DK1428530T3 - Tetrapeptidderivatkrystaller - Google Patents

Tetrapeptidderivatkrystaller

Info

Publication number
DK1428530T3
DK1428530T3 DK02799487T DK02799487T DK1428530T3 DK 1428530 T3 DK1428530 T3 DK 1428530T3 DK 02799487 T DK02799487 T DK 02799487T DK 02799487 T DK02799487 T DK 02799487T DK 1428530 T3 DK1428530 T3 DK 1428530T3
Authority
DK
Denmark
Prior art keywords
derivative crystals
tetrapeptide derivative
methoxy
methyl
crystals
Prior art date
Application number
DK02799487T
Other languages
Danish (da)
English (en)
Inventor
Koichi Miyazaki
Katsuyuki Keino
Arihiro Kanada
Nobuyoshi Minami
Original Assignee
Aska Pharm Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aska Pharm Co Ltd filed Critical Aska Pharm Co Ltd
Application granted granted Critical
Publication of DK1428530T3 publication Critical patent/DK1428530T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/08Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10Tetrapeptides
    • C07K5/1002Tetrapeptides with the first amino acid being neutral
    • C07K5/1005Tetrapeptides with the first amino acid being neutral and aliphatic
    • C07K5/101Tetrapeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms, e.g. Val, Ile, Leu
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/0205Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -NH-(X)3-C(=0)-, e.g. statine or derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK02799487T 2001-09-20 2002-09-19 Tetrapeptidderivatkrystaller DK1428530T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2001286674 2001-09-20
PCT/JP2002/009628 WO2003026645A1 (fr) 2001-09-20 2002-09-19 Cristaux d'un derive de tetrapeptide

Publications (1)

Publication Number Publication Date
DK1428530T3 true DK1428530T3 (da) 2008-12-01

Family

ID=19109609

Family Applications (1)

Application Number Title Priority Date Filing Date
DK02799487T DK1428530T3 (da) 2001-09-20 2002-09-19 Tetrapeptidderivatkrystaller

Country Status (12)

Country Link
US (2) US7008928B2 (ko)
EP (1) EP1428530B1 (ko)
JP (1) JP4060794B2 (ko)
KR (1) KR100901096B1 (ko)
CN (2) CN1834088A (ko)
AT (1) ATE405578T1 (ko)
AU (1) AU2002362579B2 (ko)
CA (1) CA2460956C (ko)
DE (1) DE60228459D1 (ko)
DK (1) DK1428530T3 (ko)
ES (1) ES2309233T3 (ko)
WO (1) WO2003026645A1 (ko)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006068768A2 (en) * 2004-11-24 2006-06-29 Hanna Skubatch Methods and compositions for treating conditions
US7557088B2 (en) * 2006-03-28 2009-07-07 Neopro Labs, Llc Methods and compositions for treating conditions
JP2010527377A (ja) * 2007-05-17 2010-08-12 ネオプロ ラブス,エルエルシー ペプチドの結晶形および非結晶形
WO2009012472A2 (en) * 2007-07-18 2009-01-22 Neopro Labs, Llc Methods and compositions for treating conditions
AU2016297786A1 (en) * 2015-07-24 2018-02-08 Noeleen Melody Quinstatin compounds

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4978744A (en) * 1989-01-27 1990-12-18 Arizona Board Of Regents Synthesis of dolastatin 10
DK0934950T3 (da) * 1991-08-09 2002-07-29 Teikoku Hormone Mfg Co Ltd Tetrapeptidderivat
US6034065A (en) * 1992-12-03 2000-03-07 Arizona Board Of Regents Elucidation and synthesis of antineoplastic tetrapeptide phenethylamides of dolastatin 10

Also Published As

Publication number Publication date
JP4060794B2 (ja) 2008-03-12
WO2003026645A1 (fr) 2003-04-03
KR100901096B1 (ko) 2009-06-08
DE60228459D1 (de) 2008-10-02
CA2460956A1 (en) 2003-04-03
US20040254343A1 (en) 2004-12-16
US20050267041A1 (en) 2005-12-01
AU2002362579B2 (en) 2007-09-06
EP1428530B1 (en) 2008-08-20
CA2460956C (en) 2010-12-21
ATE405578T1 (de) 2008-09-15
WO2003026645A8 (fr) 2004-09-30
KR20040036922A (ko) 2004-05-03
EP1428530A4 (en) 2005-03-30
CN1834088A (zh) 2006-09-20
US7385029B2 (en) 2008-06-10
JPWO2003026645A1 (ja) 2005-01-06
EP1428530A1 (en) 2004-06-16
US7008928B2 (en) 2006-03-07
EP1428530A8 (en) 2005-01-26
CN1309413C (zh) 2007-04-11
CN1556701A (zh) 2004-12-22
ES2309233T3 (es) 2008-12-16

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