DK148902C - Analogifremgangsmaade til fremstilling af trh-analoge derivater af n-substitueret histidylprolinamid eller farmaceutisk anvendelige syreadditionssalte heraf - Google Patents

Analogifremgangsmaade til fremstilling af trh-analoge derivater af n-substitueret histidylprolinamid eller farmaceutisk anvendelige syreadditionssalte heraf

Info

Publication number
DK148902C
DK148902C DK157077A DK157077A DK148902C DK 148902 C DK148902 C DK 148902C DK 157077 A DK157077 A DK 157077A DK 157077 A DK157077 A DK 157077A DK 148902 C DK148902 C DK 148902C
Authority
DK
Denmark
Prior art keywords
analogue
prolinamide
trh
preparation
acid addition
Prior art date
Application number
DK157077A
Other languages
Danish (da)
English (en)
Other versions
DK148902B (da
DK157077A (da
Inventor
Eberhard Schwertner
Leopold Albert Norbert Flohe
Siegfried Herrling
Original Assignee
Gruenenthal Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gruenenthal Gmbh filed Critical Gruenenthal Gmbh
Publication of DK157077A publication Critical patent/DK157077A/da
Publication of DK148902B publication Critical patent/DK148902B/da
Application granted granted Critical
Publication of DK148902C publication Critical patent/DK148902C/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06Dipeptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08Tripeptides
    • C07K5/0821Tripeptides with the first amino acid being heterocyclic, e.g. His, Pro, Trp
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/26Psychostimulants, e.g. nicotine, cocaine

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Psychiatry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK157077A 1976-04-09 1977-04-06 Analogifremgangsmaade til fremstilling af trh-analoge derivater af n-substitueret histidylprolinamid eller farmaceutisk anvendelige syreadditionssalte heraf DK148902C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE2615455A DE2615455C2 (de) 1976-04-09 1976-04-09 N-Acyl-L-histidyl-L-prolin (N-substituierte)-amide, Verfahren zu deren Herstellung und diese Verbindungen enthaltende pharmazeutische Zubereitungen
DE2615455 1976-04-09

Publications (3)

Publication Number Publication Date
DK157077A DK157077A (da) 1977-10-10
DK148902B DK148902B (da) 1985-11-11
DK148902C true DK148902C (da) 1986-06-09

Family

ID=5974903

Family Applications (1)

Application Number Title Priority Date Filing Date
DK157077A DK148902C (da) 1976-04-09 1977-04-06 Analogifremgangsmaade til fremstilling af trh-analoge derivater af n-substitueret histidylprolinamid eller farmaceutisk anvendelige syreadditionssalte heraf

Country Status (17)

Country Link
JP (1) JPS52125166A (xx)
AT (1) AT352921B (xx)
AU (1) AU2322677A (xx)
BE (1) BE853444A (xx)
CA (1) CA1088520A (xx)
CH (1) CH632737A5 (xx)
DE (1) DE2615455C2 (xx)
DK (1) DK148902C (xx)
ES (1) ES457563A1 (xx)
FR (1) FR2347338A1 (xx)
GB (1) GB1564078A (xx)
IE (1) IE44485B1 (xx)
NL (1) NL7703789A (xx)
PT (1) PT66283B (xx)
SE (1) SE427835B (xx)
YU (1) YU85977A (xx)
ZA (1) ZA771097B (xx)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE58849B1 (en) * 1984-12-18 1993-11-17 Gruenenthal Chemie Use of dipeptide derivatives for the manufacture of medicaments for the treatment of patients with amyotrophic lateral sclerosis
DE3502041A1 (de) 1985-01-23 1986-07-24 Grünenthal GmbH, 5190 Stolberg Verwendung von dipeptidderivaten zur behandlung posttraumatischer nervenschaeden
JPS63316724A (ja) * 1987-06-19 1988-12-26 Nippon Shinyaku Co Ltd 抗けいれん剤
US5151497A (en) * 1989-02-21 1992-09-29 Japan Tobacco Inc. Histidyl peptide derivatives
WO1996008265A1 (en) * 1994-09-12 1996-03-21 The Trustees Of The University Of Pennsylvania Corticotropin release inhibiting factor and methods of using same
US6039956A (en) * 1994-09-12 2000-03-21 Pennsylvania, Trustees Of The University Of, The Corticotropin release inhibiting factor and methods of using same for treating behavioral symptoms in an anxiety disorder

Also Published As

Publication number Publication date
BE853444A (fr) 1977-08-01
ES457563A1 (es) 1978-03-16
IE44485B1 (en) 1981-12-16
YU85977A (en) 1982-10-31
ATA113977A (de) 1979-03-15
FR2347338B1 (xx) 1980-07-11
SE427835B (sv) 1983-05-09
DK148902B (da) 1985-11-11
NL7703789A (nl) 1977-10-11
CH632737A5 (en) 1982-10-29
SE7704088L (sv) 1977-10-10
PT66283B (de) 1978-08-09
IE44485L (en) 1977-10-09
CA1088520A (en) 1980-10-28
JPS52125166A (en) 1977-10-20
PT66283A (de) 1977-04-01
AT352921B (de) 1979-10-10
DE2615455C2 (de) 1985-06-20
DK157077A (da) 1977-10-10
JPS6110479B2 (xx) 1986-03-29
DE2615455A1 (de) 1977-10-20
GB1564078A (en) 1980-04-02
ZA771097B (en) 1978-01-25
FR2347338A1 (fr) 1977-11-04
AU2322677A (en) 1978-09-21

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