DK140491A - Pattedyrs-somatotropin, dets anvendelse til foroegelse af dyrs vaekst og af droevtyggeres maelkeproduktion samt vektor indeholdende dna, der koder for et pattedyrs-somatropin, og en mikroorganisme, der er vaert for en saadan vektor - Google Patents

Pattedyrs-somatotropin, dets anvendelse til foroegelse af dyrs vaekst og af droevtyggeres maelkeproduktion samt vektor indeholdende dna, der koder for et pattedyrs-somatropin, og en mikroorganisme, der er vaert for en saadan vektor Download PDF

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Publication number
DK140491A
DK140491A DK140491A DK140491A DK140491A DK 140491 A DK140491 A DK 140491A DK 140491 A DK140491 A DK 140491A DK 140491 A DK140491 A DK 140491A DK 140491 A DK140491 A DK 140491A
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DK
Denmark
Prior art keywords
pattern
ordanic
micropane
laborators
somatropin
Prior art date
Application number
DK140491A
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Danish (da)
English (en)
Other versions
DK140491D0 (da
Inventor
Alan J Parcells
John E Mott
Che-Shen C Tomich
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Upjohn Co filed Critical Upjohn Co
Publication of DK140491D0 publication Critical patent/DK140491D0/da
Publication of DK140491A publication Critical patent/DK140491A/da

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • C07K14/61Growth hormone [GH], i.e. somatotropin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Endocrinology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Cosmetics (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DK140491A 1989-01-31 1991-07-29 Pattedyrs-somatotropin, dets anvendelse til foroegelse af dyrs vaekst og af droevtyggeres maelkeproduktion samt vektor indeholdende dna, der koder for et pattedyrs-somatropin, og en mikroorganisme, der er vaert for en saadan vektor DK140491A (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US30473389A 1989-01-31 1989-01-31
PCT/US1989/005445 WO1990008823A1 (en) 1989-01-31 1989-12-11 Somatotropin analogs

Publications (2)

Publication Number Publication Date
DK140491D0 DK140491D0 (da) 1991-07-29
DK140491A true DK140491A (da) 1991-07-29

Family

ID=23177749

Family Applications (1)

Application Number Title Priority Date Filing Date
DK140491A DK140491A (da) 1989-01-31 1991-07-29 Pattedyrs-somatotropin, dets anvendelse til foroegelse af dyrs vaekst og af droevtyggeres maelkeproduktion samt vektor indeholdende dna, der koder for et pattedyrs-somatropin, og en mikroorganisme, der er vaert for en saadan vektor

Country Status (6)

Country Link
EP (1) EP0456642A1 (ja)
JP (1) JP3207416B2 (ja)
AU (1) AU620673B2 (ja)
CA (1) CA2005502C (ja)
DK (1) DK140491A (ja)
WO (1) WO1990008823A1 (ja)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE198353T1 (de) * 1988-08-24 2001-01-15 American Cyanamid Co Stabilisierung von somatotropinen durch modifikation von cystein-resten durch orts- spezifische mutagenese oder chemische derivatisierung
US5688666A (en) * 1988-10-28 1997-11-18 Genentech, Inc. Growth hormone variants with altered binding properties
US5534617A (en) * 1988-10-28 1996-07-09 Genentech, Inc. Human growth hormone variants having greater affinity for human growth hormone receptor at site 1
US5849694A (en) * 1990-07-16 1998-12-15 Synenki; Richard M. Stable and bioactive modified porcine somatotropin and pharmaceutical compositions thereof
CA2658039A1 (en) * 1995-09-21 1997-03-27 Genentech, Inc. Human growth hormone variants
US7173003B2 (en) 2001-10-10 2007-02-06 Neose Technologies, Inc. Granulocyte colony stimulating factor: remodeling and glycoconjugation of G-CSF
US7214660B2 (en) 2001-10-10 2007-05-08 Neose Technologies, Inc. Erythropoietin: remodeling and glycoconjugation of erythropoietin
US7795210B2 (en) 2001-10-10 2010-09-14 Novo Nordisk A/S Protein remodeling methods and proteins/peptides produced by the methods
US8008252B2 (en) 2001-10-10 2011-08-30 Novo Nordisk A/S Factor VII: remodeling and glycoconjugation of Factor VII
US7696163B2 (en) 2001-10-10 2010-04-13 Novo Nordisk A/S Erythropoietin: remodeling and glycoconjugation of erythropoietin
NZ542094A (en) 2003-03-14 2008-12-24 Neose Technologies Inc Branched polymer conjugates comprising a peptide and water-soluble polymer chains
MXPA05010773A (es) 2003-04-09 2005-12-12 Neose Technologies Inc Metodos de glicopegilacion y proteinas/peptidos producidos por los metodos.
AU2004240553A1 (en) * 2003-05-09 2004-12-02 Neose Technologies, Inc. Compositions and methods for the preparation of human growth hormone glycosylation mutants
WO2005012484A2 (en) 2003-07-25 2005-02-10 Neose Technologies, Inc. Antibody-toxin conjugates
US8633157B2 (en) 2003-11-24 2014-01-21 Novo Nordisk A/S Glycopegylated erythropoietin
US20080305992A1 (en) 2003-11-24 2008-12-11 Neose Technologies, Inc. Glycopegylated erythropoietin
US7956032B2 (en) 2003-12-03 2011-06-07 Novo Nordisk A/S Glycopegylated granulocyte colony stimulating factor
ES2560657T3 (es) 2004-01-08 2016-02-22 Ratiopharm Gmbh Glicosilación con unión en O de péptidos G-CSF
US20080300173A1 (en) 2004-07-13 2008-12-04 Defrees Shawn Branched Peg Remodeling and Glycosylation of Glucagon-Like Peptides-1 [Glp-1]
US8268967B2 (en) 2004-09-10 2012-09-18 Novo Nordisk A/S Glycopegylated interferon α
EP1814573B1 (en) 2004-10-29 2016-03-09 ratiopharm GmbH Remodeling and glycopegylation of fibroblast growth factor (fgf)
ES2449195T3 (es) 2005-01-10 2014-03-18 Ratiopharm Gmbh Factor estimulante de colonias de granulocitos glicopegilado
WO2006121569A2 (en) 2005-04-08 2006-11-16 Neose Technologies, Inc. Compositions and methods for the preparation of protease resistant human growth hormone glycosylation mutants
EP1888098A2 (en) 2005-05-25 2008-02-20 Neose Technologies, Inc. Glycopegylated erythropoietin formulations
US20070105755A1 (en) 2005-10-26 2007-05-10 Neose Technologies, Inc. One pot desialylation and glycopegylation of therapeutic peptides
WO2007056191A2 (en) 2005-11-03 2007-05-18 Neose Technologies, Inc. Nucleotide sugar purification using membranes
WO2008011633A2 (en) 2006-07-21 2008-01-24 Neose Technologies, Inc. Glycosylation of peptides via o-linked glycosylation sequences
US8969532B2 (en) 2006-10-03 2015-03-03 Novo Nordisk A/S Methods for the purification of polypeptide conjugates comprising polyalkylene oxide using hydrophobic interaction chromatography
CN101796063B (zh) 2007-04-03 2017-03-22 拉蒂奥法姆有限责任公司 使用糖聚乙二醇化g‑csf的治疗方法
ES2551123T3 (es) 2007-06-12 2015-11-16 Ratiopharm Gmbh Proceso mejorado para la producción de azúcares de nucleótido
US8207112B2 (en) 2007-08-29 2012-06-26 Biogenerix Ag Liquid formulation of G-CSF conjugate
JP5619630B2 (ja) 2008-02-27 2014-11-05 ノボ・ノルデイスク・エー/エス 結合型第viii因子分子

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE56026B1 (en) * 1982-10-19 1991-03-27 Cetus Corp Cysteine-depleted muteins of biologically active proteins

Also Published As

Publication number Publication date
EP0456642A1 (en) 1991-11-21
JPH04503001A (ja) 1992-06-04
DK140491D0 (da) 1991-07-29
CA2005502C (en) 2001-06-05
CA2005502A1 (en) 1990-07-31
AU4663189A (en) 1990-08-24
JP3207416B2 (ja) 2001-09-10
AU620673B2 (en) 1992-02-20
WO1990008823A1 (en) 1990-08-09

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