DK149569C - Analogifremgangsmaade til fremstilling af isoquinolineddikesyre-forbindelser eller farmaceutisk acceptable salte deraf - Google Patents
Analogifremgangsmaade til fremstilling af isoquinolineddikesyre-forbindelser eller farmaceutisk acceptable salte derafInfo
- Publication number
- DK149569C DK149569C DK536480A DK536480A DK149569C DK 149569 C DK149569 C DK 149569C DK 536480 A DK536480 A DK 536480A DK 536480 A DK536480 A DK 536480A DK 149569 C DK149569 C DK 149569C
- Authority
- DK
- Denmark
- Prior art keywords
- analogue
- preparation
- acetic acid
- acceptable salts
- acid compounds
- Prior art date
Links
- GTLGCVNXHYNZLC-UHFFFAOYSA-N acetic acid;isoquinoline Chemical class CC(O)=O.C1=NC=CC2=CC=CC=C21 GTLGCVNXHYNZLC-UHFFFAOYSA-N 0.000 title 1
- 150000003839 salts Chemical class 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/40—Unsaturated compounds
- C07C59/76—Unsaturated compounds containing keto groups
- C07C59/86—Unsaturated compounds containing keto groups containing six-membered aromatic rings and other rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
- C07D217/24—Oxygen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Diabetes (AREA)
- General Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Ophthalmology & Optometry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10493979 | 1979-12-18 | ||
| US06/104,939 US4283539A (en) | 1979-12-18 | 1979-12-18 | Isoquinoline acetic acids |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| DK536480A DK536480A (da) | 1981-06-19 |
| DK149569B DK149569B (da) | 1986-07-28 |
| DK149569C true DK149569C (da) | 1987-02-02 |
Family
ID=22303241
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK536480A DK149569C (da) | 1979-12-18 | 1980-12-17 | Analogifremgangsmaade til fremstilling af isoquinolineddikesyre-forbindelser eller farmaceutisk acceptable salte deraf |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US4283539A (no) |
| EP (1) | EP0030861B1 (no) |
| JP (1) | JPS5692871A (no) |
| DE (1) | DE3064453D1 (no) |
| DK (1) | DK149569C (no) |
| GR (1) | GR72804B (no) |
| IE (1) | IE50524B1 (no) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4761403A (en) * | 1986-04-09 | 1988-08-02 | Abbott Laboratories | Lipoxygenase inhibiting compounds |
| US5771660A (en) * | 1994-12-06 | 1998-06-30 | Sig Schweizerische Industrie-Gesellschaft | Transverse sealing apparatus for a tubular bag packaging machine |
| GB9424842D0 (en) * | 1994-12-09 | 1995-02-08 | British Tech Group | Pharmaceutical compositions |
| ATE404539T1 (de) | 1997-10-02 | 2008-08-15 | Eisai R&D Man Co Ltd | Kondensierte pyridinderivate |
| MXPA02003122A (es) * | 1998-03-31 | 2004-04-21 | Inst For Pharm Discovery Inc | Acidos indolalcanoicos substituidos. |
| TNSN99224A1 (fr) | 1998-12-01 | 2005-11-10 | Inst For Pharm Discovery Inc | Methodes de reduction des niveaux de glucose et triglyceride en serum et pour suppression de l'antigenese utilisant les acides la indolealkanoique |
| US7151102B2 (en) | 2000-10-30 | 2006-12-19 | Kudos Pharmaceuticals Limited | Phthalazinone derivatives |
| ATE355278T1 (de) | 2001-05-08 | 2006-03-15 | Kudos Pharm Ltd | Isochinolinon derivate als parp inhibitoren |
| CA2482806A1 (en) | 2002-04-30 | 2003-11-13 | Kudos Pharmaceuticals Limited | Phthalazinone derivatives |
| AU2003256926A1 (en) * | 2002-07-26 | 2004-02-16 | The Institutes For Pharmaceutical Discovery, Llc | Substituted indolealkanoic acids derivative and formulations containing same for use in treatment of diabetic complications |
| WO2004054979A1 (ja) * | 2002-12-18 | 2004-07-01 | Takeda Pharmaceutical Company Limited | Ｊｎｋ阻害剤 |
| US7449464B2 (en) | 2003-03-12 | 2008-11-11 | Kudos Pharmaceuticals Limited | Phthalazinone derivatives |
| GB0305681D0 (en) | 2003-03-12 | 2003-04-16 | Kudos Pharm Ltd | Phthalazinone derivatives |
| GB0419072D0 (en) | 2004-08-26 | 2004-09-29 | Kudos Pharm Ltd | Phthalazinone derivatives |
| GB0521373D0 (en) | 2005-10-20 | 2005-11-30 | Kudos Pharm Ltd | Pthalazinone derivatives |
| MX2010002749A (es) | 2007-09-14 | 2010-06-25 | Astrazeneca Ab | Derivados de ftalazinona. |
| CA2702429A1 (en) | 2007-10-17 | 2009-04-23 | Kudos Pharmaceuticals Limited | Crystalline form l 4-[3-(4-cyclopropanecarbonyl-piperazine-1-carbonyl)-4-fluoro-benzyl]-2h-phthalazin-1-one |
| AR070221A1 (es) | 2008-01-23 | 2010-03-25 | Astrazeneca Ab | Derivados de ftalazinona inhibidores de polimerasas, composiciones farmaceuticas que los contienen y usos de los mismos para prevenir y/o tratar tumores cancerigenos,lesiones isquemicas y otras enfermedades asociadas. |
| EA020783B1 (ru) | 2008-10-07 | 2015-01-30 | Астразенека Юк Лимитед | Фармацевтическая композиция, содержащая 4-[3-(4-циклопропанкарбонилпиперазин-1-карбонил)-4-фторбензил]-2н-фталазин-1-он и коповидон |
| WO2011162274A1 (ja) * | 2010-06-23 | 2011-12-29 | 大正製薬株式会社 | イソキノリン誘導体 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3821383A (en) * | 1972-07-10 | 1974-06-28 | Ayerst Mckenna & Harrison | Compositions for and a method of treating diabetic complications |
| US4036964A (en) * | 1973-10-11 | 1977-07-19 | Beecham Group Limited | Isocarbostyril-3-carboxylic acid derivatives for the prophylaxis of asthma, hayfever and rhinitis |
-
1979
- 1979-12-18 US US06/104,939 patent/US4283539A/en not_active Expired - Lifetime
-
1980
- 1980-12-15 EP EP80304517A patent/EP0030861B1/en not_active Expired
- 1980-12-15 JP JP17706680A patent/JPS5692871A/ja active Granted
- 1980-12-15 DE DE8080304517T patent/DE3064453D1/de not_active Expired
- 1980-12-16 GR GR63666A patent/GR72804B/el unknown
- 1980-12-17 IE IE2661/80A patent/IE50524B1/en unknown
- 1980-12-17 DK DK536480A patent/DK149569C/da not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| EP0030861B1 (en) | 1983-07-27 |
| IE802661L (en) | 1981-06-18 |
| EP0030861A2 (en) | 1981-06-24 |
| US4283539A (en) | 1981-08-11 |
| EP0030861A3 (en) | 1981-09-23 |
| JPS5692871A (en) | 1981-07-27 |
| DK536480A (da) | 1981-06-19 |
| DE3064453D1 (en) | 1983-09-01 |
| JPS6210508B2 (no) | 1987-03-06 |
| DK149569B (da) | 1986-07-28 |
| IE50524B1 (en) | 1986-04-30 |
| GR72804B (no) | 1983-12-05 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PBP | Patent lapsed |