DK144011C - Fremgangsmaade til fremstilling af heteroaromatiske urinstofderivater - Google Patents

Fremgangsmaade til fremstilling af heteroaromatiske urinstofderivater

Info

Publication number
DK144011C
DK144011C DK180378A DK180378A DK144011C DK 144011 C DK144011 C DK 144011C DK 180378 A DK180378 A DK 180378A DK 180378 A DK180378 A DK 180378A DK 144011 C DK144011 C DK 144011C
Authority
DK
Denmark
Prior art keywords
heteroaromatic
procedure
preparation
urinary
derivatives
Prior art date
Application number
DK180378A
Other languages
Danish (da)
English (en)
Other versions
DK180378A (da
DK144011B (da
Inventor
Y Makisumi
T Sasatani
Original Assignee
Shionogi & Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shionogi & Co filed Critical Shionogi & Co
Publication of DK180378A publication Critical patent/DK180378A/da
Publication of DK144011B publication Critical patent/DK144011B/da
Application granted granted Critical
Publication of DK144011C publication Critical patent/DK144011C/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72—Nitrogen atoms
    • C07D213/75—Amino or imino radicals, acylated by carboxylic or carbonic acids, or by sulfur or nitrogen analogues thereof, e.g. carbamates
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
    • C07D261/02—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
    • C07D261/06—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members
    • C07D261/10—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D261/14—Nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D275/00—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings
    • C07D275/02—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings not condensed with other rings
    • C07D275/03—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings not condensed with other rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/38—Nitrogen atoms
    • C07D277/44—Acylated amino or imino radicals
    • C07D277/48—Acylated amino or imino radicals by radicals derived from carbonic acid, or sulfur or nitrogen analogues thereof, e.g. carbonylguanidines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
    • C07D277/62—Benzothiazoles
    • C07D277/68—Benzothiazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D277/82—Nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pyridine Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
DK180378A 1977-04-28 1978-04-25 Fremgangsmaade til fremstilling af heteroaromatiske urinstofderivater DK144011C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP4962977 1977-04-28
JP52049629A JPS6033109B2 (ja) 1977-04-28 1977-04-28 尿素誘導体の合成法

Publications (3)

Publication Number Publication Date
DK180378A DK180378A (da) 1978-10-29
DK144011B DK144011B (da) 1981-11-16
DK144011C true DK144011C (da) 1982-04-26

Family

ID=12836505

Family Applications (1)

Application Number Title Priority Date Filing Date
DK180378A DK144011C (da) 1977-04-28 1978-04-25 Fremgangsmaade til fremstilling af heteroaromatiske urinstofderivater

Country Status (25)

Country Link
US (1) US4183856A (cs)
JP (1) JPS6033109B2 (cs)
AR (1) AR225666A1 (cs)
AU (1) AU513688B2 (cs)
BE (1) BE866581A (cs)
BG (1) BG33278A3 (cs)
BR (1) BR7802618A (cs)
CA (1) CA1093081A (cs)
CH (1) CH633542A5 (cs)
CS (1) CS198297B2 (cs)
DD (1) DD135905A5 (cs)
DE (1) DE2818947A1 (cs)
DK (1) DK144011C (cs)
ES (1) ES468897A1 (cs)
FR (1) FR2388802A1 (cs)
GB (1) GB1572976A (cs)
HU (1) HU176881B (cs)
IE (1) IE46769B1 (cs)
IL (1) IL54468A0 (cs)
IT (1) IT1111465B (cs)
NL (1) NL183513C (cs)
PL (1) PL110681B1 (cs)
SE (1) SE442867B (cs)
SU (1) SU1091853A3 (cs)
YU (1) YU40334B (cs)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8422461D0 (en) * 1984-09-05 1984-10-10 Wyeth John & Brother Ltd Pyridine derivatives
US4808722A (en) * 1985-10-31 1989-02-28 Fmc Corporation Pyridinylurea N-oxide compounds and agricultural uses
DK0427963T3 (da) * 1989-11-10 1994-05-02 Agrolinz Agrarchemikalien Fremgangsmåde til fremstilling af rene, asymmetrisk disubstituerede urinstoffer
DE3940261A1 (de) * 1989-12-06 1991-06-13 Agrolinz Agrarchemikalien Muen Verfahren zur herstellung reiner, unsymmetrisch disubstituierter harnstoffe
EP1458382A1 (en) * 2001-12-21 2004-09-22 Novo Nordisk A/S Amide derivatives as gk activators
KR101116627B1 (ko) * 2002-06-27 2012-10-09 노보 노르디스크 에이/에스 치료제로서 아릴 카르보닐 유도체
DK1723128T3 (da) * 2004-01-06 2013-02-18 Novo Nordisk As Heteroarylurinstoffer og deres anvendelse som glucokinaseaktivatorer
ES2382815T3 (es) * 2005-07-08 2012-06-13 Novo Nordisk A/S Dicicloalquilcarbamoil ureas como activadores de glucoquinasa
MX2008000294A (es) * 2005-07-08 2008-04-04 Novo Nordisk As Activadores de dicicloalquil urea glucocinasa.
RU2443691C2 (ru) * 2005-07-14 2012-02-27 Транстех Фарма, Инк. Мочевинные активаторы глюкокиназы
EP2118083A1 (en) * 2007-01-09 2009-11-18 Novo Nordisk A/S Urea glucokinase activators
CA2675111C (en) * 2007-01-11 2016-04-05 Novo Nordisk A\S Urea glucokinase activators
CA3093025A1 (en) 2018-06-12 2019-12-19 Vtv Therapeutics Llc Therapeutic uses of glucokinase activators in combination with insulin or insulin analogs
US12391658B2 (en) 2020-02-18 2025-08-19 Vtv Therapeutics Llc Sulfoxide and sulfone glucokinase activators and methods of use thereof

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2755285A (en) * 1956-07-17 I-xsubstituted
US2756135A (en) * 1955-07-13 1956-07-24 Du Pont 1-methyl-3-(2-benzothiazolyl)-ureas and their use as herbicides
DE1209801B (de) * 1963-05-11 1966-01-27 Bayer Ag Unkrautbekaempfung in Rueben
US3293257A (en) * 1964-09-14 1966-12-20 United States Borax Chem Pyridyl urea compounds
FR1533184A (fr) * 1965-04-06 1968-07-19 Pechiney Saint Gobain Dérivés du thiazole
DE1620448C3 (de) * 1965-05-08 1974-08-29 Schering Ag, 1000 Berlin Und 4619 Bergkamen Harnstoff- bzw. Thioharnstoffderivate des 3-Methylisothiazols
US3622593A (en) * 1967-08-09 1971-11-23 Fmc Corp 1,1-dimethyl-3-(isothiazol-5-yl)urea
US3547940A (en) * 1967-10-31 1970-12-15 Du Pont Substituted ureido isoxazoles
GB1266769A (cs) * 1969-08-15 1972-03-15
US4062861A (en) * 1973-07-27 1977-12-13 Shionogi & Co., Ltd. 3-Isoxazolylurea derivatives
JPS5031039A (cs) * 1973-07-27 1975-03-27
US4013706A (en) * 1973-11-14 1977-03-22 Sucreries Du Soissonnais Et Compagnie Sucriere Derivatives of substituted urea, acyl ureas, and sulphonyl ureas, and a process for producing the same
US4046770A (en) * 1974-08-30 1977-09-06 Eli Lilly And Company N-(6-acyloxybenzothiazol-2-yl)-N'-phenyl (or substituted phenyl)ureas
JPS5810361B2 (ja) * 1974-10-04 1983-02-25 塩野義製薬株式会社 ３−アルチルイソオキサゾ−ル系除草剤

Also Published As

Publication number Publication date
ES468897A1 (es) 1978-11-16
SU1091853A3 (ru) 1984-05-07
AU3546878A (en) 1979-11-01
YU40334B (en) 1985-12-31
JPS6033109B2 (ja) 1985-08-01
GB1572976A (en) 1980-08-13
CS198297B2 (en) 1980-05-30
IT1111465B (it) 1986-01-13
HU176881B (en) 1981-05-28
NL7804550A (nl) 1978-10-31
CH633542A5 (de) 1982-12-15
AU513688B2 (en) 1980-12-18
DE2818947C2 (cs) 1991-08-22
YU103778A (en) 1982-10-31
FR2388802A1 (fr) 1978-11-24
BG33278A3 (en) 1983-01-14
DK180378A (da) 1978-10-29
DK144011B (da) 1981-11-16
BE866581A (fr) 1978-08-14
BR7802618A (pt) 1979-04-03
SE7804596L (sv) 1978-10-29
NL183513B (nl) 1988-06-16
PL110681B1 (en) 1980-07-31
IL54468A0 (en) 1978-07-31
DE2818947A1 (de) 1978-11-02
US4183856A (en) 1980-01-15
IT7867959A0 (it) 1978-04-27
AR225666A1 (es) 1982-04-15
CA1093081A (en) 1981-01-06
JPS53135972A (en) 1978-11-28
IE46769B1 (en) 1983-09-21
NL183513C (nl) 1988-11-16
SE442867B (sv) 1986-02-03
IE780707L (en) 1978-10-28
DD135905A5 (de) 1979-06-06
PL206450A1 (pl) 1979-03-26
FR2388802B1 (cs) 1980-04-04

Similar Documents

Publication Publication Date Title
DK63178A (da) Fremgangsmaade til fremstilling af pyrrodinderivater
DK148280C (da) Analogifremgangsmaade til fremstilling af thienothiazinderivater
DK155367C (da) Analogifremgangsmaade til fremstilling af 2-nitroimidazolderivater
DK536178A (da) Fremgangsmaade til fremstilling af stilbenderivater
DK129578A (da) Fremgangsmaade til fremstilling af oximderivater af 3-acetoxymethyl-7-aminothiazolylacetamidocephalosporansyre
DK481778A (da) Fremgangsmaade til fremstilling af urinstofderivater
DK153482C (da) Analogifremgangsmaade til fremstilling af 5-cyano-prostacyklinderivater
DK442778A (da) Fremgangsmaade til fremstilling af pyrrolderivater
DK144011C (da) Fremgangsmaade til fremstilling af heteroaromatiske urinstofderivater
DK154137C (da) Analogifremgangsmaade til fremstilling af meta-sulfonamido-benzamidderivater
DK129678A (da) Fremgangsmaade til fremstilling af oximderivater af 7-aminothiazolylacetamidocephalosporansyre
DK30578A (da) Fremgangsmaade til fremstilling af aminoalkoxyphenylderivater
DK50778A (da) Fremgangsmaade til fremstilling af oxadiazolopyrimidinderivater
DK6078A (da) Fremgangsmaade til fremstilling af aminosubstituerede umaettede nitrogenholdige heterocycliske forbindelser
DK155285C (da) Fremgangsmaade til fremstilling af thienopyridinderivater
DK50878A (da) Fremgangsmaade til fremstilling af oxadiazolopyrimidinderivater
DK68978A (da) Fremgangsmaade til fremstilling af oximderivater af 3-thiadiazolythiomethyl-7-aminothiazolylacetamidocephalosporansyre
DK323978A (da) Fremgangsmaade til fremstilling af thiophenerivater
DK246878A (da) Fremgangsmaade til fremstilling af acylderivater
DK44278A (da) Fremgangsmaade til fremstilling af thiophenderivater
DK61778A (da) Fremgangsmaade til fremstilling af everninominderivater
DK214678A (da) Fremgangsmaade til fremstilling af benzazepinderivater
DK553378A (da) Fremgangsmaade til fremstilling af 1-hydrocarbylpyrrol-2-eddikesyrederivater
DK243178A (da) Fremgangsmaade til fremstilling af guanidinderivater
DK147072C (da) Analogifremgangsmaade til fremstilling af ergolenderivater

Legal Events

Date Code Title Description
PBP Patent lapsed