DK1511843T3 - Screeningsmetoder - Google Patents

Screeningsmetoder

Info

Publication number
DK1511843T3
DK1511843T3 DK03757145T DK03757145T DK1511843T3 DK 1511843 T3 DK1511843 T3 DK 1511843T3 DK 03757145 T DK03757145 T DK 03757145T DK 03757145 T DK03757145 T DK 03757145T DK 1511843 T3 DK1511843 T3 DK 1511843T3
Authority
DK
Denmark
Prior art keywords
host cell
screening methods
methods
screening
phenotype
Prior art date
Application number
DK03757145T
Other languages
English (en)
Inventor
Thomas Jespersen
Morten Bech
Soren Peter Olesen
Jonatan Kutchinsky
Rafael Taboryski
Original Assignee
Sophion Bioscience As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sophion Bioscience As filed Critical Sophion Bioscience As
Application granted granted Critical
Publication of DK1511843T3 publication Critical patent/DK1511843T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034—Isolating an individual clone by screening libraries
    • C12N15/1079—Screening libraries by altering the phenotype or phenotypic trait of the host
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034—Isolating an individual clone by screening libraries
    • C12N15/1082—Preparation or screening gene libraries by chromosomal integration of polynucleotide sequences, HR-, site-specific-recombination, transposons, viral vectors

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Biochemistry (AREA)
  • Plant Pathology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Virology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
DK03757145T 2002-06-07 2003-06-06 Screeningsmetoder DK1511843T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US38639102P 2002-06-07 2002-06-07
DKPA200200869 2002-06-07

Publications (1)

Publication Number Publication Date
DK1511843T3 true DK1511843T3 (da) 2006-07-24

Family

ID=29737850

Family Applications (1)

Application Number Title Priority Date Filing Date
DK03757145T DK1511843T3 (da) 2002-06-07 2003-06-06 Screeningsmetoder

Country Status (9)

Country Link
US (1) US20060121464A1 (da)
EP (1) EP1511843B1 (da)
CN (1) CN100335630C (da)
AT (1) ATE321851T1 (da)
AU (1) AU2003251124A1 (da)
CA (1) CA2488449A1 (da)
DE (1) DE60304345T2 (da)
DK (1) DK1511843T3 (da)
WO (1) WO2003104455A1 (da)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE0400421D0 (sv) * 2004-02-23 2004-02-23 Astrazeneca Ab Assay
US8585881B2 (en) * 2004-09-10 2013-11-19 Onda Via, Inc. Localized chemical microgradients
CN106818295B (zh) * 2017-02-07 2021-05-28 上海市绿化管理指导站 行道树栽植基质、行道树栽植基质的筛选方法及行道树种植系统
EP3864177A4 (en) * 2018-10-10 2022-10-26 The Regents of the University of California DNA METHYLATION-BASED BIOMARKERS FOR LIFE EXPECTANCY AND MORBIDITY

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6936457B1 (en) * 1990-04-03 2005-08-30 Merck & Co., Inc. DNA ENCODING HUMAN α AND β SUBUNITS OF NEURONAL NICOTINIC ACETYLCHOLINE RECEPTOR, CELLS TRANSFORMED THEREWITH, AND RECOMBINANT CELL LINE EXPRESSING A HUMAN α AND β SUBUNIT OF NEURONAL NICOTINIC ACETYLCHOLINE RECEPTOR
EP0877752B1 (en) * 1996-01-23 2003-05-21 The Board Of Trustees Of The Leland Stanford Junior University Methods for screening for transdominant effector peptides and rna molecules
NZ516848A (en) * 1997-06-20 2004-03-26 Ciphergen Biosystems Inc Retentate chromatography apparatus with applications in biology and medicine
US6897031B1 (en) * 1998-04-17 2005-05-24 Rigel Pharmaceuticals, Inc. Multiparameter FACS assays to detect alterations in exocytosis
US6413776B1 (en) * 1998-06-12 2002-07-02 Galapagos Geonomics N.V. High throughput screening of gene function using adenoviral libraries for functional genomics applications
DE19950385A1 (de) * 1999-01-29 2000-08-03 Max Planck Gesellschaft Verfahren zur Isolation von Apoptose-induzierenden DNA-Sequenzen und Detektionssystem
JP4861584B2 (ja) * 1999-10-01 2012-01-25 ソフィオン・バイオサイエンス・アクティーゼルスカブ イオンチャネルの電気生理的性質を測定及び／または監視するための基体及び方法
US6699697B2 (en) * 2000-02-11 2004-03-02 Yale University Planar patch clamp electrodes
WO2001073000A2 (en) * 2000-03-24 2001-10-04 Maxygen, Inc. Methods for modulating cellular and organismal phenotypes
EP1143013A1 (en) * 2000-04-03 2001-10-10 Warner-Lambert Company Methods and compositions for screening Icrac modulators
DK1287134T3 (da) * 2000-06-07 2007-12-03 Ortho Mcneil Pharm Inc Den humane spændings-gatede natriumkanal 1A-subunit og fremgangsmåder til anvendelse deraf
CN1330154A (zh) * 2000-06-27 2002-01-09 南京益来基因医学有限公司 细胞微阵列芯片及其制备方法
EP1311848A2 (en) * 2000-07-07 2003-05-21 Bristol-Myers Squibb Company Electrophysiology configuration suitable for high throughput screening of compounds for drug discovery
US6969449B2 (en) * 2000-07-10 2005-11-29 Vertex Pharmaceuticals (San Diego) Llc Multi-well plate and electrode assemblies for ion channel assays
AU2001287472A1 (en) * 2000-09-19 2002-04-02 Cytion Sa Sample positioning and analysis system
IL155182A0 (en) * 2000-10-02 2003-11-23 Sophion Bioscience As System for electrophysiological measurements

Also Published As

Publication number Publication date
WO2003104455A1 (en) 2003-12-18
US20060121464A1 (en) 2006-06-08
EP1511843B1 (en) 2006-03-29
DE60304345D1 (de) 2006-05-18
DE60304345T2 (de) 2006-11-30
ATE321851T1 (de) 2006-04-15
EP1511843A1 (en) 2005-03-09
CN100335630C (zh) 2007-09-05
CN1665928A (zh) 2005-09-07
AU2003251124A1 (en) 2003-12-22
CA2488449A1 (en) 2003-12-18

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