DK1351972T3 - Lipider omfattende en aminoxygruppe - Google Patents

Lipider omfattende en aminoxygruppe

Info

Publication number
DK1351972T3
DK1351972T3 DK01270543T DK01270543T DK1351972T3 DK 1351972 T3 DK1351972 T3 DK 1351972T3 DK 01270543 T DK01270543 T DK 01270543T DK 01270543 T DK01270543 T DK 01270543T DK 1351972 T3 DK1351972 T3 DK 1351972T3
Authority
DK
Denmark
Prior art keywords
lipids
oxy group
amine oxy
amine
group
Prior art date
Application number
DK01270543T
Other languages
English (en)
Inventor
Michael Jorgensen
Michael Keller
Andrew David Miller
Eric Perouzel
Original Assignee
Mitsubishi Chem Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/GB2000/004767 external-priority patent/WO2001048233A1/en
Priority claimed from GB0113781A external-priority patent/GB2372502B/en
Application filed by Mitsubishi Chem Corp filed Critical Mitsubishi Chem Corp
Application granted granted Critical
Publication of DK1351972T3 publication Critical patent/DK1351972T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/87Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • C12N15/88Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation using microencapsulation, e.g. using amphiphile liposome vesicle
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/15Oximes (>C=N—O—); Hydrazines (>N—N<); Hydrazones (>N—N=) ; Imines (C—N=C)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/575Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/127Liposomes
    • A61K9/1271Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers
    • A61K9/1272Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers with substantial amounts of non-phosphatidyl, i.e. non-acylglycerophosphate, surfactants as bilayer-forming substances, e.g. cationic lipids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J41/00Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J41/00Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0055Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the 17-beta position being substituted by an uninterrupted chain of at least three carbon atoms which may or may not be branched, e.g. cholane or cholestane derivatives, optionally cyclised, e.g. 17-beta-phenyl or 17-beta-furyl derivatives
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/64General methods for preparing the vector, for introducing it into the cell or for selecting the vector-containing host
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Molecular Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biophysics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Cell Biology (AREA)
  • Dispersion Chemistry (AREA)
  • Steroid Compounds (AREA)
  • Medicinal Preparation (AREA)
DK01270543T 2000-12-12 2001-12-05 Lipider omfattende en aminoxygruppe DK1351972T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
PCT/GB2000/004767 WO2001048233A1 (en) 1999-12-23 2000-12-12 Viral core protein-cationic lipid-nucleic acid-delivery complexes
GB0113781A GB2372502B (en) 2000-12-12 2001-06-06 Carbohydrate compounds containing cholesterol and their use

Publications (1)

Publication Number Publication Date
DK1351972T3 true DK1351972T3 (da) 2006-05-08

Family

ID=9916033

Family Applications (1)

Application Number Title Priority Date Filing Date
DK01270543T DK1351972T3 (da) 2000-12-12 2001-12-05 Lipider omfattende en aminoxygruppe

Country Status (4)

Country Link
US (2) US20020188023A1 (da)
EP (1) EP1377673A2 (da)
CZ (2) CZ20031636A3 (da)
DK (1) DK1351972T3 (da)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NO328803B1 (no) * 2000-03-03 2010-05-18 Thia Medica Nye fettsyreanaloger
CA2490121C (en) * 2002-06-20 2013-01-08 Ic Vec Limited Modified phospholipids
DE10236146A1 (de) * 2002-07-31 2004-02-19 Basf Coatings Ag Beschichtungsstoff, Verfahren zu seiner Herstellung und seine Verwendung
EP1638610B1 (en) * 2003-06-18 2015-03-18 Yissum Research Development Company Of The Hebrew University Of Jerusalem Sphingoid polyalkylamine conjugates for vaccination
US7906122B2 (en) * 2003-06-18 2011-03-15 Yissum Research Development Company Of The Hebrew University Of Jersusalem Sphingoid polyalkylamine conjugates for Hepatitis B virus vaccination
GB0418172D0 (en) * 2004-08-13 2004-09-15 Ic Vec Ltd Vector

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL31160A0 (en) * 1967-12-04 1969-01-29 Bayer Ag Basically substituted oximes of 5h-dibenzo-(a,d)-10,11-dihydro-cyclohepten-5-one and their production
NL6818074A (da) * 1968-12-17 1970-06-19
GB1322987A (en) * 1969-12-29 1973-07-11 Richter Gedeon Vegyeszet On,n-diacylhydroxylamine derivatives and preparation
US4189431A (en) * 1975-08-04 1980-02-19 The Board of Trustees of Leland Stanford Junior University Alkinyl terminating groups in biogenetic-like cyclizations to steroids
JPH0198494A (ja) * 1987-10-09 1989-04-17 Agency Of Ind Science & Technol バイオリアクター
US5283185A (en) * 1991-08-28 1994-02-01 University Of Tennessee Research Corporation Method for delivering nucleic acids into cells
US5510510A (en) * 1994-05-10 1996-04-23 Bristol-Meyers Squibb Company Inhibitors of farnesyl protein transferase
US5837533A (en) * 1994-09-28 1998-11-17 American Home Products Corporation Complexes comprising a nucleic acid bound to a cationic polyamine having an endosome disruption agent
US5668272A (en) * 1995-06-30 1997-09-16 National Research Council Of Canada Method for producing synthetic N-linked glycoconjugates

Also Published As

Publication number Publication date
CZ20031637A3 (cs) 2003-11-12
US20020188023A1 (en) 2002-12-12
CZ298560B6 (cs) 2007-11-07
CZ20031636A3 (cs) 2003-11-12
EP1377673A2 (en) 2004-01-07
US20040081687A1 (en) 2004-04-29

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