DK136719B - Analogifremgangsmåde til fremstilling af substituerede hexahydro-dibenzo(b,d)-pyraner. - Google Patents

Analogifremgangsmåde til fremstilling af substituerede hexahydro-dibenzo(b,d)-pyraner.

Info

Publication number
DK136719B
DK136719B DK573274AA DK573274A DK136719B DK 136719 B DK136719 B DK 136719B DK 573274A A DK573274A A DK 573274AA DK 573274 A DK573274 A DK 573274A DK 136719 B DK136719 B DK 136719B
Authority
DK
Denmark
Prior art keywords
pyrans
dibenzo
preparation
analogous process
substituted hexahydro
Prior art date
Application number
DK573274AA
Other languages
Danish (da)
English (en)
Other versions
DK573274A (ro
DK136719C (ro
Inventor
Robert Allen Archer
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of DK573274A publication Critical patent/DK573274A/da
Publication of DK136719B publication Critical patent/DK136719B/da
Application granted granted Critical
Publication of DK136719C publication Critical patent/DK136719C/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D311/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/78Ring systems having three or more relevant rings
    • C07D311/80Dibenzopyrans; Hydrogenated dibenzopyrans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/26Psychostimulants, e.g. nicotine, cocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Anesthesiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrane Compounds (AREA)
DK573274AA 1973-11-05 1974-11-04 Analogifremgangsmåde til fremstilling af substituerede hexahydro-dibenzo(b,d)-pyraner. DK136719B (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/413,010 US3968125A (en) 1973-11-05 1973-11-05 Dihydroxyhexahydrodibenzo[b,d]pyrans

Publications (3)

Publication Number Publication Date
DK573274A DK573274A (ro) 1975-07-07
DK136719B true DK136719B (da) 1977-11-14
DK136719C DK136719C (ro) 1978-04-24

Family

ID=23635420

Family Applications (1)

Application Number Title Priority Date Filing Date
DK573274AA DK136719B (da) 1973-11-05 1974-11-04 Analogifremgangsmåde til fremstilling af substituerede hexahydro-dibenzo(b,d)-pyraner.

Country Status (26)

Country Link
US (1) US3968125A (ro)
JP (1) JPS6033835B2 (ro)
AR (1) AR202318A1 (ro)
AT (1) AT336012B (ro)
BE (1) BE821716A (ro)
BG (1) BG26387A3 (ro)
CA (1) CA1023753A (ro)
CH (1) CH605894A5 (ro)
CS (1) CS193507B2 (ro)
DD (1) DD116230A5 (ro)
DE (1) DE2451934C2 (ro)
DK (1) DK136719B (ro)
ES (1) ES431674A1 (ro)
FR (1) FR2249664B1 (ro)
GB (1) GB1487637A (ro)
HU (1) HU169193B (ro)
IE (1) IE40023B1 (ro)
IL (1) IL45644A (ro)
NL (1) NL7414439A (ro)
PH (1) PH11788A (ro)
PL (2) PL95748B1 (ro)
RO (1) RO71766A (ro)
SE (1) SE415762B (ro)
SU (1) SU524517A3 (ro)
YU (1) YU36515B (ro)
ZA (1) ZA745751B (ro)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1522057A (en) * 1975-11-03 1978-08-23 Pfizer 9-hydroxydibenzo(b,d)pyrans and intermediates therefor
US4051152A (en) * 1976-01-07 1977-09-27 Sharps Associates Oxo C-ring benzopyrans
US4087546A (en) * 1976-02-17 1978-05-02 Eli Lilly And Company Hexahydro-dibenzo[b,d]pyran-9-ones as antiasthmatic drugs
US4087545A (en) * 1976-02-17 1978-05-02 Eli Lilly And Company Hexahydro-dibenzo[b,d]pyran-9-ones as antiemetic drugs
SE7704749L (sv) * 1976-05-17 1977-12-05 Pfizer Kinoliner och forfarande och mellanprodukter for framstellning derav
US4054581A (en) * 1976-07-06 1977-10-18 Eli Lilly And Company Preparation of cis-1-hydroxy-3-substituted-6,6-dimethyl-6,6a,7,8,10,10a-hexahydro-9H-dibenzo[b,d]pyran-9-ones and intermediates therefor
US4209520A (en) * 1977-06-17 1980-06-24 Pfizer Inc. Hexahydro-1-hydroxy-9-hydroxymethyl-3-substituted-6H-dibenzo[b,d]pyrans as analgesic agents
US4133819A (en) * 1977-06-17 1979-01-09 Pfizer Inc. Hexahydro-1-hydroxy-9-hydroxymethyl-3-substituted-6H-dibenzo[b,d]pyrans as analgesic agents
US4243674A (en) * 1978-06-12 1981-01-06 Pfizer Inc. 9-Hydroxydibenzo[b,d]pyrans and intermediates therefore
US4454144A (en) * 1982-06-21 1984-06-12 Pfizer Inc. Substituted dibenzo[b,d]pyran analgesics
JPS6299930U (ro) * 1985-12-12 1987-06-25
US8449908B2 (en) * 2000-12-22 2013-05-28 Alltranz, Llc Transdermal delivery of cannabidiol
CA2450073C (en) 2001-07-25 2017-08-29 Biomarin Pharmaceutical Inc. Compositions and methods for modulating blood-brain barrier transport
JPWO2003070277A1 (ja) 2002-02-19 2005-06-09 塩野義製薬株式会社 抗掻痒剤
EP3827747A1 (en) 2005-04-28 2021-06-02 Otsuka Pharmaceutical Co., Ltd. Pharma-informatics system
EP2063905B1 (en) 2006-09-18 2014-07-30 Raptor Pharmaceutical Inc Treatment of liver disorders by administration of receptor-associated protein (rap)-conjugates
MX2010001242A (es) * 2007-07-30 2010-07-02 Alltranz Inc Profarmacos de canabidiol, composiciones que comprenden profarmacos de canabidiol y metodos para utilizar los mismos.
EP2254601B1 (en) 2008-02-08 2019-05-29 Nektar Therapeutics Oligomer-cannabinoid conjugates
US20090247619A1 (en) * 2008-03-06 2009-10-01 University Of Kentucky Cannabinoid-Containing Compositions and Methods for Their Use
HUE059078T2 (hu) 2009-02-20 2022-10-28 Enhanx Biopharm Inc Glutation-alapú hatóanyagszállító rendszer
IL295075A (en) 2009-05-06 2022-09-01 Laboratory Skin Care Inc Preparations for administration through the skin that include complexes of an active substance with calcium phosphate and methods of using them
US20120077778A1 (en) 2010-09-29 2012-03-29 Andrea Bourdelais Ladder-Frame Polyether Conjugates
CA3070156A1 (en) 2017-07-20 2019-01-24 Yissum Research Development Company Of The Hebrew University Of Jerusam Ltd. Pharmaceutical film compositions for delivery of lipophilic compounds into and/or across the skin
WO2019049145A1 (en) 2017-09-11 2019-03-14 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. COMPOSITIONS AND METHODS FOR NASAL BRAIN MEDICATION ADMINISTRATION FOR SYSTEMIC EFFECT
US20200345656A1 (en) 2017-11-29 2020-11-05 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Cannabinoids compositions and methods
WO2020089905A1 (en) 2018-11-04 2020-05-07 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Orally administrable cannabinoids-containing compositions and methods

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3507885A (en) * 1966-03-25 1970-04-21 Hoffmann La Roche 3-alkyl-6h-dibenzo(b,d)pyrans
US3636058A (en) * 1966-03-25 1972-01-18 Hoffmann La Roche 7 10 - dihydro - 3 - alkyl - 6h - dibenzo(b d) pyran-6 9(8h)-diones and 5-hydroxy-7-alkyl-4-chromanones
CH558792A (de) * 1971-10-14 1975-02-14 Petrzilka Theodor Verfahren zur herstellung von tetrahydrodibenzopyranen.

Also Published As

Publication number Publication date
CH605894A5 (ro) 1978-10-13
US3968125A (en) 1976-07-06
PL93908B1 (ro) 1977-07-30
ES431674A1 (es) 1976-11-16
DK573274A (ro) 1975-07-07
HU169193B (ro) 1976-10-28
PL95748B1 (pl) 1977-11-30
IL45644A (en) 1978-03-10
SE7413833L (ro) 1975-05-06
RO71766A (ro) 1982-12-06
AU7321274A (en) 1976-03-18
YU36515B (en) 1984-02-29
CA1023753A (en) 1978-01-03
NL7414439A (nl) 1975-05-07
BE821716A (fr) 1975-04-30
DK136719C (ro) 1978-04-24
PH11788A (en) 1978-07-05
IE40023B1 (en) 1979-02-28
CS193507B2 (en) 1979-10-31
DE2451934C2 (de) 1983-10-06
IE40023L (en) 1975-05-05
DD116230A5 (ro) 1975-11-12
IL45644A0 (en) 1974-11-29
JPS6033835B2 (ja) 1985-08-05
FR2249664B1 (ro) 1978-03-24
YU265874A (en) 1982-02-25
FR2249664A1 (ro) 1975-05-30
SU524517A3 (ru) 1976-08-05
ZA745751B (en) 1976-04-28
AT336012B (de) 1977-04-12
BG26387A3 (ro) 1979-03-15
SE415762B (sv) 1980-10-27
GB1487637A (en) 1977-10-05
ATA886374A (de) 1976-08-15
JPS5071678A (ro) 1975-06-13
DE2451934A1 (de) 1975-05-07
AR202318A1 (es) 1975-05-30

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