DK1363641T3 - Progestagen, der er co-mikroniseret med et overfladeaktivt middel, farmaceutisk præparat, som indeholder det, fremgangsmåder til fremstilling deraf samt anvendelser deraf - Google Patents
Progestagen, der er co-mikroniseret med et overfladeaktivt middel, farmaceutisk præparat, som indeholder det, fremgangsmåder til fremstilling deraf samt anvendelser derafInfo
- Publication number
- DK1363641T3 DK1363641T3 DK02708426T DK02708426T DK1363641T3 DK 1363641 T3 DK1363641 T3 DK 1363641T3 DK 02708426 T DK02708426 T DK 02708426T DK 02708426 T DK02708426 T DK 02708426T DK 1363641 T3 DK1363641 T3 DK 1363641T3
- Authority
- DK
- Denmark
- Prior art keywords
- micronized
- surfactant
- pharmaceutical composition
- methods
- progestagen
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/12—Drugs for genital or sexual disorders; Contraceptives for climacteric disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
Landscapes
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR0102814A FR2821555B1 (fr) | 2001-03-01 | 2001-03-01 | Progestatif co-micronise avec un tensioactif, composition pharmaceutique le comprenant, leurs procedes de fabrication et leurs utilisations |
Publications (1)
Publication Number | Publication Date |
---|---|
DK1363641T3 true DK1363641T3 (da) | 2006-03-13 |
Family
ID=8860623
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK02708426T DK1363641T3 (da) | 2001-03-01 | 2002-02-27 | Progestagen, der er co-mikroniseret med et overfladeaktivt middel, farmaceutisk præparat, som indeholder det, fremgangsmåder til fremstilling deraf samt anvendelser deraf |
Country Status (9)
Country | Link |
---|---|
US (2) | US7163699B2 (da) |
EP (1) | EP1363641B1 (da) |
AT (1) | ATE307593T1 (da) |
CA (1) | CA2445308A1 (da) |
DE (1) | DE60206883T2 (da) |
DK (1) | DK1363641T3 (da) |
ES (1) | ES2251577T3 (da) |
FR (1) | FR2821555B1 (da) |
WO (1) | WO2002069978A1 (da) |
Families Citing this family (33)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20020132801A1 (en) * | 2001-01-11 | 2002-09-19 | Schering Aktiengesellschaft | Drospirenone for hormone replacement therapy |
CN1299686C (zh) * | 2003-04-03 | 2007-02-14 | 上海医药工业研究院 | 黄体酮半固体骨架制剂的组合物 |
WO2006128057A2 (en) * | 2005-05-26 | 2006-11-30 | Duramed Pharmaceuticals, Inc. | Oral dosage forms comprising progesterone and methods of making and using the same |
JP2010514793A (ja) * | 2006-12-28 | 2010-05-06 | レプロス セラピューティクス インコーポレイティド | 抗プロゲスチンのバイオアベイラビリティを改善するための方法および製剤 |
EA022208B1 (ru) * | 2008-10-10 | 2015-11-30 | Тева Вимен'С Хелс, Инк. | Способы лечения вазомоторных симптомов у кастрированных пациентов с раком предстательной железы низкими дозами ципротерона ацетата |
US9795617B2 (en) * | 2009-06-18 | 2017-10-24 | Baucom Institute for Longevity and Life Enhancement, Inc. | Hormone delivery system and method |
US20140179646A1 (en) * | 2009-06-18 | 2014-06-26 | Baucom Institute for Longevity and Life Enhancement, Inc. | Hormone delivery system and method |
WO2011097571A2 (en) * | 2010-02-08 | 2011-08-11 | Prairie Pharmaceuticals, Llc | Methods for the use of progestogen as a glucocorticoid sensitizer |
US9375437B2 (en) | 2010-06-18 | 2016-06-28 | Lipocine Inc. | Progesterone containing oral dosage forms and kits |
US20110312928A1 (en) * | 2010-06-18 | 2011-12-22 | Lipocine Inc. | Progesterone Containing Oral Dosage Forms and Related Methods |
US8951996B2 (en) | 2011-07-28 | 2015-02-10 | Lipocine Inc. | 17-hydroxyprogesterone ester-containing oral compositions and related methods |
US9301920B2 (en) | 2012-06-18 | 2016-04-05 | Therapeuticsmd, Inc. | Natural combination hormone replacement formulations and therapies |
PT2782584T (pt) | 2011-11-23 | 2021-09-02 | Therapeuticsmd Inc | Preparações e terapias de substituição para hormonoterapias naturais combinadas |
FR2988610B1 (fr) * | 2012-03-30 | 2014-10-31 | Effik | Progestatif co-micronise avec un polymere portant le groupe pyrrolidone, composition et utilisations |
US10806740B2 (en) | 2012-06-18 | 2020-10-20 | Therapeuticsmd, Inc. | Natural combination hormone replacement formulations and therapies |
US20130338122A1 (en) | 2012-06-18 | 2013-12-19 | Therapeuticsmd, Inc. | Transdermal hormone replacement therapies |
US10806697B2 (en) | 2012-12-21 | 2020-10-20 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
US20150196640A1 (en) | 2012-06-18 | 2015-07-16 | Therapeuticsmd, Inc. | Progesterone formulations having a desirable pk profile |
FR2997627B1 (fr) | 2012-11-08 | 2015-01-16 | Hra Pharma Lab | Produit de co-micronisation comprenant de l'ulipristal acetate |
EP2934484A1 (en) | 2012-12-19 | 2015-10-28 | Kashiv Pharma, LLC | Supersaturated stabilized nanoparticles for poorly soluble drugs |
US11266661B2 (en) | 2012-12-21 | 2022-03-08 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
US10537581B2 (en) | 2012-12-21 | 2020-01-21 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
US10568891B2 (en) | 2012-12-21 | 2020-02-25 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
US10471072B2 (en) | 2012-12-21 | 2019-11-12 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
US11246875B2 (en) | 2012-12-21 | 2022-02-15 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
US9180091B2 (en) | 2012-12-21 | 2015-11-10 | Therapeuticsmd, Inc. | Soluble estradiol capsule for vaginal insertion |
RU2016143081A (ru) | 2014-05-22 | 2018-06-26 | Терапьютиксмд, Инк. | Натуральные комбинированные гормонозаместительные составы и терапии |
BR112016029338A2 (pt) | 2014-07-29 | 2017-08-22 | Therapeuticsmd Inc | creme transdérmico |
BR112017027688A2 (pt) | 2015-06-22 | 2018-09-04 | Lipocine Inc | Composições orais que contêm éster de 17- hidroxiprogesterona e métodos relacionados |
US10328087B2 (en) | 2015-07-23 | 2019-06-25 | Therapeuticsmd, Inc. | Formulations for solubilizing hormones |
US10286077B2 (en) | 2016-04-01 | 2019-05-14 | Therapeuticsmd, Inc. | Steroid hormone compositions in medium chain oils |
CA3020153A1 (en) | 2016-04-01 | 2017-10-05 | Therapeuticsmd, Inc. | Steroid hormone pharmaceutical composition |
US11633405B2 (en) | 2020-02-07 | 2023-04-25 | Therapeuticsmd, Inc. | Steroid hormone pharmaceutical formulations |
Family Cites Families (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2408345A1 (fr) * | 1976-11-30 | 1979-06-08 | Besins Jean Louis | Nouvelle composition a action anti-conceptionnelle |
US5276022A (en) * | 1987-09-24 | 1994-01-04 | Jencap Research Ltd. | Hormone preparation and method |
EP0335970B1 (en) | 1987-10-05 | 1992-09-02 | Pharmagyn, Inc. | Tablet for use in the treatment of progesterone deficiency |
FR2627696B1 (fr) * | 1988-02-26 | 1991-09-13 | Fournier Innovation Synergie | Nouvelle forme galenique du fenofibrate |
US5084277A (en) * | 1988-08-30 | 1992-01-28 | Greco John C | Vaginal progesterone tablet |
US5116619A (en) * | 1988-08-30 | 1992-05-26 | Lee Roy Morgan | Vaginal progesterone tablet |
US5976570A (en) * | 1993-12-21 | 1999-11-02 | Applied Analytical Industries, Inc. | Method for preparing low dose pharmaceutical products |
FR2757397B1 (fr) * | 1996-12-23 | 1999-03-05 | Mazal Pharma | Composition pharmaceutique a base de rheine ou de diacerheine a biodisponibilite amelioree |
DE19734538C1 (de) * | 1997-07-30 | 1998-12-24 | Jenapharm Gmbh | Bioadhäsive Tablette |
FR2772617B1 (fr) * | 1997-12-19 | 2001-03-09 | Besins Iscovesco Lab | Comprime de progesterone et son procede de preparation |
FR2775599B1 (fr) | 1998-03-09 | 2001-08-17 | Besins Iscovesco Lab | Composition pharmaceutique a base de progesterone naturelle de synthese et d'oestradiol et son procede de preparation |
IL127129A (en) * | 1998-11-18 | 2004-06-01 | Ferring Bv | Method for preparation of progesterone tablets for vaginal delivery and tablets so prepared |
TW417902U (en) * | 1998-12-31 | 2001-01-01 | Hon Hai Prec Ind Co Ltd | Cable connector |
US6544553B1 (en) * | 1999-12-28 | 2003-04-08 | Watson Pharmaceuticals, Inc. | Dosage forms and methods for oral delivery of progesterone |
-
2001
- 2001-03-01 FR FR0102814A patent/FR2821555B1/fr not_active Expired - Fee Related
-
2002
- 2002-02-27 DE DE60206883T patent/DE60206883T2/de not_active Expired - Lifetime
- 2002-02-27 CA CA002445308A patent/CA2445308A1/fr not_active Abandoned
- 2002-02-27 AT AT02708426T patent/ATE307593T1/de active
- 2002-02-27 US US10/469,441 patent/US7163699B2/en not_active Expired - Lifetime
- 2002-02-27 ES ES02708426T patent/ES2251577T3/es not_active Expired - Lifetime
- 2002-02-27 EP EP02708426A patent/EP1363641B1/fr not_active Expired - Lifetime
- 2002-02-27 WO PCT/FR2002/000714 patent/WO2002069978A1/fr not_active Application Discontinuation
- 2002-02-27 DK DK02708426T patent/DK1363641T3/da active
-
2006
- 2006-07-11 US US11/483,983 patent/US20070042038A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
ATE307593T1 (de) | 2005-11-15 |
FR2821555B1 (fr) | 2003-05-16 |
US7163699B2 (en) | 2007-01-16 |
ES2251577T3 (es) | 2006-05-01 |
EP1363641B1 (fr) | 2005-10-26 |
US20070042038A1 (en) | 2007-02-22 |
CA2445308A1 (fr) | 2002-09-12 |
EP1363641A1 (fr) | 2003-11-26 |
FR2821555A1 (fr) | 2002-09-06 |
DE60206883D1 (de) | 2005-12-01 |
DE60206883T2 (de) | 2006-07-27 |
US20040131553A1 (en) | 2004-07-08 |
WO2002069978A1 (fr) | 2002-09-12 |
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