DK147784A - Substituerede piperazin-1-yl-eddikesyreamider, fremgangsmaade til fremstilling deraf samt deres anvendelse som laegemidler - Google Patents
Substituerede piperazin-1-yl-eddikesyreamider, fremgangsmaade til fremstilling deraf samt deres anvendelse som laegemidler Download PDFInfo
- Publication number
- DK147784A DK147784A DK147784A DK147784A DK147784A DK 147784 A DK147784 A DK 147784A DK 147784 A DK147784 A DK 147784A DK 147784 A DK147784 A DK 147784A DK 147784 A DK147784 A DK 147784A
- Authority
- DK
- Denmark
- Prior art keywords
- manufacture
- liquid
- application
- plate
- gas
- Prior art date
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/81—Amides; Imides
- C07D213/82—Amides; Imides in position 3
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/16—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
- C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
- C07D295/182—Radicals derived from carboxylic acids
- C07D295/192—Radicals derived from carboxylic acids from aromatic carboxylic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
- C07D295/20—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carbonic acid, or sulfur or nitrogen analogues thereof
- C07D295/205—Radicals derived from carbonic acid
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
- C07D295/20—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carbonic acid, or sulfur or nitrogen analogues thereof
- C07D295/215—Radicals derived from nitrogen analogues of carbonic acid
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/56—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D307/68—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Neurosurgery (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- Hospice & Palliative Care (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Psychiatry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19833315424 DE3315424A1 (de) | 1983-04-28 | 1983-04-28 | Substituierte piperazin-1-yl-essigsaeure-amide, verfahren zu ihrer herstellung und ihre verwendung |
Publications (2)
Publication Number | Publication Date |
---|---|
DK147784D0 DK147784D0 (da) | 1984-02-29 |
DK147784A true DK147784A (da) | 1984-10-29 |
Family
ID=6197594
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK147784A DK147784A (da) | 1983-04-28 | 1984-02-29 | Substituerede piperazin-1-yl-eddikesyreamider, fremgangsmaade til fremstilling deraf samt deres anvendelse som laegemidler |
Country Status (19)
Country | Link |
---|---|
US (1) | US4610984A (es) |
EP (1) | EP0123977A1 (es) |
JP (1) | JPS59205363A (es) |
KR (1) | KR840008347A (es) |
AU (1) | AU2747384A (es) |
CA (1) | CA1202304A (es) |
CS (2) | CS244849B2 (es) |
DD (1) | DD223711A5 (es) |
DE (1) | DE3315424A1 (es) |
DK (1) | DK147784A (es) |
ES (1) | ES532011A0 (es) |
FI (1) | FI841461A (es) |
GR (1) | GR81494B (es) |
HU (1) | HUT34178A (es) |
IL (1) | IL71657A0 (es) |
NO (1) | NO841464L (es) |
PL (2) | PL253669A1 (es) |
PT (1) | PT78488B (es) |
ZA (1) | ZA843138B (es) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB8512163D0 (en) * | 1985-05-14 | 1985-06-19 | Fujisawa Pharmaceutical Co | Oxothiazolidine compound |
US5110929A (en) * | 1986-08-07 | 1992-05-05 | Medice Cham.-Pharm. Fabrik Putter Gmbh & Co. Kg | Process for the preparation of N-alkylated quaternary nitrogen containing aromatic heterocycles |
IT1249728B (it) * | 1991-11-06 | 1995-03-09 | Sigma Tau Ind Farmaceuti | Derivati delle prolinammide quali attivatori della memoria e dei processi di apprendimento e composizioni farmaceutiche che li contengono |
DE19904710A1 (de) * | 1999-02-05 | 2000-08-10 | Aventis Pharma Gmbh | Substituierte 4-Amino-2-aryl-tetrahydrochinazoline, ihre Herstellung, ihre Verwendung und sie enthaltende pharmazeutische Präparate |
US7851474B2 (en) * | 2005-08-02 | 2010-12-14 | Neurogen Corporation | Dipiperazinyl ketones and related analogues |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2081564A1 (en) * | 1970-03-05 | 1971-12-10 | Delalande Sa | N-amino carbonyl-piperazines analgesics - antiinflammatories ,hypotensives and spasmolytics |
BE774447A (fr) * | 1970-11-11 | 1972-02-14 | Biasedra Lab | Nouveaux derives de la salicylamide et leur application en therapeutique |
US4247549A (en) * | 1978-12-27 | 1981-01-27 | Ici Americas Inc. | Piperazine-1-carboxylic acid esters possessing antidepressant or analgesic activity |
AU535498B2 (en) * | 1981-05-08 | 1984-03-22 | Otsuka Pharmaceutical Co., Ltd. | Aniline derivatives, process for their preparation, and cardiotonics |
-
1983
- 1983-04-28 DE DE19833315424 patent/DE3315424A1/de not_active Withdrawn
-
1984
- 1984-02-29 DK DK147784A patent/DK147784A/da not_active IP Right Cessation
- 1984-04-11 EP EP84104042A patent/EP0123977A1/de not_active Ceased
- 1984-04-12 FI FI841461A patent/FI841461A/fi not_active Application Discontinuation
- 1984-04-12 NO NO841464A patent/NO841464L/no unknown
- 1984-04-18 US US06/601,637 patent/US4610984A/en not_active Expired - Fee Related
- 1984-04-23 JP JP59080360A patent/JPS59205363A/ja active Pending
- 1984-04-25 DD DD84262312A patent/DD223711A5/de unknown
- 1984-04-25 CS CS851217A patent/CS244849B2/cs unknown
- 1984-04-25 CS CS843071A patent/CS244811B2/cs unknown
- 1984-04-26 GR GR74523A patent/GR81494B/el unknown
- 1984-04-26 HU HU841608A patent/HUT34178A/hu unknown
- 1984-04-26 PL PL25366984A patent/PL253669A1/xx unknown
- 1984-04-26 PL PL24741484A patent/PL247414A1/xx unknown
- 1984-04-26 PT PT78488A patent/PT78488B/pt unknown
- 1984-04-26 IL IL71657A patent/IL71657A0/xx unknown
- 1984-04-27 ES ES532011A patent/ES532011A0/es active Granted
- 1984-04-27 AU AU27473/84A patent/AU2747384A/en not_active Abandoned
- 1984-04-27 ZA ZA843138A patent/ZA843138B/xx unknown
- 1984-04-27 CA CA000452963A patent/CA1202304A/en not_active Expired
- 1984-04-28 KR KR1019840002290A patent/KR840008347A/ko not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
FI841461A (fi) | 1984-10-29 |
DE3315424A1 (de) | 1984-12-20 |
PT78488A (de) | 1984-05-01 |
AU2747384A (en) | 1984-11-01 |
ES8502103A1 (es) | 1984-12-16 |
EP0123977A1 (de) | 1984-11-07 |
IL71657A0 (en) | 1984-07-31 |
PL247414A1 (en) | 1985-10-08 |
HUT34178A (en) | 1985-02-28 |
DK147784D0 (da) | 1984-02-29 |
NO841464L (no) | 1984-10-29 |
ZA843138B (en) | 1984-11-28 |
DD223711A5 (de) | 1985-06-19 |
PT78488B (de) | 1986-05-22 |
CS244811B2 (en) | 1986-08-14 |
CS244849B2 (en) | 1986-08-14 |
GR81494B (es) | 1984-12-11 |
KR840008347A (ko) | 1984-12-14 |
ES532011A0 (es) | 1984-12-16 |
US4610984A (en) | 1986-09-09 |
PL253669A1 (en) | 1986-02-11 |
FI841461A0 (fi) | 1984-04-12 |
CS121785A2 (en) | 1985-09-17 |
CS307184A2 (en) | 1985-09-17 |
JPS59205363A (ja) | 1984-11-20 |
CA1202304A (en) | 1986-03-25 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
ATS | Application withdrawn | ||
PBP | Patent lapsed |