DK1423357T3 - Urinstofderivater med antiproteolytisk aktivitet - Google Patents
Urinstofderivater med antiproteolytisk aktivitetInfo
- Publication number
- DK1423357T3 DK1423357T3 DK02758230T DK02758230T DK1423357T3 DK 1423357 T3 DK1423357 T3 DK 1423357T3 DK 02758230 T DK02758230 T DK 02758230T DK 02758230 T DK02758230 T DK 02758230T DK 1423357 T3 DK1423357 T3 DK 1423357T3
- Authority
- DK
- Denmark
- Prior art keywords
- compounds
- formula
- factor viia
- urea derivatives
- present
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C275/28—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
- C07C275/42—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton being further substituted by carboxyl groups
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D333/38—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/14—The ring being saturated
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Cosmetics (AREA)
- Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
- Furan Compounds (AREA)
- Pyridine Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP01115353A EP1270551A1 (en) | 2001-06-26 | 2001-06-26 | Urea derivatives with antiproteolytic activity |
Publications (1)
Publication Number | Publication Date |
---|---|
DK1423357T3 true DK1423357T3 (da) | 2007-01-15 |
Family
ID=8177820
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK02758230T DK1423357T3 (da) | 2001-06-26 | 2002-06-12 | Urinstofderivater med antiproteolytisk aktivitet |
Country Status (14)
Country | Link |
---|---|
US (1) | US6706715B2 (da) |
EP (2) | EP1270551A1 (da) |
JP (1) | JP4231403B2 (da) |
AT (1) | ATE338746T1 (da) |
AU (1) | AU2002325238A1 (da) |
CA (1) | CA2451206C (da) |
CY (1) | CY1105751T1 (da) |
DE (1) | DE60214569T2 (da) |
DK (1) | DK1423357T3 (da) |
ES (1) | ES2269750T3 (da) |
MX (1) | MXPA03011022A (da) |
PE (1) | PE20030133A1 (da) |
PT (1) | PT1423357E (da) |
WO (1) | WO2003002524A2 (da) |
Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1845753A (zh) * | 2003-08-14 | 2006-10-11 | 诺和诺德医疗保健公司 | 因子ⅶ多肽类的含水液体药物组合物 |
BRPI0510295A (pt) | 2004-05-04 | 2007-11-06 | Novo Nordisk Healthcare Ag | preparação de uma glicoproteìna, e, método para produzir a mesma |
AU2005245399A1 (en) * | 2004-05-12 | 2005-12-01 | Schering Corporation | CXCR1 and CXCR2 chemokine antagonists |
JP2008531525A (ja) * | 2005-02-24 | 2008-08-14 | ノボ ノルディスク ヘルス ケア アクチェンゲゼルシャフト | Vii因子ポリペプチド製剤を安定化する化合物 |
EP1893632B1 (en) | 2005-06-17 | 2015-08-12 | Novo Nordisk Health Care AG | Selective reduction and derivatization of engineered factor vii proteins comprising at least one non-native cysteine |
WO2007022964A2 (de) | 2005-08-24 | 2007-03-01 | Abbott Gmbh & Co. Kg | Hetaryl substituierte guanidinverbindungen und ihre verwendung als bindungspartner für 5-ht5-rezeptoren |
TW200908984A (en) | 2007-08-07 | 2009-03-01 | Piramal Life Sciences Ltd | Pyridyl derivatives, their preparation and use |
NZ602832A (en) | 2008-07-14 | 2014-04-30 | Gilead Sciences Inc | Fused heterocyclic hdac inhibitor compounds |
JP5640005B2 (ja) | 2008-07-14 | 2014-12-10 | ギリアード サイエンシーズ, インコーポレイテッド | Hdacおよび/またはcdk阻害剤としてのイミダゾシルピリジン化合物 |
US8344018B2 (en) | 2008-07-14 | 2013-01-01 | Gilead Sciences, Inc. | Oxindolyl inhibitor compounds |
NZ590747A (en) | 2008-07-28 | 2012-11-30 | Gilead Sciences Inc | Cycloalkylidene and heterocycloalkylidene hdac inhibitor compounds |
NZ596863A (en) | 2009-06-08 | 2014-02-28 | Gilead Sciences Inc | Alkanoylamino benzamide aniline hdac inhibitor compounds |
BRPI1010883A2 (pt) | 2009-06-08 | 2018-07-10 | Gilead Sciences Inc | compostos inibidores da anilina cicloalquilcarbamato benzamida hdac. |
JP2011057661A (ja) * | 2009-08-14 | 2011-03-24 | Bayer Cropscience Ag | 殺虫性カルボキサミド類 |
US9944734B2 (en) | 2013-12-20 | 2018-04-17 | Saudi Basic Industries Corporation | Catalyst system for polymerization of an olefin |
US10774064B2 (en) | 2016-06-02 | 2020-09-15 | Cadent Therapeutics, Inc. | Potassium channel modulators |
ES2906078T3 (es) | 2017-01-23 | 2022-04-13 | Cadent Therapeutics Inc | Moduladores del canal de potasio |
BR112021007552A2 (pt) | 2018-10-22 | 2021-07-27 | Cadent Therapeutics, Inc. | formas cristalinas de moduladores de canal de potássio |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5506134A (en) | 1990-10-22 | 1996-04-09 | Corvas International, Inc. | Hypridoma and monoclonal antibody which inhibits blood coagulation tissue factor/factor VIIa complex |
US5833982A (en) | 1991-02-28 | 1998-11-10 | Zymogenetics, Inc. | Modified factor VII |
US5788965A (en) | 1991-02-28 | 1998-08-04 | Novo Nordisk A/S | Modified factor VII |
US5314902A (en) * | 1993-01-27 | 1994-05-24 | Monsanto Company | Urea derivatives useful as platelet aggregation inhibitors |
DE4309867A1 (de) * | 1993-03-26 | 1994-09-29 | Cassella Ag | Neue Harnstoffderivate, ihre Herstellung und Verwendung |
EP0987274A1 (en) * | 1998-09-15 | 2000-03-22 | Hoechst Marion Roussel Deutschland GmbH | Factor VIIa Inhibitors |
-
2001
- 2001-06-26 EP EP01115353A patent/EP1270551A1/en not_active Withdrawn
-
2002
- 2002-06-12 JP JP2003508707A patent/JP4231403B2/ja not_active Expired - Fee Related
- 2002-06-12 PT PT02758230T patent/PT1423357E/pt unknown
- 2002-06-12 AU AU2002325238A patent/AU2002325238A1/en not_active Abandoned
- 2002-06-12 DE DE60214569T patent/DE60214569T2/de not_active Expired - Lifetime
- 2002-06-12 CA CA2451206A patent/CA2451206C/en not_active Expired - Fee Related
- 2002-06-12 DK DK02758230T patent/DK1423357T3/da active
- 2002-06-12 AT AT02758230T patent/ATE338746T1/de active
- 2002-06-12 MX MXPA03011022A patent/MXPA03011022A/es active IP Right Grant
- 2002-06-12 ES ES02758230T patent/ES2269750T3/es not_active Expired - Lifetime
- 2002-06-12 EP EP02758230A patent/EP1423357B1/en not_active Expired - Lifetime
- 2002-06-12 WO PCT/EP2002/006422 patent/WO2003002524A2/en active IP Right Grant
- 2002-06-26 PE PE2002000570A patent/PE20030133A1/es not_active Application Discontinuation
- 2002-06-26 US US10/183,848 patent/US6706715B2/en not_active Expired - Lifetime
-
2006
- 2006-11-02 CY CY20061101577T patent/CY1105751T1/el unknown
Also Published As
Publication number | Publication date |
---|---|
PT1423357E (pt) | 2006-12-29 |
EP1270551A1 (en) | 2003-01-02 |
PE20030133A1 (es) | 2003-04-08 |
WO2003002524A3 (en) | 2004-03-11 |
AU2002325238A1 (en) | 2003-03-03 |
CA2451206C (en) | 2011-02-01 |
CY1105751T1 (el) | 2010-12-22 |
EP1423357B1 (en) | 2006-09-06 |
US6706715B2 (en) | 2004-03-16 |
US20030176439A1 (en) | 2003-09-18 |
CA2451206A1 (en) | 2003-01-09 |
JP4231403B2 (ja) | 2009-02-25 |
DE60214569D1 (de) | 2006-10-19 |
ES2269750T3 (es) | 2007-04-01 |
JP2004530726A (ja) | 2004-10-07 |
ATE338746T1 (de) | 2006-09-15 |
DE60214569T2 (de) | 2007-05-03 |
WO2003002524A2 (en) | 2003-01-09 |
EP1423357A2 (en) | 2004-06-02 |
MXPA03011022A (es) | 2004-03-19 |
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