DK1368348T3 - Hidtil ukendte 2,5-diazabicyclo[2.2.1]heptanderivater - Google Patents

Hidtil ukendte 2,5-diazabicyclo[2.2.1]heptanderivater

Info

Publication number
DK1368348T3
DK1368348T3 DK02700189T DK02700189T DK1368348T3 DK 1368348 T3 DK1368348 T3 DK 1368348T3 DK 02700189 T DK02700189 T DK 02700189T DK 02700189 T DK02700189 T DK 02700189T DK 1368348 T3 DK1368348 T3 DK 1368348T3
Authority
DK
Denmark
Prior art keywords
diseases
disorders
diazabicyclo
heptane derivatives
nervous system
Prior art date
Application number
DK02700189T
Other languages
Danish (da)
English (en)
Inventor
Gunnar M Olsen
Dan Peters
Elsebet Nielsen
Philip K Ahring
Tino Joergensen
Original Assignee
Neurosearch As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Neurosearch As filed Critical Neurosearch As
Application granted granted Critical
Publication of DK1368348T3 publication Critical patent/DK1368348T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/08—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4995—Pyrazines or piperazines forming part of bridged ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Psychiatry (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Diabetes (AREA)
  • Child & Adolescent Psychology (AREA)
  • Psychology (AREA)
  • Anesthesiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DK02700189T 2001-03-02 2002-02-28 Hidtil ukendte 2,5-diazabicyclo[2.2.1]heptanderivater DK1368348T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DKPA200100344 2001-03-02
PCT/DK2002/000133 WO2002070522A1 (en) 2001-03-02 2002-02-28 Novel 2,5-diazabicyclo[2.2.1]heptane derivatives

Publications (1)

Publication Number Publication Date
DK1368348T3 true DK1368348T3 (da) 2005-05-23

Family

ID=8160337

Family Applications (1)

Application Number Title Priority Date Filing Date
DK02700189T DK1368348T3 (da) 2001-03-02 2002-02-28 Hidtil ukendte 2,5-diazabicyclo[2.2.1]heptanderivater

Country Status (13)

Country Link
US (1) US7329754B2 (ja)
EP (1) EP1368348B1 (ja)
JP (1) JP4294958B2 (ja)
CN (1) CN1331864C (ja)
AT (1) ATE287404T1 (ja)
AU (1) AU2002233181B2 (ja)
CA (1) CA2438815A1 (ja)
DE (1) DE60202667T2 (ja)
DK (1) DK1368348T3 (ja)
HK (1) HK1068878A1 (ja)
MX (1) MXPA03007895A (ja)
NZ (1) NZ527006A (ja)
WO (1) WO2002070522A1 (ja)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2468015A1 (en) * 2001-11-27 2003-06-05 Merck & Co., Inc. 2-aminoquinoline compounds
BRPI0908807A2 (pt) * 2008-02-15 2015-07-28 Hoffmann La Roche Derivados de 3-alquil-piperazina e usos dos mesmos

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IN166416B (ja) * 1985-09-18 1990-05-05 Pfizer
US5196548A (en) 1989-05-11 1993-03-23 Pfizer Inc. Preparation of diazabicyclic Intermediates
JPH06228138A (ja) 1993-02-03 1994-08-16 Fujisawa Pharmaceut Co Ltd ピリドシンノリン化合物またはその塩及びこれを含有する抗菌剤
US5478939A (en) * 1994-07-20 1995-12-26 American Cyanamid Company (R,R) and (S,S) 2,5-diazabicyclo [2,2,1]heptane derivatives
US5561127A (en) 1994-12-19 1996-10-01 Allelix Biopharmaceuticals, Inc. Muscarinic receptor ligands
FR2786769B1 (fr) 1998-12-04 2002-10-25 Synthelabo Derives de 2,5-diazabicyclo[2.2.1]heptane, leur preparation et leur application en therapeutique
EP1147112B1 (en) * 1999-01-29 2003-10-29 Abbott Laboratories Diazabicyclic derivatives as nicotinic acetylcholine receptor ligands
PT1289996E (pt) 2000-05-25 2005-07-29 Targacept Inc Heteroarildiazabicicloalcanos como ligandos do receptor colinergico nicotinico
CA2354606C (en) 2000-08-03 2005-12-06 Pfizer Products Inc. Azabicycloalkane derivatives and therapeutic uses thereof

Also Published As

Publication number Publication date
CA2438815A1 (en) 2002-09-12
EP1368348B1 (en) 2005-01-19
HK1068878A1 (en) 2005-05-06
US7329754B2 (en) 2008-02-12
EP1368348A1 (en) 2003-12-10
JP2004529901A (ja) 2004-09-30
NZ527006A (en) 2005-02-25
ATE287404T1 (de) 2005-02-15
US20040181069A1 (en) 2004-09-16
CN1331864C (zh) 2007-08-15
MXPA03007895A (es) 2003-12-04
AU2002233181B2 (en) 2007-06-07
CN1535273A (zh) 2004-10-06
JP4294958B2 (ja) 2009-07-15
DE60202667D1 (de) 2005-02-24
DE60202667T2 (de) 2005-06-16
WO2002070522A1 (en) 2002-09-12

Similar Documents

Publication Publication Date Title
IS7742A (is) Nýjar kvínúklidín-afleiður og notkun þeirra
HK1068628A1 (en) Nicotinic acetyl-choline receptors inhibitor compounds, their preparation and use
DK1551835T3 (da) Hidtil ukendte 1,4-diazabicycloalkanderivater, deres fremstilling og anvendelse
ATE385497T1 (de) 3-substituierte quinuclidin-derivate und deren verwendung als nikotinischen agonisten
DK1506200T3 (da) Diazabicykliske biarylderivater
AU6583101A (en) Aryl and heteroaryl diazabicycloalkanes, their preparation and use
DK1562945T3 (da) Hidtil ukendte diazebicykliske biarylderivater
ATE289310T1 (de) Heteroaryl-diazabicycloalkanderivaten als cns- modulatoren
ATE289607T1 (de) Neue heteroaryl-diazabizykloalkane
HK1079528A1 (en) Azacyclic ethynyl derivatives
ATE445618T1 (de) Neue diazabicyclische arylderivate
DE60307102D1 (de) 3-substituierte chinuklidine und deren verwendung
HK1068878A1 (en) Novel 2, 5-diazabicyclo Ä2.2.1Üheptane derivatives
DE602004031124D1 (de) Neue chinuklidinderivative und deren pharmazeutische verwendung