DK134915B - Analogifremgangsmåde til fremstilling af N-halogenalkyl-N-nitrosocarbamater eller N4-halogenalkyl-N4-nitrosoallophanater af steroidforbindelser. - Google Patents

Analogifremgangsmåde til fremstilling af N-halogenalkyl-N-nitrosocarbamater eller N4-halogenalkyl-N4-nitrosoallophanater af steroidforbindelser.

Info

Publication number
DK134915B
DK134915B DK114474AA DK114474A DK134915B DK 134915 B DK134915 B DK 134915B DK 114474A A DK114474A A DK 114474AA DK 114474 A DK114474 A DK 114474A DK 134915 B DK134915 B DK 134915B
Authority
DK
Denmark
Prior art keywords
haloalkyl
nitrosoallophanates
nitrosocarbamates
preparation
steroid compounds
Prior art date
Application number
DK114474AA
Other languages
English (en)
Other versions
DK134915C (da
Inventor
Knut Bertil Hoegberg
Hans Jacob Fex
Imre Koenyves
Anders Robert Stamvik
Original Assignee
Leo Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Leo Ab filed Critical Leo Ab
Publication of DK134915B publication Critical patent/DK134915B/da
Application granted granted Critical
Publication of DK134915C publication Critical patent/DK134915C/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J41/00Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/005Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the 17-beta position being substituted by an uninterrupted chain of only two carbon atoms, e.g. pregnane derivatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J41/00Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0038Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 with an androstane skeleton, including 18- or 19-substituted derivatives, 18-nor derivatives and also derivatives where position 17-beta is substituted by a carbon atom not directly bonded to a further carbon atom and not being part of an amide group
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J41/00Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0044Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 with an estrane or gonane skeleton, including 18-substituted derivatives and derivatives where position 17-beta is substituted by a carbon atom not directly bonded to another carbon atom and not being part of an amide group
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J41/00Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0055Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the 17-beta position being substituted by an uninterrupted chain of at least three carbon atoms which may or may not be branched, e.g. cholane or cholestane derivatives, optionally cyclised, e.g. 17-beta-phenyl or 17-beta-furyl derivatives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J41/00Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0072Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the A ring of the steroid being aromatic

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Transplantation (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK114474AA 1973-03-05 1974-03-04 Analogifremgangsmåde til fremstilling af N-halogenalkyl-N-nitrosocarbamater eller N4-halogenalkyl-N4-nitrosoallophanater af steroidforbindelser. DK134915B (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB1061373A GB1458372A (en) 1973-03-05 1973-03-05 Steroid carbamates and allophanates

Publications (2)

Publication Number Publication Date
DK134915B true DK134915B (da) 1977-02-07
DK134915C DK134915C (da) 1977-06-27

Family

ID=9971097

Family Applications (1)

Application Number Title Priority Date Filing Date
DK114474AA DK134915B (da) 1973-03-05 1974-03-04 Analogifremgangsmåde til fremstilling af N-halogenalkyl-N-nitrosocarbamater eller N4-halogenalkyl-N4-nitrosoallophanater af steroidforbindelser.

Country Status (18)

Country Link
US (1) US3963707A (da)
JP (1) JPS5613720B2 (da)
AT (1) AT343293B (da)
BE (1) BE811775A (da)
CA (1) CA1034941A (da)
CH (1) CH606109A5 (da)
DE (1) DE2409436A1 (da)
DK (1) DK134915B (da)
ES (1) ES423694A1 (da)
FI (1) FI53578C (da)
FR (1) FR2220261B1 (da)
GB (1) GB1458372A (da)
HU (1) HU168811B (da)
IE (1) IE38909B1 (da)
NL (1) NL7402961A (da)
NO (1) NO740747L (da)
SE (1) SE401513B (da)
SU (1) SU512714A3 (da)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1523035A (en) * 1976-03-10 1978-08-31 Leo Ab Derivatives of estradiol - 17 - dihydrogen phosphates
US4261910A (en) * 1978-08-14 1981-04-14 Kureha Kagaku Kogyo Kabushiki Kaisha Process for the preparation of Chlorambucil derivatives
DE3210637A1 (de) * 1982-03-23 1983-09-29 Stiftung Deutsches Krebsforschungszentrum, 6900 Heidelberg Steroidester von n-(2-halogenethyl)-n-nitroso-carbamoylaminosaeuren und deren peptiden, sowie verfahren zu deren herstellung
JPS61293993A (ja) * 1985-06-21 1986-12-24 Kureha Chem Ind Co Ltd 新規な螢光物質,その製造方法及び薬剤
US5792758A (en) * 1995-12-08 1998-08-11 G. D. Searle & Co. Steroid nitrite ester derivatives useful as anti-inflammatory drugs
US5912240A (en) * 1997-04-10 1999-06-15 Loria; Roger M. 5-androstene 3β, 17α diol as an inhibitor of tumor growth
IT1311922B1 (it) * 1999-04-13 2002-03-20 Nicox Sa Composti farmaceutici.

Also Published As

Publication number Publication date
ES423694A1 (es) 1976-04-16
IE38909L (en) 1974-09-05
FI53578C (fi) 1978-06-12
DE2409436A1 (de) 1974-09-12
JPS5029549A (da) 1975-03-25
FR2220261A1 (da) 1974-10-04
CA1034941A (en) 1978-07-18
HU168811B (da) 1976-07-28
ATA181074A (de) 1977-09-15
DK134915C (da) 1977-06-27
CH606109A5 (da) 1978-10-13
AT343293B (de) 1978-05-26
BE811775A (fr) 1974-07-01
US3963707A (en) 1976-06-15
NO740747L (no) 1974-09-06
SE401513B (sv) 1978-05-16
GB1458372A (en) 1976-12-15
IE38909B1 (en) 1978-06-21
FI53578B (da) 1978-02-28
NL7402961A (da) 1974-09-09
JPS5613720B2 (da) 1981-03-30
FR2220261B1 (da) 1978-02-03
SU512714A3 (ru) 1976-04-30

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