board Of Trustees Of The Leland Stanford Junior University Method for relieving anxiety using 5-hydroxytryptamine-1a-receptor-binding compounds
DE3831993A1 (de) * 1988-09-21 1990-03-29 Basf Ag 2-hydroxy-3-phenoxy-propyl-substituierte piperazine und homo-piperazine, ihre herstellung und verwendung
DE4002391A1 (de) * 1990-01-27 1991-08-01 Beiersdorf Ag Indolylpropanole, verfahren zu ihrer herstellung und ihre verwendung sowie die verbindungen enthaltende zubereitungen
US5215987A (en) * 1990-04-23 1993-06-01 Ortho Pharmaceutical Corporation Substituted benzhydryl 2-hydroxypropyl piperazine derivatives
TW205034B (da) * 1990-09-13 1993-05-01 Pola Kasei Kogyo Kk
US5741789A (en) 1995-01-17 1998-04-21 Eli Lilly And Company Compounds having effects on serotonin-related systems
US5614523A (en) * 1995-01-17 1997-03-25 Eli Lilly And Company Compounds having effects on serotonin-related systems
US5576321A (en) * 1995-01-17 1996-11-19 Eli Lilly And Company Compounds having effects on serotonin-related systems
US5627196A (en) * 1995-01-17 1997-05-06 Eli Lilly And Company Compounds having effects on serotonin-related systems
US5789402A (en) * 1995-01-17 1998-08-04 Eli Lilly Company Compounds having effects on serotonin-related systems
US6408016B1 (en) * 1997-02-24 2002-06-18 At&T Wireless Services, Inc. Adaptive weight update method and system for a discrete multitone spread spectrum communications system
US7144898B2 (en) 1999-12-20 2006-12-05 Eli Lilly And Company Indole derivatives for the treatment of depression and anxiety

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT326107B (de) * 1935-11-15 1975-11-25 Boehringer Sohn Ingelheim Verfahren zur herstellung von neuen racemischen oder optisch aktiven n,n'-bis- (3-subst. phenoxy-2-hydroxy-1-propyl) -alpha,omega- diaminoalkanen sowie deren säureadditionssalzen
US3051709A (en) * 1960-04-22 1962-08-28 Us Vitamin Pharm Corp Substitutedamino-3-(4-and 5-indanoxy)-propane-2-ols
BE626435A (da) * 1961-12-22
NL300886A (da) * 1962-11-23
BE754360A (fr) * 1969-08-05 1971-02-03 Sandoz Sa Nouveaux derives de l'indole, leur preparation et medicaments contenantdes derives
GB1410783A (en) 1972-01-20 1975-10-22 Wyeth John & Brother Ltd N-substituted 4-amidopyridines tetrahydropyridines and piperidines
BE794333A (fr) * 1972-01-20 1973-07-19 Wyeth John & Brother Ltd Composes heterocycliques azotes therapeutiques
US4038279A (en) * 1972-12-23 1977-07-26 Boehringer Ingelheim Gmbh N-aryl-n'-(phenyl-or phenoxy-alkyl)-piperazines and salts thereof
DE2337461A1 (de) * 1973-07-24 1975-02-06 Boehringer Mannheim Gmbh Neue indolderivate und verfahren zu deren herstellung
US4076829A (en) * 1974-11-16 1978-02-28 Boehringer Mannheim Gmbh Aminopropanol compounds and compositions for the treatment of cardiac and circulatory diseases
DE2633839A1 (de) * 1975-08-07 1977-02-24 Sandoz Ag Neue 4-aminopropoxyindolderivate, ihre herstellung und verwendung
DE2651574A1 (de) * 1976-11-12 1978-05-18 Boehringer Mannheim Gmbh Ein neues aminopropanol-derivat und verfahren zu dessen herstellung
DE2830211A1 (de) * 1977-07-21 1979-02-01 Sandoz Ag Substituierte indol-derivate, ihre herstellung und verwendung
DE2960178D1 (en) * 1978-06-06 1981-04-09 Hoechst Ag New substituted phenylpiperazine derivatives, pharmaceutical compositions containing them and process for their preparation
EP0013878A1 (en) * 1979-01-18 1980-08-06 Sandoz Ag 3-Aminopropoxyaryl derivatives, their preparation and pharmaceutical compositions containing them

Also Published As

Publication number Publication date
DK156392B (da) 1989-08-14
MY8700186A (en) 1987-12-31
PH15886A (en) 1983-04-14
DE3068678D1 (en) 1984-08-30
IL60805A0 (en) 1980-10-26
NZ194614A (en) 1984-07-31
AU6119880A (en) 1981-02-12
JPH01230516A (ja) 1989-09-14
PT71676A (en) 1980-09-01
IE50186B1 (en) 1986-03-05
ES494119A0 (es) 1981-08-01
FI75559C (fi) 1988-07-11
CA1184557A (en) 1985-03-26
PT71676B (en) 1981-09-21
ES8106291A1 (es) 1981-08-01
IL60805A (en) 1984-06-29
YU201080A (en) 1983-06-30
IE801655L (en) 1981-02-10
AU547149B2 (en) 1985-10-10
EP0025111A1 (en) 1981-03-18
FI802437A (fi) 1981-02-11
FI75559B (fi) 1988-03-31
DK344280A (da) 1981-02-11
EP0025111B1 (en) 1984-07-25
US4361562A (en) 1982-11-30

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