DK152288C - Analogifremgangsmaade til fremstilling af 3-(1,4-benzodioxan-2-yl-methoxy)-2-propanolaminer eller syreadditionssalte deraf - Google Patents
Analogifremgangsmaade til fremstilling af 3-(1,4-benzodioxan-2-yl-methoxy)-2-propanolaminer eller syreadditionssalte derafInfo
- Publication number
- DK152288C DK152288C DK153581A DK153581A DK152288C DK 152288 C DK152288 C DK 152288C DK 153581 A DK153581 A DK 153581A DK 153581 A DK153581 A DK 153581A DK 152288 C DK152288 C DK 152288C
- Authority
- DK
- Denmark
- Prior art keywords
- benzodioxan
- methoxy
- acid addition
- propanolamines
- preparing
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 3
- 239000002253 acid Substances 0.000 title abstract 2
- 150000003839 salts Chemical class 0.000 title abstract 2
- -1 1,4-BENZODIOXAN-2-YL-METHOXY Chemical class 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- GWQOQQVKVOOHTI-UHFFFAOYSA-N 2,3-dihydro-1,4-benzodioxin-3-ylmethanol Chemical compound C1=CC=C2OC(CO)COC2=C1 GWQOQQVKVOOHTI-UHFFFAOYSA-N 0.000 abstract 1
- KFZMGEQAYNKOFK-UHFFFAOYSA-N 2-propanol Substances CC(C)O KFZMGEQAYNKOFK-UHFFFAOYSA-N 0.000 abstract 1
- BRLQWZUYTZBJKN-UHFFFAOYSA-N Epichlorohydrin Chemical compound ClCC1CO1 BRLQWZUYTZBJKN-UHFFFAOYSA-N 0.000 abstract 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 206010020772 Hypertension Diseases 0.000 abstract 1
- 125000002777 acetyl group Chemical group [H]C([H])([H])C(*)=O 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 206010003119 arrhythmia Diseases 0.000 abstract 1
- 125000003710 aryl alkyl group Chemical group 0.000 abstract 1
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 1
- GYZLOYUZLJXAJU-UHFFFAOYSA-N diglycidyl ether Chemical compound C1OC1COCC1CO1 GYZLOYUZLJXAJU-UHFFFAOYSA-N 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 1
- 125000002924 primary amino group Chemical class [H]N([H])* 0.000 abstract 1
- 238000002560 therapeutic procedure Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D319/10—1,4-Dioxanes; Hydrogenated 1,4-dioxanes
- C07D319/14—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems
- C07D319/16—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D319/20—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring with substituents attached to the hetero ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Cardiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Heart & Thoracic Surgery (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Lubricants (AREA)
- Preventing Corrosion Or Incrustation Of Metals (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR8007719 | 1980-04-04 | ||
| FR8007719A FR2479825A1 (fr) | 1980-04-04 | 1980-04-04 | Benzodioxanne 1,4 methoxy-2 propanolamines, leur preparation et leur application en tant que medicaments |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| DK153581A DK153581A (da) | 1981-10-05 |
| DK152288B DK152288B (da) | 1988-02-15 |
| DK152288C true DK152288C (da) | 1988-07-11 |
Family
ID=9240576
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK153581A DK152288C (da) | 1980-04-04 | 1981-04-03 | Analogifremgangsmaade til fremstilling af 3-(1,4-benzodioxan-2-yl-methoxy)-2-propanolaminer eller syreadditionssalte deraf |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US4456614A (OSRAM) |
| EP (1) | EP0037778B1 (OSRAM) |
| JP (1) | JPS56156275A (OSRAM) |
| AT (1) | ATE5722T1 (OSRAM) |
| AU (1) | AU543364B2 (OSRAM) |
| CA (1) | CA1167047A (OSRAM) |
| DE (1) | DE3161750D1 (OSRAM) |
| DK (1) | DK152288C (OSRAM) |
| ES (1) | ES8201572A1 (OSRAM) |
| FR (1) | FR2479825A1 (OSRAM) |
| ZA (1) | ZA812263B (OSRAM) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2479825A1 (fr) * | 1980-04-04 | 1981-10-09 | Fabre Sa Pierre | Benzodioxanne 1,4 methoxy-2 propanolamines, leur preparation et leur application en tant que medicaments |
| CA1220059A (en) * | 1983-10-03 | 1987-04-07 | Edmund Isakov | Two-prong rotary bit, especially for use with roof drills, and insert therefor |
| ATE182367T1 (de) * | 1992-12-21 | 1999-08-15 | Duphar Int Res | Enzymatisches verfahren zur stereoselektiven herstellung einem enantiomer aus einem hetero bicyclischen alkohols |
| MY147767A (en) * | 2004-06-16 | 2013-01-31 | Janssen Pharmaceutica Nv | Novel sulfamate and sulfamide derivatives useful for the treatment of epilepsy and related disorders |
| TW200612905A (en) * | 2004-06-16 | 2006-05-01 | Janssen Pharmaceutica Nv | Novel sulfamate and sulfamide derivatives useful for the treatment of epilepsy and related disorders |
| CA2578407A1 (en) * | 2004-08-24 | 2006-03-02 | Janssen Pharmaceutica N.V. | Novel benzo-fused heteroaryl sulfamide derivatives useful as anticonvulsant agents |
| MX2007014613A (es) * | 2005-05-20 | 2008-04-02 | Johnson & Johnson | Procedimiento para la preparacion de derivados de sulfamida. |
| US20070155823A1 (en) * | 2005-12-19 | 2007-07-05 | Smith-Swintosky Virginia L | Use of benzo-fused heterocycle sulfamide derivatives as neuroprotective agents |
| US8691867B2 (en) * | 2005-12-19 | 2014-04-08 | Janssen Pharmaceutica Nv | Use of benzo-fused heterocycle sulfamide derivatives for the treatment of substance abuse and addiction |
| US8497298B2 (en) * | 2005-12-19 | 2013-07-30 | Janssen Pharmaceutica Nv | Use of benzo-fused heterocycle sulfamide derivatives for lowering lipids and lowering blood glucose levels |
| US20070155827A1 (en) * | 2005-12-19 | 2007-07-05 | Smith-Swintosky Virginia L | Use of benzo-fused heterocycle sulfamide derivatives for the treatment of depression |
| AR058389A1 (es) * | 2005-12-19 | 2008-01-30 | Janssen Pharmaceutica Nv | Uso de derivados heterociclicos benzo-fusionados de sulfamida para el tratamiento de la obesidad |
| US8716231B2 (en) | 2005-12-19 | 2014-05-06 | Janssen Pharmaceutica Nv | Use of benzo-fused heterocycle sulfamide derivatives for the treatment of pain |
| US8937096B2 (en) * | 2005-12-19 | 2015-01-20 | Janssen Pharmaceutica Nv | Use of benzo-fused heterocyle sulfamide derivatives for the treatment of mania and bipolar disorder |
| EP2026790A2 (en) * | 2006-05-19 | 2009-02-25 | Janssen Pharmaceutica, N.V. | Co-therapy for the treatment of epilepsy and related disorders |
| US20090247618A1 (en) * | 2008-03-26 | 2009-10-01 | Ballentine Scott A | Process for preparation of benzo-fused heteroaryl derivatives |
| US20090247617A1 (en) * | 2008-03-26 | 2009-10-01 | Abdel-Magid Ahmed F | Process for the preparation of benzo-fused heteroaryl sulfamates |
| WO2010008776A2 (en) * | 2008-06-23 | 2010-01-21 | Janssen Pharmaceutica Nv | Disposable patch and reusable sensor assembly for use in medical device localization and mapping systems |
| US8815939B2 (en) * | 2008-07-22 | 2014-08-26 | Janssen Pharmaceutica Nv | Substituted sulfamide derivatives |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL281245A (OSRAM) * | 1962-07-20 | |||
| GB1100960A (en) * | 1963-06-20 | 1968-01-31 | Ward Blenkinsop & Co Ltd | 1,4-benzodioxane derivatives |
| GB1058822A (en) * | 1963-07-30 | 1967-02-15 | Ici Ltd | 3-amino-2-hydroxypropoxy heterocyclic derivatives |
| GB1521471A (en) * | 1974-06-05 | 1978-08-16 | Randall & Son Ltd J | Token-deposit locks |
| FR2358142A1 (fr) * | 1976-07-12 | 1978-02-10 | Parcor | Nouveaux derives du benzodioxanne |
| JPS5377081A (en) * | 1976-12-20 | 1978-07-08 | Yoshitomi Pharmaceut Ind Ltd | 1,4-benzodioxepin derivative, its acid addition salt, and its preparation |
| US4187313A (en) * | 1978-01-30 | 1980-02-05 | Ciba-Geigy Corporation | 2-Aminoethyl-1,4-benzodioxans |
| US4261907A (en) * | 1978-01-30 | 1981-04-14 | Ciba-Geigy Corporation | Stereospecific process |
| FR2479825A1 (fr) * | 1980-04-04 | 1981-10-09 | Fabre Sa Pierre | Benzodioxanne 1,4 methoxy-2 propanolamines, leur preparation et leur application en tant que medicaments |
-
1980
- 1980-04-04 FR FR8007719A patent/FR2479825A1/fr active Granted
-
1981
- 1981-03-28 ES ES500822A patent/ES8201572A1/es not_active Expired
- 1981-04-02 EP EP81400529A patent/EP0037778B1/fr not_active Expired
- 1981-04-02 DE DE8181400529T patent/DE3161750D1/de not_active Expired
- 1981-04-02 AT AT81400529T patent/ATE5722T1/de not_active IP Right Cessation
- 1981-04-02 US US06/250,407 patent/US4456614A/en not_active Expired - Fee Related
- 1981-04-03 JP JP5103681A patent/JPS56156275A/ja active Granted
- 1981-04-03 ZA ZA00812263A patent/ZA812263B/xx unknown
- 1981-04-03 DK DK153581A patent/DK152288C/da not_active IP Right Cessation
- 1981-04-03 CA CA000374619A patent/CA1167047A/fr not_active Expired
- 1981-04-06 AU AU69099/81A patent/AU543364B2/en not_active Ceased
-
1983
- 1983-01-03 US US06/455,125 patent/US4539413A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| ZA812263B (en) | 1982-04-28 |
| US4456614A (en) | 1984-06-26 |
| DK152288B (da) | 1988-02-15 |
| FR2479825A1 (fr) | 1981-10-09 |
| ATE5722T1 (de) | 1984-01-15 |
| EP0037778B1 (fr) | 1983-12-28 |
| ES500822A0 (es) | 1982-01-01 |
| JPS649994B2 (OSRAM) | 1989-02-21 |
| AU6909981A (en) | 1981-10-08 |
| ES8201572A1 (es) | 1982-01-01 |
| FR2479825B1 (OSRAM) | 1983-07-08 |
| DK153581A (da) | 1981-10-05 |
| DE3161750D1 (en) | 1984-02-02 |
| EP0037778A1 (fr) | 1981-10-14 |
| CA1167047A (fr) | 1984-05-08 |
| JPS56156275A (en) | 1981-12-02 |
| US4539413A (en) | 1985-09-03 |
| AU543364B2 (en) | 1985-04-18 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DK152288C (da) | Analogifremgangsmaade til fremstilling af 3-(1,4-benzodioxan-2-yl-methoxy)-2-propanolaminer eller syreadditionssalte deraf | |
| KR850003393A (ko) | 1-벤질-아미노알킬-피롤리디논의 제조방법 | |
| DK471384D0 (da) | Substituerede 2-mercoptoimidazoler og fremgangsmaade til fremstilling deraf | |
| SE7709482L (sv) | Sett att framstella nya 0-(3-amino-2-hydroxipropyl)-amidoximderivat | |
| NO156526C (no) | Analogifremgangsmaate ved fremstilling av terapeutisk aktive 1-fenyl-2-aminocarbonylindol-forbindelser. | |
| BR8300419A (pt) | Emprego de hidroxialquilfenonas e processo para a fotopolimerizacao de compostos etilenicamente insaturados | |
| ES485593A1 (es) | Un procedimiento para la produccion de un derivado de acido fenoxicarboxilico | |
| JPS54122234A (en) | Manufacture of hydroxyphenyl ether | |
| DK372482A (da) | Fremgangsmaade til fremstilling af 1-phenyl-2-piperazinoalkyl-indazol-3-on-forbindelser eller syreadditionssalte deraf og mellemprodukter ved fremgangsmaaden | |
| SE8005127L (sv) | Sett att framstella 15-hydroxiimino-e-homoeburnanderivat | |
| US2996506A (en) | Hcxchb | |
| GB1055184A (en) | A process for the manufacture of 2-styryl-oxazole compounds | |
| JPS5936627B2 (ja) | インダゾ−ル誘導体の製法 | |
| DK158465C (da) | Kontinuerlig fremgangsmaade til fremstilling af dichloracetamider | |
| ATE30718T1 (de) | Herstellung von 1-benzyl azetidin-3-ol und von dem entsprechenden halid acid. | |
| ATE5582T1 (de) | Verfahren zur herstellung von 1-aryloxymethylketonen. | |
| KR890002080A (ko) | 퍼플루오로알킬-함유 에폭사이드 및 이의 제조방법 | |
| FI854718A0 (fi) | Foerfarande foer framstaellning av -hydroxi-alkan-syror och medelst foerfarandet erhaollna foereningar. | |
| GB1353133A (en) | Bisstyryltriazoles their use for the optical brightening of organic materials and process for their manufacture | |
| DK452984D0 (da) | Fremgangsmaade til fremstilling af quinolin-4-oner | |
| ATE42089T1 (de) | Verfahren zur herstellung von bromfluoressigs|ure. | |
| ATE200T1 (de) | Verfahren zur herstellung von alpha, beta-dihalogenalkylisocyanaten. | |
| ES434504A3 (es) | Procedimiento para preparar 2-(morfolino u homomorfolino)-1-(3-trifluormetilfenil)propanos. | |
| SE8305072D0 (sv) | Verfahren zur herstellung von 3,3-diphenyl-1-methyl-propylamin-derivaten und derer seure additionssalze | |
| ES8200877A2 (es) | Procedimiento para la preparacion de nuevos derivados de 1- (3-(3,4,5-trimetoxifenoxi)-2-hidroxi-propil)-4-aril-pipera- zina |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PBP | Patent lapsed |