DK1419240T3 - Fremstilling og anvendelse af humane CD124- og CD116-positive tumorcellelinier til fremstilling af allogene eller semi-allogene immumterapeutika - Google Patents

Fremstilling og anvendelse af humane CD124- og CD116-positive tumorcellelinier til fremstilling af allogene eller semi-allogene immumterapeutika

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Publication number
DK1419240T3
DK1419240T3 DK02758474.7T DK02758474T DK1419240T3 DK 1419240 T3 DK1419240 T3 DK 1419240T3 DK 02758474 T DK02758474 T DK 02758474T DK 1419240 T3 DK1419240 T3 DK 1419240T3
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DK
Denmark
Prior art keywords
preparation
allogeneic
cell lines
immunotherapy
semi
Prior art date
Application number
DK02758474.7T
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English (en)
Other versions
DK1419240T4 (da
Inventor
Steffen Goletz
Rik J Scheper
Alan Masterson
Herbert M Pinedo
Original Assignee
Glycotope Gmbh
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Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=7695095&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK1419240(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Glycotope Gmbh filed Critical Glycotope Gmbh
Application granted granted Critical
Publication of DK1419240T3 publication Critical patent/DK1419240T3/da
Publication of DK1419240T4 publication Critical patent/DK1419240T4/da

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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0693—Tumour cells; Cancer cells
    • C12N5/0694—Cells of blood, e.g. leukemia cells, myeloma cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0005—Vertebrate antigens
    • A61K39/0011—Cancer antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0005—Vertebrate antigens
    • A61K39/0011—Cancer antigens
    • A61K39/001169—Tumor associated carbohydrates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/46—Cellular immunotherapy
    • A61K39/461—Cellular immunotherapy characterised by the cell type used
    • A61K39/4615—Dendritic cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/46—Cellular immunotherapy
    • A61K39/462—Cellular immunotherapy characterized by the effect or the function of the cells
    • A61K39/4622—Antigen presenting cells
    • A—HUMAN NECESSITIES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K39/46—Cellular immunotherapy
    • A61K39/464—Cellular immunotherapy characterised by the antigen targeted or presented
    • A61K39/4643—Vertebrate antigens
    • A61K39/4644—Cancer antigens
    • A61K39/46448—Cancer antigens from embryonic or fetal origin
    • A61K39/464482—Carcinoembryonic antigen [CEA]
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K39/4643—Vertebrate antigens
    • A61K39/4644—Cancer antigens
    • A61K39/46449—Melanoma antigens
    • A61K39/464491—Melan-A/MART
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    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/46—Cellular immunotherapy
    • A61K39/464—Cellular immunotherapy characterised by the antigen targeted or presented
    • A61K39/4643—Vertebrate antigens
    • A61K39/4644—Cancer antigens
    • A61K39/464499—Undefined tumor antigens, e.g. tumor lysate or antigens targeted by cells isolated from tumor
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    • A61K39/4648—Bacterial antigens
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    • C12N5/0602—Vertebrate cells
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    • A61K2039/515—Animal cells
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/20—Cytokines; Chemokines
    • C12N2501/24—Interferons [IFN]
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
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  • Virology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DK02758474.7T 2001-08-17 2002-08-19 : Fremstilling og anvendelse af humane CD124- og CD116-positive tumorcellelinier til fremstilling af allogene eller semi-allogene DK1419240T4 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10139428A DE10139428A1 (de) 2001-08-17 2001-08-17 Herstellung und Verwendung von humanen CD124 und CD116 positiven Tumorzelllinien zur Herstellung von allogenen oder semi-allogenen Immuntherapeutika
PCT/EP2002/009260 WO2003023023A1 (de) 2001-08-17 2002-08-19 Herstellung und verwendung von humanen cd124 und cd116 positiven tumorzelllinien zur herstellung von allogenen oder semi-allogenen immuntherapeutika

Publications (2)

Publication Number Publication Date
DK1419240T3 true DK1419240T3 (da) 2011-10-17
DK1419240T4 DK1419240T4 (da) 2018-10-29

Family

ID=7695095

Family Applications (1)

Application Number Title Priority Date Filing Date
DK02758474.7T DK1419240T4 (da) 2001-08-17 2002-08-19 : Fremstilling og anvendelse af humane CD124- og CD116-positive tumorcellelinier til fremstilling af allogene eller semi-allogene

Country Status (8)

Country Link
US (2) US8455253B2 (da)
EP (2) EP2361973A3 (da)
AT (1) ATE513900T1 (da)
CA (1) CA2457287C (da)
DE (1) DE10139428A1 (da)
DK (1) DK1419240T4 (da)
ES (1) ES2371021T5 (da)
WO (1) WO2003023023A1 (da)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10139428A1 (de) 2001-08-17 2003-03-27 Nemod Immuntherapie Ag Herstellung und Verwendung von humanen CD124 und CD116 positiven Tumorzelllinien zur Herstellung von allogenen oder semi-allogenen Immuntherapeutika
AU2003260426A1 (en) 2002-08-16 2004-03-11 Glycotope Gmbh Process for the production of temperature-induced tumor cell lysates for use as immunogenic compounds
EP1654353B1 (en) 2003-08-18 2013-05-22 Glycotope GmbH Tumour cell lines nm-f9 (dsm acc2606) and nm-d4 (dsm acc2605), uses threreof
ES2620261T3 (es) 2006-09-10 2017-06-28 Glycotope Gmbh Uso de células humanas de origen leucémico mieloide para expresión de anticuerpos
PL1920781T3 (pl) * 2006-11-10 2015-06-30 Glycotope Gmbh Kompozycje zawierające core-1-dodatnie mikroorganizmy i ich zastosowanie w leczeniu lub profilaktyce nowotworów
FR2931163B1 (fr) * 2008-05-16 2013-01-18 Ets Francais Du Sang Lignee de cellules dendritiques plasmacytoides utilisee en therapie cellulaire active ou adoptive
CN103814123A (zh) 2011-08-22 2014-05-21 葛莱高托普有限公司 携带肿瘤抗原的微生物
NL2009102C2 (en) * 2012-07-02 2014-01-06 Dcprime B V Method for dc-loading.
EP2743344A1 (en) * 2012-12-11 2014-06-18 DCPrime B.V. Therapeutic cancer vaccines derived from a novel dendritic cell line
WO2018096078A1 (en) 2016-11-25 2018-05-31 Glycotope Gmbh Serum-free cultivation of progenitor dendritic cells
US20190076473A1 (en) * 2017-09-14 2019-03-14 Cellular Approaches, Inc. Autologous and allogenic macrophages and monocytes for use in therapeutic methods
DK3794042T3 (da) 2018-05-18 2024-04-15 Daiichi Sankyo Co Ltd Anti-muc1-exatecet-antistof-lægemiddelkonjugat

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6300090B1 (en) * 1994-07-29 2001-10-09 The Rockefeller University Methods of use of viral vectors to deliver antigen to dendritic cells
US5648219A (en) * 1995-06-07 1997-07-15 Zymogenetics, Inc. Immortalized dendritic cells
AU2326297A (en) * 1996-03-06 1997-09-22 I. Belloch Corporation Method for treating liquid materials
US5811297A (en) * 1996-03-07 1998-09-22 Amba Biosciences, Llc Immortalized hematopoietic cell lines, cell system thereof with stromal cells, in vitro, ex vivo and in vivo uses, & in vitro generation of dendritic cells and macrophages
JP2002501377A (ja) * 1997-04-15 2002-01-15 ダナ−ファーバー キャンサー インスティテュート インク． 樹状細胞ハイブリッド
US20020041868A1 (en) * 1997-04-15 2002-04-11 Charles Nicolette Cell fusions and methods of making and using the same
US20020090381A1 (en) * 1999-04-09 2002-07-11 H. Kim Bottomly System for controlling immune system response to antigen
DE10019075B4 (de) * 2000-04-18 2007-01-18 Vision 7 Gmbh Verwendung von CD34 oder einem davon abgeleiteten Polypeptid als Zell-Oberflächen- bzw. Gentransfer-Marker
DE10139428A1 (de) 2001-08-17 2003-03-27 Nemod Immuntherapie Ag Herstellung und Verwendung von humanen CD124 und CD116 positiven Tumorzelllinien zur Herstellung von allogenen oder semi-allogenen Immuntherapeutika

Also Published As

Publication number Publication date
CA2457287A1 (en) 2003-03-20
EP2361973A3 (de) 2012-08-15
DE10139428A1 (de) 2003-03-27
EP1419240B1 (de) 2011-06-22
EP1419240A1 (de) 2004-05-19
WO2003023023A1 (de) 2003-03-20
CA2457287C (en) 2016-01-19
US8455253B2 (en) 2013-06-04
DK1419240T4 (da) 2018-10-29
ATE513900T1 (de) 2011-07-15
US20040265998A1 (en) 2004-12-30
EP1419240B2 (de) 2018-07-11
WO2003023023B1 (de) 2003-11-27
ES2371021T3 (es) 2011-12-26
US9029143B2 (en) 2015-05-12
US20120308607A1 (en) 2012-12-06
ES2371021T5 (es) 2018-11-20
EP2361973A2 (de) 2011-08-31

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