DK134818B - Fremgangsmåde til fremstilling af steroidspirolactoner. - Google Patents

Fremgangsmåde til fremstilling af steroidspirolactoner.

Info

Publication number
DK134818B
DK134818B DK62574AA DK62574A DK134818B DK 134818 B DK134818 B DK 134818B DK 62574A A DK62574A A DK 62574AA DK 62574 A DK62574 A DK 62574A DK 134818 B DK134818 B DK 134818B
Authority
DK
Denmark
Prior art keywords
spirolactones
steroid
preparation
steroid spirolactones
Prior art date
Application number
DK62574AA
Other languages
Danish (da)
English (en)
Other versions
DK134818C (sv
Inventor
Julien Warnant
Jean Jolly
Original Assignee
Roussel Uclaf
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roussel Uclaf filed Critical Roussel Uclaf
Priority to DK443975A priority Critical patent/DK136828B/da
Priority to DK444075A priority patent/DK444075A/da
Publication of DK134818B publication Critical patent/DK134818B/da
Application granted granted Critical
Publication of DK134818C publication Critical patent/DK134818C/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J21/00Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10Antioedematous agents; Diuretics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DK62574AA 1973-02-06 1974-02-06 Fremgangsmåde til fremstilling af steroidspirolactoner. DK134818B (da)

Priority Applications (2)

Application Number Priority Date Filing Date Title
DK443975A DK136828B (da) 1973-02-06 1975-10-02 Steroidspirolactoner til brug som mellemprodukter ved fremstillingen af gamma-lactonen af 7-acylthio-17beta-hydroxy-delta4-steroido-3-on-21-carboxylsyre.
DK444075A DK444075A (da) 1973-02-06 1975-10-02 Fremgangsmade til fremstilling af et mellemprodukt,spiro-( (7alfa-acylthio-delta4-steroido-3-on)-17beta,2'-(4'-alkyloxyarbonyl-1'-oxacyclopentan-5'-on) ), til fremstilling af gamma-lactonen af 7-acylthio-17beta-hydroxydelta4-steroido-3-on-21- carboxylsyre

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7304057A FR2216273B1 (sv) 1973-02-06 1973-02-06

Publications (2)

Publication Number Publication Date
DK134818B true DK134818B (da) 1977-01-24
DK134818C DK134818C (sv) 1977-06-13

Family

ID=9114388

Family Applications (1)

Application Number Title Priority Date Filing Date
DK62574AA DK134818B (da) 1973-02-06 1974-02-06 Fremgangsmåde til fremstilling af steroidspirolactoner.

Country Status (14)

Country Link
US (1) US3897417A (sv)
JP (1) JPS5829320B2 (sv)
AT (1) AT336811B (sv)
BE (1) BE810643A (sv)
CA (1) CA1026318A (sv)
CH (2) CH609710A5 (sv)
DK (1) DK134818B (sv)
ES (2) ES422921A1 (sv)
FR (1) FR2216273B1 (sv)
GB (1) GB1451843A (sv)
IE (1) IE39329B1 (sv)
LU (1) LU69328A1 (sv)
NL (1) NL179288C (sv)
SE (2) SE399270B (sv)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4058522A (en) * 1973-07-09 1977-11-15 Richter Gedeon Vegyeszeti Gyar Rt. Steroids effective against heavy-metal poisoning
IT1130924B (it) * 1980-03-06 1986-06-18 Secifarma Spa Procedimento per la preparazione di spironolattone micronizzato
US4501695A (en) * 1983-05-16 1985-02-26 The Upjohn Company Spironalactone process
DE69637140T2 (de) * 1995-12-11 2008-04-10 G.D. Searle Llc, Chicago Verfahren zur herstellung einer epoxy-verbindung
US6887991B1 (en) * 1996-12-11 2005-05-03 G. D. Searle & Company Processes for preparation of 9, 11-epoxy steroids and intermediates useful therein
BR9714510A (pt) 1996-12-11 2000-11-28 Searle & Co Processo e preparo de esteróides de 9,11-époxi e intermediários úteis dos mesmos
TWI283245B (en) * 2002-03-22 2007-07-01 Upjohn Co Processes to prepare eplerenone
US7235655B2 (en) * 2002-03-22 2007-06-26 Pharmacia & Upjohn Company Processes to prepare eplerenone
DE102005049393B4 (de) * 2005-10-15 2019-08-08 Kennametal Widia Produktions Gmbh & Co. Kg Verfahren zur Herstellung eines beschichteten Substratkörpers, Substratkörper mit einer Beschichtung und Verwendung des beschichteten Substratkörpers

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1329570A (fr) * 1959-12-10 1963-06-14 Searle & Co Procédé de préparation des lactones d'alcanoylthio-17alpha-carboxyéthyl-17bêta-hydroxy-3-oxoandrostènes
US3257390A (en) * 1963-06-12 1966-06-21 Merck & Co Inc Ring a unsaturated 21-hydroxy-3-oxo-17alpha-pregnane-17-carboxylic acid lactone diuretic agents
US3300489A (en) * 1964-07-24 1967-01-24 Smith Kline French Lab Steroidal c-17 spirolactones and processes and intermediates used in the preparation thereof

Also Published As

Publication number Publication date
US3897417A (en) 1975-07-29
ES422921A1 (es) 1976-09-16
SE399270B (sv) 1978-02-06
ES444112A1 (es) 1977-08-16
ATA92174A (de) 1976-09-15
NL179288C (nl) 1986-08-18
JPS49109365A (sv) 1974-10-17
CH595399A5 (sv) 1978-02-15
NL179288B (nl) 1986-03-17
CH609710A5 (sv) 1979-03-15
FR2216273A1 (sv) 1974-08-30
FR2216273B1 (sv) 1977-07-22
IE39329B1 (en) 1978-09-13
GB1451843A (en) 1976-10-06
AU6521174A (en) 1975-08-07
SE440782B (sv) 1985-08-19
NL7401656A (sv) 1974-08-08
JPS5829320B2 (ja) 1983-06-22
IE39329L (en) 1974-08-06
AT336811B (de) 1977-05-25
CA1026318A (en) 1978-02-14
BE810643A (fr) 1974-08-05
LU69328A1 (sv) 1974-09-25
SE7706509L (sv) 1977-06-03
DK134818C (sv) 1977-06-13

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Legal Events

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