DK1335725T3 - Anvendelse af CCI-779 som et antineoplastisk middel - Google Patents

Anvendelse af CCI-779 som et antineoplastisk middel

Info

Publication number
DK1335725T3
DK1335725T3 DK01996175T DK01996175T DK1335725T3 DK 1335725 T3 DK1335725 T3 DK 1335725T3 DK 01996175 T DK01996175 T DK 01996175T DK 01996175 T DK01996175 T DK 01996175T DK 1335725 T3 DK1335725 T3 DK 1335725T3
Authority
DK
Denmark
Prior art keywords
cci
antineoplastic agent
antineoplastic
agent
Prior art date
Application number
DK01996175T
Other languages
English (en)
Inventor
Gary Dukart
James Joseph Gibbons Jr
Lisa Anne Speicher
Carolyn Mary Discafani-Marro
Philip Frost
Original Assignee
Wyeth Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wyeth Corp filed Critical Wyeth Corp
Application granted granted Critical
Publication of DK1335725T3 publication Critical patent/DK1335725T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/436—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having oxygen as a ring hetero atom, e.g. rapamycin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK01996175T 2000-11-15 2001-11-13 Anvendelse af CCI-779 som et antineoplastisk middel DK1335725T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US24907700P 2000-11-15 2000-11-15
PCT/US2001/047324 WO2002040000A2 (en) 2000-11-15 2001-11-13 Use of cci-779 as an antineoplastic agent

Publications (1)

Publication Number Publication Date
DK1335725T3 true DK1335725T3 (da) 2008-06-30

Family

ID=22941961

Family Applications (1)

Application Number Title Priority Date Filing Date
DK01996175T DK1335725T3 (da) 2000-11-15 2001-11-13 Anvendelse af CCI-779 som et antineoplastisk middel

Country Status (28)

Country Link
US (3) US20020091137A1 (da)
EP (1) EP1335725B1 (da)
JP (4) JP4472251B2 (da)
KR (1) KR100827942B1 (da)
CN (2) CN102058588A (da)
AR (1) AR031341A1 (da)
AT (1) ATE393629T1 (da)
AU (2) AU2731302A (da)
BR (1) BR0115323A (da)
CA (1) CA2429020C (da)
CY (1) CY1108109T1 (da)
DE (1) DE60133831T2 (da)
DK (1) DK1335725T3 (da)
EA (1) EA007096B1 (da)
ES (1) ES2305134T3 (da)
HK (1) HK1058008A1 (da)
HU (1) HUP0400521A3 (da)
IL (2) IL155871A0 (da)
MX (1) MXPA03004192A (da)
NO (1) NO20032181L (da)
NZ (1) NZ539668A (da)
PL (1) PL207061B1 (da)
PT (1) PT1335725E (da)
SG (1) SG148031A1 (da)
SI (1) SI1335725T1 (da)
TW (1) TWI286074B (da)
WO (1) WO2002040000A2 (da)
ZA (1) ZA200304603B (da)

Families Citing this family (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5362718A (en) 1994-04-18 1994-11-08 American Home Products Corporation Rapamycin hydroxyesters
TWI286074B (en) * 2000-11-15 2007-09-01 Wyeth Corp Pharmaceutical composition containing CCI-779 as an antineoplastic agent
DK3143995T3 (da) 2001-02-19 2019-01-28 Novartis Pharma Ag Rapamycinderivat til behandling af lungecancer
TWI296196B (en) * 2001-04-06 2008-05-01 Wyeth Corp Antineoplastic combinations
NZ529877A (en) * 2001-06-01 2006-08-31 Wyeth Corp Antineoplastic combinations
US20020198137A1 (en) * 2001-06-01 2002-12-26 Wyeth Antineoplastic combinations
JP4547911B2 (ja) * 2002-02-01 2010-09-22 アリアド・ファーマシューティカルズ・インコーポレイテッド リン含有化合物およびその用途
EP1516597A4 (en) * 2002-06-27 2010-11-10 Microport Medical Shanghai Co MEDICINES ELUTIONSSTENT
BR0313024A (pt) 2002-07-30 2005-07-12 Wyeth Corp Formulações parenterais contendo um hidroxiéster de rapamicina
CA2496332A1 (en) * 2002-09-17 2004-04-01 Wyeth Oral formulations
MXPA05005283A (es) 2002-11-21 2005-07-25 Wyeth Corp Metodos para diagnostico de rcc y otros tumores solidos.
CA2515677A1 (en) * 2003-02-11 2004-08-26 Wyeth Methods for monitoring drug activities in vivo
US7643943B2 (en) 2003-02-11 2010-01-05 Wyeth Llc Methods for monitoring drug activities in vivo
US20050287532A9 (en) * 2003-02-11 2005-12-29 Burczynski Michael E Methods for monitoring drug activities in vivo
UA83484C2 (uk) * 2003-03-05 2008-07-25 Уайт Спосіб лікування раку грудей комбінацією похідного рапаміцину і інгібітора ароматази - летрозолу, фармацевтична композиція
BRPI0409632A (pt) * 2003-04-22 2006-04-25 Wyeth Corp combinações antineoplásticas
AU2004235395A1 (en) * 2003-04-29 2004-11-11 Wyeth Methods for prognosis and treatment of solid tumors
SG144165A1 (en) * 2003-07-25 2008-07-29 Wyeth Corp Cci-779 lyophilized formulations
AR046194A1 (es) * 2003-11-04 2005-11-30 Mayo Foundation Metodo de tratamiento del linfoma de celulas del manto
ES2298861T3 (es) * 2004-01-08 2008-05-16 Wyeth Composicion farmaceutica que puede obtenerse mediante compresion directa para la administracion oral de cci-779.
AR047988A1 (es) * 2004-03-11 2006-03-15 Wyeth Corp Combinaciones antineoplásicas de cci-779 y rituximab
CN102886045A (zh) * 2005-02-03 2013-01-23 综合医院公司 治疗吉非替尼耐药性癌症的方法
US20060183766A1 (en) * 2005-02-15 2006-08-17 Wyeth Orally bioavailable CCI-779 formulations
EP3488866A1 (en) * 2005-11-04 2019-05-29 Wyeth LLC Antineoplastic combinations with mtor inhibitor, herceptin, and/or hki-272
DK2275103T3 (da) * 2005-11-21 2014-07-07 Novartis Ag mTor-inhibitorer ved behandling af endokrine tumorer
AU2006331874A1 (en) * 2005-12-20 2007-07-05 Wyeth Control of CCI-779 dosage form stability through control of drug substance impurities
DE102006011507A1 (de) * 2006-03-14 2007-09-20 Lts Lohmann Therapie-Systeme Ag Wirkstoffbeladene Nanopartikel auf Basis hydrophiler Proteine
TW200901989A (en) 2007-04-10 2009-01-16 Wyeth Corp Anti-tumor activity of CCI-779 in papillary renal cell cancer
US20090076060A1 (en) * 2007-09-17 2009-03-19 Protia, Llc Deuterium-enriched temsirolimus
US8660003B2 (en) * 2007-10-03 2014-02-25 Genesis Technical Systems Corp. Dynamic, asymmetric rings
US8022216B2 (en) 2007-10-17 2011-09-20 Wyeth Llc Maleate salts of (E)-N-{4-[3-chloro-4-(2-pyridinylmethoxy)anilino]-3-cyano-7-ethoxy-6-quinolinyl}-4-(dimethylamino)-2-butenamide and crystalline forms thereof
AU2009225434B2 (en) * 2008-03-21 2014-05-22 The University Of Chicago Treatment with opioid antagonists and mTOR inhibitors
AU2013205002B2 (en) * 2008-03-21 2016-09-15 The University Of Chicago Treatment with opioid antagonists and mTOR inhibitors
US20090312360A1 (en) 2008-06-17 2009-12-17 Wyeth Antineoplastic Combinations Containing HKI-272 and Vinorelbine
JP5681108B2 (ja) 2008-08-04 2015-03-04 ワイス・エルエルシー ４−アニリノ−３−シアノキノリンとカペシタビンの抗新生物薬の組合せ
CA2755789C (en) 2009-04-06 2016-01-19 Wyeth Llc Treatment regimen utilizing neratinib for breast cancer
WO2010132233A1 (en) * 2009-05-13 2010-11-18 The Trustees Of The University Of Pennsylvania Combination antineoplastic therapy
AU2011260016B2 (en) * 2010-06-02 2013-08-22 Fresenius Kabi Oncology Ltd. Stable pharmaceutical compositions of Rapamycin esters
US9745941B2 (en) * 2014-04-29 2017-08-29 Ford Global Technologies, Llc Tunable starter resistor
US10300026B2 (en) * 2015-08-24 2019-05-28 Shanxi Yabao Health Products Co., Ltd. Use of dihydroxyacetone in preparation of anti-cancer medicaments
CN111110676A (zh) * 2020-03-07 2020-05-08 天津医科大学总医院 阿帕替尼及联合cci-779在制备肺癌药物中的应用

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA737247B (en) 1972-09-29 1975-04-30 Ayerst Mckenna & Harrison Rapamycin and process of preparation
US3993749A (en) 1974-04-12 1976-11-23 Ayerst Mckenna And Harrison Ltd. Rapamycin and process of preparation
US4885171A (en) 1978-11-03 1989-12-05 American Home Products Corporation Use of rapamycin in treatment of certain tumors
BE877700A (fr) * 1978-11-03 1980-01-14 Ayerst Mckenna & Harrison Compositions pharmaceutiques a base de rapamycine pour le traitement de tumeurs carcinogenes
US5206018A (en) 1978-11-03 1993-04-27 Ayerst, Mckenna & Harrison, Inc. Use of rapamycin in treatment of tumors
US4401653A (en) 1981-03-09 1983-08-30 Ayerst, Mckenna & Harrison Inc. Combination of rapamycin and picibanil for the treatment of tumors
US5100899A (en) 1989-06-06 1992-03-31 Roy Calne Methods of inhibiting transplant rejection in mammals using rapamycin and derivatives and prodrugs thereof
US5080899A (en) 1991-02-22 1992-01-14 American Home Products Corporation Method of treating pulmonary inflammation
US5078999A (en) 1991-02-22 1992-01-07 American Home Products Corporation Method of treating systemic lupus erythematosus
US5321009A (en) 1991-04-03 1994-06-14 American Home Products Corporation Method of treating diabetes
SG43072A1 (en) 1991-06-18 1997-10-17 American Home Prod Method of treating adult t-cell leukemia/lymphoma
ZA924953B (en) 1991-07-25 1993-04-28 Univ Louisville Res Found Method of treating ocular inflammation
US5286731A (en) 1991-09-17 1994-02-15 American Home Products Corporation Method of treating immunoinflammatory bowel disease
US5286730A (en) 1991-09-17 1994-02-15 American Home Products Corporation Method of treating immunoinflammatory disease
US5516781A (en) 1992-01-09 1996-05-14 American Home Products Corporation Method of treating restenosis with rapamycin
US5288711A (en) 1992-04-28 1994-02-22 American Home Products Corporation Method of treating hyperproliferative vascular disease
ZA935112B (en) 1992-07-17 1994-02-08 Smithkline Beecham Corp Rapamycin derivatives
US5362718A (en) * 1994-04-18 1994-11-08 American Home Products Corporation Rapamycin hydroxyesters
US5561138A (en) 1994-12-13 1996-10-01 American Home Products Corporation Method of treating anemia
US5496832A (en) 1995-03-09 1996-03-05 American Home Products Corporation Method of treating cardiac inflammatory disease
US6511986B2 (en) 2000-08-11 2003-01-28 Wyeth Method of treating estrogen receptor positive carcinoma
TWI286074B (en) * 2000-11-15 2007-09-01 Wyeth Corp Pharmaceutical composition containing CCI-779 as an antineoplastic agent
TWI233359B (en) 2001-04-06 2005-06-01 Wyeth Corp Pharmaceutical composition for treating neoplasm
TWI296196B (en) 2001-04-06 2008-05-01 Wyeth Corp Antineoplastic combinations
UA77200C2 (en) 2001-08-07 2006-11-15 Wyeth Corp Antineoplastic combination of cci-779 and bkb-569

Also Published As

Publication number Publication date
HUP0400521A2 (hu) 2004-06-28
ATE393629T1 (de) 2008-05-15
ES2305134T3 (es) 2008-11-01
WO2002040000A2 (en) 2002-05-23
MXPA03004192A (es) 2003-09-22
IL155871A0 (en) 2003-12-23
PL362740A1 (en) 2004-11-02
WO2002040000A3 (en) 2002-09-06
KR20040029309A (ko) 2004-04-06
SI1335725T1 (sl) 2008-08-31
CY1108109T1 (el) 2014-02-12
NO20032181D0 (no) 2003-05-14
CA2429020C (en) 2009-05-26
HK1058008A1 (en) 2004-04-30
US7781446B2 (en) 2010-08-24
EP1335725A2 (en) 2003-08-20
US20020091137A1 (en) 2002-07-11
PL207061B1 (pl) 2010-10-29
TWI286074B (en) 2007-09-01
JP4472251B2 (ja) 2010-06-02
AR031341A1 (es) 2003-09-17
AU2731302A (en) 2002-05-27
CN1678312A (zh) 2005-10-05
DE60133831D1 (de) 2008-06-12
JP2004517065A (ja) 2004-06-10
HUP0400521A3 (en) 2007-05-29
CA2429020A1 (en) 2002-05-23
AU2007201324A1 (en) 2007-04-19
US7189735B2 (en) 2007-03-13
US20030153593A1 (en) 2003-08-14
BR0115323A (pt) 2004-02-17
CN102058588A (zh) 2011-05-18
EP1335725B1 (en) 2008-04-30
JP2016094444A (ja) 2016-05-26
EA200300566A1 (ru) 2003-10-30
DE60133831T2 (de) 2009-05-20
EA007096B1 (ru) 2006-06-30
JP2010018620A (ja) 2010-01-28
JP2014088430A (ja) 2014-05-15
KR100827942B1 (ko) 2008-05-13
AU2007201324B2 (en) 2010-11-18
US20070142425A1 (en) 2007-06-21
NZ539668A (en) 2007-06-29
IL155871A (en) 2012-03-29
SG148031A1 (en) 2008-12-31
ZA200304603B (en) 2004-09-13
NO20032181L (no) 2003-05-14
PT1335725E (pt) 2008-06-19

Similar Documents

Publication Publication Date Title
DK1335725T3 (da) Anvendelse af CCI-779 som et antineoplastisk middel
DK1608407T3 (da) Dispergébar formulering af et antiinflammatorisk middel
DK1250047T3 (da) Herbicidt middel
DK1355904T3 (da) Heterocyclindazol- og -azaindazolforbindelser som 5-hydroxytryptamin-6-ligander
NO20030929D0 (no) Guanidinobenzamider som MC4-R agonister
NO20042955L (no) Substituerte fenylaftalener som estrogene midler
PT1399127E (pt) Formulacoes de olopatadina para administracao topica
DK1438306T3 (da) Derivater af UK-2A
NO20030138D0 (no) Lipidrikt plakkinnkapslende middel
AR028567A1 (es) Nuevos derivados de fenil-propargileter
NO20032531D0 (no) Tetralon-derivater som antitumormidler
NO20026037L (no) Sötvareprodukt som inneholder aktive bestanddeler
AR028596A1 (es) Nuevos derivados de fenilglicina
DK1073416T3 (da) Anvendelse af NO som anti-inflammatorisk middel
NO20033618D0 (no) Ftalayinon-piperidino-derivater som PDE-4-inhibitorer
NO20041316L (no) Tiofen- og tiazoisulfonamider som antineoplastiske midler
DK1337521T3 (da) Salte af en isothiasol-4-carboxamid og deres anvendelse som antihyperproliferationsmiddel
ATE459598T1 (de) Sulfonamidderivate
DK1600441T3 (da) Krystallinsk form af elrcanidipinhydrochlorid til anvendelse som et antihypertensivt middel
NO20021959D0 (no) Tetrahydrotiopyranftalazinon-derivater som PDE4-inhibitorer
DK1268482T3 (da) Pyranoindoler til behandling af glaukom
DZ3344A1 (fr) Derives de sulfonamide
AR028398A1 (es) Ciclipostinas, procedimiento para su preparacion, y utilizacion de las mismas
DZ3343A1 (fr) Derives de sulfonamide
NO20031239L (no) 1-amino-alkylsykloheksaner som trypanocidale midler