DK139576B - Fremgangsmåde til isolering af alfa-6-desoxy-5-oxytetracyklin. - Google Patents

Fremgangsmåde til isolering af alfa-6-desoxy-5-oxytetracyklin.

Info

Publication number
DK139576B
DK139576B DK166871AA DK166871A DK139576B DK 139576 B DK139576 B DK 139576B DK 166871A A DK166871A A DK 166871AA DK 166871 A DK166871 A DK 166871A DK 139576 B DK139576 B DK 139576B
Authority
DK
Denmark
Prior art keywords
oxytetracycline
deoxy
alpha
isolation
Prior art date
Application number
DK166871AA
Other languages
Danish (da)
English (en)
Other versions
DK139576C (xx
Inventor
Franco Paolo Luciano
Original Assignee
Rachelle Labor Italia Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rachelle Labor Italia Spa filed Critical Rachelle Labor Italia Spa
Publication of DK139576B publication Critical patent/DK139576B/da
Application granted granted Critical
Publication of DK139576C publication Critical patent/DK139576C/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/24Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a ring other than a six-membered aromatic ring of the carbon skeleton
    • C07C237/26Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a ring other than a six-membered aromatic ring of the carbon skeleton of a ring being part of a condensed ring system formed by at least four rings, e.g. tetracycline
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/65Tetracyclines
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00Preparation of carboxylic acid amides
    • C07C231/12Preparation of carboxylic acid amides by reactions not involving the formation of carboxamide groups
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2231/00Catalytic reactions performed with catalysts classified in B01J31/00
    • B01J2231/60Reduction reactions, e.g. hydrogenation
    • B01J2231/64Reductions in general of organic substrates, e.g. hydride reductions or hydrogenations
    • B01J2231/641Hydrogenation of organic substrates, i.e. H2 or H-transfer hydrogenations, e.g. Fischer-Tropsch processes
    • B01J2231/645Hydrogenation of organic substrates, i.e. H2 or H-transfer hydrogenations, e.g. Fischer-Tropsch processes of C=C or C-C triple bonds
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2603/00Systems containing at least three condensed rings
    • C07C2603/02Ortho- or ortho- and peri-condensed systems
    • C07C2603/40Ortho- or ortho- and peri-condensed systems containing four condensed rings
    • C07C2603/42Ortho- or ortho- and peri-condensed systems containing four condensed rings containing only six-membered rings
    • C07C2603/44Naphthacenes; Hydrogenated naphthacenes
    • C07C2603/461,4,4a,5,5a,6,11,12a- Octahydronaphthacenes, e.g. tetracyclines

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK166871AA 1970-12-28 1971-04-07 Fremgangsmåde til isolering af alfa-6-desoxy-5-oxytetracyklin. DK139576B (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US10209470A 1970-12-28 1970-12-28

Publications (2)

Publication Number Publication Date
DK139576B true DK139576B (da) 1979-03-12
DK139576C DK139576C (xx) 1979-08-27

Family

ID=22288092

Family Applications (1)

Application Number Title Priority Date Filing Date
DK166871AA DK139576B (da) 1970-12-28 1971-04-07 Fremgangsmåde til isolering af alfa-6-desoxy-5-oxytetracyklin.

Country Status (17)

Country Link
US (1) US3795707A (xx)
JP (1) JPS535299B1 (xx)
BE (1) BE777357A (xx)
CA (1) CA972745A (xx)
CH (1) CH567456A5 (xx)
DE (1) DE2117442B2 (xx)
DK (1) DK139576B (xx)
ES (1) ES391290A1 (xx)
FI (1) FI53302B (xx)
FR (1) FR2120866A5 (xx)
GB (1) GB1370797A (xx)
IE (1) IE35673B1 (xx)
IL (1) IL37883A (xx)
NL (1) NL7113277A (xx)
NO (1) NO133102C (xx)
SE (1) SE373836B (xx)
ZA (1) ZA716574B (xx)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3906043A (en) * 1969-06-12 1975-09-16 Israel Marcus Water-soluble tetracyclines
US4061676A (en) * 1970-07-03 1977-12-06 Ivan Villax Recovery of doxycycline and products thereof
DK386784A (da) * 1983-08-17 1985-02-18 Hovione Int Ltd Fremgangsmaade til fremstilling af alfa-6-desoxy-tetracykliner
US5371076A (en) * 1993-04-02 1994-12-06 American Cyanamid Company 9-[(substituted glycyl)amido]-6-(substituted)-5-hydroxy-6-deoxytetracyclines
US20020132798A1 (en) * 2000-06-16 2002-09-19 Nelson Mark L. 7-phenyl-substituted tetracycline compounds
EP2311799A1 (en) * 2002-01-08 2011-04-20 Paratek Pharmaceuticals, Inc. 4-dedimethylamino tetracycline compounds
IL164180A0 (en) 2002-03-21 2005-12-18 Paratek Pharm Innc Substituted tetracycline compounds
US20060287283A1 (en) * 2003-07-09 2006-12-21 Paratek Pharmaceuticals, Inc. Prodrugs of 9-aminomethyl tetracycline compounds
EA201100956A1 (ru) 2003-07-09 2012-01-30 Пэрэтек Фамэсьютикэлс, Инк. Замещенные соединения тетрациклина (варианты), фармацевтическая композиция и способ лечения чувствительного к тетрациклину состояния у субъекта

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH365484A (fr) * 1956-05-28 1962-11-15 American Cyanamid Co Procédé de préparation d'une substance antibiotique
FR1430859A (xx) * 1960-05-23 1966-05-25
US3397231A (en) * 1967-04-12 1968-08-13 Pfizer & Co C Refining of alpha-6-deoxy-5-oxytetracycline
CA945546A (en) * 1970-07-03 1974-04-16 Ivan Villax Recovery of doxycycline and products thereof

Also Published As

Publication number Publication date
IE35673L (en) 1972-06-28
CA972745A (en) 1975-08-12
GB1370797A (en) 1974-10-16
DE2117442B2 (de) 1980-06-04
CH567456A5 (xx) 1975-10-15
JPS535299B1 (xx) 1978-02-25
BE777357A (fr) 1972-04-17
NO133102C (xx) 1976-03-10
IE35673B1 (en) 1976-04-14
IL37883A (en) 1974-12-31
ZA716574B (en) 1973-05-30
IL37883A0 (en) 1971-12-29
FI53302B (xx) 1977-12-30
SE373836B (xx) 1975-02-17
ES391290A1 (es) 1972-01-16
DE2117442A1 (de) 1972-07-27
DK139576C (xx) 1979-08-27
NO133102B (xx) 1975-12-01
FR2120866A5 (xx) 1972-08-18
US3795707A (en) 1974-03-05
NL7113277A (xx) 1972-06-30

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